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ANNIHILATORS IN ONE-SIDED IDEALS GENERATED BY COEFFICIENTS OF ZERO-DIVIDING POLYNOMIALS

  • Kwak, Tai Keun;Lee, Dong Su;Lee, Yang
    • Journal of the Korean Mathematical Society
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    • v.51 no.3
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    • pp.495-507
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    • 2014
  • Nielsen and Rege-Chhawchharia called a ring R right McCoy if given nonzero polynomials f(x), g(x) over R with f(x)g(x) = 0, there exists a nonzero element r ${\in}$ R with f(x)r = 0. Hong et al. called a ring R strongly right McCoy if given nonzero polynomials f(x), g(x) over R with f(x)g(x) = 0, f(x)r = 0 for some nonzero r in the right ideal of R generated by the coefficients of g(x). Subsequently, Kim et al. observed similar conditions on linear polynomials by finding nonzero r's in various kinds of one-sided ideals generated by coefficients. But almost all results obtained by Kim et al. are concerned with the case of products of linear polynomials. In this paper we examine the nonzero annihilators in the products of general polynomials.

An efficient blood testing procedurer by using group testing (그룹 검사를 이용한 효율적인 혈액 검사 절차에 대한 연구)

  • 양원석;채경철
    • The Korean Journal of Applied Statistics
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    • v.9 no.1
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    • pp.17-29
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    • 1996
  • Suppose we have g itesm classified as defective or as nondefective. If we test each item separately, then g tests are required. However, it is possible to test a group of g items so as to detect whether at least one of them is defective, and to proceed to individual testing only if the presense of at least one defective item is indicated. The method is called Dorfman procedure. In this paper, we consider a variant of Dorfman procedure called a hierarchal dorfman procedure. We also consider the curtailment effect resulted from the dependency of the tests. We propose an efficient blood testing procedure. We also present ot heuristic rule of thumb which is simple and easily implementable.

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Polyubiquitin-Proteasomal Degradation of Leucine-Rich Repeat Kinase 2 Wildtype and G2019S

  • Park, Sangwook
    • Biomedical Science Letters
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    • v.27 no.3
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    • pp.182-186
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    • 2021
  • Parkinson disease (PD) is becoming one of the most neurodegenerative disorder worldwide. The deposited aggregates have been connected in the pathophysiology of PD, which are degraded either by ubiquitin-proteasomal system (UPS) or autophagy-lysosomal pathway (ALP). Leucin-rich repeat kinase 2 (LRRK2), one of the neurodegenerative proteins of PD is also stringently controlled by both UPS and ALP degradation as well. However, the polyubiquitination pattern of LRRK2 aggregates is largely unknown. Here, we found that K63-linked polyubiquitinations of G2019S mutant, most familial variant for PD, is highly enhanced compared to those of wild type LRRK2 (WT). In addition, in the presence of overexpressed p62/SQSTM-1, ubiquitination of LRRK2 WT or D1994A was reduced, whereas G2019S mutant was not diminished significantly. Therefore, we propose that degradation of G2019S via UPS is more involved with K63-linked ubiquitination than K48-linked ubiquitination, and overexpressed p62/SQSTM-1 does not enhance degradative effect on G2019S variant.

Isolation and Development of Quantitative Determination of Torilin from the Torilis Fructus (사상자 (Torilis Fructus)의 지표성분으로 Torilin의 분리 및 함량분석법 개발)

  • Hwang, Eui-Il;Lee, Seong-Kye;So, Seung-Ho;Koo, Bon-Suk;Han, Gyeong-Ho;Kim, Na-Mi
    • Korean Journal of Pharmacognosy
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    • v.38 no.4
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    • pp.321-326
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    • 2007
  • For the propose of the quality control of Torilis Fructus, one major compound was isolated by several column chromatograpies and identified by its spectral data as torilin (8,11-dihydroxy-8-angeloyl-11-acetyl-4-guaien-3-one). A quantitative analysis of torilin using HPLC method showed that the average contents at 230 and 254 nm were $7.167{\pm}0.168mg/g\;and\;7.052{\pm}0.160mg/g$, respectively, in 18 samples collected throughout the regions of Korea and China. This method provided a tool for standardization of the commercial Torilis Fructus.

