• Journal of Radiation Protection and Research
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• v.17 no.1
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• pp.21-30
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• 1992

The frequencies of KCCH cyclotron neutron (30 cGy/min) or $^{60}Co\;{\gamma}-rays$ (210 cGy/min)-induced asymmetrical interchanges (dicentrics and centric rings) and acentric fragments (deletion) at several doses were measured in the normal human peripheral blood lymphocytes Chromosome aberrations were scored at the first nitosis after stimulation with phytohemagglutinin. The neutron and y-ray data were analysed on linear, power-law, quadratic and linear-quadratic model . When the dicentrics and centric rings of ${\gamma}-rays$ datas were pooled and fitted to these model, good fits were obtained to power-law $[Y=(5.81{\pm}1.96){\times}10^6D^{1.93+0.06},\; P=0.931]$, quadratic $[Y=(3.91{\pm}0.09){\times}10^{-6}D^2,\;P=0.972]$ an linear-Quadrati model $[Y=(6.55{\pm}6.83){\times}10^{-5}D+(3.72{\pm}0.22){\times}10^{-6}D^2\; P=0.922]$, except for linear model (P=0.067) As in the case of neutron data, the best fit was obtained to the linear model $(Y=(6.12{\pm}0.17){\times}10^{-3}\;D-0.22,\;P=0.987]$ and good fits were obtained to power-law$[Y=(5.36{\pm}3.02) {\times}10^{-4}D^{1.42+0.11},\; P=0.601]$ and linear-quadratic model$[Y=(2.43{\pm}0.70){\times}10^{-3}D+(1.21{\pm}0.39){\times}10^{-7}D^2$, \;P=0.415], except for quadratic model (P<0.005). The relative biological effectiveness (RBE) of neutron compared with y-ray was estimated by best fitting model. In the asymmetrical interchanges range between 0.1 and 1.5 per cell, the RBE was found to be $2.714{\pm}0.408$.

• Nuclear Engineering and Technology
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• v.53 no.1
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• pp.164-171
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• 2021

The europium sorption on Tamusu clay was investigated by batch sorption experiments and spectroscopic study under the condition of strong ionic strength. The results demonstrated that europium sorption on Tamusu clay increased rapidly with pH value, but decreased with the ionic strength of solution increased. The europium sorption also increased in the presence of humic acid, especially at low pH value. The sorption could be fitted by Freundlich isotherm model and the europium sorption on clay was spontaneous and endothermic reaction. Besides, the result indicates that ion exchange was the main process at low pH value, while inner-sphere surface complexation dominated the sorption process at high pH value. The Backscatter electron scanning/Energy Dispersive Spectrometer(BSE/EDS) and the effect of Na for europium sorption results further suggested that europium sorption on Tamusu clay mainly competed with Na at low pH value. Overall, the results in this research were of significance to understand the sorption behavior of europium on the geological media under high ionic strength.

• Solar Energy
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• v.15 no.3
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• pp.91-103
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• 1995

Non-gray radiation with convection in the entrance region of a smooth tube is numerically investigated. The fluid is a mixture of carbon dioxide, water vapor, and nitrogen to simulate combustion products of propane. The flow is assumed to be laminar and hydrodynamically and thermally developing. The P-1 approximation is used to simplify the radiative transfer equation and the exponential wide band model is adapted to model the spectral absorption coefficients of non-gray gas mixture. The bulk mean temperature and Nusselt number variation along the tube axis are shown for several inlet and wall temperature pairs to show the effect of temperature on the heat transfer characteristics. Nusselt numbers for simultaneously developing flow are compared to those for thermally developing flow. In addition, the effect of the mole fraction of the non-gray gases on convective and radiative Nusselt numbers is investigated.

• Radiation Oncology Journal
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• v.31 no.1
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• pp.25-33
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• 2013

Purpose: We reviewed the treatment outcomes and prognostic factors for patients with anal canal carcinoma who were treated with curative intent chemoradiotherapy (CRT) at Severance Hospital from 2005 to 2011. Materials and Methods: Data for 38 eligible patients treated during this period were reviewed. All patients were treated with curative intent using radiotherapy (RT) with (n = 35) or without concomitant chemotherapy (n = 3). Among 35 patients who received CRT, most of the chemotherapeutic regimens were either 5-fluorouracil (5-FU) plus mitomycin C (23 patients) or 5-FU plus cisplatin (10 patients). Recurrence-free survival (RFS), colostomy-free survival (CFS), overall survival (OS), and locoregional control (LRC) rates were calculated using the Kaplan-Meier method and survival between subgroups were compared using the log-rank test. Cox's proportional hazard model was used for multivariate analysis. Results: Over a median follow-up period of 44 months (range, 11 to 96 months), 3-year RFS, CFS, OS, and LRC were 80%, 79%, 85%, and 92%, respectively. In multivariate analysis, tumor size >4 cm was an independent predicting factor for poorer RFS (hazard ratio [HR], 6.35; 95% confidence interval [CI], 1.42 to 28.5; p = 0.006) and CFS (HR, 6.25; 95% CI, 1.39-28.0; p = 0.017), while the presence of external iliac lymph node metastasis was an independent prognosticator for poorer OS (HR, 9.32; 95% CI, 1.24 to 70.3; p = 0.030). No treatment-related colostomies or deaths occurred during or after treatment. Conclusion: Curative intent CRT resulted in excellent outcomes that were comparable to outcomes in previous randomized trials. No severe treatment-related toxicities were observed.

