• Title/Summary/Keyword: One-Step

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Simplification of One Step Immunotech AFP Test (AFP 검사방법 단축에 관한 고찰)

  • Moon, Ki Choon;Kwon, Won Hyun;Kim, Jung In;Lee, In Won
    • The Korean Journal of Nuclear Medicine Technology
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    • v.17 no.1
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    • pp.80-84
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    • 2013
  • Purpose: The Immunotech AFP is a widely used test in 14 hospitals(RIA QC establishments: 46) as a liver tumor marker. Normally, the test takes 45 minutes including complicated 2 step method. We evaluated the possibility of 1 step method and suitable test time. Materials and Methods: Samples of 31 patients in SNUBH were used as subject. We evaluated the sensitivity, intra and inter assay precision, recovery rate, linearity between 1 step and 2 step method (45 min. and 60 min.). Results: Both of 45 minutes and 60 minutes test showed 0.1 ng/mL sensitivity. In 45 minutes test, the intra assay coefficients of variation were 3.05%, 3.43%, 1.68%. Also, inter assay coefficients of variation were 3.91%, 2.38%, 0.82%. In 60 minutes test, the intra assay were 5.00%, 3.69%, 1.97%, inter assay were 3.14%, 3.71%, 1.85%.The correlation coefficient of each 2 step and 1 step (45 min.), 2 step and 1 step(60 min.), 1 step (45 min.) and 1 step (60 min.) were y=0.9293x+2.7356 ($R^{2}=0.9999$), y=0.9193x+4.1002 ($R^{2}=0.9993$), y=0.9894x+1.3805 ($R^{2}=0.9997$). Conclusion: Compared 1step method to 2 step method, both method showed very reasonable precision, recovery rate and correlation coefficient. Also, 1 step method(45 min.) of correlation coefficient ($R^2$) was 0.999. We suggest that 1 step method test can reduce the test time and is useful for AFP test.

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Multi-step design optimization of a high speed machine tool structure using a genetic algorithm with dynamic penalty (동적 벌점함수 유전 알고리즘과 다단계 설계방법을 이용한 공작기계 구조물의 설계 최적화)

  • 최영휴;배병태;김태형;박보선
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2002.05a
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    • pp.108-113
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    • 2002
  • This paper presents a multi-step structural design optimization method fur machine tool structures using a genetic algorithm with dynamic penalty. The first step is a sectional topology optimization, which is to determine the best sectional construction that minimize the structural weight and the compliance responses subjected to some constraints. The second step is a static design optimization, in which the weight and the static compliance response are minimized under some dimensional and safety constraints. The third step is a dynamic design optimization, where the weight static compliance, and dynamic compliance of the structure are minimized under the same constraints. The proposed design method was examined on the 10-bar truss problem of topology and sizing optimization. And the results showed that our solution is better than or just about the same as the best one of the previous researches. Furthermore, we applied this method to the topology and sizing optimization of a crossbeam slider for a high-speed machining center. The topology optimization result gives the best desirable cross-section shape whose weight was reduced by 38.8% than the original configuration. The subsequent static and dynamic design optimization reduced the weight, static and dynamic compliances by 5.7 %, 2.1% and 19.1% respectively from the topology-optimized model. The examples demonstrated the feasibility of the suggested design optimization method.

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Design of a High Performance Two-Step SOVA Decoder (고성능 Two-Step SOVA 복호기 설계)

  • 전덕수
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.7 no.3
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    • pp.384-389
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    • 2003
  • A new two-step soft-output Viterbi algorithm (SOVA) decoder architecture is presented. A significant reduction in the decoding latency can be achieved through the use of the dual-port RAM in the survivor memory structure of the trace-back unit. The system complexity can be lowered due to the determination of the absolute value of the path metric differences inside the add-compare-select (ACS) unit. The proposed SOVA architecture was verified successfully by the functional simulation of Verilog HDL modeling and the FPGA prototyping. The SOVA decoder achieves a data rate very close to that of the conventional Viterbi Algorithm (VA) decoder and the resource consumption of the realized SOVA decoder is only one and a half times larger than that of the conventional VA decoder.