Nitrites contents on processed meat products(ham, sausage etc) in market during 2000-2003 (시판 식육가공품(햄류, 소시지류 등)에 대한 최근 4년간(2000-2003) 아질산이온 함량)

  • 함희진;홍인석;임홍규;양윤모;최윤화;김창기;권택부;이정학
    • Korean Journal of Veterinary Service
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    • v.27 no.2
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    • pp.115-120
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    • 2004
  • Contents of nitrites was tested in 2,290 meat products during 2000-2003, in Seoul by Diazoa method. It was detected over 40 ppm NO$_2$$\^$-/ contents in 20 hams, 7 sausages, one bacon, and one crushed meat product respectively. Also, over 20ppm nitrites was 21.8%(240/1,103) in hams, 20.7%(122/589) in sausages, 6.8%(14/205) in crushed meats, and in 6.0%(5/83) bacons respectively. In case of average contents and contents range, 0.012 g/kg, ND-0.116 g/kg in hams, 0.012 g/kg, ND-0.066 g/kg in sausages, 0.010 g/kg, 0.001-0.089 g/kg in bacons, and 0.006 g/kg, ND-0.040 g/kg in crushed meats etc. Specially, in sausages, it was increased continually by years, in not only average nitrites contents but also their contents range, also, in case of bacons, increased continually by years on only average nitrites contents. According to results, the NO$_2$$\^$-/ contents monitoring for the processed meat products must be reinforced to supply safety food for the citizens.

Production and Characteriuation of Monoclonal Antibodies against Human Interferon-$\alpha$ (인터페론 알파에 대한 단세포 군항체의 제조 및 특성)

  • Park, Kyung-Hee;Lee, Ihn-Sook
    • The Korean Journal of Zoology
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    • v.35 no.1
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    • pp.1-7
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    • 1992
  • Seven monoclonal antibodies were produced by fusing splenocytes from Balb/C mouse immunized with partially purified human interferon-a (HUIFN-a) with NSO plasmacytoma cells. aery were identified as five IgG class (432.22: IgG2b/n, 460.52: IgG2b/a , 548.46: IgG2a/n , 573.10: IgG2b/h , 625.12: IgG2b/n ), one IgA class (460.50: IgA/n ) and one IsM class (465.27: IgA/n ), and all of them revealed highly sensitive to HUIFN- a IgG class monoclonal antibodies have pts ranged from 8.2 to 8.6. Ascites fluids produced from primed Balb/c mice and were purified through column chromatography. The cytopathic effect (CPE) inhibition assay to examine neutralization of HuIFU-a by IgG class monoclonal antibodies, gave that MAbs 460.52, 548.46, 573.10 can neutralize HUIFU- a arith varying degrees except 432.22. Therefore, it is deduced that these various monoclonal antibodies may recognize the distinct epitopes on HUIFN-a.

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A Performance Analysis Model of PC-based Software Router Supporting IPv6-IPv4 Translation for Residential Gateway

  • Seo, Ssang-Hee;Kong, In-Yeup
    • Journal of Information Processing Systems
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    • v.1 no.1 s.1
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    • pp.62-69
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    • 2005
  • This paper presents a queuing analysis model of a PC-based software router supporting IPv6-IPv4 translation for residential gateway. The proposed models are M/G/1/K or MMPP-2/G/1/K by arrival process of the software PC router. M/G/1/K is a model of normal traffic and MMPP-2/G/1/K is a model of burst traffic. In M/G/1/K, the arriving process is assumed to be a Poisson process, which is independent and identically distributed. In MMPP-2/G/1/K, the arriving process is assumed to be two-state Markov Modulated Poisson Process (MMPP) which is changed from one state to another state with intensity. The service time distribution is general distribution and the service discipline of the server is processor sharing. Also, the total number of packets that can be processed at one time is limited to K. We obtain performance metrics of PC-based software router for residential gateway such as system sojourn time blocking probability and throughput based on the proposed model. Compared to other models, our model is simpler and it is easier to estimate model parameters. Validation results show that the model estimates the performance of the target system.

