• Title/Summary/Keyword: Optimum solutions

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Optimization of Nanoencapsulation Process for Azelaic Acid-Milk Nano Powder and Acne Nanocosmetics (Azelaic Acid 함유 밀크 나노분말과 여드름 나노화장품을 위한 나노캡슐의 최적화 공정)

  • Kim, Dong-Myong;Choi, Ji-Eun;Kim, Duck-Hoon;Lee, Jun-Tack
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.37 no.1
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    • pp.43-53
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    • 2011
  • The conditions in fluid-bed processor for nanoencapsulation of azelaic acid-milk nano powder for acne nanocosmetics were optimized by response surface methodology (RSM). The maximum value of yield was 70.97 %. The yield was appreciably influenced by inlet air temperature, atomizing pressure, and feeding speed. The particle size increased with an increase in the feeding speed and a decrease in the atomizing pressure. The elution rate in saline solutions was appreciably influenced by inlet air temperature and atomizing pressure. The moisture content increased with higher atomizing pressure, which was demonstrated to be similar to the nanoencapsulation characteristics related to water activity. The Hunter's L and b values increased with an increase in the inlet air temperature. The optimum conditions estimated by RSM for the maximized values of yield, moisture content, particle size and elution rate in skin suitability were $67{\sim}73^{\circ}C$ of inlet air temperature, 0.6 ~ 0.8 mL/min feeding speed and 1.8 ~ 2.0 kg/$cm^2$ of atomizing pressure, respectively. These estimated values were in agreement with those measured by real experiments.

Ni0.5Zn0.4Cu0.1Fe2O4 Complex Ferrite Nanoparticles Synthesized by Chemical Coprecipitation Predicted by Thermodynamic Modeling

  • Kang, Bo-Sun;Park, Joo-Seok;Ahn, Jong-Pil;Kim, Kwang-Hyun;Tae, Ki-Sik;Lee, Hyun-Ju;Kim, Do-Kyung
    • Journal of the Korean Ceramic Society
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    • v.50 no.3
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    • pp.231-237
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    • 2013
  • Thermodynamic modeling of the $Ni_{0.5}Zn_{0.4}Cu_{0.1}Fe_2O_4$ complex ferrite system has been adopted as a rational approach to establish routes to better synthesis conditions for pure phase $Ni_{0.5}Zn_{0.4}Cu_{0.1}Fe_2O_4$ complex ferrite. Quantitative analysis of the different reaction equilibria involved in the precipitation of $Ni_{0.5}Zn_{0.4}Cu_{0.1}Fe_2O_4$ from aqueous solutions has been used to determine the optimum synthesis conditions. The spinel ferrites, such as magnetite and substitutes for magnetite, with the general formula $MFe_2O_4$, where M= $Fe^{2+}$, $Co^{2+}$, and $Ni^{2+}$ are prepared by coprecipitation of $Fe^{3+}$ and $M^{2+}$ ions with a stoichiometry of $M^{2+}/Fe^{3+}$= 0.5. The average particle size of the as synthesized $Ni_{0.5}Zn_{0.4}Cu_{0.1}Fe_2O_4$, measured by transmission electron microscopy (TEM), is 14.2 nm, with a standard deviation of 3.5 nm the size when calculated using X-ray diffraction (XRD) is 16 nm. When $Ni_{0.5}Zn_{0.4}Cu_{0.1}Fe_2O_4$ ferrite is annealed at elevated temperature, larger grains are formed by the necking and mass transport between the $Ni_{0.5}Zn_{0.4}Cu_{0.1}Fe_2O_4$ ferrite nanoparticles. Thus, the grain sizes of the $Ni_{0.5}Zn_{0.4}Cu_{0.1}Fe_2O_4$ gradually increase as heat treatment temperature increases. Based on the results of Thermogravimetric Analysis (TGA) and Differential Scanning Calorimeter (DSC) analysis, it is found that the hydroxyl groups on the surface of the as synthesized ferrite nanoparticles finally decompose to $Ni_{0.5}Zn_{0.4}Cu_{0.1}Fe_2O_4$ crystal with heat treatment. The results of XRD and TEM confirmed the nanoscale dimensions and spinel structure of the samples.

