• 대한한방부인과학회지
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• 제18권4호
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• pp.136-143
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• 2005

Purpose : This study was performed to find differerces between postmenopausal and premenopausal women on HRV and DITI. Methods : 26 postmenopausal women(mean age${\pm}$SD, 50.96${\pm}$2.75) and 26 premenopausal women (mean age${\pm}$SD, 49.46${\pm}$3.33) were compared with HRV which was conducted in the sitting position for 5 minutes. Temperature of specific acupoints-Indang, Chonjung(CV17), Kwanwon(CV4) was checked using DITI image and obtained ${\Delta}T1$(Chonjung-Kwanwon), ${\Delta}T2$(Indang-Kwanwon), T0(Kwanwon) value in each group. Results : HRV measurements generally decreased in postmenopausal group than premenopausal group but there was no significance. ${\Delta}T1$ increased significantly in postmenopausal group compared with premenopausal group. ${\Delta}T2$ also increased in postmenopausal group but there was no significance. Conclusion : It can be suggested that Chonjung(CV17) can be the useful point to evaluate postmenopausal women by using DITI.

• 사상체질의학회지
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• 제26권4호
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• pp.400-408
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• 2014

Objectives The aim of this study was to report the improvement of delirium and performance status in the small-cell lung cancer patient who had multiple brain metastases and pericardial effusion after Sasang constitutional treatment. Methods We retrospectively reviewed the medical records, medical laboratory and image scans of 71-year-old male patient diagnosed as small-cell lung cancer. Results The small-cell lung cancer with multiple brain metastases patient sometimes talked deliriously even after the whole brain radiation therapy. During the hospitalization period, he showed delirium. We treated him with Gihwangbaekho-tang and Dojeokgangki-tang as a main therapy. After treatment, he didn't show delirium and performance status was improved. Conclusions A small-cell lung cancer with multiple brain metastases patient showed the improvement of symptoms (delirium, poor performance status, constipation and poor oral intake) with the treatment of Gihwangbaekho-tang, Yanggyuksanhwa-tang and Dojeokgangki-tang.

• 대한의용생체공학회:의공학회지
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• 제32권2호
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• pp.127-133
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• 2011

Arteria radialis is a branch of the brachial artery extending down the forearm around the wrist where it closes to skin surface. In the oriental medicine, the skin above arteria radialis has an important role because oriental medicine practitioners put their finger tips on the area, and diagnose patient's health conditions by feeling the pulsation of the arterial contraction. The finger tip diagnostic method relies on subjective decision of the practitioner; and there is a need to develop an objective diagnostic modality. The pulsation of the arterial contraction appears not only a movement on the site but also as temperature fluctuation due to pulsatile feeding of warmer blood. The goal of this study is to demonstrate a feasibility of using an infrared camera quantitatively to detect the temperature fluctuation on the skin. Clinical important three different areas, called chon, gwan, chuk, near a wrist where the arteria radialis reaches close to skin surface are marked with small pieces of surgical tape. A high-speed and high-resolution infrared camera with a 3 cm of field of view measures these areas for 10 second at 200 frames per second with a 320*240 pixel size. The pulsatile temperature fluctuation is calculated after passing a band pass filter to remove any stationary temperature over 10 second. The temperature fluctuation of a healthy male volunteer is measured at a room temperature as a control, and is compared with another measurement performed after 20 minutes staying in a room at a 40 degree Celsius. This comparison is repeated for three times, and indicates that the fluctuation increases after staying 20 minutes in the warm room. This increase becomes smaller when the person stays in the warm room with an acupuncture treatment that decreases body temperature. So that an objective diagnostics on the site may become feasible.

• 동의생리병리학회지
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• 제35권6호
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• pp.267-273
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• 2021

Mibyeong (sub-health) is a concept that represents the sub-health in traditional East Asian medicine. Assuming that the nose sizes and shapes are related to respiratory function, in this study, we hypothesized that the nose size and shape features are related to the self-rated health (SRH) level and self-rated Mibyeong severity, and aimed to assess this relationship using a fully automated image analysis system. The nose size features were evaluated from the frontal and profile face images of 810 participants. The nose size features consisted of five length features, one area feature, and one volume feature. The level of SRH and the Mibyeong severity were determined using a questionnaire. The normalized nasal height was negatively associated with the self-rated health score (SRHS) (partial ρ = -0.125, p = 3.53E-04) and the Mibyeong score (MBS) (partial ρ = -.172, p = 9.38E-07), even after adjustment for sex, age, and body mass index. The normalized nasal volume (ρ = -.105, p = 0.003), the normalized nasal tip protrusion length (ρ = -.087, p = 0.014), and the normalized nares width (ρ = -.086, p = .015) showed significant correlation with the SRHS. The normalized nasal area (ρ = -.118, p = 0.001), the normalized nasal volume (ρ = -.107, p = .002) showed significant correlation with the MBS. The wider, longer, and larger the nose, the lower the SRHS and MBS, indicating that health status can be estimated based on the size and shape features of the nose.

