• Journal of The Korean Society of Inherited Metabolic disease
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• v.23 no.2
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• pp.1-7
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• 2023

Inherited metabolic disorders (IMD) are a group of disorders involving various metabolic pathways. Genetic diagnosis of IMD has been challenging because of extremely heterogeneous nature and extensive laboratory and/or phenotype overlap. Conventional genetic diagnosis was a gene-by-gene approach that needs a priori information on the causative genes that might underlie the IMD. Recent implementation of next-generation sequencing (NGS) technologies has changed the process of genetic diagnosis from a gene-by-gene approach to simultaneous analysis of targeted genes possibly associated with the IMD using gene panels or using whole exome/genome sequencing (WES/WGS) covering entire human genes. Clinical NGS tests can be a cost-effective approach for the rapid diagnosis of IMD with genetic heterogeneity and are becoming standard diagnostic procedures.

• The Journal of the Acoustical Society of Korea
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• v.22 no.8
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• pp.717-726
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• 2003

This paper presents the methods that design the Wavelet-based pitch detector for 2,4 kbps Harmonic-CELP Coder, and that achieve the effective waveform interpolation by decision window shape of the transition region, Waveform interpolation coder operates by encoding one pitch-period-sized segment, a prototype segment, of speech for each frame, generate the smooth waveform interpolation between the prototype segments for voiced frame, But, harmonic synthesis of the prototype waveforms between previous frame and current frame occur not only waveform errors but also discontinuity at frame boundary on that case of pitch halving or doubling, In addtion, in transition region since waveform interpolation coder synthesizes the excitation waveform by using overlap-add with triangularity window, therefore, Harmonic-CELP fail to model the instantaneous increasing speech and synthesis waveform linearly increases, First of all, in order to detect the precise pitch period, we use the hybrid 1st pitch detector, and increse the precision by using 2nd ACF-pitch detector, Next, in order to modify excitation window, we detect the onset, offset of frame by GCI, As the result, pitch doubling is removed and pitch error rate is decreased 5.4% in comparison with ACF, and is decreased 2,66% in comparison with wavelet detector, MOS test improve 0.13 at transition region.

• Smart Media Journal
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• v.3 no.3
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• pp.26-35
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• 2014

The statistical graphics is a design field focusing on the user perception aspects for the correct information delivery and the effective understanding, with the use of the quantitative data through the information analysis, extraction, visualization process. The statistical graphics with the big data composition factor is termed as the statistical big data graphics. In the statistical graphics the visual factors are used to reduce the errors in the perception part and to successfully deliver the information. However, in the statistical big data graphics the visual factors of the enormous data are causing the cognitive discouragements. The purpose of this study is to extract the cognitive discouragement factors from the big data statistical graphics, categorizing the types of the statistical big data graphics as 'network type', 'segment type', and 'mixed type', based on their compositional shapes, and explored the characteristics according to them. Especially, based on the visual main factors in the statistical big data graphics, We extracted the cognitive discouragement factors that appear in the high visualization as the four categories: 'multi-dimensional cases', 'various color', 'information overlap', and 'legibility of the writing'.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.26 no.2
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• pp.111-116
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• 2008

The study installed non metric camera which was a 10 Mega Pixel camera in RC Helicopter. And the study controlled images hotographed in air on land, considering their overlap. The study could express DEM by abstracting TIN from the acquired images through image registration. Also, the study compared and examined accuracy between reference point and check point observed by Total Station which was a conventional type of survey. As the results, the study could get errors of $-0.194{\sim}0.224\;m$ on X axis, $-0.088{\sim}0.180\;m$ on Y axis and $-0.286{\sim}0.285\;m$ on Z axis. Expressing an error's RMSE in the checkpoint, the study could get of 0.021388 m on X axis, 0.015285 m on Y axis and 0.041872 m on Z axis. It is judged that the above photographing and analyzing technique are better than the existing Total Station to acquire more terrain elevation data.

• Proceedings of the KSRS Conference
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• 2005.10a
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• pp.182-185
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• 2005

Satellite cameras are calibrated before launch in detail and in general, but it cannot be guaranteed that the geometry is not changing during launch and caused by thermal influence of the sun in the orbit. Modem satellite imaging systems are based on CCD-line sensors. Because of the required high sampling rate the length of used CCD-lines is limited. For reaching a sufficient swath width, some CCD-lines are combined to a longer virtual CCD-line. The images generated by the individual CCD-lines do overlap slightly and so they can be shifted in x- and y-direction in relation to a chosen reference image just based on tie points. For the alignment and difference in scale, control points are required. The resulting virtual image has only negligible errors in areas with very large difference in height caused by the difference in the location of the projection centers. Color images can be related to the joint panchromatic scenes just based on tie points. Pan-sharpened images may show only small color shifts in very mountainous areas and for moving objects. The direct sensor orientation has to be calibrated based on control points. Discrepancies in horizontal shift can only be separated from attitude discrepancies with a good three-dimensional control point distribution. For such a calibration a program based on geometric reconstruction of the sensor orientation is required. The approximations by 3D-affine transformation or direct linear transformation (DL n cannot be used. These methods do have also disadvantages for standard sensor orientation. The image orientation by geometric reconstruction can be improved by self calibration with additional parameters for the analysis and compensation of remaining systematic effects for example caused by a not linear CCD-line. The determined sensor geometry can be used for the generation? of rational polynomial coefficients, describing the sensor geometry by relations of polynomials of the ground coordinates X, Y and Z.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.20 no.8
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• pp.1431-1437
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• 2016

