• Journal of Periodontal and Implant Science
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• 제28권1호
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• pp.177-185
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• 1998

치주염환자에서는 치아의 회전이나 순측경사등으로 인한 상악 정중부 이개 등의 심미적, 기능적 문제들이 자주 수반되어 후속 적인 교정치료를 요하는 경우가 많다. 이러한 경우 보조적인 교정치료로도 치료가 가능한데, 안정된 후방구치에서는 교정력을 가하지 않고 고정 원으로써 작용하게 하고 해당 치아만을 이동시켜야만 한다. 그러나 성인교정에서는 제한점들이 많기 때문에 비교정전문의에게는 섣불리 교정치료를 하기가 어렵다. 더구나 정확히 브라켓을 장착하는 것이 중요한데 간단한 문제는 아니다. Silverman등이 indirect bonding technique을 소개하면서 이런 문제점들을 해결하는데 도움을 주게 되었다. 그후 여러 사람 들에서 다양한 방법들이 소개되었지만 기본적인 원리는 구강 외에서 이상적인 위치에 브라켓을 위치시키고 tray를 이용해서 구강내 치아면에 재현하는 방법이다. 이런 방법을 이용함으로써 molar uprighting, forced eruption, 악교정술시 surgical arch wire 장착, 설측교정술 등에도 쉽게 적용할 수 있다. 이러한 관점에서, 비교정전문의들도 보다 쉽고, 정확하게 브라켓을 위치시킬 수 있는 indirect bonding technique를 이용한다면 보조적인 교정치료 뿐만 아니라 포괄적인 교정치료도 가능하리라 사료된다.

• Journal of Communications and Networks
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• 제13권6호
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• pp.664-677
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• 2011

In order to control interference and improve spectrum efficiency in the femtocell and macrocell overlaid system (FMOS), we propose a joint frequency bandwidth dynamic division, clustering and power control algorithm (JFCPA) for orthogonal-frequency-division-multiple access-based downlink FMOS. The overall system bandwidth is divided into three bands, and the macro-cellular coverage is divided into two areas according to the intensity of the interference from the macro base station to the femtocells, which are dynamically determined by using the JFCPA. A cluster is taken as the unit for frequency reuse among femtocells. We map the problem of clustering to the MAX k-CUT problem with the aim of eliminating the inter-femtocell collision interference, which is solved by a graph-based heuristic algorithm. Frequency bandwidth sharing or splitting between the femtocell tier and the macrocell tier is determined by a step-migration-algorithm-based power control. Simulations conducted to demonstrate the effectiveness of our proposed algorithm showed the frequency-reuse probability of the FMOS reuse band above 97.6% and at least 70% of the frequency bandwidth available for the macrocell tier, which means that the co-tier and the cross-tier interference were effectively controlled. Thus, high spectrum efficiency was achieved. The simulation results also clarified that the planning of frequency resource allocation in FMOS should take into account both the spatial density of femtocells and the interference suffered by them. Statistical results from our simulations also provide guidelines for actual FMOS planning.

• 한국동물위생학회지
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• 제30권3호
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• pp.445-457
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• 2007

This report studied the individual number, their favorite habitat, and change pattern of family and group number in Cheolwon Basin, starting in the early Oct. 2004 until late March. 2005 to investigate the ecological features of the Red-crowned Crane and the White-naped Crane. The Cranes arrived Cheolwon Basin in mid-October until next mid-March, and passed the winter in mid-November until next late-February The most visiting number amounted to 550 individuals and, that period was the most frosting mid-January to mid-February. The White-naped Crane visited Cheolwon Basin in autumn, the early winter and spring. Approximately, the wintering-number is 550 individuals, also, the mid-March was the peak-period of arrival and, the number amounted to 2,162 individuals. The cranes chose the farming area around mountains as their wintering habitat and were less likely to choose the farming area around lake as habitat. The Red-crowned Crane and the White-naped Crane showed the different periodical pattern in familial and group numbers. In case of the crane, the familial pattern was stable, but varied in grouping number, and this pattern was similar to the variation of overall individual number. And, also, the most grouping number was shown in the most freezing period of wintering period. The White-naped Crane showed the similar pattern of the Red-crowned Crane that is, stable family number and varying group number, this pattern affected the total number of entire individuals. Grouping number increased in migration period. Parasite infection rate is G japonensis 35.0%, G vipio 38.7%.

