• Journal of Pharmacopuncture
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• v.3 no.2
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• pp.1-25
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• 2000

We were trying to study the validity of Puffer fish's poison(Tetrodotoxin- TTX) to make a traditional Korean Medical treatment. The following conclusions were made after literary studies. 1. The first record of the puffer fish dates back 2000 years ago in the Chinese text Book of Mountain and Sea and other texts from the similar period. 2. Puffer fish's poison IS known as tetrodotoxin which is an amino perhydroquinazoline compound. It has a chemical formula of $C_{11}H_{17}N_3O_8$ in the hemiacetal structure and has the molecular weight of 319. 3. Tetrodotoxin (TTX) plays a role as potent neurotransmitter blocker by blocking the $Na^+$ -gate channel which hinders the influx of $Na^+$ ion into the cell. 4. Symptoms of the puffer fish poisoning ranges from blunted sense in the lips and tongue, occasional vomiting in the first degree to sudden descending of the blood pressure, apnea, and other critical conditions in the fourth degree. Intoxication of the puffer fish poison progresses at a rapid pace as death may occur after an hour and half up to eight hours in maximum. Typical death occurs after four to six hours. 5. Ways to treat the puffer fish poisoning include gastric irrigation, induce vomiting, purgation, intravenous fluid injection, and correcting electrolytic imbalance and acidosis. In cases of dyspnea, apply oxygen inhalation and conduct artificial respiration. 6. Tetrodotoxin (TTX) may be applied in treating brain disorders, ocular pain, excess pain in the large intestine and ileum, and relieving tension of the skeletal museles, neuralgia, rheumatism, arthritis, and etc. 7. In terms of Oriental medicine, the puffer fish poison has characteristics of sweet, warm, and poisonous. It's known efficacies are to tonify weakness, dispel damp, benefit the lower back, relieve hemorrhoid, kills parasites, remove edema, and so forth. And the puffer fish eggs processed with ginger are said to be effective against tuberculosis and lung cancer, thus, it's validity must be investigated and further research should be followed.

• The Journal of Internal Korean Medicine
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• v.21 no.2
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• pp.341-348
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• 2000

I have treated one ischemic stroke patient in acute stage with Seonghyangjeonggi-san, and observed remarkable reduction of the size ischemic portion in brain CT, notable improved motor power of patient. So I report this case of stroke patint. The ischemic penumbra, simply stated, is the part of the brain that is sandwiched brain regions committed to die and those that receive enough blood to communicate. Therefore, it is ischemic brain tissue that has just enough to communicte and function. The life expectancy of the penumbrais short. Although the penumbra is an elegant concept, in practice, it has been a difficult one to exploit. Up to now, a lot of research worker have tried to develop the method to make a accurate diagnosis. and then we know that PET and Xenon CT is available for the diagnosis for the ischemic penumbra. But those are not perfect to diagnose of penumbra. The case in my case report was confirmed as ischemic penumbra with CT. I know that CT is not prefect to diagnose penumbra, but I just want to raise the interest in penumbra of oriental medicine researcher and my report will be benificial to the penumbra researcher.

• The Journal of Pediatrics of Korean Medicine
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• v.26 no.2
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• pp.53-61
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• 2012

Objectives To make comprehensive feature of clinical trials using herbal medicine and their results by today, then help a strategy for herbal medication-derived clinical studies in the future. Methods Through medical website (Pubmed EBSCO Medline), foreign clinical literatures about atopic dermatitis and herbal medicine were searched. And domestic clinical literatures about atopic dermatitis using internet website (OASIS) and hand-searching. Analysis was performed according to distribution mainly by subject, study design, number by year and its efficacy. Results and Conclusions Seventy-nine (Domestic literatures: Fifty, Foreign literatures: Twenty-nine) literatures were selected according to inclusion criteria of clinical study. 80% of domestic clinical literatures were observational studies, 50% of foreign were intervention. There were six adverse effect case studies, two follow-ups, one case report, four translational and four uncontrolled clinical trials in foreign literatures. And nineteen case reports, eighteen case series, two follow-up and five uncontrolled clinical studies in domestic. Six RCTs have established by four external herb therapy and two decoctions in Korea, showed positive effects. Three out of four external applications RCTs, four out of seven decoctions showed positive results in foreign studies. This study revealed the current status of atopic dermatitis clinical research using herbal drugs. To put clinical trials to use of herbal medicine in the treatment atopic dermatitis, scientific and objective-based studies should be needed.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.9 no.1
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• pp.23-46
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• 2005