• Radiation Oncology Journal
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• v.22 no.1
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• pp.40-54
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• 2004

Purpose : Captopril (angiotension converting enzyme inhibitor) is known to have a radioproptective effect in the lungs, intestines and skin, but its effect in the heart is unclear. To investigate the radioprotectlve efiect and mechanism of captopril on the heart, the histopathological changes and immunohistochemical stains were compared with radiation alone, and radiation combined with captopril, in the rats. Materials and Methods : The histopathological changes and immunohistochemical stains ($TNF{\alpha}$, $TGF{\beta}1$, PDGF and FGF2) were examined in the radiation alone and the combined captopril and radiation groups, 2 and 8 weeks after irradiation. Each group consisted of 8 to 10 rats (Sprague-Dawley). Irradiation (12.5 Gy) was given to the left hemithorax in a single fraction. Captopril (50 mg/Kg/d) mixed with water, was given orally and continuously from the first week prior to, up to the 8th week of the experiment. Results : In the radiation alone group, the ventricle at 2 weeks after irradiation showed prominent edema (p=0.082) and fibrin deposit (p=0.018) compared to the control group. At 8 weeks, the edema was decreased and fibrosis increased compared to those at 2 weeks. The histopathological changes of the combined group were similar to those of the control group, due to the reduced radiation toxicity at 2 and 8 weeks. The endocardial fibrin deposit (p=0.047) in the atrium, and the interstitial fibrin deposit (p=0.019) and edema (p=0.042) of the ventricle were reduced significantly in the combined group compared to those in the radiation alone group at 2 weeks. The expressions of $TNF-{\alpha}$, $TGF-{\beta}1$, PDGF and FGF-2 in the radiation alone group were more increased than in the control group, especially in the pericardium and endocardium of the atrium at 2 weeks. At 8 weeks, the pericardial $TNF-{\alpha}$ and $TGF-{\beta}1$ in the radiation alone group continuously increased. The expressions of $TNF-{\alpha}$, $TGF-{\beta}1$ and PDGF were decreased in the combined group at 2 weeks. At 8 weeks, the expressions of $TNF-{\alpha}$ in the atrial and ventricular pericardia were markedly reduced (p=0.049, p=0.009). Conclusion : This study revealed that the early heart damage induced by radiation can be reduced by the addition of captopril in a rat model. The expressions of $TNF-{\alpha}$, $TGF-{\beta}1$ and PDGF were further decreased in the combined compared to the radiation alone group at both 2 and 8 weeks. From these results, it may be concluded that these cytokines probably play roles in the radioprotective mechanism of captopril from the radiation-induced heart toxicity, similarly to in other organs.

• Journal of Environmental Health Sciences
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• v.46 no.1
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• pp.96-102
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• 2020

Objectives: This study identified factors impacting radiation knowledge among aircrew, who are affected by cosmic radiation exposure due to their occupational environment. Methods: In September 2019 we conducted an online survey of aircrew through a Google link. We evaluated the level of radiation knowledge using a ten-item (10 points) questionnaire. The following exploratory variables were evaluated in relationship with the level of radiation knowledge using univariable linear regression models: sex, age, duration of employment, position level, company, marriage, education level, personal/family history of disease, and the number of times acquiring information on radiation through various channels (internet searching, watching television, reading newspaper, conversation about radiation with aircrew/non-aircrew, in-house training). With a p of 0.2 in univariable models, we built a multivariable linear regression model using a stepwise selection method. Results: The average radiation knowledge score of the 356 respondents was 7.22. Univariable linear regression analysis showed that radiation knowledge of the aircrew was associated with their company, position level, age, and number of conversations with other aircrew members. Our multivariable model showed that the radiation knowledge level of aircrew decreased as they had more conversations about radiation with other aircrew members and as their age increased. Conclusions: Korean air crew showed a lower level of radiation knowledge as their age and the number of conversations with colleagues increased. The study suggests that more education is needed in order for aircrew to gain accurate radiation knowledge.