• BMB Reports
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• 제50권7호
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• pp.384-389
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• 2017

The Nogo-B receptor (NgBR) is necessary for not only Nogo-B-mediated angiogenesis but also vascular endothelial growth factor (VEGF) -induced angiogenesis. However, the molecular mechanisms underlying the regulatory role of the VEGF-NgBR axis in angiogenesis are not fully understood. Here, we report that miR-26a serves as a critical regulator of VEGF-mediated angiogenesis through directly targeting NgBR in endothelial cells (ECs). Stimulation of ECs by VEGF increased the expression of NgBR and decreased the expression of miR-26a. In addition, miR-26a decreased the VEGF-induced migration and proliferation of ECs. Moreover, miR-26a overexpression in ECs decreased the VEGF-induced phosphorylation of the endothelial nitric oxide synthase (eNOS) and the production of nitric oxide, which is important for angiogenesis. Overall, these data suggest that miR-26a plays a key role in VEGF-mediated angiogenesis through the modulation of eNOS activity, which is mediated by its ability to regulate NgBR expression by directly targeting the NgBR 3'-UTR.

• 지구물리와물리탐사
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• 제2권3호
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• pp.149-153
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• 1999

본 연구는 한국석유공사가 셸사(화란)와 공동탐사를 하고있는 남콘손분지에 대한 3차원 탐사작업의 일환으로 실시되었으며 구조가 매우 복잡한 동지역에서의 탄성파층서 해석 사례를 소개하고자 한다. 지질구조가 복잡한 지역에서는 탄성파상이나 시퀀스 경계면 형태(lap-out pattern)가 탄성파 자료상에 잘 나타나지 않으므로 Exxon Group(Vail et at., 1977)등이 개발한 탄성파 층서 분석법의 한계점이 있다. 이러한 지역에서는 시추공의 층서분석 결과와 탄성파 Attribute 및 등층후도 등을 이용하여 탄성파 층서 분석을 실시할 수 있다. 연구결과 탄성파 Attribute는 시퀀스 및 시스템트랙면의 고퇴적 환경과 암상변화와 대비가 되며 등층후도 및 구조도를 사용하여 시스템트랙 내부의 층서변화와 대비가 가능하였다. 또한 Azimuth Attribute를 사용하여 탄화수소의 이동경로 등을 예측할 수 있었다. 이러한 층서분석 결과를 종합하여 저류암, 덮개암, 구조형성시기, 및 탄화수소의 이동경로 등에 대한 리스크를 계산하는데 이용하였다.

• 생명과학회지
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• 제7권3호
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• pp.198-204
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• 1997

tyrosine 인산화효소계를 통한 신호전달은 신경의 발생과 연접환성조절에 중요한 역할을 한다. 흰쥐 소뇌의 연접후치밀질에 존재하는 tyrosine 함유 당백질들을 조사하기 위하여 immunoblot 분석을 한 결과, 소뇌 연접후치밀질의 전반적인 단백질조성은 전뇌와 비슷하였다. phosphotyrosine 특이성 항체로, immunobolot 한 결과 소뇌의 주된 tyrosine 인산화 단백질은 50 kD 크기의 새로운 단백질이었다. PSD-50로 명명한 이 단백질은 SDS-PAGE에서 $\alpha$CaMKII와 같은 위치에 이동하였다. 그러나 소뇌에는 전뇌에 비하여 적은량의 $\alpha$CaMKII가 존재함에도 불구하고 전뇌보다 더 강한 phosphotyrosine immunoblot signal을 보이는 것으로 보아 PSD-50는 아마도 $\alpha$CaMKII와는 다른 단백질로 추정된다.

• International Journal of Oral Biology
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• 제46권3호
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• pp.105-110
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• 2021

The physicochemical properties of crystalline titanium dioxide nanoparticles (TiO₂ NPs) were investigated by comparing amorphous (amTiO₂), anatase (aTiO₂), metaphase of anatase-rutile (arTiO₂), and rutile (rTiO₂) NPs, which were prepared at various calcination temperatures (100℃, 400℃, 600℃, and 900℃). X-ray diffraction (XRD) and scanning electron microscopy (SEM) analyses confirmed that the phase-transformed TiO₂ had the characteristic features of crystallinity and average size. The surface chemical properties of the crystalline phases were different in the spectral analysis. As anatase transformed to the rutile phase, the band of the hydroxyl group at 3,600-3,100 cm^-1 decreased gradually, as assessed using Fourier transform infrared spectroscopy (FT-IR). For ultraviolet-visible (UV-Vis) spectra, the maximum absorbance of anatase TiO₂ NPs at 309 nm was blue-shifted to 290 nm at the rutile phase with reduced absorbance. Under the electric field of capillary electrophoresis (CE), TiO₂ NPs in anatase migrated and detected as a broaden peak, whereas the rutile NPs did not. In addition, anatase showed the highest photocatalytic activity in an UV-irradiated dye degradation assay in the following order: aTiO₂ > arTiO₂ > rTiO₂. Overall, the phases of TiO₂ NPs showed characteristic physicochemical properties regarding size, surface chemical properties, UV absorbance, CE migration, and photocatalytic activity.