Background and purpose: Maek Kyoung(脈經) is a book written, compiled, and edited by Wang Hui circa 3 A.D. This book is the first technical book devoted to the diagnostics. These are very important data but never make a special study and translate. so I hope this treatise can be great help to understand diagnosis study. Methods: Maek Kyoung(脈經) consists of ten volumes, and the third volume consists of the five chapters, including inter-generation and inter-restriction of the five viscera and the six entrails and prognosis of diseases. This treatise is made up of principal, notes, study and conclusion, we tried to make a translation faithful to the original. Results and Conclusion: Chapter 3 refers to five things. The first is relation between spleen and stomach, the second is how to diagnose diseases by using intergneration and inter-restriction of five elements, the third is roles of spleen that has an influence on four viscera through four seasons, the forth is the fact that quantity of gastroqi decides prognosis of diseases, and the fifth is that climate change has influence on the seriousness of diseases. Chapter 4 refers to four things. The first is relation between lung and large intestines, the second is ordinary and extraordinary pulse condition of lung, the third is that pulse condition including its speed, and the forth is how to diagnose diseases by using intergneration and inter-restriction of five elements and climate change.

• Journal of Acupuncture Research
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• v.17 no.3
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• pp.233-249
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• 2000

Objectives : Gimun-chimbub(Jimen-zhenfa) is the method of needling which is based on Gimun-hak (Jimen-xue), and it is the most excellent method of needling than any other methods. In spite of the superiority of Gimun-chimbub(Jimen-zhenfa), there are few documents which explain it in details. The purpose of this study is to make clear principle of Gimun(Jimen) & apptication of Gimun-chimbub(Jimen-zhenfa) so many clinicians can make good use of it. Methods : Through investigation of many documents concerning Gimun(Jimen), Gimun-chimbub(Jimen-zhenfa) and Bosa(buxie), the author first explained principle of Gimun(Jimen) and then made clear how to apply it in needling and how to perform Bosa(buxie). Conclusions : 1. Gimun-hak(Jimen-xue) is constituted combinations of infinite change of Chen-Gy-In Samje(Tianrendi Sancai) and Hado lakse(Hetu Luoshu). Gimun-hak(Jimen-xue), is the study which shows us the change of space time e- ntangling at once, and it is applied to troublous times and critical situations. Gimun-chimbub(Jimen-zhenfa) combines of the method of needling with the time when Chen(Tian) opens and closes. So according to each cases, doctor must consider the adequate time. For example, in case of acute disease, the first day when the patient got ill is ta - ken. In case of chronic disease, the day when the patient came to see a doctor is taken. In Gimun-chimbub(Jimen-zhenfa), first it uses Jik-Sa-Mun(zhishimen) which can ac - cept Chen-Gi(tianqi). When needling, doctor must find the accurate acu-points and perform Bosa(buxie). Finally it uses Saeng-Mun(shengmen) which stirs up the vit - ality. Using Saeng-Mun(shengmen) decreases the rate of relapse of diseases.

• The Journal of Korean Obstetrics and Gynecology
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• v.21 no.4
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• pp.193-206
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• 2008

Purpose: In spite of many arguments on the result of WHI (Women's Health Initiative) study, no one can deny the necessity for researches on the alternative treatment to HRT (hormone replacement therapy). In this study, the author wanted to investigate the method of precedent acupuncture RCTs (randomized controlled trials) to make out the appropriate acupuncture study design on postmenopausal and perimenopausal hot flashes in Korea. Methods: Precedent studies were investigated using Pubmed search and key-words "acupuncture and hot flash", "acupuncture and menopause", "acupuncture and vasomotor", limited to RCT, from 2000 to 2008 April. Results: As a result. 10 studies were searched. In the hereafter studies, multi-center clinical trials which consist of population group of postmenopausal and perimenopausal women that would be pre-stratified and more than 50 patients per treatment arm seem adequate. Sham control study can make out the proper consequence because many people are get used to acupuncture in Korea. Flexible choice of acupoints addressed an individual's symptoms using standardized algorithm is recommended. Treatment consist of 4 weeks' observation, 11 acupuncture sessions during 7 weeks, follow-up of 3 months or more after treatment and hot flash score as a primary outcome measure seem appropriate. After all, higher level of description according to global standard must be obtained in the study report and publishing. Conclusion: The researchers should develope the methodology of acupuncture clinical trial on the postmenopausal and perimenopausal hot flashes.

