• Title/Summary/Keyword: Omega-6

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Physiological Activity of $\omega3$ Polyunsaturated Fatty Acids in Dark Fleshed Fishes I. The Effects on Protein and Phospholipid Contents, and Cholesterol Levels in Rats ($\omega3$ 고도불포화지방산의 생리활성에 관한 연구 I 단백질, 인지질 및 콜레스테롤 함량에 대한 연구)

  • CHOI Jin-Ho;Byun Dae-Seok
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.22 no.2
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    • pp.102-108
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    • 1989
  • The effects of n 3 polyunsaturated fatty acid (PUFA) on protein and phospholipid con-tents, and cholesterol level were studied in rats fed with diets of different fat composition. Body weights of fish oil groups were decreased to $11.1\%\~14.4\%$ compared with lard group (control), and also $16.4\%\~23.3\%$ compared with corn oil group, respectively. Protein contents of $\omega3$ PUFA and sardine oil groups in liver were increased to $6.78\%\~8.51\%$ compared with control group, but were no significant difference in brain and serum. $\omega3$ PUFA and sardine oil slightly repressed the phospholipid in microsome of liver. Moreover they effectively reduced the serum cholesterol levels compared with control group.

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Correlations between the Fatty Acid Composition of Serum Phospholipids and Blood Pressure

  • Lee, Yang-Cha-Kim;Shim, Yoo-Jin;Chung, Eun-Jung;Kim, Soo-Yeon;Yangsoo Jang;Lee, Jong-Ho
    • Nutritional Sciences
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    • v.5 no.2
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    • pp.68-74
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    • 2002
  • Studies of the relationship between the composition of serum fatty acids and blood pressure are complex and controversial. Fatty acids, important constituents of biological membranes, could potentially affect vasoreactivities including blood pressure. In this study the compositions of fatty acids in serum phospholipids were compared between three types of hypertensive subjects (men, pre-menopausal women, and post-menopausal women) and their respective nrmotensive controls. Serum lipids were extracted and phospholipids were separated by thin layer chromatography. The percentage of palmitic acid (16 : 0) in serum phospholipids was significantly higher and the percentage of stearic acid (18 : 0) was significantly lower in all three hypertensive groups, compared with their corresponding control groups. Only in the group of post-menopausal women, palmitic acid was closely associated wish increases in both systolic (SBP) and diastolic blood pressure (DBP), while stearic acid was associated with decreases in both SBP and DBP. The polyunsaturated fatty acids in serum phospholipids behaved differently from saturated fatty acids. The ratios of products / precursor fatty acids, such as $\sumLCPUFA\omega6/18 : 2\omega$6, 20 : 4$\omega$6/18 : 2$\omega$6, ∑LCPUFA$\omega$3/18 : 3$\omega$3 and 22 : 6$\omega$3/20 : 5$\omega$3, were all clearly associated with both SBP and DBP in hypertensive, post-menopausal women. Desaturation and elongation in fatty acid metabolism could affect the bioavailability of eicosanoid precursors. Changes in the constituent fatty acids of phospholipids and eicosanoid precursors may also influence fluidity, ionic transport, hormone receptors and enzyme activities in biological membranes. In conclusion, both systolic and diastolic blood pressure in post-menopausal women was positively associated with the level of palmitic acid, and negatively associated with the level of stearic acid, in serum phospholipids. The relationships between serum phospholipid-$\omega$6 and $\omega$3 series fatty acids and blood pressure in women, especially in post-menopausal women, require further investigation by taking into consideration hormonal status and eicosanoid metabolism. Funker study is needed to determine the value of dietary manipulation of fatty acid constituents of serum phospholipids, relating to hypertension in women.

