• 대한임상독성학회지
• /
• 제18권2호
• /
• pp.51-56
• /
• 2020

Purpose: Acute nicotine poisoning by liquid nicotine in electronic cigarettes is becoming an increasing problem worldwide. The current systematic review aimed to determine the harm of acute nicotine poisoning by reviewing published case reports. Methods: An online literature search with PubMed, Embase, Cochrane Library, and KoreaMed database was performed to identify relevant studies addressing acute nicotine poisoning with electronic cigarettes. Two investigators searched the case reports written in English or Korean. Results: Twenty-six cases were included in this study. The routes of intoxication included ingestion in 18 cases, intravenous injection in three cases, subcutaneous injection in two cases, and ocular exposure in two cases. Ten cases had a cardiac arrest, and seven of them died. Seven out of 12 cases with intentional poisoning had a cardiac arrest. Nine children under 18 years were reported, and three of them had a cardiac arrest. Sixteen cases without a cardiac arrest recovered well, except for one case with sudden sensorineural hearing loss. Conclusion: The authors reviewed the risks of electronic cigarette liquid in terms of acute poisoning through a systematic review. The nicotine solution of an e-cigarette can be life-threatening in cases of acute poisoning. Therefore, active emergency treatment with early recognition is necessary. In addition, various management methods and regulations for preventing acute nicotine poisoning, such as restriction of distribution and nicotine concentration, should be considered.

• International Journal of Computer Science & Network Security
• /
• 제21권1호
• /
• pp.12-18
• /
• 2021

This paper proposes a framework for the development of the health recommender system, designed to cater COVID-19 symptoms' self-assessment and monitoring as well as to provide recommendations for self-care and medical treatments. The aim is to provide an online platform for Patient Under Investigation (PUI) and close contacts with positive COVID-19 cases in Malaysia who are under home quarantine to perform daily self-assessment in order to monitor their own symptoms' development. To achieve this, three main phases of research methods have been conducted where interviews have been done to thirty former COVID-19 patients in order to investigate the symptoms and practices conducted by the Malaysia Ministry of Health (MOH) in assessing and monitoring COVID-19 patients who were under home quarantine. From the interviews, an algorithm using user-based collaborative filtering technique with Pearson correlation coefficient similarity measure is designed to cater the self-assessment and symptoms monitoring as well as providing recommendations for self-care treatments as well as medical interventions if the symptoms worsen during the 14-days quarantine. The proposed framework will involve the development of the health recommender system for COVID-19 self-assessment and treatments using the progressive web application method with cloud database and PHP codes.

• 품질경영학회지
• /
• 제48권4호
• /
• pp.567-580
• /
• 2020

Purpose: The purpose of this study is to present a preferred parts list, establish a search tool for common parts, and propose a development plan for parts management. Methods: When selecting the preferred parts list, the weight of the selection of the military parts and the online site of the civilian parts were taken into account. By establishing a database of selected preferred parts list, we have established a system for searching common parts. Results: The results of this study are as follows; In order to establish parts management work in Korea's defense, it is necessary to improve the Defense Acquisition Program Act, Enforcement Decree (Rules), and the Regulations for Defense Acquisition Program Administration. Development of performance indicators for parts management is required, and establishment of procedures and standards for selection of preferred parts lists is required. Considerations for the selection of preferred parts list include whether they are used a lot in civilian products, whether they are used a lot, whether they are certified suppliers, whether they are national and industrial standard products, whether they perform well considering reliability, durability, and quality, and whether they can be supplied continuously. Conclusion: It is necessary to establish policies and systems related to parts management and to establish criteria for selecting preferred parts list for the development of domestic parts management tasks.

• 한국기록관리학회지
• /
• 제22권1호
• /
• pp.237-243
• /
• 2022

성북마을아카이브는 성북구청과 성북문화원이 협력하여 지역의 고유성과 특수성을 담고자 구축한 마을아카이브이다. 공동체의 기록물을 보존하는 공동체 아카이브이자, 원천자료의 디지털화를 통해 데이터베이스를 구축해가는 디지털 아카이브이다. 민·관 거버넌스로 연차적·단계별 추진을 거쳐 관리시스템과 홈페이지를 구축하였다. 성북마을아카이브의 시스템은 고도화된 마을기록 표준분류체계를 바탕으로 자료축적과 개별 기록물 간의 연결이 원활히 이루어지도록 설계되었다. 성북문화원은 이를 바탕으로 기록물을 온·오프라인으로 연계하면서 융합문화콘텐츠를 생산하려고 노력하였다. 또한 기록물의 보존뿐 아니라 콘텐츠 생산 및 활용을 위해 홈페이지에 보여지는 항목 구성을 다양화했다. 성북의 역사문화자원을 어떻게 하면 이용자들에게 그 생성 및 존재를 맥락과 함께 보여줄 수 있을지에 대한 고민 끝에 만든 구조이다. 또한 다채로운 큐레이션과 주민기록단의 활동을 통해 보다 풍부한 아카이브 플랫폼을 구축하였다.

