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Preparation of Nano Size Cerium Oxide from Cerium Carbonate (탄산(炭酸)세륨으로부터 나노크기 산화(酸化)세륨 제조연구(製造硏究))

  • Kim, Sung-Don;Kim, Chul-Joo;Yoon, Ho-Sung
    • Resources Recycling
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    • v.18 no.6
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    • pp.24-29
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    • 2009
  • Since cerium carbonate becomes porous cerium oxide by releasing carbon dioxide and vapour steam during calcination of cerium carbonate, nano size cerium oxide can be obtained by milling calcined cerium carbonate. Therefore cerium carbonate [$Ce_2(CO_3)3{\cdot}XH_2O$] is used generally for the preparation of nano size cerium oxide. In order to obtain nano size cerium oxide from cerium carbonate prepared by reactive crystallization of cerium chloride solution and ammonium bicarnonate solution, the effects of experimental variables in the milling and calcination of cerium carbonate, such as calcination temperature, milling time, rpm of planetary mill, amount of dispersant and ball size for milling on the size of cerium oxide was investigated in this study. Cerium oxide prepared with the conditions of calcination temperature of $700^{\circ}C$, milling time of 5 hour was 160nm mean particle size.

Analysis of Case Studies on Warts Treated with Oriental Medicine (사마귀의 한방 치료 증례연구 분석)

  • Lee, Kyou-Young
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.32 no.4
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    • pp.101-115
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    • 2019
  • Objectives : The purpose of this study is to analyze the use of herbal medicine as a treatment method in the case studies on warts in Korea, to identify trends in herbal medicines and herbal prescriptions according to the characteristics of individual patients and to systematically analyze concurrent therapies. Methods : Domestic databases (OASIS, RISS, NDSL, KTKP, KISS, KISTI, KISTI) were used to search for case studies related to the herbal medicine treatment of warts. There was no restriction on the time of publication. A total of 9 papers were selected. Results : A total of 13 prescriptions were presented 23 times in 18 cases. Among them, bojungikgi-tang gamibang(補中益氣湯加減方) was the most frequently prescribed. Gwakhyangjeonggi-san gamibang(藿香正氣散加減方) and Damsoeun-tang gagam were the next most frequently prescribed. 69 herbs were used in a total of 13 prescriptions. Herbs were commonly classified as heat-clearing medicine(淸熱藥), exterior-releasing medicine(解表藥), and tonifying and replenishing medicine(補益藥) in descending order. The herbs used more than 6 times included Coicis Semen(薏苡仁), Glycyrrhizae Radix et Rhizoma(甘草) (10 times), Bupleuri Radix(柴胡), and Scutellariae Radix(黃芩) (6 times). Concurrent therapies were performed except for 1 study, and they were acupuncture, moxibustion, pharmacopuncture, external agents, and cupping therapy. Conclusions : This is the first study to analyze the use of herbal medicine as a treatment method for warts in case studies performed in Korea. We hope that this study would give helpful information about the treatment of warts in clinical practices.

Effect of Banggibongnyeongtang on LPS-induced Depression in rats (방기복령탕(防己茯苓湯)이 흰쥐에서 LPS로 유도된 우울증에 미치는 효과)

  • Park, Sung jun;Lee, Tae Hee
    • Herbal Formula Science
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    • v.27 no.2
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    • pp.137-149
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    • 2019
  • Objective : This study is conducted in order to investigate the effect of Banggibongnyeongtang(BBT) on Lipopolysaccharide (LPS)-induced depression. Method : LPS $5{\mu}g$ was injected to lateral ventricle. Experimental groups were administered BBT intraperitoneally. Depressive behavior was confirmed by weight change, sucrose preference, open field test(OFT), and forced swimming test(FST). The plasma concentration of $IL-1{\beta}$ and $TNF-{\alpha}$, Corticotropin-Releasing Factor(CRF), Adrenocorticotropin Hormone(ACTH) and Corticosterone(CORT) were measured by ELISA. Result : BBT did not change the body weight significantly than LPS group, but on sucrose preference, BBT increased significantly in LPS+BBT400 group compared to LPS group (P<0.05). In the OFT, BBT increased spending time in the central zone and decreased grooming number. LPS+BBT400 group increased central zone-spending time, and decreased grooming number than LPS group significantly (P<0.05). In the FST, LPS+BBT400 group decreased immobility time than LPS group significantly (P<0.05). BBT decreased $IL-1{\beta}$ concentration does-dependently, but only with significant decrease in LPS+BBT400 group than LPS group in plasma (P<0.05). But BBT did not decrease $TNF-{\alpha}$ concentration significantly in plasma. BBT decreased plasma CRF, ACTH, and CORT. And CRH and CORT of LPS+BBT400 group were shown significant decrease comparing with LPS group (P<0.05). Conclusion : It is postulated that the anti-depressant effect of BBT can be validated through inhibition of HPA axis abnormal activity by the anti-inflammatory effect.