Study on Measurement Error Reduction Technique when Measuring Touch and Step Voltage of Grounding System (접지시스템의 접촉전압 및 보폭전압 측정오차 감소 기법에 관한 연구)

  • Kim, Dong-Woo;Lim, Young-Bea;Lee, Sang-Ick;Choi, Myeong-Il;Moon, Hyun-Wook
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.64 no.1
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    • pp.188-195
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    • 2015
  • This paper presents measurement error reduction technique of touch and step voltage of grounding system based on numerical analysis. When measuring touch and step voltage of grounding system, auxiliary current probes should be located at suitable places. However, the auxiliary probes can not be located at suitable places in such cases as there are buildings and pavements. Therefore, in this paper, we provided measurement error reduction technique of touch and step voltage of grounding system according to the positions of auxiliary probes and angle between auxiliary probes. Also, measurement error analyses of touch and step voltage of grounding system have been conducted using more than one current probe. Based on these analyses, recommended positions of auxiliary probes within allowable measurement errors were presented.

On the natural frequencies and mode shapes of a multiple-step beam carrying a number of intermediate lumped masses and rotary inertias

  • Lin, Hsien-Yuan;Tsai, Ying-Chien
    • Structural Engineering and Mechanics
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    • v.22 no.6
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    • pp.701-717
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    • 2006
  • In the existing reports regarding free transverse vibrations of the Euler-Bernoulli beams, most of them studied a uniform beam carrying various concentrated elements (such as point masses, rotary inertias, linear springs, rotational springs, spring-mass systems, ${\ldots}$, etc.) or a stepped beam with one to three step changes in cross-sections but without any attachments. The purpose of this paper is to utilize the numerical assembly method (NAM) to determine the exact natural frequencies and mode shapes of the multiple-step Euler-Bernoulli beams carrying a number of lumped masses and rotary inertias. First, the coefficient matrices for an intermediate lumped mass (and rotary inertia), left-end support and right-end support of a multiple-step beam are derived. Next, the overall coefficient matrix for the whole vibrating system is obtained using the numerical assembly technique of the conventional finite element method (FEM). Finally, the exact natural frequencies and the associated mode shapes of the vibrating system are determined by equating the determinant of the last overall coefficient matrix to zero and substituting the corresponding values of integration constants into the associated eigenfunctions, respectively. The effects of distribution of lumped masses and rotary inertias on the dynamic characteristics of the multiple-step beam are also studied.

A Study on the Step Response Model Development of a Dynamic Matrix Control(DMC) For Boiler-Turbine Systems in a Fossil Power Plant (화력발전 보일러-터빈 시스템을 위한 Dynamic Matrix Control(DMC)의 계단응답모델 선정에 관한 연구)

  • Moon, Un-Chul
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.20 no.5
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    • pp.125-133
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    • 2006
  • This paper presents comparison results of Step Response Model of Dynamic Matrix Control(DMC) for a drum-type boiler-turbine system of a fossil power plant. Two possible kinds of step response models are investigated in designing the DMC, one is developed with the linearization of theoretical model and the other is developed with the process step-test data. Then, the control performances of each model-based DMC are simulated and evaluated. It is observed that the simulation results with the step-response model based on the test data show satisfactory results, while the linearized model is not suitable for the control of boiler-turbine system.

Experimental study on flow field behind backward-facing step using detonation-driven shock tunnel

  • Kim, T.H.;Yoshikawa, M.;Narita, M.;Obara, T.;Ohyagi, S.
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2004.03a
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    • pp.85-92
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    • 2004
  • As a research to develop a SCRAM jet engine is actively conducted, a necessity to produce a high-enthalpy flow in a laboratory is increasing. In order to develop the SCRAM-jet engine, stabilized combustion in a supersonic flow-field should be attained, in which a duration time of flow is extremely short. Therefore, a mixing process of breathed air and fuel, which is injected into supersonic flow-fields is one of the most important problem. Since, the flow inside SCRAM jet engine has high-enthalpy, an experimental facility is required to produce such high-enthalpy flow-field. In this study, a detonation-driven shock tunnel was built and was used to produce high-enthalpy flow. Further-more, SCRAM jet engine model equipped backward-facing step was installed at test section and flow-fields were visualized using color-schlieren technique and high speed video camera. The fuel was injected perpendicular to the flow of Mach number three behind backward-facing step. The height of the step, distance of injection and injection pressure were changed to investigate the effects of step on a mixing characteristic between air and fuel. The schlieren photograph and pressure histories show that the fuel was ignited behind the step.