• Korean Journal of Acupuncture
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• v.28 no.3
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• pp.151-163
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• 2011

Objectives : Our aim is to evaluate feasibility for massive clinical research and to make basic analysis of efficacy and safety of acupuncture treatment for chronic fatigue syndrome and idiopathic chronic fatigue. Methods : This study is a protocol for a pilot randomized controlled trial. It was developed through literature searches and discussions among researchers. Results : Forty participants allocated to acupuncture group and wait-list group. Participants allocated to acupuncture group will be treated three times per week for a total of 12 sessions over four weeks. Eight points (GV20; bilatral GB20, BL11, BL13, BL15, BL18, BL20, BL23) have been selected for the acupuncture group. Participants in the wait-list group will not receive acupuncture treatment during study period and follow-up will be made in the 5th and 9th weeks after random allocation. Then the same acupuncture treatment as that performed to the acupuncture group will be made to the wait-list group. Fatigue Severity Scale, a short form of Stress Response Inventory, Beck Depression Inventory, and Insomnia Severity Index will be used as outcome variables to evaluate the efficacy of acupuncture. Safety will be assessed at every visit. Conclusions : The trial based on this study will be performed. The results of the trial will provide basis for the efficacy and safety of acupuncture treatment for chronic fatigue syndrome and idiopathic chronic fatigue.

• Journal of Korean Medical classics
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• v.23 no.2
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• pp.125-139
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• 2010

The character 'yeong(營)' has been used mixed with 'yeong(榮)' from the time of "Hwangjenaegyeong(黃帝內經)" up to now. One word can have a various meaning according to the context. So it is difficult to make a precise definition. Moreover as the words in Korean medicine are abstruse, it is necessary to classify and make the meaning straight with the words like 'yeong(營)' and 'yeong(榮)'. This study is focused on classifying the meanings and examples of 'yeong(營)' and 'yeong(榮)' by the dictionary definition, examples in medical classics, examples in "Hwangjenaegyeong(黃帝內經)". From this study, we get to know 'yeong(營)' and 'yeong(榮)' was used mixed with the concept of 'yeong-gi(營氣)' which means 'transporting nutrition'. The conclusion of this study is, from the dictionary definition and the aspect of oriental medicine physiology, using 'yeong(營)' is more reasonable than 'yeong(榮)' in both cases.

• The Korean Journal of Health Service Management
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• v.3 no.1
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• pp.78-90
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• 2009

The purpose of this study is to propose ways of promoting medical tourism in Busan. For the purpose, this researcher made a questionnaire survey of Japanese tourists who used in Busan International Ferry Terminal between January and April 30, 2008. Findings of the study can be summarized as follows. 86.3% of all respondents had never experienced any medical service in Korea. 57.3% said that the most important thing is the level of medical technology. Most of respondents preferred massage treatment using spa and sea water, followed by Oriental medical services. To make medical conditions(price competitiveness, high-level medical technology, high-quality medical facilities) of Busan properly informed to the outside, it is required to make the city itself more internationally recognized through public relations and strengthening individual medical services provided in the city. It is also required to build up a non-stop service system that helps foreign tourists not only easily use medical institutions, but also better cope with a variety of problems that they might face during stay in the city. To be more trustable to foreign patients, medical services of Busan should be certified by JCI. Furthermore, it is very much needed to develop products which connect medicine with tourism, for example, such programs that combine medical services, tourism, recreation and leisure.

• The Korea Journal of Herbology
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• v.21 no.2
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• pp.109-119
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• 2006

Objectives : This study was performed to approach of properties-flavours theory and the study of morphological standard in CORNI FRUCTUS. Methods : The properties-flavours theory were attempted with bibliographic method and various climate-information. The external-internal morphological standards were determined by using stereoscope and butanol series. Results and conclusion : 1. The significant analysis for the corni fructus as the properties-flavours theory, is a follow-up survey of the effect written in the official oriental medicine book. 2. The other analytic methods according to the gathering time, processing or storing system or especially nature or growth environment(altitude, temperature,. the mean moisture, and the agronomical survey) by way of the explanation of properties-flavours theory appears so many insufficiency at the many cases. 3. The external and internal characteristics according to the shape of original plant or herbal states, entirely correspond to all the literature on this subject. 4. According to the place of production, there are some different points. (l) In the external shapes, it is reasonable that if we make the basic standard of classification by the sharpness of color, the existence of gloss and the size of products. In the case of the Korean products, it shows bright and glossy color totally, but in the case of North Korea products, it shows black and lackluster. And in the case of the foreign products, it has softer body than Korea one and shows white color on the surface. (2) In the internal shapes, the Korea products has a thicker cuticle layer than the foreign one, and has fewer ca-oxalate in the parenchyma cell.