A Study on the Strategic Application of National Defense Data for the Construction of Smart Forces in the 4th IR (4차 산업혁명시대 스마트 강군 건설을 위한 국방 데이터의 전략적 활용 방안연구)

  • Kim, Seyong;Kim, Junsang;Kang, Seokwon
    • Convergence Security Journal
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    • v.20 no.4
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    • pp.113-123
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    • 2020
  • The fourth industrial revolution can be called the hyper-connected-based intelligent revolution triggered by advanced information technology and intelligent technology, and the basis for implementing these technologies is 'data'. This study proposes a way to strategically use data in order to lead this intelligent revolution in the defense area. First of all, implications through analysis of domestic and international trends and prior research and current status of defense data management were analyzed, and four directions for development were presented. If the government composes conditions for building, releasing, sharing, distribution, and convergence of defense data considering the environment of national defense in the future, it is expected that it will serve as a foundation and a shortcut to be a digitalized strong military through smart defense innovation in the era of the fourth industrial revolution.

A Study on the Characteristics of the Spatial Distribution and the Disparities in the Provision of Public Libraries in Busan (부산지역 공공도서관 분포의 특성과 공급 불균형 양상 분석)

  • Koo, Bon Jin;Chang, Durk Hyun
    • Journal of Korean Library and Information Science Society
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    • v.52 no.2
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    • pp.189-208
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    • 2021
  • Public library usage is closely related to the accessibility to library facilities. Therefore, public library planning and development authorities should consider the policies for improving the library accessibility of community, for releasing disparities of the spatial accessibility and for increasing location efficiency of public libraries. In this regard, this study strives to analyze the spatial distribution of public libraries in Busan and to derive the regions that lack public libraries by identifying main characteristics using geographical information systems (GIS): identify the blind spot for public library service, analyze the hot and cold spot for the supply of libraries, and identify the vulnerable areas of library based on population density. The result of the study will contribute to understand the spatial distribution of public libraries in Busan and to prioritize sites where public library should be constructed in order to improve the accessibility to public library services.

Flexible Energy Harvesting Device based on Hybrid Piezoelectric Nanocomposite made of Lead-Free BCTZ Ceramic and Piezo-polymer (비납계 BCTZ 압전세라믹과 압전폴리머로 제작된 하이브리드 나노복합체 기반의 플렉서블 에너지 하베스팅 소자)

  • Park, Sung Cheol;Lee, Jae Hoon;Kim, Yeon-gyu;Park, Kwi-Il
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.35 no.1
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    • pp.72-79
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    • 2022
  • Piezoelectric energy harvesting technologies, which can be used to convert the electricity from the mechanical energy, have been developed in order to assist or power the wearable electronics. To realize non-toxic and biocompatible electronics, the lead-free (Ba0.85Ca0.15)(Ti0.90Zr0.10)O3 (BCTZ) nanoparticles (NPs) are being studied with a great attention as flexible energy harvesting device. Herein, piezoelectric hybrid nanocomposites were fabricated using BCTZ NPs-embedded poly(vinylidene fluoride-trifluoroethylene) [P(VDF-TrFE)] matrix to improve the performance of flexible energy harvester. Output performance of the fabricated energy device was investigated by the well-optimized measurement system during the periodically bending and releasing motions. The generated open-circuit voltage and the short-circuit current of the piezoelectric hybrid nanocomposite-based energy harvester reached up to ~15 V and ~1.1 ㎂, respectively; moreover, the instantaneous power of 3.5 ㎼ is determined from load voltage and current at the external load of 20 MΩ. This research is expected to cultivate a new approach to high-performance wearable self-powering electronics.

