• Journal of Bio-Environment Control
• /
• v.19 no.4
• /
• pp.311-316
• /
• 2010

This study was conducted to investigate the effect of anaerobic fermentation of wheat bran to prevent root-knot nematodes which are infected in plastic house due to over 10 years continuous cultivation of fruits and vegetables. Anaerobic fermentation treatment of wheat bran was done for 20 days by mixture of 2,000 kg fresh wheat bran per 10 are and soil with water in 30 cm soil depth. Chemical treatment of fosthiazate was done by mixture of 6 kg soil for 7 days. Both treatments show suppression of density of rootknot nematodes, especially in anaerobic fermentation treatment. Anaerobic fermentation treatment keeps the low level of root-knot nematode density until 90 days of cultivation and also showed good effect of melon growth. Related with death percentage of melon plant, anaerobic fermentation treatment shows only 3% and also large size of quality fruit but control 65%. Anaerobic fermentation treatment of wheat bran have proved to control the level of root-knot nematodes instead of synthetic chemicals for at least one cropping season and it showed good effect to fruit quality.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.17
• /
• pp.7485-7489
• /
• 2015

Background: Breast cancer is the most common type of cancer in women throughout the world. However, in comparison with Western women, it presents relatively early in women of Asian ethnicity. Early menarche, late menopause, use of OCP's, family history of benign or malignant breast disease, exposure to radiation and BMI in the under-weight range are well known risk factors for the development of breast cancer in premenopausal women. Early detection with the use of breast self-examination (BSE) and breast cancer screening programs can lead to a reduction in the mortality rates due to breast cancer. The aim of our study was to assess the risk factors for breast cancer among young women and to emphasize the importance of early screening among them. Materials and Methods: We conducted a cross-sectional study among women aged 18 to 25 using a self-administered questionnaire. Data was collected over a period of 6 months from June to December, 2014. A total of 300 young women selected randomly from Dow Medical College and various departments of Karachi University successfully completed the survey. Results: Respondents were 18-25 years of age (mean age=21.5). Out of the 300 young females, 90 (30%) had at least one risk factor, 90 (30%) had two, 40 (13%) had three, 8 (2.7%) had four, 2 (0.7%) had five while one female was found to have six positive risk factors for breast cancer. Some 66 women (22%) experienced symptoms of breast cancer such as non-cyclical pain and lumps. While 222 women (74%) had never performed breast self-examination, 22 (7.3%) had had a breast examination done by a health professional while 32 (10.7%) had participated in breast screening programs. A total of 223 (74.3%) women considered breast cancer screening important for young women. Conclusions: The percentage of young women with risk factors for breast cancer was found to be alarmingly high. Therefore, screening for breast cancer should start at an early age especially in high risk groups. Awareness about breast self-examination should be emphasized. Moreover, screening programs should be started to ensure early detection and reduction of mortality rates caused by breast cancer also in young Pakistani females.

• Journal of Korean Society of Forest Science
• /
• v.101 no.4
• /
• pp.579-591
• /
• 2012

Berchemia berchemiaefolia is a rare and endangered species and important as a honey resource. The purposes of this study were to investigate physical environmental factors and the population and community structure of Berchemia berchemiaefolia stands at Mt. Gunja in Sogrisan National Park in Chungcheongbuk-do. The B. berchemiaefolia stands belonged to deciduous forests in mid-temperate zone and were $5{\sim}25^{\circ}$ in slope, 30~90% in rock ratio, and 6.37 in soil pH. They had 656 trees within the area of 36 ha and their average density was 18.2 trees per ha. The trees within the stands were 11.8 m in tree height, 22.6 cm in DBH and 56 years old. The number of branched stems was the maximum 8 and 32.9% of the trees were branched. B. berchemiaefolia trees over 12 cm diameter occupied 89.9%, but young B. berchemiaefolia did only 11%. The structure of B. berchemiaefolia stands were classified into three groups as Acer pseudo-sieboldianum & A. mono community group, A. pseudo-sieboldianum & Quercus aliena community group, and B. berchemiaefolia & Quercus serata community group. The mean importance value of B. berchemiaefolia was 10.9%, while species diversity of the community ranged 0.77~1.31 and interspecific competition ranged 0.78~0.94. The dominance of the community ranged of 0.07~0.29 and the evenness ranged 0.71~0.93. Although B. berchemiaefolia was dominant in the habitat, but the species was already in natural successional stage to Cornus controversa or Ulmus davidiana var. japonica.

