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A Case Study of Small-Cell Lung Cancer with Multiple Brain Metastases Patient who Showed Improvement of Delirium and Performance Status

섬망 증세와 신체 활동도에 호전을 보인 뇌전이가 있는 소세포폐암 환자 1례

  • Park, So-Ra (Graduate school of Clinical Korean Medicine, Kyung Hee University) ;
  • Lee, Soo-Min (Cancer Center of Traditional Korean Medicine, Kyung-Hee University Hospital at Gangdong, College of Oriental medicine, Kyung Hee University) ;
  • Choi, Seong-Heon (Cancer Center of Traditional Korean Medicine, Kyung-Hee University Hospital at Gangdong, College of Oriental medicine, Kyung Hee University) ;
  • Jung, Yee-Hong (Cancer Center of Traditional Korean Medicine, Kyung-Hee University Hospital at Gangdong, College of Oriental medicine, Kyung Hee University) ;
  • Lee, Soo-Kyung (Cancer Center of Traditional Korean Medicine, Kyung-Hee University Hospital at Gangdong, College of Oriental medicine, Kyung Hee University)
  • 박소라 (경희대학교 일반대학원 임상한의학과) ;
  • 이수민 (경희대학교 한의과대학 강동경희대학교병원 한방암센터) ;
  • 최성헌 (경희대학교 한의과대학 강동경희대학교병원 한방암센터) ;
  • 정의홍 (경희대학교 한의과대학 강동경희대학교병원 한방암센터) ;
  • 이수경 (경희대학교 한의과대학 강동경희대학교병원 한방암센터)
  • Received : 2014.10.24
  • Accepted : 2014.11.24
  • Published : 2014.12.31

Abstract

Objectives The aim of this study was to report the improvement of delirium and performance status in the small-cell lung cancer patient who had multiple brain metastases and pericardial effusion after Sasang constitutional treatment. Methods We retrospectively reviewed the medical records, medical laboratory and image scans of 71-year-old male patient diagnosed as small-cell lung cancer. Results The small-cell lung cancer with multiple brain metastases patient sometimes talked deliriously even after the whole brain radiation therapy. During the hospitalization period, he showed delirium. We treated him with Gihwangbaekho-tang and Dojeokgangki-tang as a main therapy. After treatment, he didn't show delirium and performance status was improved. Conclusions A small-cell lung cancer with multiple brain metastases patient showed the improvement of symptoms (delirium, poor performance status, constipation and poor oral intake) with the treatment of Gihwangbaekho-tang, Yanggyuksanhwa-tang and Dojeokgangki-tang.

Keywords

References

  1. J. Ferlay, I. Soerjomataram, R. Dikshit. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. International Journal of Cancer. 2014.
  2. Statistics Korea. Death statistics 2013. (Korean)
  3. Park JS, Rhee SH, Yim YN. A Clinical Report of the Patient with Limited-Stage Small Cell Lung Cancer. Korean J. Orient.Int.Med. 2005;26(3):677-684. (Korean)
  4. Bruera E, Bush SH, Willey J. Impact of delirium and recall on the level of distress in patients with advanced cancer and their family caregivers. Cancer. 2009;115(9): 2004-2012. https://doi.org/10.1002/cncr.24215
  5. Tuma R, DeAngelis LM. Altered mental status in patients with cancer. Arch Neurol. 2000;57(12):1727-1731. https://doi.org/10.1001/archneur.57.12.1727
  6. Kim SJ, Kim JY, Ryu CG. A Case Report of The Delirium Accompained Wi syndrome During The Treatment of Pneumonia. J. of Oriental Neuropsychiatry. 2011;22(2):71-83. (Korean) https://doi.org/10.7231/JON.2011.22.2.071
  7. Min SS, Kim YK, Kwon JN. Clinical Report on the Byun-jo Accompanied Delirium. Korean J. Oriental Physiology & Pathology. 2005; 19(6):1715-1719. (Korean)
  8. Jung JE, Jung WH, Seo SK.. The Effect of Oriental Medical Treatments on the Patients with Delirium; 4 Cases Report. J Oriental Rehab Med. 2009;19(2):303-313. (Korean)
  9. Choi BL, Song KC, An JJ. A case sutdy of small cell lung cancer patient. J.of Oriental Chr.Dis. 2003;9(1): 78-84.
  10. Sculier JP, Chansky K, Crowley JJ. The impact of additional prognostic factors on survival and their relationship with the anatomical extent of disease expressed by the 6th Edition of the TNM Classification of Malignant Tumors and the proposals for the 7th Edition. J Thorac Oncol. 2008;3:457. https://doi.org/10.1097/JTO.0b013e31816de2b8
  11. Posner JB. Management of brain metastases. Rev Neurol(Paris). 1992;148:477.
  12. Sperduto PW, Kased N, Roberge D. Summary report on the graded prognostic assessment: an accurate and facile diagnosis-specific tool to estimate survival for patients with brain metastases. J Clin Oncol. 2012;30: 419. https://doi.org/10.1200/JCO.2011.38.0527
  13. Clouston PD, DeAngelis LM, Posner JB. The spectrum of neurological disease in patients with systemic cancer. Ann Neurol. 1992;31(3):268. https://doi.org/10.1002/ana.410310307
  14. Tuma R, DeAngelis LM. Altered mental status in patients with cancer. Arch Neurol. 2000;57(12):1727-1731. https://doi.org/10.1001/archneur.57.12.1727
  15. Lipowski ZJ. Delirium (acute confusional states). JAMA. 1987;258(13):1789. https://doi.org/10.1001/jama.1987.03400130103041
  16. National federation of department of sasang constitutional medicine, colleges of oriental medicine. Sasang constitutional medicine. Seoul:Jipmoondang. 2011: 266-267, 396. (Korean)