• Journal of Physiology & Pathology in Korean Medicine
• /
• v.33 no.2
• /
• pp.89-101
• /
• 2019

In recent times, the number of men with late-onset hypogonadism has increased, and interest on this topic has also increased. This study was conducted to investigate effects of the mixture extract of Fructus amomi Amari, Eucommiae cortex, Bombyx batryticatus on improve late-onset hypogonadism. The experimental subjects consisted of three groups: a control group consisting of 8-week-old male ICR mice that had undergone no treatment, an aging-elicited group (AE group) consisting of 50-week-old ICR male mice that had undergone no treatment, and a Mixed herbal extract treatment group (MT group) consisting of 50-week-old ICR male mice that had undergone the mixture extract of Fructus amomi Amari, Eucommiae cortex, Bombyx batryticatus treatment (0.1 g/kg/day) for 6 months. After the experiment, the mice from all the experimental groups were dissected, and they were analyzed through histochemical and immunohistochemical methods. The mixture extract of Fructus amomi Amari, Eucommiae cortex, Bombyx batryticatus reduces aging-induced cell damage and oxidative stress and increases the secretion of serotonin and B-endorphin in aged mice, and promotes spermatogenesis in seminiferous tubules and reduces apoptosis and oxidative stress, and increases androgen receptor, $17{\beta}-HSD$ and GnRH, increases the ratio of smooth muscle to collagen fibers in the corpus cavernosum, increases eNOS, decreases PDE-5 and oxidative stress in aged mice, so it improves depression, reproductive, sexual problems caused by Late-onset hypogonadism. the mixture extract of Fructus amomi Amari, Eucommiae cortex, Bombyx batryticatus inhibits the induction of osteoporosis by increasing decreased bone matrix distribution due to aging, increasing the activities of OPC and OPN, which are produced in osteoblasts, and decreasing RANKL, MMP-3 activity, increasing OPG activity. It also reduces muscle damage, oxidative stress, inflammation and apoptosis of muscle tissue, and increases Myo-D in the sartorius muscle of aged mice for improving muscle atrophy caused by by Late-onset hypogonadism.

• Korean Journal of Food Science and Technology
• /
• v.52 no.6
• /
• pp.587-594
• /
• 2020

In this study, we analyzed glucosinolates and their metabolites in the inner and outer parts of napa cabbage (NC; Brassica rapa subsp. pekinensis) and napa cabbage kimchi (NKC) using UPLC-ESI-MS/MS. In the extracts from NC and NKC, glucobrassicanapin (m/z 386), glucoalyssin (m/z 450), glucobrassicin (m/z 447), 4-methoxyglucobrassicin (m/z 477), and neoglucobrassicin (m/z 477) were detected using the MS scan mode ([M-H]-), and gluconapin (m/z 372→97), progoitrin (m/z 388→97), glucoiberin (m/z 422→97), 4-methoxyglucobrassicin (m/z 477→97), and neoglucobrassicin (m/z 477→447) were detected using the MS/MS MRM mode ([M-H]-). Ascorbigen (m/z 306→130) and indole-3-carboxaldehyde (I3A; m/z 146→118), which were metabolites of glucobrassicins, were detected using the MS/MS MRM ([M+H]+) mode. The peak intensities of ascorbigen in the extract from the inner and outer parts of NC were significantly higher than those of the NKC extract (p<0.05); however, there was no significant difference in I3A peak intensity between the NC and NKC extracts.

• Journal of the Korean earth science society
• /
• v.43 no.3
• /
• pp.386-404
• /
• 2022

From April 29 to 30, 2011, under the influence of Asian dust originated from Mongolia, a high concentration of Asian dust was observed nationwide for 4 days in Korea. This study investigated the causes and characteristics of and weather conditions associated with Asian dust at high concentrations at its source in Mongolia. For analysis, Asian dust weather data, Asian dust monitoring tower data, satellite data, backward trajectory data, observation data (PM₁₀ and OPC data), and ECMWF reanalysis data were used. In the synoptic analysis, it was observed that the intervals of isobars were densely distributed in the central region of Mongolia and the pressure gradient force was strong. It could be inferenced that Asian dust occurred due to strong winds. The temperature was relatively high, above 10℃, just before the occurrence of Asian dust, and it decreased sharply at the onset of the dust. The relative humidity had a low value of less than approximately 40%. After the occurrence of Asian dust, it increased sharply to over 50% and then showed a tendency to decrease. In the aerosol index shown by the COMS satellite, a high concentration value of over 25 was detected in Inner Mongolia, and it was consistent with the observations made with naked eyes. In the 72-hour backward trajectory, the northwest airflow streamed into Korea, and on May 2, Heuksando showed the highest PM₁₀ concentration of 1,025 ㎍ m^-3(times the average). Especially, in kinematic vertical analysis, it was observed that low pressure on the ground was strengthened by cyclonic relative vorticity developed in the upper layer. Also, the vertical velocity development is considered to have played a major role in the occurrence of high concentration Asian dust.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.26 no.1
• /
• pp.67-72
• /
• 2022