• The Journal of the Acoustical Society of Korea
• /
• v.37 no.5
• /
• pp.369-377
• /
• 2018

This study investigated the effect of noise and reverberation on subjective measure of speech transmission performance for elderly person with hearing loss in residential space through listening test. Floor impact, road traffic, airborne, and drainage noise were employed as the residential noise, and several impulse responses were obtained through room acoustical computer simulation for an apartment building. Sound sources for the listening test consisted of residential noises and speech sounds for boh the young (the original sound) and the aged (the sound filtered out by filters with frequency responses of hearing loss of 65 years elderly person). In the listening test, subjects evaluated speech intelligibility and listening difficulty for the presented word ($L_{Aeq}$ 55 dB) at three noise levels ($L_{Aeq}$ 30, 40, 50 dB) and three reverberation times (0.5, 1.0, 1.5 s). Results showed that the residential space with noise level lower than equal to 50 dB ($L_{i,Fmax,AW}$) for jumping noise and 40 dB ($L_{Aeq}$) for road traffic, airborne, and drainage noise had speech intelligibility of 90 % and over and listening difficulty of 30 % and below. Speech intelligibility and listening difficulty for the aged sound source was shown to be 0 % ~ 5 % lower and 2 % ~ 20 % higher than those for the young sound source, respectively.

• Journal of Bio-Environment Control
• /
• v.26 no.2
• /
• pp.64-71
• /
• 2017

The study was performed on the effects of crop load of pear (Pyrus pyrifolia Nakai) trees on shoot growth, reserved nutrients, and fruit production for two years, as well as regrowth of cuttings treated with various cold temperatures in 2012 and 2013. Crop load adjustments included three levels of fruiting; 54 (60%), 90 (100%), and 126 fruits per tree (140%). As increasing crop load from 60% to 140%, water sprout growth decreased, and one-year old shoot resulted in declined concentrations of total carbon, macro-nutrients, and free sugar. The 140% of crop load greatly increased fruit yield of approximately 35 tons per ha in both 2011 and 2012 but slightly reduced weight, size, and soluble solid contents in fruit. However, 140% of crop load increased annual production income to approximately over 10 million won compared to the 60% and 100% of crop load. Germination rates in the cuttings did not rapidly decrease up to $-20^{\circ}C$ in a growth chamber condition. The 140% of crop load decreased germination rates less than 70% of cuttings grown under $-30^{\circ}C$. Amounts of electrolyte leakage in the cuttings under various cold temperatures were not significantly different among the adjustment of crop load.

• Korean Journal of Psychosomatic Medicine
• /
• v.21 no.2
• /
• pp.140-146
• /
• 2013

Objectives: We compared the characteristics of the pain threshold and pain experience between demented group and non-demented group. Methods: This study was part of Gangwon projects for early detection of dementia in 2010. We recruited 8302 local resident ages over 65 years old. Of theses, 1259 people who scored low MMSE were selected and 365 of them completed CERAD-K(Consortium to Establish a Registry for Alzheimer's disease). Finally, 90 in non-demented group and 57 in demented group(mild to moderate Alzheimer's disease) were analyzed. Pain threshold was experimentally measured by pressure algometer and we investigated the pain experience, by Brief pain inventory (BPI), a self-report test. Results: In the demographic characteristics, there are more female, higher ages, lower education in the demented group. There was no significant difference between the two groups in the pain threshold. On the BPI results, 'shoulder pain', 'the number of pain' and 'interference of working' were significantly more prevalent in non-demented group. However, there are no significant differences between the groups in the 'pain severity', 'prevalence of pain' and 'pain treatment'. Conclusions: Demented group report less pain experience but, still perceived pain. It support previous studies that patient with dementia have increased pain tolerance but preserved pain threshold. Thus, active pain assessment and treatment for patients with dementia is needed.

• Journal of Pharmaceutical Investigation
• /
• v.36 no.1
• /
• pp.67-73
• /
• 2006

Lornoxicam is a nonsteroidal anti-inflammatory drug that decreases prostaglandin synthesis by inhibiting cyclooxygenase. It has analgesic, antipyretic and antiinflammatory effects. The purpose of the present study was to evaluate the bioequivalence of two lornoxicam tablets, $Xefo^{\circledR}$ (Hyundai Pharmaceutical Ind. Co., Ltd.) and Lornocam (Samchundang Pharmaceutical Co., Ltd.), according to the guidelines of the Korea Food and Drug Administration (KFDA). The release of lornoxicam from the two lornoxicam formulations in vitro was tested using KP VIII Apparatus II method with various dissolution media (pH 1.2, 4.0, 6.8 buffer solution and water). Twenty eight healthy male subjects, $24.39{\pm}1.95$ years in age and $68.63{\pm}7.25$ kg in body weight, were divided into two groups and a randomized $2\;{\time}\;2$ cross-over study was employed. After a single tablet containing 4 mg as lornoxicam was orally administered, blood samples were taken at predetermined time intervals and the concentrations of lornoxicam in serum were determined using HPLC with UV detector. The dissolution profiles of two formulations were similar in all tested dissolution media. The pharmacokinetic parameters such as $AUC_t,\;C_{max}\;and\;T_{max}$ were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed $AUC_t,\;C_{max}$ and untransformed $T_{max}$. The results showed that the differences between two formulations based on the reference drug, $Xefo^{\circledR},$ were -1.56%, 2.16% and -17.12% for $AUC_t,\;C_{max}\;and\;T_{max},$ respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log 0.8 to log 1.25 (e.g., $log\;0.90{\sim}log\;1.05$ and $log\; 0.88{\sim}log\;1.17$ for $AUC_t\;and\;C_{max},$ respectively). Thus, the criteria of the KFDA bioequivalence guideline were satisfied, indicating Lornocam tablet was bioequivalent to $Xefo^{\circledR}$ tablet.