Generation of cynomolgus monkey fetuses with intracytoplasmic sperm injection based on the MII-stage oocytes acquired by personalized superovulation protocol

  • Huang, Zhangqiong;Li, Yun;Jiang, Qinfang;Wang, Yixuan;Ma, Kaili;Li, Qihan
    • Journal of Veterinary Science
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    • v.21 no.3
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    • pp.48.1-48.18
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    • 2020
  • Background: Mature oocytes at the metaphase II status (MII-stage oocytes) played an important role in assisted reproductive technology in non-human primates. Objectives: In order to improve the proportion of MII-stage oocytes retrieval, three different superovulation protocols were performed on 24 female cynomolgus monkeys. Methods: All the monkeys received once-daily injection of follicle-stimulating hormone (25 international unit [IU]) on day 3 of the menstruation, 3-day intervals, twice daily for 8-12 days until the time of human chorionic gonadotropin (1,500 IU) injection, on the 14-17th day of menstruation collecting oocytes. The difference between protocol I and protocol II was that 0.1 mg the gonadotropin-releasing hormone agonist was injected on day 1 of the menstruation, while the difference between personalized superovulation protocol and protocol II was that oocytes could be collected on the 14-17th day of menstrual cycle according to the length of each monkey. Results: The total number of oocytes harvested using the personalized superovulation protocol was much higher than that using protocol I (p < 0.05), and the proportion of MII-stage oocytes was significantly greater than that from either superovulation protocol I or II (p < 0.001 and p < 0.01 respectively), while the proportion of immature oocytes at the germinal vesicle was less than that from superovulation protocol I (p < 0.05). Conclusions: The personalized superovulation protocol could increase the rate of MII-stage oocytes acquired, and successfully develop into embryos after intracytoplasmic sperm injection, and eventually generated fetus.

Minimize Web Applications Vulnerabilities through the Early Detection of CRLF Injection

  • Md. Mijanur Rahman;Md. Asibul Hasan
    • International Journal of Computer Science & Network Security
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    • v.23 no.2
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    • pp.199-202
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    • 2023
  • Carriage return (CR) and line feed (LF), also known as CRLF injection is a type of vulnerability that allows a hacker to enter special characters into a web application, altering its operation or confusing the administrator. Log poisoning and HTTP response splitting are two prominent harmful uses of this technique. Additionally, CRLF injection can be used by an attacker to exploit other vulnerabilities, such as cross-site scripting (XSS). Email injection, also known as email header injection, is another way that can be used to modify the behavior of emails. The Open Web Application Security Project (OWASP) is an organization that studies vulnerabilities and ranks them based on their level of risk. According to OWASP, CRLF vulnerabilities are among the top 10 vulnerabilities and are a type of injection attack. Automated testing can help to quickly identify CRLF vulnerabilities, and is particularly useful for companies to test their applications before releasing them. However, CRLF vulnerabilities can also lead to the discovery of other high-risk vulnerabilities, and it fosters a better approach to mitigate CRLF vulnerabilities in the early stage and help secure applications against known vulnerabilities. Although there has been a significant amount of research on other types of injection attacks, such as Structure Query Language Injection (SQL Injection). There has been less research on CRLF vulnerabilities and how to detect them with automated testing. There is room for further research to be done on this subject matter in order to develop creative solutions to problems. It will also help to reduce false positive alerts by checking the header response of each request. Security automation is an important issue for companies trying to protect themselves against security threats. Automated alerts from security systems can provide a quicker and more accurate understanding of potential vulnerabilities and can help to reduce false positive alerts. Despite the extensive research on various types of vulnerabilities in web applications, CRLF vulnerabilities have only recently been included in the research. Utilizing automated testing as a recurring task can assist companies in receiving consistent updates about their systems and enhance their security.