• 동아시아식생활학회지
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• 제21권4호
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• pp.587-599
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• 2011

The purpose of this study was to examine self-perception of body image and dieting behaviors by gender among high school students. The data were collected by a self-administered questionnaire during April, 2010, and analyzed by SPSS Windows V.18.0. The results were as follows. First, many respondents showed a desire to be underweight and regarded themselves as overweight, even though they had a normal BMI. Second, female respondents showed a higher level of concern about diet than male respondents. Third, male respondents received information about diet mostly from their family or friends, whereas female respondents received information from blogs, mini-homepages, or Kin-search on the Internet. Finally, female respondents showed a higher level of practice for fasting therapy than male respondents, whereas male respondents showed a higher level of practice for food therapy, drug therapy, oriental medicine therapy, and steam bath therapy. Therefore, high school should educate students to get right recognition and knowledge of diet.

• 사상체질의학회지
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• 제19권3호
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• pp.51-61
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• 2007

1. Objectives The Face is an important standard for the classification of Sasang Constitutions. We are developing 3D Automatic Face Recognition Apparatus(3D-AFRA) to analyse the facial characteristics. This apparatus show us 3D image and data of man's face and measure facial figure data. So We should examine the Measurement of Facial Figure data error of 3D Automatic Face Recognition Apparatus(3D-AFRA) in Software Error Analysis. 2. Methods We scanned face status by using 3D Automatic Face Recognition Apparatus(3D-AFRA). And we measured lengths Between Facial Definition Parameters of facial figure data by Facial Measurement program. 2.1 Repeatability test We measured lengths Between Facial Definition Parameters of facial figure data restored by 3D-AFRA by Facial Measurement program 10 times. Then we compared 10 results each other for repeatability test. 2.2 Measurement error test We measured lengths Between Facial Definition Parameters of facial figure data by two different measurement program that are Facial Measurement program and Rapidform2006. At measuring lengths Between Facial Definition Parameters, we uses two measurement way. The one is straight line measurement, the other is curved line measurement. Then we compared results measured by Facial Measurement program with results measured by Rapidform2006. 3. Results and Conclusions In repeatability test, standard deviation of results is 0.084-0.450mm. And in straight line measurement error test, the average error 0.0582mm, and the maximum error was 0.28mm. In curved line measurement error test, the average error 0.413mm, and the maximum error was 1.53mm. In conclusion, we assessed that the accuracy and repeatability of Facial Measurement program is considerably good. From now on we complement accuracy of 3D-AFRA in Hardware and Software.

• Journal of Acupuncture Research
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• 제21권1호
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• pp.226-239
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• 2004

Objective: Purpose of this study was to examine the effect of electroacupuncture(EA) at Xingjian(LR2) as 'Fire(火)' point of The Leg Absolute Um Liver Meridan(足厥陰肝經 : Chok-Kworum-Kan-Kyong) on the facial thermal change. Methods: Subjects of this study were 15 patients with upperpart(includes head and facial part) fever of human body and two examinations were carried out in each other day. We divided cases of two examinations into two groups. One is experimental group(N=15) that was carried out electroacupuncture stimulation at Xingjian(LR2), the other is control group(N=15) which was carried out electroacupuncture stimulation at optional point(in space between 1st and 2nd fingers) except acupuncture points of 12 meridians. We took the temperature of fixed areas on face by digital infrared thermal image(D.I.T.I.) before and after electroacupuncture stimulation. Those fixed areas on face that was taken temperature are Jingming(BL1), Sibai(ST2), Dicang(ST4), Indang, Shuigou(GV26), Chengjiang(CV24) areas. In cases of temperature of Jingming(BL1), Sibai(ST2), Dicang(ST4) areas, we applied each mean of left and right temperature to statical analysis. Results: In the group of electroacupuncture stimulation at Xingjian(LR2), temperature of every fixed areas on face fell: Jingming(BL1) area's ${\Delta}T=-0.7007{\pm}0.78642$, Sibai(ST2) area's ${\Delta}T=-0.6280{\pm}0.56439$, Dicang(ST4) area's ${\Delta}T=-0.5940{\pm}0.60179$, Indang area's ${\Delta}T=-0.7200{\pm}0.64515$, Shuigou(GV26) area's ${\Delta}T=-0.6160{\pm}0.80487$, Chengjiang(CV24) area's ${\Delta}T=-0.5627{\pm}0.72615$. In Xingjian(LR2) electroacupuncture group, each temperature of Jingming(BL1), Sibai(ST2), Indang areas showed a drop significantly in comparison with control group (p<0.05). But each temperature of Dicang(ST4), Shuigou(GV26), Chengjiang(CV24) areas did not showed a drop significantly in comparison with control group(p>0.05). Conclusions: The results mentioned above showed that electroacupuncture stimulation at Xingjian(LR2) significantly decreased the temperature on face of patients with upperpart fever of human body. In Xingjian(LR2) electroacupuncture group, especially temperature of upper part of face includes eye, cheekbone, forehead regions showed a drop significantly in comparison with control group.

