• Journal of Acupuncture Research
• /
• 제26권5호
• /
• pp.49-56
• /
• 2009

Objectives : The purpose of this study was to assess the effect of Hwangryunhaedok-tang pharmacopuncture at $CV_{17}$ for reducing mental stress using power spectrum analysis of the heart rate variability(HRV). Methods : 30 healthy volunteers(control group: 15, experimental group: 15) participated in this study. After instrumentation and 5-minutes rest period, mental stress by operation was provided for 5-minutes. HRV was recorded before and after the mental stress. And then the control group rested for 15-minutes. The experimental group was injected Hwangryunhaedok-tang pharmacopuncture at $CV_{17}$ and rested for 15-minutes. And then HRV was recorded. Results : In simple rest group, LF norm and HF norm showed a significant change after mental stress. In pharmacopuncture group, LF norm, HF norm and LF/HF showed a significant change after mental stress. But there were no significant difference between two groups(p>0.05). In pharmacopuncture group, LF norm, HF norm and LF/HF showed a significant change after pharmacopuncture injection. There were significant difference between two groups(p<0.01). Conclusions : The result suggests that Hwangryunhaedok-tang pharmacopuncture at $CV_{17}$(Jeonjung) can regulate and prevent the alteration of autonomic nerve system due to mental stress.

• Journal of Sasang Constitutional Medicine
• /
• 제25권4호
• /
• pp.384-395
• /
• 2013

Objectives We report a series of 3 chronic tension-type headache cases who were constitutionally typed as the Soeum type, Taeeum type and treated with Dangguibaekhaoguanjung-tang, Chungshimyeonja-tang or Chunghyulganggui-tang. Methods In treating 1 patient who was constitutionally typed as the Soeum type, Case 1 fell into the category of the Taeeum symptomatology, 2 patients who were constitutionally typed as the Taeeum type, Case 2 and Case 3 fell into the category of Dry-Heat symptomatology. Each patient was given Sasang medication according to protocol: Dangguibaekhaoguanjung-tang to Case 1, Chungshimyeonja-tang to Case 2, Chunghyulganggui-tang to Case 3. On admission day and approximately 2 weeks later, patients evaluated their pain and quality of life using SF-36 and HIT-6. The patients symptoms were observed daily and NRS scores were recorded daily. Results and Conclusions 2 Patients(Case1, Case2) showed improvement in their NRS scores, SF-36 scores and HIT-6 scores. 1 patient(Case3) showed improvement in NRS scores, but worse SF-36 scores and no improvement in HIT-6 scores. Treating chronic tension-type headache based on Sasang Constitutional therapy was found to be effective for managing pain. The treatment protocol suggested in this investigation should be explored and verified in future studies.

• The Journal of Internal Korean Medicine
• /
• 제45권2호
• /
• pp.140-148
• /
• 2024

Objective: In this case study, we describe the use of Shihogayonggolmoryo-tang-gami to treat an in-patient with delirium. Methods: An in-patient with symptoms of delirium was treated with Korean medicine therapies, including the herbal medication Shihogagyonggolmoryo-tang-gami, for 7 days. To evaluate its therapeutic effect, we used the Nursing Delirium Screening Scale (Nu-DESC) and Memorial Delirium Assessment Scale (MDAS). Results: After the treatment, Nu-DESC and MDAS scores improved. Of note, instances of the patient calling out improved, in addition to the patient's sleeping pattern. Although all the symptoms of delirium did not disappear completely, Shihogayonggolmoryo-tang-gami had therapeutic effects. Conclusion: These results suggest that Shihogayonggolmoryo-tang-gami may have a beneficial effect on delirium, without using other antipsychotic medications.

• Journal of Sasang Constitutional Medicine
• /
• 제23권2호
• /
• pp.263-274
• /
• 2011

1. Objectives: We report a series of 4 obesity cases who responded well to the weight-loss therapy based on the Taeeum Sasang constitutional therapy. 2. Methods: In treating 4 obese patients who were constitutionally typed as the Taeeum type, Case 1 and Case 2 fell into the category of the Lung Dry-Cold symptomatology, Case 3 into the Dry-Heat symptomatology, and Case 4 into the Exterior-Interior Combined symptomatology. Each patient was given Sasang medication according to protocol: Taeeumjowi-tang (Taiyintiaowei-tang) to Case 1 and Case 2, Cheongpyesagan-tang (Qingfeixiegan-tang) to Case 3, and Seunggijowi-tang (Chengqitiaowei-tang) to Case 4. On each visit to the clinic (7-21 times in total), the patients were checked on their general condition and change in body weight. 3. Results and Conclusions: All patients showed improvements in their general condition and a satisfactory decrease in weight (Case 1 showed a decrease of 12.7 kg in 84 days, Case 2 a decrease of 8.9 kg in 39 days, Case 3 a decrease of 33 kg in 250 days, and Case 4 a decrease of 29.3 kg in 155 days). Treating obesity based on Taeeum constitutional therapy was found to be effective for weight loss and general improvement of health. The sustained effects of the therapy should be checked during the following visits. The obesity treatment protocol suggested in this investigation should be explored and verified in future studies.