• Korean Journal of Food Science and Technology
• /
• v.35 no.6
• /
• pp.1155-1161
• /
• 2003

A three-year (2000-2002) survey on consumer's awareness and perception of genetically-modified (GM) foods was conducted on random samples of Korean consumers. More than 65% of the respondents were exposed to some information related to GM foods. The greatest benefit of the development of GM foods was thought to be their remedy of potential food shortages in the future. More than 90% of Korean consumers wanted GM foods to be labeled. About 18% of the respondents would buy GM foods voluntarily, whereas over 46% would not until they knew more about the product. Only 39% of Korean consumers were found to have realized that food items origination from plants contained genes. More consumers responded that they would not buy herbicide-resistant GM soybean and buy vitamin-enriched GM soybean instead. Many Korean consumers appeared to make decisions of acceptance or rejection of GM foods not on the basis of biotechnology, but on the basis of the word(s) used to describe the products, such as herbicide and vitamin. Only 4% of Korean consumers responded that GM foods were the greatest threat to the safety of Korean foods.

• Korean Journal of Agricultural and Forest Meteorology
• /
• v.10 no.2
• /
• pp.65-68
• /
• 2008

Crop production in a country is very crucial not only in a country's crop self-sufficiency, but also in carbon recycle. Crop can capture and store the emitted $CO_2$ by cereal food consumption. However, imported cereal food is not concerned in carbon recycle and this hinders the accurate estimation of carbon recycle. Korea imports major grain products including wheat, corn, soybean, and rice and about 90% of the grain composition consists of carbohydrate, protein and lipid. Carbon portions in carbohydrate, protein and lipid are 45, 53, and 77%, respectively. When the carbon portions are digested and converted into $CO_2$ completely, one ton of rice, wheat, corn, and soybean can release 1.51, 1.63, 1.56, and 1.56 tons of $CO_2$ to the atmopshere, respectively. Based on this premise, the evolved $CO_2$ calculated from imported grains for the last 4 years in Korea was over 21 MT of $CO_2$. This amount is equivalent to 4.8 billion US dollars in the conception of carbon tax. These results suggest that a decrease in a cereal import(i.e, an increase in a country's crop self-sufficiency) can lower $CO_2$ release to the atmosphere.

• Journal of Pharmaceutical Investigation
• /
• v.30 no.1
• /
• pp.61-65
• /
• 2000

Doxazosin, a postsynaptic selective ${\alpha}1-adrenoceptor$ antagonist, is a potent antihypertensive agent which reduces peripheral resistance and blood pressure by vasodilatation of peripheral vessels. It is also used in the treatment of urinary obstruction by benign prostatic hypertrophy. The purpose of the present study was to evaluate the bioequivalence of two doxazosin tablets, $Cardura^{TM}$ (Pfizer Korea Ltd.) and $Cardil^{TM};$ (Kyungdong Pharmaceutical Co., Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). Sixteen normal male volunteers, $24.19{\pm}2.48$ years in age and $62.41{\pm}6.66$ kg in body weight, were divided into two groups and a randomized $2{\times}2$ cross-over study was employed. After one tablet containing 2 mg of doxazosin was orally administered, blood was taken at predetermined time intervals and the concentrations of doxazosin in serum were determined with an HPLC method using spectrofluorometric detector. Pharmacokinetic parameters such as $AUC_t,\;C_{max}\;and\;T_{max}$ were calculated and ANOVA test was utilized for the statistical analysis of the parameters. The results showed that the differences in $AUC_t,\;C_{max}\;and\;T_{max}$ between two tablets were -1.54%, -1.51 % and 3.42%, respectively, when calculated against the $Cardura^{TM}$ tablet. The powers $(1-{\beta})$ for $AUC_t,\;C_{max}\;and\;T_{max}$ were all more than 99.00%. Minimum detectable differences $(\Delta)$ at ${\alpha}=0.05\;and\;1-{\beta}=0.8$ were all less than 20% (e.g., 12.73%, 12.84% and 13.01% for $AUC_t,\;C_{max}\;and\;T_{max}$, respectively). The 90% confidence intervals were all within :${\pm}20%$ (e.g., $-8.97{\sim}5.90,\;-9.01{\sim}6.00\;and\;-4.16{\sim}11.05\;for\;AUC_t,\;C_{max}\;and\;T_{max},\;respectively)$. All of the above para- meters met the criteria of KFDA for bioequivalence, indicating that $Cardil^{TM}$ tablet is bioequivalent to $Cardura^{TM}$ tablet.