• Journal of Sasang Constitutional Medicine
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• v.29 no.1
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• pp.40-49
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• 2017

Objectives Sleep duration and sleep quality are closely related to obesity, however there are few studies considering the Sasang constitution. This study is to investigate the relationship between sleep status and obesity according to Sasang constitution. Methods This cross-sectional research studied 2,672 participants (1,293 men and 1,379 women) using the Korean Medicine Data Center (KDC) of the KIOM. Sasang constitution was diagnosed by KS-15 questionnaire. Obesity was divided into two categories: general obesity was defined as Body Mass Index(BMI) ${\geq}25kg/m^2$, and abdominal obesity was defined as waist circumference ${\geq}90cm$ in men and ${\geq}85cm$ in women. Sleep quality was assessed using the Pittsburgh Sleep Quality Index. Results The distribution of the subjects was 56.9% for Taeumin and 43.1% for non-Taeeumin., Poor sleep quality increased both BMI and waist circumference in Taeeumin. In men Taeeumin, sleep duration was correlated with BMI, and sleep quality was correlated with waist circumference. The prevalence of obesity was significant difference according to sleeping duration in men Taeeumin, it was the highest at 6 hours of sleeping time. Conclusions Sleep duration and sleep quality was associated with obesity in Taeeumin. Especially, in men Taeeumin, adequate sleep duration was an important factor for prevention and treatment of obesity.

• Journal of Korean Medicine for Obesity Research
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• v.4 no.1
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• pp.139-160
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• 2004

The obesity is detrimental to the health of people living in affluent societies. Individual differences in energy metabolism are caused primarily by single nucleotide polymorphisms(SNPs), some of which promote the development of obesity-related type 2 diabetes mellitus. Type 2 diabetes mellitus is a common multifactorial genetic syndrome, which is determined by several different genes and environmental factors. In this review, five major conclusions are reached: (1)To be clinically significant, SNPs must be relevant, prevalent, modifiable, and measurable. (2)Differences in SNPs may have been caused by famine, ultraviolet light, alcohol, climate, agricultural revolution. livestock, lactase persistence, and westernized lifestyle. (3)Candidate obesity genes of calorie intake restriction are SIM 1, MC3R, MC4R, AGRP, CART, CCK, CNTFR, DRD2, Ghrelin, 5-HT receptor, NPY, PON and those of energy metabolism are LEP, LEPR, UCP1, UCP2, UCP3, B2AR, B3AR, PGC-1, Androgen receptor and those of fat mobilization are AGT, ACE, ADA, APM1, Apolipoproteins, PPAR, FABP, FOXC2, GCGR, $11-{\beta}HSDI$, LDLR, Hormonal sensitive lipase, Perilipin, $TNF-{\alpha}$, $TNF-{\beta}$ (4)Candidate obesity genes in the eastern are NPY, LEP, LEPR, UCP1, UCP2, UCP3, B2AR, B3AR, ACE, APM1, PPAR, and FABP. (5)Candidate obesity genes in type 2 diabetes mellitus are MC3R, MC4R, B2AR, B3AR, ADA, APM1, PPAR, FABP, FOXC2, PC1, PC2, ABCC8, CAPN10, CYP19, CYP7, ENPP1, GCK, GYS1, IGF, IL-6, Insulin receptor, IRS, and LPL. The discovery of SNPs will lead to a greater understanding of the pathogenesis of obesity and to better diagnostics, treatment, and eventually prevention.

• Journal of Korean Medicine Rehabilitation
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• v.20 no.2
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• pp.63-77
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• 2010