Concrete prevents corrosion of reinforcing bars due to its strong alkalinity. However, in the sea, strong alkali components with a pH of 12 to 13 are eluted, which adversely affects the ecological environment and growth of marine organisms. In this study, the mechanical properties and durability of the low alkali mortar were evaluated for the development of a low alkali mortar for the 3D printed artificial reefs. As a result of evaluation of strength characteristics, the α-35 mixture, which were produced with fly ash, silica fume and α-hemihydrate gypsum, satisfied the strength requirement 27 MPa in terms of compressive strength. As a result of pH measurement, it was found that mixing with alpha-type hemihydrate gypsum resulted in minimizing pH due to the the formation of calcium sulfate instead of calcium hydroxide production. As a result of the chloride ion penetration resistance test, the α-35 mixture exhibited the best performance, 3844C. As a result of measuring the length change over time, the α-35 mixture showed the shrinkage 33.5% less compared to the Plain mix.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.26 no.2
• /
• pp.76-83
• /
• 2022

Since the 3D printing mortar is exposed to the atmosphere immediately after printing, moisture is largely evaporated from the surface of the layer. The evaporation of moisture on the surface of the layer greatly causes drying shrinkage and increases the risk of cracking and damage to the structure due to drying shrinkage. This study experimentally evaluated the shrinkage behavior of the initial age using the mortar used for 3D printing. The change in shrinkage was evaluated by comparing the shrinkage of the specimen cured by the sealing method and the atmospheric exposure method. In addition, compared with the case where type 1 cement was used 100%, the shrinkage amount was evaluated when 20% of fly ash was replaced and 10% of silica fume was used. In particular, the effect of three chemical admixtures applied using 3D printing on shrinkage was evaluated experimentally. When fly ash and silica fume were used, the shrinkage amount increased by 60 - 110% compared to the case when type 1 cement was used. The application of viscosity modifiers and shrinkage reducers reduced the shrinkage by at least 18% and at most 70% depending on the curing conditions. The temperature of the specimen temporarily decreased to 15 ℃ at the beginning of curing, and the correlation between the internal temperature of the specimen and the shrinkage behavior was observed.

• Journal of the Korean Recycled Construction Resources Institute
• /
• v.10 no.3
• /
• pp.227-234
• /
• 2022

In this study, the rheological properties of cement paste composites applied with carbon-based nano-materials were experimental analyzed. Flow table and rheological properties, compressive strength were measured in the cement paste using graphene oxide asqueous solution and carbon nanotube aqueous solution. When carbon nano-materials was mixed in an aqueous solution, flow decreased and plastic viscosity and shear stress were increased. In particular, graphene oxide rapidly increased the plastic viscosity and shear stress. In the case of carbon nanotube aqueous solution, when less than 0.2 % was mixed, the increase rate was low compared to graphene oxide. This is because the specific surface area of graphene, which is in the form of a plate, is large. The compressive strength showed a small amount in strength increase when graphene mix, and CNT had a strength about 112 % of OPC. Carbon-based nanomaterials, is considered that CNT are suitable more to be used construction materials. However, extra studies on the surfactant to be used for mixing proportion and dispersion will be needed.

• Journal of the Korean Recycled Construction Resources Institute
• /
• v.11 no.1
• /
• pp.9-15
• /
• 2023

The cement is a typical CO₂ emission industry. Manufacturing process improvements and increased use of alternative materials are needed to reduce energy consumption and CO₂ emissions. This study confirmed the basic characteristics of cement hydration by sintering CAF at low temperature as a CO₂ adsorbent material. For the hydration product of the synthetic CAF, crystal phase analysis, porosity, and structural images were confirmed, and the compressive strength was measured. The replacement rate of SCAF was 10, 20, and 100 %, and the compressive strength tended to decrease as the replacement rate increased. In addition, when the SCAF substitution rate is 100 %, the hydration products of the early age are calcium aluminum oxide hydrate (Ca₃Al₂O₆ x H₂O) and calcium iron hydroxide (Ca₃Fe(OH)₁₂), and at substitution rates of 10 and 20 %, CAF compounds other than general cement hydrates brownmillerite was observed. As for the porosity, the pore size increased and the porosity increased with the increase of the replacement ratio. As a result of this study, CAF manufactured by low-temperature sintering seems to be difficult to use alone and general curing for utilization as a CO₂ adsorbing material.

• Journal of the Korea Concrete Institute
• /
• v.27 no.2
• /
• pp.127-136
• /
• 2015

To evaluate the effects of limestone powder and silica fume on the properties of high-strength high-volume ground granulated blast-furnace slag (GGBFS) blended cement concrete, this study investigated the rheology, strength development, hydration and pozzolanic reaction characteristics, porosity and pore size distribution of high-strength mortars with the water-to-binder ratio of 20, 50 to 80% GGBFS, up to 20% limestone powder, and up to 10% silica fume. According to test results, compared with the Portland cement mixture, the high-volume GGBFS mixture had much higher flow due to the low surface friction of GGBFS particles and higher strength in the early age due to the accelerated cement hydration by increase of free water; however, because of too low water-to-binder ratio and cement content, and lack of calcium hydroxide content, the pozzolanic reactio cannot be activated and the long-term strength development was limited. Limestone powder did not affect the flowability, and also accelerate the early cement hydration. However, because its effect on the acceleration of cement hydration is not greater than that of GGBFS, and it does not have hydraulic reactivity unlikely to GGBFS, compressive strength was reduced proportional to the replacement ratio of limestone powder. Also, silica fume and very fine GGBFS lowered flow and strength by absorbing more free water required for cement hydration. Capillary porosities of GGBFS blended mortars were smaller than that of OPC mortar, but the effect of limestone powder on porosity was not noticeable, and silica fume increased porosity due to low degree of hydration. Nevertheless, it is confirmed that the addition of GGBFS and silica fume increases fine pores.