• Journal of Periodontal and Implant Science
• /
• 제52권5호
• /
• pp.352-369
• /
• 2022

The aim of this systematic review was to evaluate clinical and microbiological outcomes with the use of azithromycin as an adjunct to non-surgical subgingival professional mechanical plaque removal (PMPR) in the treatment of grade C periodontitis. Online database searches using high-level MeSH terms in a PICO structure were conducted along with hand-searching of relevant periodontal journals. Titles and abstracts of identified studies were independently reviewed by both authors and the full texts of studies meeting the inclusion criteria were independently reviewed. In total, 122 studies were identified through searches, of which 6 were included in the qualitative analysis and 4 in the meta-analysis. Three studies included in the meta-analysis were deemed at low risk of bias and 1 at serious risk. There were conflicting results on whether azithromycin reduced the number of subgingival pathogens or detectable subgingival Aggregatibacter actinomycetemcomitans between the included studies. The meta-analysis revealed a statistically significant probing depth reduction difference in favour of azithromycin compared to the control at 3 months (weighted mean difference [WMD]=-0.39 mm; 95% confidence interval [CI], -0.66 to -0.13 mm; I²=0%) and 12 months (WMD=-1.32 mm; 95% CI, -1.71 to -0.93 mm; I²=0%). The clinical attachment level change was also statistically significant in favour of azithromycin compared to the control at 3 months (WMD=-0.61 mm; 95% CI, -1.13 to -0.10 mm; I²=71%) and 12 months (WMD=-0.88 mm; 95% CI, -1.32 to -0.44 mm; I²=0%). Based upon these results, azithromycin offers additional improvements in some clinical parameters when used in conjunction with subgingival PMPR in patients with aggressive periodontitis over control groups. These improvements appear to be maintained for up to 12 months after treatment completion. However, due to a lack of well-designed studies, the conclusions that can be drawn from the available evidence are limited.

• 천문학회지
• /
• 제55권4호
• /
• pp.111-121
• /
• 2022

Based on the light an exoplanet blocks from its host star as it passes in front of it during a transit, the mid-transit time can be determined. Periodic variations in mid-transit times can indicate another planet's gravitational influence. We investigate 83 transits of TrES-1 b as observed from 6-inch telescopes in the MicroObservatory robotic telescope network. The EXOTIC data reduction pipeline is used to process these transits, fit transit models to light curves, and calculate transit midpoints. This paper details the methodology for analyzing transit timing variations (TTVs) and using transit measurements to maintain ephemerides. The application of Lomb-Scargle period analysis for studying the plausibility of TTVs is explained. The analysis of the resultant TTVs from 46 transits from MicroObservatory and 47 transits from archival data in the Exoplanet Transit Database indicated the possible existence of other planets affecting the orbit of TrES-1 and improved the precision of the ephemeris by one order of magnitude. We now estimate the ephemeris to be (2 455 489.66026 BJD_TDB ± 0.00044 d) + (3.0300689 ± 0.0000007) d × epoch. This analysis also demonstrates the role of small telescopes in making precise midtransit time measurements, which can be used to help maintain ephemerides and perform TTV analysis. The maintenance of ephemerides allows for an increased ability to optimize telescope time on large ground-based telescopes and space telescope missions.

• Genomics & Informatics
• /
• 제20권3호
• /
• pp.31.1-31.15
• /
• 2022

A pandemic of respiratory disease named coronavirus disease 2019 (COVID-19) is caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It is reported prostate cancer patients are susceptible to COVID-19 infection. To understand the possible causes of prostate cancer patients' increased vulnerability and mortality from COVID-19 infection, we focused on the two most important agents, transmembrane protease serine subtype 2 (TMPRSS2) and the C-X-C motif 10 (CXCL10). When SARS-CoV-2 binds to the host cell via S protein-angiotensin-converting enzyme-2 receptor interaction, TMPRSS2 contributes in the proteolytic cleavage of the S protein, allowing the viral and cellular membranes to fuse. CXCL10 is a cytokine found in elevated level in both COVID-19 and cancer-causing cytokine storm. We discovered that TMPRSS2 and CXCL10 are overexpressed in prostate cancer and COVID-19 using the UALCAN and GEPIA2 datasets. The functional importance of TMPRSS2 and CXCL10 in prostate cancer development was then determined by analyzing the frequency of genetic changes in their amino acid sequences using the cBioPortal online portal. Finally, we used the PANTHER database to examine the pathology of the targeted genes. We observed that TMPRSS2 and CXCL10, together with their often co-expressed genes, are important in the binding activity and immune responses in prostate cancer and COVID-19 infection, respectively. Finally, we found that TMPRSS2 and CXCL10 are two putative biomarkers responsible for the increased vulnerability and fatality of prostate cancer patients to COVID-19.