Objectives : It is known that abdominal obesity increases the possibility of cardiovascular diseases, early death, and metabolic syndrome including dyslipidemia and insulin resistance. Clinical trials have been under way to verify the effectiveness of treatment for abdominal obesity. The objective of this study is to set criteria about how effective oriental medicine and acupuncture are in abdominal obesity. Methods : I manually search "www.clinicaltrial.gov", 4 Korean medical databases and 4 Korean medical journals of abdominal obesity. Search terms used were "abdominal obesity" or "visceral obesity". In order to see detail review, searching was performed from 01, 01, 2005 to 11, 31, 2009. And I classified all the searched studies into design, intervention, purpose, end point, diseases, condition and etc. Results : 1. I could search total 67 trials in "www.clinicaltrial.gov". I found 9, 10, 13, 8, 6 clinical trial from 2005 to 2009 every year. 2. Test on both gender and adult or adult and senior have been most frequent. 3. Randomization clinical trial is 51 cases that occupied 96.2%. 38 cases use control group. 4. Body mass index(BMI) and waist circunference(WC) are major criteria of abdominal obesity clincal trial. WC, BMI, abdominal fat mass, body weight are measured at end point of abdominal obesity clincal trial. 5. I could search total 86 cases in domestic study. I found 15, 23, 23, 20, 5 cases from 2005 to 2009 every year. 6. Test on female and adult have been most frequent in domestic study. 7. Randomization clincal trial is only 2 cases that occupied 2.3%. 62 cases use control group in domestic study. 8. BMI, body fat percent, WC, visceral-subcutaneous fat ratio(VSR), waist-hip ratio(WHR) are criteria of abdominal obesity clincal trial in domestic study. WC, BMI, abdominal fat mass, body weight are measured at end point of abdominal obesity clincal trial in domestic study. Conclusions : To improve abdominal obesity study in traditional korean medicine, it is need to activate clinical trial, meta analysis, develope of clinical practice guidelines, co-works with conventional medicine and etc.

• Journal of Korean Medicine for Obesity Research
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• v.5 no.1
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• pp.21-29
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• 2005

Objectives : This study was carried out to evaluate the difference of body mass index(BMI) distribution and the difference of effect of weight reduction program among Sasang constitution. Methods : Sasang constitution was differentiated by QSCC II of 875 cases. Body composition was analysed by bioelectrical impedance analysis(Inbody 3.0, Biospace, Seoul, Korea) in before and after treatment to evaluate the effect among Sasang constitution. The weight reduction program including very low calorie diet, electrical acupuncture and herbal medicine was treated to all cases equally during 1 month. Results and Conclusions : The group of Taeum was more obese and less reducted in body fat mass and % body fat in tools of percent rates of the changes than other type of Sasang constitution. In conclusion, the group of Taeum is more easy to become obese and more difficult to treat obesity

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.6
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• pp.1026-1031
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• 2011

This experimental study was designed to investigate the inhibitory effects of hot water extract of Yukeuigambi-tang (YEGT) on high-fat diet-induced obesity and hyperlipidemia in C57BL/6 mice. Animals were divided into normal, control, YEGT(sample A 3.8 g/kg, and sample B 7.6 g/kg) treated group. Obesity with hyperlipidemia was induced by high fat diet treatment for 6 weeks. YEGT was given to the animals by oral gavage. The effect of YEGT on the body weight change, total cholesterol, HDL-cholesterol, LDL-cholesterol, triglyceride, and leptin levels in serum were evaluated. In respect to the body weight change, sample B significantly reduced body weight compared with control group in the 6th weeks. In the total cholesterol, triglyceride, and leptin level, sample B significantly reduced all of them compared with control group; sample A significantly reduced triglyceride and leptin levels compared with control group. The above results suggest that YEGT is effective to prevention and treatment of obesity and hyperlipidemia.

• Journal of Korean Medicine for Obesity Research
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• v.5 no.1
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• pp.147-155
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• 2005

Yak-ju treatment is regarded as a new way to give a medication, and used many parts of medical field such as musculo-skeletal, aesthetic and cosmetic part. Recently I've experienced a good result by Yak-ju treatment for managing obese patient who had failed to lose his weight by conventional existing treatments comprised of herbal medicine, electro-lypolysis, negative pressure, ear acupuncture, behavior modification therapy and education for diet and exercise. This method can be recommended as a new method for curing obesity that can make up for the weak point of existing ways.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.11 no.1
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• pp.65-74
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• 2016