• 한국의상디자인학회지
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• 제21권3호
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• pp.1-11
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• 2019

This study examined the cause of the phenomenon of shrinkage in machine-embroidered fabrics, specifically those made of thin and pliable fabrics. Four woven fabrics and two knitted fabrics were selected as samples for analysis. The fabrics selected were silk organza, flax linen, polyester chiffon, cotton batiste, polyester raschel mesh, and cotton jersey. The thickness and drapability of the fabrics were observed and the shrinkage of the various types of embroidered fabrics produced using satin & step stitch techniques were measured. Moreover, the correlation between the shrinkage of the machine-embroidered fabrics and the drapability of the original fabrics was analyzed. Also, the colorfastness of six embroidery yarns was determined. The results of the study are as follows: first, the shrinkage of machine-embroidered fabrics increased at a greater rate than in embroidered knitted fabrics as compared to rates in embroidered woven fabrics. Moreover, in terms of stitch techniques, there was a greater shrinkage rate when satin stitch was applied compared to step stitch. Second, the shrinkage rate of machine-embroidered fabrics decreased when a stabilizer was fused onto the fabric. The shrinkage rate also decreased for fabrics when fused with paper stabilizer compared to those without it, and the rate decreased at a greater amount with paper stabilizer as compared to alginate film. Third, since there was a strong correlation between the shrinkage rate of the embroidered fabric and the drapability ratio of the original fabric, it was generally the case that the more pliable the fabric was, the greater the shrinkage rate was when the fabric was embroidered. Fourth, while the embroidery yarns mainly used in machine-embroidery presented an overall excellent level of colorfastness, there was slight color migration of level 4 to level 5 when using viscose rayon.

• Biomolecules & Therapeutics
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• 제27권2호
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• pp.216-221
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• 2019

The c-Met protein is a receptor tyrosine kinase involved in cell growth, proliferation, survival, and angiogenesis of several human tumors. Overexpression of c-Met has been found in gastric cancers and correlated with a poor prognosis. Indirubin is the active component of Danggui Longhui Wan, which is a traditional Chinese antileukemic recipe. In the present study, we tested the anti-cancer effects of an indirubin derivative, LDD-1937, on human gastric cancer cells SNU-638. When we performed the in vitro kinase assay against the c-Met activity, LDD-1937 inhibited the activity of c-Met. This result was confirmed by immunoblot and immunofluorescence of phosphorylated c-Met. Immunoblot analysis showed that LDD-1937 decreased the expression of the Erk1/2, STAT3, STAT5, and Akt, downstream proteins of c-Met. In addition, LDD-1937 reduced the cell viability and suppressed colony formation and migration of SNU-638 cells. Furthermore, LDD-1937 induced $G_2/M$ phase arrest in the SNU-638 cells by decreasing the expression levels of cyclin B1 and CDC2. Cleaved-PARP, an apoptosis-related protein, was up-regulated in cells treated with LDD-1937. Overall, this study suggests that LDD-1937 may be a novel small-molecule with therapeutic potential for selectively inhibiting c-Met and c-Met downstream pathways in human gastric cancers overexpressing c-Met.

• 한국환경과학회지
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• 제30권12호
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• pp.1067-1079
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• 2021

The coastal water is a space where salmon (Oncorhynchus keta), critical energy-conveying mediator, stay to adapt to different environments while traveling between ocean and river ecosystems for spawning and growth. The mid-eastern coast of Korea (MECW) is the southern limit of salmon distributed in the North Pacific Ocean. Understanding the distribution and migration characteristics of salmon in the MECW is important for the prediction of changes in the amount and distribution of salmon related to changes in the future marine environment. We analyzed the relationship between the salmon migratory timing ascending the Wangpi river and change in vertical seawater temperature and tidal elevation. Overall results highlight that (1) Salmon began to ascend the river when the sea surface water temperature (SST) decreased below 20℃; (2) The number of salmon ascending the river increased when the temperature difference between the upper and lower layers decreased, but decreased when the temperature difference was higher than 5℃; (3) The number of salmon ascending the river peaked, when the SST was 18℃-19℃ and sea levels rose at high tide. This study provide important insight into predicting changes in the ecosystem energy circulation through climate change at its southern distribution limit.