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A Study on Measurement of Repetitive Work using Digital Image Processing (영상처리를 이용한 반복적 작업의 측정에 관한 연구)

  • Lee, Jeong-Cheol;Sim, Eok-Su;Kim, Nam-Joo;Park, Chan-Kwon;Park, Jin-Woo
    • IE interfaces
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    • v.14 no.1
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    • pp.95-105
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    • 2001
  • Previous work measurement methods need much time and effort of time study analysts because they have to measure required time through direct observations. In this study, we propose a method which efficiently measures standard times without involvement of human analysts using digital image processing techniques. This method consists of two main steps: motion representation step and cycle segmentation step. In motion representation step, we first detect the motion of any object distinct from its background by differencing two consecutive images separated by a constant time interval. The images thus obtained then pass through an edge detector filter. Finally, the mean values of coordinates of significant pixels of the edge image are obtained. Through these processes, the motions of the observed worker are represented by two time series data of worker location in horizontal and vertical axes. In the second step, called the cycle segmentation step, we extract the frames which have maximum or minimum coordinates in one cycle and store them in a stack, and calculate each cycle time using these frames. In this step we also consider methods on how to detect work delays due to unexpected events such as operator's escapement from the work area, or interruptions. To condude, the experimental results show that the proposed method is very cost-effective and useful for measuring time standards for various work environment.

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Development of a Pneumatic Servomechanism Using a Direct-connected Circuit between Inlet and Outlet and Its Application to the Design of a Fuzzy Position Controller for a Fingering System (흡배기구 직결회로를 이용한 공압 서보장치의 개발과 집게 시스템용 퍼지제어기 설계)

  • Choi, Kap-Yong;Choi, In-Soo
    • Journal of Korean Institute of Industrial Engineers
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    • v.21 no.4
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    • pp.593-608
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    • 1995
  • In this study two issues are considered, one is to develop a pneumatic servomechanism using a direct-connected circuit between inlet and outlet, the other is to design two kinds of advanced controllers such as fuzzy and PID controllers for a fingering system. Besides, the application of the advanced controllers to the newly proposed servomechanism is presented. The procedure of this study is composed of following 6 steps : [Step 1] Structuring of a control system; [Step 2] Development of a pneumatic circuit for the servomechanism ; [Step 3] Characteristic analysis of the valve and cylinder systems ; [Step 4] Determination of optimal parameters of the PID controller ; [Step 5] Design of a fuzzy controller and parameter tuning; and, [Step 6] Experimental analysis of fuzzy and PID controllers. Experimental results show that the newly proposed pneumatic servomechanism has good performance and, not only the performance of the fuzzy controller is better than that of the PID controller but also the fuzzy controller fits well to the control of the pneumatic servomechanism.

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Two-Step Etching Characteristics of Single-Si by the Plasma Etching Techique (플라즈마 식각방법에 의한 단결정 실리콘의 Two-Step 식각특성)

  • Lee, Jin Hee;Park, Sung Ho;Kim, Mal Moon;Park, Sin Chong
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.24 no.1
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    • pp.91-96
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    • 1987
  • Plasma etching can obtain less damaged etch surface than reactive ion etching. This study was performed to get anisotropic etching characteristics of Si using two step etching technique with C2CIF5 and SF6 gas mixture. The results show that the etch rate and aspect ratio of silicon was increased with increment of SF6 contents. The bulging phenomenon on trench side wall in the plasma one-step etching technique was eliminated by the two step etching technique. The anisotropy was decreased from 12(at 120m Torr) to 2.2(at 400m Torr) with increasing the chamber pressure. At the low rf power (350 watts) anisotrpy of silicon was obtained 7 lower than that of high rf power (650 watts. A:~9). In Summary we obtained anisotropic etching profiles of silicon with e 6\ulcornerm depth by using the plasma two-step etching technique.

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