B1+ Homogenizaion over Whole Field of View in High Field MRI (고자장 MRI에서의 영상 영역에 대한 B1+ 균질성)

  • Kim, Hong-Joon;Son, Hyeok-Woo;Cho, Young-Ki;Yoo, Hyoung-Suk
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.23 no.1
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    • pp.96-100
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    • 2012
  • In high static field magnetic resonance imaging(MRI) systems, $B_0$ fields of 7 T and 9.4 T, the impressed RF field shows larger inhomogeneity than in clinical MRI systems with B0 fields of 1.5 T and 3.0 T. In multi-channel RF coils, the magnitude and phase of the input to each coil element can be controlled independently to reduce the non-uniformity of the impressed RF $B_1^+$ field. The convex optimization technique has been used to obtain the optimum excitation parameters with iterative solutions for homogeneity in a selected ROI(Region of Interest). To demonstrate the technique, the multichannel transmission line coil was modeled together with a human head phantom at 400 MHz for the 9.4 T MRI system and $B_1^+$ fields are obtained. In this paper, all the optimized $B_1^+$ in each isolated ROIs are combined to achieve significantly improved homogeneity over the entire field of view. The simulation results for 9.4 T MRI systems are discussed in detail.

A Study on Design of Optimal Location for Renewable Energy Facility Using GIS (GIS를 사용한 재생에너지설비 최적 위치 설계에 관한 연구)

  • Jung, Moon-Seon;Moon, Chae-Joo;Chang, Young-Hak;Kim, Young-Gon;Lee, Sook-Hee
    • The Journal of the Korea institute of electronic communication sciences
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    • v.13 no.2
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    • pp.357-368
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    • 2018
  • For well over 100 years, oil has enabled remote communities to generate electricity and enjoy the benefits of a consistent electrical supply. Relying solely on oil for electricity generation has left island and remote communities exposed to several risks and drawbacks. Oil-based electricity generation is often more expensive and subject to price volatility, which can result in the use of risky fuel hedging strategies. The residents of islands and remote communities express concern over the future impacts of climate change or insist on their opinions for the corresponding action with reduction of carbon emissions. These risks and drawbacks can be overcomed with continuing cost reductions in solar, wind, and energy storage technologies by maker. Reducing costs is not always a straightforward process, relying on more diversely and renewably arranged renewable energy sources led to reduced local construction cost in every situation reviewed in this study. In this paper, a convenient and simple design solution which will facilitate the optimum location and transmission route of renewable energy facility using GIS(Geographic Information System) is proposed. The suggested solutions exercised to the case of geomoon island using GIS and identified by local site survey.

Development of Copycat Harmony Search : Adapting Copycat Scheme for the Improvement of Optimization Performance (모방 화음탐색법의 개발 : 흉내내기에 의한 최적화 성능 향상)

  • Jun, Sang Hoon;Choi, Young Hwan;Jung, Donghwi;Kim, Joong Hoon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.9
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    • pp.304-315
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    • 2018
  • Harmony Search (HS) is a recently developed metaheuristic algorithm that is widely known to many researchers. However, due to the increasing complexity of optimization problems, the optimal solution cannot be efficiently found by HS. To overcome this problem, there have been many studies that have improved the performance of HS by modifying the parameter settings and incorporating other metaheuristic algorithms. In this study, Copycat HS (CcHS) is suggested, which improves the parameter setting method and the performance of searching for the optimal solution. To verify the performance of CcHS, the results were compared to those of HS variants with a set of well-known mathematical benchmark problems. The effectiveness of CcHS was proven by finding final solutions that are closer to the global optimum than other algorithms in all problems. To analyze the applicability of CcHS to engineering optimization problems, it was applied to a design problem for Water Distribution Systems (WDS), which is widely applied in previous research. As a result, CcHS proposed the minimum design cost, which was 21.91% cheaper than the cost suggested by simple HS.