Volatile Substances and Physicochemical Characteristics of Pyroligneous Liquor (목초액의 휘발성 성분과 이화학적 특성)

  • Kim Jong-Soo;Park Seung-Woo;Choi Jung-Hwan;Lee Eun-Young;Lee Sang-Han;Chung Shin-Kyo
    • Food Science and Preservation
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    • v.12 no.6
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    • pp.656-661
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    • 2005
  • To develop food additives from pyroligneous liquor, we first examined the physicochemical characteristics of volatile substances. The pH, gravity, acidity, solution tar, and scorched remains in the pyroligneous liquor were 2.50, 1.020, $0.8\%$ $2.31\%$ and $0.008\%$ respectively. The main compounds of pyroligneous liquor were 2,6-dimethoxyphenol (syringol), 2-hydroxy-2-cyclopenten-l-one, 1,2-benzenediol (catechol), phenol, 2 (5H)-furanone, 2-methoxyphenol (guaiacol), 5-hydroxymethyl-2 furancarboxaldehyde were found in organic phase, whereas catechol, 1,4 : 3,6-dianhydro-${\alpha}d$-glucopyranose, cyclopropyl carbinol, 5-hydroxymethyl-2 furancarboxaldehyde in aqueous phase.

Improvement of Alcohol Productivity by Means of Repeated Batch Fermentation (반복적인 회분식 발효공정을 이용한 에탄올 생산성의 향상)

  • 김휘동;민경호허병기
    • KSBB Journal
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    • v.10 no.1
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    • pp.55-62
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    • 1995
  • The functional relationship between the initial cell concentration and the ethanol productivity was investigated in the repeated batch fermentation of Sacharomyces cerevisiae ATCC 24858. The repeated batch fermentations were performed in the range of 60 to $150g/\ell$ of initial sugar concentration and 17.5g/$\ell$ to $53.1g/\ell$ of initial cell concentration. The time of one batch fermentation was 1 or 2 hours and the batch fermentation was repeated ten times in every repeated formentaction. The functional relationship showed that the productivity increased non-linearly according to the increase of initial cell concentration regardless of initial sugar concentration. When the initial concentration of sugar was $60g/\ell$ and that of biomass was $34.5g/\ell$, the fermentation was completed within one hour and its ethanol productivity was $26.7g/\ell$.hr, the latter including the times of cell separation, pouring the new substrate into a flask and sampling. When the initial sugar concentration was $120g/\ell$ and the initial cell concentration $50.3g/\ell$, the fermentation was also finished within one hour and its productivity was $45.8g/\ell$$.$hr, The maximum ethanol productivity for eight different repealed fermentations in this work was $53g/\ell$.hr.

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Usage Patterns of Feminine Hygiene Products and Preservative Contents in Feminine Cleansers in the Korean Market (국내 판매중인 여성청결제의 사용실태 및 함유 보존제 분석)

  • Kim, Wanseo;Youn, Youngin;Lee, Gowoon;Park, Na-Youn;Kho, Younglim;Choi, Kyungho
    • Journal of Environmental Health Sciences
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    • v.44 no.2
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    • pp.115-123
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    • 2018
  • Objectives: Preservatives, suspected to be endocrine disrupting chemicals, are widely used in feminine hygiene products for the prevention of deterioration. Information regarding the usage patterns of feminine hygiene products and the concentrations of preservatives in these products is limited. The present study was conducted to investigate the use of feminine cleansers among Korean women and quantify the concentration of preservatives in feminine cleansers. Methods: Approximately 500 women were recruited from the city of Busan in August 2017 and a questionnaire survey was conducted on the use of feminine cleansers. Several major feminine hygiene products (n=69) were identified and selected for analysis of 22 preservatives. Following appropriate preparation, the products were analyzed by HPLC/DAD. Results: Over 70% of the participating women used at least one feminine cleanser. Marital status and parity were associated with the frequency of use. Liquid was most frequently used form of feminine cleanser (66.6%). The greatest proportion of subjects answered that they use it 'one to two times per week' (36.5%). Among the 69 feminine cleansers, benzoic acid, sorbic acid, phenoxyethanol, and methyl paraben were detected at $144-4,428{\mu}g/g$, $195-1,470{\mu}g/g$, $269-4,237{\mu}g/g$, and $625-4,901{\mu}g/g$, respectively. BA was the most frequently detected (46.4%). Conclusions: In the present study, the characteristics of feminine cleanser use among Korean women were investigated. Based on an analysis of preservatives in the feminine hygiene products, one product was determined to exceed the maximum authorized concentration of MeP (0.4%). Our results will help refine exposure and risk assessment for toxic chemicals in feminine cleansers.