• 중소기업연구
• /
• 제42권3호
• /
• pp.43-75
• /
• 2020

본 연구는 중소기업학회에서 편찬한 '중소기업연구'에 게재된 논문을 분석하여 사업실패의 연구동향을 알아보는데 있다. 이를 위하여, 첫째, 문헌고찰을 통해, 해외의 연구동향과 주요 연구 주제를 탐색하고, 본 연구를 위한 분석의 틀을 작성하였다. 둘째, 1979년부터 2019년에 이르기까지, 중소기업연구에 편찬된 총 1,060편의 논문 중, 실패와 관련된 16편을 선정하고 분석하였다. 세 번째, 중소기업연구 이외의 한국의 실패 연구동향을 알아보기 위해, 키워드 분석으로 24편을 추가로 선정하여 분석하였다. 본 논문에서는 실패 연구의 동향을 총 5가지 큰 주제로 구분하여 분석하였다. (1) 실패예측, (2) 실패 전·후 감정, (3) 감정 이외 실패 비용, (4) 실패 원인, (5) 재창업 결정 및 성공요인이다. 기존연구가 가지는 함의를 살펴봄으로써, 향후 실패분야의 연구방향을 제시하고 있다.

• 한국콘텐츠학회논문지
• /
• 제21권11호
• /
• pp.64-76
• /
• 2021

디지털기술융합사회에서 문화기술의 중요도가 커지고 있지만, 이에 비해 문화기술의 동향을 정확하게 파악하고 분석하고자 하는 시도가 부족한 실정이다. 특히 문화기술의 경우 국가 차원에서 주도하여 발전해 왔으며, 이에 문화기술을 분석함에 있어 국가적 관점을 견지하는 것이 매우 중요하다. 따라서 본 연구는 국가연구과제를 바탕으로 문화기술 동향을 분석하고 향후 문화기술 발전에 대한 시사점을 제공하는 데 초점을 맞추었다. 본 연구는 국가과학기술정보서비스(NTIS)에서 문화기술 연구과제 데이터를 수집하여 연구내용에 대한 키워드 네트워크를 분석하고, 군집분석을 통해 문화기술 과제를 유형화하고 그 특성을 분석하였다. 분석 결과 문화기술은 정보지식에서 디지털콘텐츠, 문화미디어로 발전하고 최근 머신러닝 기술에 접목하여 활발하게 활용되고 있는 것으로 나타났다. 최근에는 코로나19의 사회적 환경의 변화로 비대면 온라인 콘텐츠에 대한 수요로 AR, VR 등 다양한 문화산업에 대한 연구로 발전하고 있는 것을 확인하였다. 이를 통해 본 연구는 문화기술을 이해하고 그 동향을 분석하여, 문화기술의 혁신 가능성을 확인하기 위한 중요한 단서를 제공하였다.

• 한국인터넷방송통신학회논문지
• /
• 제22권4호
• /
• pp.165-170
• /
• 2022

외부에서 보내는 시간을 줄이고 동네마트를 주로 이용하는 중년층, 노년층들과 동네마트 관리자들을 위한 장보기 시스템을 개발하였다. 이 앱은 직접 장보기 기능과 온라인 장보기 기능이 주요 기능이며 안드로이드에서 Zxing라이브러리를 이용한 QR코드와 카카오 API를 이용한 카카오맵을 이용해 개발되었다. 또한 리사이클러뷰와 그래프를 통해 회원이 필요로 하는 결제 통계와 게시판 글 등의 정보를 가독성 있게 제공한다. 이 시스템을 통해 회원들은 QR코드를 이용한 직접구매 방식과 지도를 통한 배달 방식을 통해 마트를 이용할 때의 피로감을 줄이고 마트 관리자로서는 인력낭비를 줄임으로서 효율적으로 관리할 수 있다. 또한 마트 관리자로서는 소비자들이 늘어나 더 많은 물품을 판매할 수 있을 것이다.