• 동의신경정신과학회지
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• 제19권2호
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• pp.111-122
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• 2008

Objective : Herb medicines are potential sources of useful edible and medicinal plants. They are used as a drug because of their various biological activities such as immunomodulatory, antiviral, and antitumor functions. Nelumbo nucifera have been applied in Chinese herbal prescriptions to improve tissue inflammation. However, it has not been elucidated on the effect of the flower of Nelumbo nucifera in cells. Method : In the present study, to examine the effect of that on glioma cells, U87, the essential oil was extracted from the flower of Nelumbo nucifera (NN essential oil). U87 cells were exposed to different concentrations of 2-40 ug/ml of NN essential oil in ethanol. Cell viability was measured by MTT assay at 24 h. To find out the intracellular target signal molecule(s) for this antiproliferative activity of NN essential oil, phosphorylation of Akt, ERM, MAPK or p38 proteins were examined by Western blot analysis. To study long term effect of NN essential oil in U87 cells, the image of cells treated with NN essential oil for 4 days were obtained. Results and Conclusion : NN essential oil was shown to exhibit antitumor activity in glioma cells, at a broad range of concentrations of 10-40 ug/ml. The phosphorylation of Akt and Endoplasmic Reticulum Matrix (ERM) proteins which known to be involved in the cell death, were gradually decreased to 2 hours after addition 20 ug/ml of NN essential oil. However, the phosphorylation of mitogen-activated protein (MAPK) and p38 was found to increase in NN essential oil treated cells. NN essential oil treated cells showed decreased glioma cell number. These results provide a possible NN essential oil-induced inhibitory signal for tumor cell proliferation that is initiated by the decrease in Akt activity. Moreover, it is likely that the activation of p38 is required for the NN essential oil-induced inhibition of tumor proliferation.

• 사상체질의학회지
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• 제19권2호
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• pp.22-29
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• 2007

1. Objectives Sasang Contitutional Medicine, a part of the traditional Korean medical lore, treats illness through a constitutional typing system that categorizespeople into four constitutional types. A few of the important criteria for differentiating the constitutional types are external appearances, inner state of mind, and pathological patterns. We had been developing a 3D Automatic Face Recognition Apparatus (3D-AFRA) in order to evaluate the external appearances with more objectivity. This apparatus provides a 3D image and numerical data on facial configuration, and this study aims to evaluate the mechanical accuracy of the 3D-AFRA hardware. 2. Methods Several objects of different shapes (cube, cylinder, cone, pyramid) were each scanned 10 times using the 3D Automatic Face Recognition Apparatus (3D-AFRA). The results were then compared and analyzed with data retrieved through a laser scanner known for its high accuracy. The error rates were analyzed for each grid point of facial contour scanned with Rapidform2006 (Rapidform2006 is a 3D scanning software that collects grid point data for contours of various products and products and product parts through 3D scanners and other 3D measuring devices; the grid point data thusly acquired is then used to reconstruct highly precise polygon and curvature models). 3. Results and Conclusions The average error rate was 0.22mm for the cube, 0.22mm for the cylinder, 0.125mm for the cone, and 0.172mm for the pyramid. The visual data comparing error rates for measurement figures retrieved with Rapidform2006 is shown in $Fig.3{\sim}Fig.6$. Blue tendency indicates smaller error rates, while red indicates greater error rates The protruding corners of the cube display red, indicating greater error rates. The cylinder shows greater error rates on the edges. The pyramid displays greater error rates on the base surface and around the vertex. The cone also shows greater error around the protruding edge.

• 대한한방부인과학회지
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• 제18권1호
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• pp.128-141
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• 2005

Objective : This study was undertaken to investigate the effects of Eucommiae Cortex on the osteoporosis in ovariectomized rats. Materials and Methods : We used Sprague-Dawley female rats in 8-week-old. They were divided into three groups. Sample group was ovariectomized and administered with 10 mg/100 g/day Eucommiae Cortex extract solution for 10 weeks. Control group was ovariectomized and sham group was conducted by sham's operation. And control group and sham group were administered with normal saline as the same way. We measured rats's body and uterus weight and also measured the serum levels of Ca, phosphorus and ALP. We stained the specimens of rat's tibial bones with Goldner's modified Masson's Trichrome and then examined bone histomorphometry with Bioquant computer program of image analysis system. We measured the thickness of osteoid and callus as static parameters and measured bone volume and mineral apposition rate as dynamic parameters. We observed the expressions of RANKL and OPG mRNA of the tibial bone by RT-PCR. Results : The body weight was significantly (p<0.05) increased in control and sample groups compared with sham group, respectively. The uterus weight was significantly (p<0.05) decreased in control and sample group compared with sham group. In the change of Ca, phosphorus and ALP there were no significant changes among three groups. There were no significant changes of trabecula cortical and osteoid bones' thickness and volume. But trabecula mineral apposition rate (MAR) was significantly (p<0.05) increased in sham and sample group compared with control group. In the expression of RANKL mRNA, sample group was decreased compared with control group, and in that of OPG mRNA, sample group was increased compared with control group. Conclusion : This study shows that Eucommiae Cortex has the beneficial effects on bone histomorphometry and metabolism in the ovariectomized rats. We suggest that Eucommiae Cortex be useful for the treatment of osteoporosis.