Objectives : This study was designed to assess the general distribution, clinical effectiveness of Korean medical treatment on knee pain and the correlation between Korean medical therapy on knee pain and BMI. Methods : This is an observational study. 65 patients admitted to Daejeon Jaseng Hospital of Korean Medicine with musculoskeletal disorders were observed from July, 2014 to July, 2015. They were analyzed according to sex, age, pain lesion, body mass index(BMI) and treatment efficacy. All patients received a combination of treatments during hospitalization, including acupuncture, pharmacopuncture, herbal medicines and physical therapy. A zero to ten numerating rating scale (NRS) assessing pain, Western Ontario and McMaster Universities Arthritis Index(WOMAC) index and Range of Motion(ROM) was used before and after treatments. Statistical correlations among assessment measurements were evaluated by examining the paired t-test and the Pearson's correlation coefficients. Results : The average BMI of all patients was $24.03{\pm}2.95kg/m^2$. According to clinical definition of obesity by Korean Society for the Study of Obesity, 33.8% of all patients was within normal weight, 1.5% was underweight, 33.8% was overweight, 24.6% was obesity and 6.2% was morbid obesity. For knee pain patients, NRS (Numeric Rating Scale) decreased from $6.28{\pm}1.63$ to $3.94{\pm}2.03$(p<0.001). WOMAC index decreased from $48.14{\pm}17.63$ to $40.37{\pm}18.28$(p<0.001). But, there were no significant correlations in statistics among BMI, knee pain index and knee pain index improvement. Conclusions : Korean medical combination treatment might be effective in reducing pain and improving functional disorders for patients with knee pain. This study further confirmed the efficacy of Korean medical treatment on knee pain. But, more studies on correlation between knee pain and obesity and development of assessment measurement are needed.

• Journal of Physiology & Pathology in Korean Medicine
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• v.23 no.3
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• pp.548-553
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• 2009

In this study, after we analyzed 44 recent research paper written about obesity treatement, we tried to understand the acupuncture on the obesity treatment of the recent trend. We searched the recent papers with the key word of obesity, obese, and Acupuncture and are limited since 2004 in the search site KISS, KSI. Recently, acupuncture application for obesity treatment were 6 type. Traditional Acupuncture, Auricular Acupuncture, Electro Acupuncture, Herbal Acupuncture, Chi Acupuncture, and Acupoint Catgut Embedding Therapy. Although acupuncture application were effective method to decrease weight and localized fat, they were critical to evaluate to their effectiveness through strict and scientific clinical trials.

• Journal of Korean Medicine for Obesity Research
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• v.19 no.2
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• pp.113-118
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• 2019

A counseling manual for the standardized management of obesity in Korean Medicine was developed. Four specialist for obesity and ten advisors participated in the development. The development process was conducted in order to investigate the needs of clinical doctors for obesity, search for related books and references, determine the contents of the manual, produce the manual, and review of the advisors. The contents of the manual were written in order of goal of obesity counseling, assessment of obesity and health risk factors, assessment of obesity-related lifestyles, counseling for weight management, and counseling for Korean Medical treatment. This manual is the first standardized counseling manual developed, and it is meaningful to provide a counseling method for comprehensive Korean Medicine obesity care. Although there were various limitations in the review of the advisory committee, it is expected that this study will be used as a basic data for the establishment of obesity-related health care policy. We hope that obesity counseling of Korean Medicine will be settled as one of the certified korean medical treatment.

• The Journal of Pediatrics of Korean Medicine
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• v.37 no.1
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• pp.15-44
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• 2023

Objectives The purpose of this study is to analyze the types of childhood simple obesity and suggest clinical symptoms, treatment principles, and traditional Chinese medicine (TCM) treatments for each type. Methods All kinds of literature published by the China National Knowledge Infrastructure (CNKI) up to August 20, 2022 were analyzed. We extracted information about types of childhood simple obesity, relevant clinical symptoms, treatment principles and TCM treatments. Results 25 studies were included. Spleen deficiency with dampness obstruction, gastrointestinal dampness-heat, internal excess of phlegm-dampness were the most reported. Spleen deficiency with dampness obstruction has symptoms of powerless, heavy limbs, pale tongue, teeth-marked tongue, sunken and slippery pulse. As a treatment, herbal medicine (HM) like modified Banggihwanggitang and acupoint like Joksamri were mainly reported. Gastrointestinal dampness-heat has symptoms of thirst, constipation, edacity, rapid hungering, heavy limbs, red tongue, slippery and rapid pulse. HM like Modified Xiehuangsan to clear heat was mainly reported. Internal excess of phlegm-dampness has symptoms of heavy limbs, lack of strength, tongue with white slimy fur, slippery pulse. Modified Ijintang to dry dampness to resolve phlegm was mainly reported. Conclusions This study analyzed types of pattern, clinical symptoms, treatment principles, and TCM treatments of childhood simple obesity. Based on this study, it is necessary to derive a standardized dialectical information that reflects the domestic situation.