• The Bulletin of The Korean Astronomical Society
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• v.46 no.2
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• pp.38.1-38.1
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• 2021

Dust polarization depends on the physical and mechanical properties of dust, as well as the properties of local environments. To understand how dust polarization varies with grain mechanical properties and the local environment, in this paper, we model the wavelength-dependence polarization of starlight and polarized dust emission by aligned grains by simultaneously taking into account grain alignment and rotational disruption by radiative torques (RATs). We explore a wide range of the local radiation field and grain mechanical properties characterized by tensile strength. We find that the maximum polarization and the peak wavelength shift to shorter wavelengths as the radiation strength U increases due to the enhanced alignment of small grains. Grain rotational disruption by RATs tends to decrease the optical-near infrared polarization but increases the ultraviolet polarization of starlight due to the conversion of large grains into smaller ones. In particular, we find that the submillimeter (submm) polarization degree at 850㎛(P850) does not increase monotonically with the radiation strength or grain temperature (Td), but it depends on the tensile strength of grain materials. Our physical model of dust polarization can be tested with observations toward star-forming regions or molecular clouds irradiated by a nearby star, which have higher radiation intensity than the average interstellar radiation field. Finally, we compare our predictions of the P850-Td relationship with Planck data and find that the observed decrease of P850 with Td can be explained when grain disruption by RATs is accounted for, suggesting that interstellar grains unlikely to have a compact structure but perhaps a composite one. The variation of the submm polarization with U (or Td)can provide a valuable constraint on the internal structures of cosmic dust

• Journal of Korean Society on Water Environment
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• v.24 no.1
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• pp.63-68
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• 2008

This study was performed to assess the potential use of ozone or UV radiation for the treatment of water contaminated with sulfamethoxazole (SMX), which is frequently used antibiotic in human and veterinary medicines, especially focusing on the kinetic study and effect of pH. In a study using ozone alone, kinetic study was performed to determine second-order rate constant ($k_{O3,SMX}$) for the reactions of SMX with ozone, which was found to be $1.9{\times}10^6M^{-1}s^{-1}$ at pH 7. The removal efficiencies of SMX by ozone were decreased with increase of pH due to rapid decomposition of ozone under the condition of various pH (2.5, 5.3, 7, 8, 10). In a UV irradiation study at 254 nm, a kinetic model for direct photolysis of SMX was developed with determination of quantum yield ($0.08mol\;Einstein^{-1}$) and molar extinction coefficient ($15,872M^{-1}cm^{-1}$) values under the condition of quantum shielding due to the presence of reaction by-products formed during photolysis. For effect of pH on photolysis of SMX, SMX in the anionic state ($S^-$, pH > 5.6), most prevalent form at environmentally relevant pH values, degraded more slowly than in the neutral state (SH, 1.85 < pH < 5.6) by UV radiation at 254 nm.

• Journal of Korean Society for Atmospheric Environment
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• v.12 no.3
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• pp.231-241
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• 1996

The effect of radiation and buoyancy on the thermophoresis phenomenon owing to the presence of highly absorbing, emitting particles (such as soot or pulverized coal) suspended in a two phase flow system was investigated numerically for a turbulent mixed convection flow. The analysis of conservation equations for a gas-particle flow system was performed on the basis of a two-fluid model from a continuum Eulerian viewpoint. The modified van Driest and Cebeci mixing length turbulence model was adopted in the anaylsis of turbulent flow. In addition, the P-1 approximation was used to evaluate the radiation heat transfer. As expected from the particle concentration and drift velocity distribution, the cumulative collection efficiency E (x) becomes larger when the buoyancy effect increases (i.e. higher Grashof number), while smaller as the radiation effect increases (i.e. higher optical thickness).

• Food Science and Biotechnology
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• v.17 no.4
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• pp.723-727
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• 2008

The effect of gamma irradiation on the prevention of breeding a patulin-producing mold and reducing patulin content was evaluated in an apple model system. Penicillium griseofulvum, a patulin-producing standard mold strain was artificially inoculated into apples and a gamma irradiation was performed. The $D_{10}$-values of the conidia of P. griseofulvum in an aqueous suspension and the apple model system were calculated at 0.28 and 0.48 kGy, respectively. The viable cell counts of the inoculated conidia in the apples showed 2 decimal point reductions at a dose of 1 kGy. Breeding and growth of the survived conidia was prevented during 10 weeks of post-irradiation storage period, especially at $4^{\circ}C$. The concentration of patulin in the non-irradiated apples was gradually increased and reached about 950 ppm at $25^{\circ}C$ and 410 ppm at $4^{\circ}C$, but the production of patulin was not observed during storage after 1 kGy of gamma irradiation.