Effects of Acidic Treatments for Anthocyanin and Proanthocyanidin Extraction on Black Bean (Glycine max Merrill.) (검정콩 안토시아닌 및 프로안토시아니딘 추출에 대한 산 처리의 영향)

  • Ji, Yeong Mi;Kim, Min Young;Lee, Sang Hoon;Jang, Gwi Yeong;Li, Meishan;Yoon, Nara;Kim, Kyung Mi;Lee, Junsoo;Jeong, Heon Sang
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.44 no.10
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    • pp.1594-1598
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    • 2015
  • This study was performed to investigate the effects of various acidic treatment for anthocyanin and proanthocyanidin extraction from black bean. Extracts were prepared with 80% methanol solutions containing HCl, acetic, formic, phosphoric, and citric acids of different concentrations (0.1, 0.2, 0.3, 0.5, and 0.7%). Total anthocyanin content ranged from 0.74 mg/g in 0.7% citric acid to 1.74 mg/g in 0.3% HCl, depending on acid type and concentration. The major anthocyanins were delphinidin-3-glucoside (D3G), cyanidin-3-glucoside (C3G), and petunidin-3-glucoside (Pt3G). The highest C3G content was 1.12 mg/g in 0.3% HCl. Proanthocyanidin content ranged from 2.01 mg/g in 0.5% acetic acid to 5.29 mg/g in 0.3% HCl. Thus, acidic condition is a significant factor affecting anthocyanin and proanthocyanidin extraction from black bean, and the optimum extraction conditions were determined as 80% methanol containing 0.3% HCl.

Biochemical changes and drug residues in ascidian Halocynthia roretzi after formalin-hydrogen peroxide treatment regimen designed against soft tunic syndrome

  • Lee, Ji-Hoon;Kim, Ju-Wan;Shin, Yun-Kyung;Park, Kyung-Il;Park, Kwan Ha
    • Fisheries and Aquatic Sciences
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    • v.20 no.7
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    • pp.12.1-12.7
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    • 2017
  • Soft tunic syndrome (STS) is a protozoal disease caused by Azumiobodo hoyamushi in the edible ascidian Halocynthia roretzi. Previous studies have proven that combined formalin-hydrogen peroxide ($H_2O_2$) bath is effective in reducing STS progress and mortality. To secure target animal safety for field applications, toxicity of the treatment needs to be evaluated. Healthy ascidians were bathed for 1 week, 1 h a day at various bathing concentrations. Bathing with 5- and 10-fold optimum concentration caused 100% mortality of ascidians, whereas mortality by 0.5- to 2.0-fold solutions was not different from that of control. Of the oxidative damage parameters, MDA levels did not change after 0.5- and 1.0-fold bathing. However, free radical scavenging ability and reducing power were significantly decreased even with the lower-than-optimal 0.5-fold concentration. Glycogen content tended to increase with 1-fold bathing without statistical significance. All changes induced by the 2-fold bathing were completely or partially restored to control levels 48 h post-bathing. Free amino acid analysis revealed a concentration-dependent decline in aspartic acid and cysteine levels. In contrast, alanine and valine levels increased after the 2-fold bath treatment. These data indicate that the currently established effective disinfectant regimen against the parasitic pathogen is generally safe, and the biochemical changes observed are transient, lasting approximately 48 h at most. Low levels of formalin and $H_2O_2$ were detectable 1 h post-bathing; however, the compounds were completely undetectable after 48 h of bathing. Formalin-$H_2O_2$ bathing is effective against STS; however, reasonable care is required in the treatment to avoid unwanted toxicity. Drug residues do not present a concern for consumer safety.