• The Journal of Internal Korean Medicine
• /
• 제39권3호
• /
• pp.443-449
• /
• 2018

Objective: This case reports the management of a patient with bronchiectasis treated with Sikyungbanha-tang, an herbal extract covered by national health insurance. Methods: Twice a year, the patient was treated for a 30-day period with the herbal extract Sikyungbanha-tang. History-taking and a chest X-ray (CXR) were used to evaluate the effects. Results: Following treatment with herbal medicine, the patient's complaints of symptoms decreased, and improvement was shown on CXR. Conclusions: Sikyungbanha-tang in herbal extract form in insured herbal extracts has effects on the management of bronchiectasis patients.

• The Journal of Internal Korean Medicine
• /
• 제43권2호
• /
• pp.237-243
• /
• 2022

Objective: The purpose of this study is to report the clinical treatment of a nighttime sensation of heat on the palms and soles of the feet of a 71-year-old female patient using Sammulhwanggeum-tang. Methods: Sammulhwanggeum-tang was administered for 19 days to reduce the patient's symptoms, which were assessed using a visual analog scale (VAS) and by duration. Results: The heat sensation began to improve after four days and continued to do so for the subsequent 15 days. From May 12, X to May 30, X, the degree of subjective symptoms decreased from a VAS score of 10 before treatment to 0 after treatment, and their daily duration decreased from 10 to 0 hours. In addition, considering that the duration of the patient's symptoms was about 30 days, the duration of the symptoms decreased to 17 days, including the period before the start of treatment. Conclusion: This clinical study suggests that Sammulhwanggeum-tang might be effective in resolving the sensation of heat on the palms and soles of the feet at night.

• Proceedings of the PSK Conference
• /
• 대한약학회 2000년도 NEW STRATEGY FOR DRUG DEVELOPMENT IN POST-GENOMIC ERA(대한약학회)
• /
• pp.246.1-246.1
• /
• 2000

• The Journal of Internal Korean Medicine
• /
• 제29권1호
• /
• pp.200-218
• /
• 2008

Objectives : The purpose of this study was to investigate the effects of Injinchunggan-tang (Yinchenchinggan-tang) on DMN-induced liver damage by applying proteomics. Materials and Methods : Sprague-Dawley rats were used in this experiment and were divided into the normal group (normal saline), the control group (DMN) and the sample group (DMN+IJCGT). DMN was injected i.p. once a day three times a week for 3 weeks in the control group. Normal saline instead of DMN was administered to the normal group. In the sample group, Injinchunggan-tang (Yinchenchinggan-tang) extract was orally administered once a day for 10 days after DMN was induced. The livers of each group were processed and analyzed by histology, Western blot, $Oxyblot^{TM}$, CBB and 2-dimensional electrophoresis. Results : In the histological findings of the liver, IJCGT reduced collagen deposition and liver damage in DMN-induced hepatic fibrosis. IJCGT increased MMP-13 protein production assessed by western blot. Protein oxidation induced by DMN treatment was decreased by IJCGT. In the 2-dimensional electrophoresis finding, the level of the increased proteins induced by DMN treatment such as GRP 75, 58kDa glucose regulated protein and heat shock 70kDa protein 5 were decreased by IJCGT. IJCGT was considered to have the protective effects on hepatotoxicity induced by DMN. In the 2-dimensional electrophoresis finding, the level of increased oxidized proteins such as heat shock 70 protein, mitochondrial malonyltransferase, calreticulin precursor, actin, NADP-isocitrate dehydrogenase, ankyrin repeat and SOCS box protein 11 were decreased by IJCGT. IJCGT was considered to have protective effect on the protein production induced by DMN treatment. Conclusion : Injinchunggan-tang (Yinchenchinggan-tang) exerts an inhibitory effect against the fibrosis and protein oxidation induced by DMN treatment in the rat liver. IJCGT was considered to have protective effects on the hepatotoxicity and protein production induced by DMN treatment.

• Korean Journal of Pharmacognosy
• /
• 제17권3호
• /
• pp.223-231
• /
• 1986

Experimental studies were conducted to investigate for the effect of Mahaengkamsuk-tang on analgesic, antipyretic, antiinflammatory, secretion of respiratory tract, isolated ileum. Mahaengkamsuk-tang was composed of Ephedrae Herba, Armenicae Semen, Glycyrrhizae Radix, Gypsum Fibrosum. The following results has been obtained; analgesic and antipyretic actions were obtained. Anti-inflammatory effects in the paw edema induced by 1% dextran was significantly shown in rats. Spontaneous motilities of isolated ileum of mice were strongly suppressed, and contractions of isolated ileum of mice induced by acetylcholine chloride, barium chloride and histamine were remarkably inhibited. Expectorant effect was shown in rabbits. Continuous hypotensive action was seen.

• The Journal of Internal Korean Medicine
• /
• 제41권5호
• /
• pp.717-723
• /
• 2020

Objectives: The purpose of this study was to address a case of a Parkinson's disease with anorexia and nausea. Methods: A patient diagnosed with Parkinson's disease with anorexia and nausea was treated with Korean medicine therapies including herbal medication (Hyangsayukgunja-tang), acupuncture, electro-acupuncture, and moxibustion for 7days. To evaluate the therapeutic effect, we used a visual analogue scale(VAS). Results: After the treatment, the VAS score for anorexia and nausea had decreased. Conclusion: These results suggested that Korean medicine therapies with Hyangsayukgunja-tang have a beneficial effect on the gastrointestinal symptoms of Parkinson's disease.