Synthesis, Characterization and Cosmetic Application of Self-Assembled Sericin-PEG Nanoparticle

  • E. S. Choung;S. Y. Eom;Kim, J. H.;Kim, K. S.;Kim, K. H.;Lee, K. G.;Lee, Y. W.;C. S. Cho
    • Proceedings of the SCSK Conference
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    • 2003.09a
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    • pp.501-519
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    • 2003
  • Silk Sericin(SS) is a natural protein extracted from cocoon of bombix mori and shows moisturizing effect to the skin due to a number of hydroxyl groups in the structure. But its application to cosmetics is limited due to its poor solubility in water. In order to solve this drawback and expand its application to cosmetics, polyethyleneglycol(PEG) was conjugated with sericin by reacting activated polyethyleneglycol(ActPEG). Reaction site of sericin is tyrosine residue, which was determined by using $^1$H-NMR. Random coil structure of sericin was transformed to beta-sheet structure by conjugating polyethyleneglycol. It was confirmed that melting point of sericin-PEG conjugate was lowered compared to that of each sericin and PEG due to the interaction between sericin and PEG in crystalline structure. Self-assembled sericin-PEG nanoparticle was obtained by dialyzing with alcohol solution of sericin-PEG conjugate against water. The particle is spherical and has 200-400nm of size. The moisturizing ability of sericin-PEG nanoparticle was much higher than that of sericin itself. Incorporation of vitamin A into sericin-PEG nanoparticle was carried out by diafiltration method. The content of incorporated Vitamin A in sericin-PEG nanoparticle was 8.9 wt%. Releasing behaviour of vitamin A incorporated into nanoparticle was tested in phosphate buffer, pH 7.4 at 37$^{\circ}C$. and half-life of Vitamin A release was 43hrs. Sericin-PEG nanoparticle exhibited higher moisturing effect than sericin itself and distilled water, respectively. No toxicity and irritation were observed in animal tests. It can be expected that the self-assembled sericin-PEG nanoparticle can be developed for cosmetics.

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A Study on the Fatigue of Hospital Nurses in Gwangju and Jeonnam Region (광주$\cdot$전남지역 병원 간호사의 피로 연구)

  • Kim Yeong Hie;Cho Soo Hyun
    • Journal of Korean Public Health Nursing
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    • v.16 no.2
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    • pp.271-284
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    • 2002
  • This study was to provide basic materials to help reduce the fatigue by analyzing what effective factor the fatigue of hospital nurses in Gwangju and Jeonnam region. and what causes their fatigue. This descriptive research by Questionaires includes two hospitals in Gwangju. and seven hospitals in Jeonnam region, total 9 hospitals sampled at convenience sampling. The periods of collecting data was from Jul.22, 2002 to Jul. 30, 2002. Multidimensional Fatigue Scale; MFS, developed by Jang Se-Jin(2000) was taken to measure the fatigue. All collected materials were got the statistics by SAS for Windows Release 8.01. The result of this study was as follows. 1. This study included total 740 nurses, whose age ranged from 22 to 50; 30 years old by average. Nurses fatigue mean score was 90.24 (the scope by the measuring instrument is 19-133). Nurses at University Hospitals marked 92.36 and those at General Hospitals marked 87.91 in the mean score of fatigue. 2. They kept tired at work, and felt more tired while working at computer in the hospital. 3. The part of body in which they felt fatigue was the calf and $feet(36.6\%)$, the shoulders and back of the $neck(30.7\%)$, and the whole $body(10.8\%)$ and the reason that they felt tired at work was mental $stress(33.0\%)$, overworking(25.2\%)$, and irregular working $conditions(14.7\%)$ in order. 4. The solution to their fatigue at work appeared nothing by $50.1\%$, and the way of releasing fatigue after work indicated getting some $sleep(30.8\%)$, and taking a bath or a $shower(21.7\%)$ in order. 5. The degree of fatigue depending on whether they were satisfied with their pay and labor condition appeared low: and when they were satisfied with doctors. and when they were getting on well with caregivers. 6. The effective factor of the degree of fatigue appeared: the influence that fatigue in the hospital makes on daily life was $10.6\%$, the cause of fatigue at work, $9.3\%$, time of fatigue at work, $7.8\%$, the relationship with caregivers, $5.3\%$. and these explanatory$(R^2)$ variables.$33\%$. To conclude. the degree of nurses' fatigue appeared high. and it was higher in nurses at University Hospitals than in ones at General Hospitals. In addition, the influence that fatigue from the hospitals made on daily life was the most explanatory.

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