Preparation and Keeping Quality of Intermediate Moisture Food from Oyster and Sea Mussel (굴, 홍합의 중간수분 식품제조 및 저장 안정성에 관한 연구)

  • Jo, Kil-Suk;Kim, Hyun-Ku;Kang, Tong-Sam;Shin, Dong-Hwa
    • Korean Journal of Food Science and Technology
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    • v.20 no.3
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    • pp.363-370
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    • 1988
  • An attempt was made in this study to investigate the possibility of processing oyster and sea mussel into an intermediate moisture food. To obtain a palatable and instant product, shucked samples were heated in soy sauce for 5 min., heated in seasoning solution for 10 min., and then dried by the method of hot-air blowing for 4-6 hours at $40^{\circ}C$. Optimum seasoning solutions consisted of 2% monosodium glutamate, 3.5% sodium chloride, 15% sorbitol, 2% propylene glycol, 5% glycine and 0.02% rosemary oleoresin in 72.48% water. Judging from water activity, thiobarbituric acid, viable cell count, volatile basic nitrogen, surface color and sensory evaluation, vacuum-packaging method in nylon/PE $(20{\mu}m/40{\mu}m)$ or polyester/viniliden chloride/polypropylene $(12{\mu}m/15{\mu}m/50{\mu}m)$ film bag did hardly damage to the quality of intermediate moisture products, but air-packaging method in polyethylene(0.06m/m) bag did considerable damage to the quality during storage for 60 days in an incubator with 49-51% relative humidity at $30^{\circ}C$.

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A Role of Standard Material in Rare Earth Element Analysis by ICP-MS (ICP-MS를 이용한 희토류원소 분석시 표준시료의 선택이 미치는 영향)

  • Lee Seung-Gu;Kim Kun-Han;Song Yong Sun;Kim Yongje
    • The Journal of the Petrological Society of Korea
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    • v.14 no.4 s.42
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    • pp.237-250
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    • 2005
  • In order to clarify the effect of standard rock material in the chemical analysis of rare earth element abundance with ICP-MS, we measured rare earth element abundance of KIGAM granite standard rock material (KG-1), USGS granite standard rock material (G-2), GSJ granite standard rock materials (JG-1a and JG-2). In REE analysis, we used conventional calibration standard solutions, KG-1, JG-1a, JG-2 and G-2 as standard material, respectively. Chondrite-normalized LREE patterns of low granite standard material correspond well each other in the recommended value and the estimated value regardless of a kind of standard rock. However, the HREE patterns of the estimated value based on G-2 or JG-2 and the recommended value are different from each other. Such difference may be due to the wrong recommended value or a specific geochemical properly of the standard rock material itself, The chondrite-normalized REE patterns of four standard rock materials estimated on the basis of KG-1 or JG-1 a show little deviation compared to the those of the recommended values. This suggests that KG-1 and JG-1a may be a optimum standard material for granitoids.

A Study on the Magnetic Properties of the Co-Ni-P thin Plate by Electroless Plating (무전해도금법에 의한 Co-Ni-P 박막의 자기적특성에 관한 연구)

  • Kim, C.W.;Lee, C.;Yoon, S.R.;Joung, I.
    • Korean Journal of Materials Research
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    • v.5 no.8
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    • pp.1013-1019
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    • 1995
  • The thin plate of Co-Ni-P was deposited on the polyester film by the electroless plating method. Through present experiments, deposition rates and metal compositions of the plates were determined according to compositions of solution, pH and temperature. Also, magnetic properties of plates were examined according to metal compositions. Considering magnetic properties and deposition rates of electroless plating, the best condition was obtained as pH of 8.5 and 90℃. It was observed that metal compositions were evidently varied by the pH of solutions and the concentration of complex agents. However. they were not affected by other factors. At the optimum condition, the composition of the plate was Co(78%), Ni(16%), and P(6%). Also, it was found that the coercive force was 370 Oe, and squareness was 0.65 at this condition. Magnetic properties (hard or soft) of thin plates were determined by metal compositions. Therefore. the plate became soft magnetic plate as the composition of nickel increased over 30 per cents. The crystal structure of the soft magnetic plate was found to be amorphous in which it was strongly oriented to the (111)phahe of nickel. On the ohter hand, the hard magnetic place was found to be hcp crystalline of α-cobalt which was oriented to the (101)phase of cobalt and the (100)phase of cobalt.

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