In mobile healthcare device, when to measure the heart rate by using the PPG signal, its performance is reduced according to the motion artifacts that is the movement of user. This is because the frequency range of motion (0.01-10 Hz) and that of PPG signals overlap. Also, the motion artifacts cannot be rectified by general filters. To solve the problem, this paper proposes a method using filter banks and independent component analysis (ICA). To evaluate the performance of the proposed method, we were artificially applied various movements and compared heart rate errors of the moving average filter and ICA. In the experimental results, heart rate error of the proposed method showed very low than moving average filter and ICA. In this way, it is possible to measure stable heart rate if the proposed method is applied to the healthcare terminal design.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2013.10a
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• pp.195-198
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• 2013

Recognition and Tracking of interesting object is the significant field in Computer Vision. Mean-Shift algorithm have chronic problems that some errors are occurred when histogram of tracking area is similar to another area. in this paper, we propose to solve the problem. Each algorithm blocks skin color filtering, face detect and Mean-Shift started consecutive order assists better operation of the next algorithm. Avoid to operations of the overhead of tracking area similar to a histogram distribution areas overlap only consider the number of white pixels by running the Viola-Jones algorithm, simple arithmetic increases the convergence of the Mean-Shift. The experimental results, it comes to 78% or more of white pixels in the Mean-Shift search area, only if the recognition of the face area when it is configured to perform a Viola-Jones algorithm is tracking the object, was 100 percent successful.

• Journal of the Korea Institute of Building Construction
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• v.11 no.5
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• pp.459-467
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• 2011

The work of constructing apartment housing involves various fields of industry that are linked to each other, and is based on a design document prepared by multiple technicians and architects. Consequently, design errors, material flaws or faulty construction works can cause defects, which sometimes overlap with each other. Construction companies should repair any defects found in a completed building within a specified period of time, and to do this, should establish a business plan by efficiently predicting the cost of defect repair. As it is very difficult for companies to accurately predict the occurrence of defects, historical performance data is used as a base. For domestic apartment housing units, data on the cost of defect repair is insufficient, so there are hardly any methods that can be used to make precise predictions. Therefore, the intent of this study is to develop a model that can predict the cost of defect repair by supply type and area, based on historical performance data with ten years worth of post-completion.

• Radiation Oncology Journal
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• v.25 no.2
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• pp.125-133
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• 2007

[ $\underline{Purpose}$ ]: This study was to design and fabricate a phantom for prostate cancer brachytherapy to validate a developed program applying a 3-film technique, and to compare it with the conventional 2-film technique for determining the location of an implanted seed. $\underline{Materials\;and\;Methods}$: The images were obtained from overlapped seeds by randomly placing a maximum of 63 seeds in the anterior-posterior (AP) position and at $-30^{\circ} to $30^{\circ} at $15^{\circ} intervals. Images obtained by use of the phantom were applied to the image processing procedure, and were then processed into the development program for seed localization. In this study, cases were set where one seed overlapped, where two seeds overlapped and where none of the three views resolved all seeds. The distance between the centers of each seed to the reference seed was calculated in a prescribed region. This distance determined the location of each seed in a given band. The location of the overlapped seeds was compared with that of the 2-film technique. $\underline{Results}$: With this program, the detection rate was 92.2% (at ${\pm}15^{\circ}), 94.1% (at ${\pm}30^{\circ}) and 70.6% (compared to the use of the 2-film technique). The overlaps were caused by one or more than two seeds that overlapped; the developed program can identify the location of each seed perfectly. However, for the third case the program was not able to resolve the overlap of the seeds. $\underline{Conclusion}$: This program can be used to improve treatment outcome for the brachytherapy of prostate cancer by reducing the number of errors in the process of reconstructing the locations of perfectly overlapped seeds.

• Korean Journal of Remote Sensing
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• v.34 no.6_1
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• pp.1143-1153
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• 2018

For TOPS InSAR processing, high-precision image co-registration is required. We propose an image co-registration method suitable for the TOPS mode by comparing the performance of cross correlation method, the geometric co-registration and the enhanced spectral diversity (ESD) matching algorithm based on the spectral diversity (SD) on the Sentinel-1 TOPS mode image. Using 23 pairs of interferometric pairs generated from 25 Sentinel-1 TOPS images, we applied the cross correlation (CC), geometric correction with only orbit information (GC1), geometric correction combined with iterative cross-correlation (GC2, GC3, GC4), and ESD iteration (ESD_GC, ESD_1, ESD_2). The mean of co-registration errors in azimuth direction by cross correlation and geometric matching are 0.0041 pixels and 0.0016 pixels, respectively. Although the ESD method shows the most accurate result with the error of less than 0.0005 pixels, the error of geometric co-registration is reduced to 0.001 pixels by repetition through additional cross correlation matching between the reference and resampled slave image. The ESD method is not applicable when the coherence of the burst overlap areas is low. Therefore, the geometric co-registration method through iterative processing is a suitable alternative for time series analysis using multiple SAR data or generating interferogram with long time intervals.