Unequal Power Divider based on Adjustment Electrical Length of Uniform Transmission Line (단일 전송선로의 전기적 길이 조정을 이용한 비대칭 분배기)

  • Kwon, Sang-Keun;Kim, Young
    • Journal of Advanced Navigation Technology
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    • v.22 no.6
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    • pp.642-647
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    • 2018
  • In this paper, an unequal power divider based on adjusting electrical length of uniform transmission line is presented. This divider consists of three uniform transmission lines and one isolation resistor and have the different port impedances of input and output. The feature of proposed divider can changed the power dividing ratio to adjust only electrical length of uniform transmission lines. To verify the feasibility of proposed power divider, two divider circuits are designed, one is 1:2 power dividing ratio divider with $60{\Omega}$ uniform transmission line and $40{\Omega}$ input port impedances and $45{\Omega}$ output port impedances, the performance data were measured the insertion losses of 1.7 dB/ 5.0 dB, return losses of more than -30 dB and isolation of more than -35 dB. The other is 1:4 power dividing ratio divider with $40{\Omega}$ uniform transmission line and $50{\Omega}$ input port impedances and $75{\Omega}$ output port impedances, the performance data were measured the insertion losses of 1.3 dB/ 6.8 dB, return losses of more than -12 dB and isolation of more than -19 dB. The measured performance data agreed well with the simulated results.

Analysis and Approximation of Linear feedback control problems for the Boussinesq equations

  • 최영미;이형천
    • Proceedings of the Korean Society of Computational and Applied Mathematics Conference
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    • 2003.09a
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    • pp.6-6
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    • 2003
  • In this work we consider the mathematical formulation and numerical resolution of the linear feedback control problem for Boussinesq equations. The controlled Boussinesq equations is given by $$\frac{{\partial}u}{{\partial}t}-{\nu}{\Delta}u+(u{\cdot}{\nabla}u+{\nabla}p={\beta}{\theta}g+f+F\;\;in\;(0,\;T){\times}\;{\Omega}$$, $${\nabla}{\cdot}u=0\;\;in\;(0,\;T){\times}{\Omega}$$, $$u|_{{\partial}{\Omega}=0,\;u(0,x)=\;u_0(x)$$ $$\frac{{\partial}{\theta}}{{\partial}t}-k{\Delta}{\theta}+(u{\cdot}){\theta}={\tau}+T,\;\;in(0,\;T){\times}{\Omega}$$ $${\theta}|_{{\partial}{\Omega}=0,\;\;{\theta}(0,X)={\theta}_0(X)$$, where $\Omega$ is a bounded open set in $R^{n}$, n=2 or 3 with a $C^{\infty}$ boundary ${\partial}{\Omega}$. The control is achieved by means of a linear feedback law relating the body forces to the velocity and temperature field, i.e., $$f=-{\gamma}_1(u-U),\;\;{\tau}=-{\gamma}_2({\theta}-{\Theta}}$$ where (U,$\Theta$) are target velocity and temperature. We show that the unsteady solutions to Boussinesq equations are stabilizable by internal controllers with exponential decaying property. In order to compute (approximations to) solution, semi discrete-in-time and full space-time discrete approximations are also studied. We prove that the difference between the solution of the discrete problem and the target solution decay to zero exponentially for sufficiently small time step.

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Dynamic Birefringence and Viscoelasticity of Polystyrene/Poly, (2,6-dimethyl-1-4-phenylen Oxide)Blends (Polystyrene/Poly(2,6-dimethyl-1,4-phenylene Oxide)블렌드의 동적 복굴절과 점탄성)

  • 황의정
    • The Korean Journal of Rheology
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    • v.9 no.3
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    • pp.89-96
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    • 1997
  • PS/PPO 블렌등의 동적 탄성율 E*($\omega$)와 동적 스트레인-광학계수 O*($\omega$)을 유리전이 영역에서 동시에 측정하여, PS/PPO 3종류조성블렌드의 E*($\omega$)와 O*($\omega$)완화거동을 조성 단 일 중합체와 비교고찰하였다. PS/PPO 블렌드의 $\alpha$-분산 점탄성 거동은 조성에 관계없이 거 의 유사하여 조성 고분자가 상호 협동적으로 완화하는 것을 알수 있었다. 그러나 광학적 완 화 스펙트럼 O*($\omega$)는 정성적으로 명확히 다른 거동을 보였다. 단일 PS와 PPO의 O*($\omega$)는 전 영역에 걸쳐 상반된 부로를 나타냈으며 두 고분자의 블렌드는 조성고분자의 반대부호를 상호보상으로 인하여 복굴절이 감소하였다. 3종류블렌드는 PPO의 조성이 증가함에 따라 상 호보상에 의해 O*($\omega$)의부호가 순차적으로 변하여 반전하였으며, 저 복굴절 PS/PPO 블렌드 의 PS조성이 65-80wt% 범위내에 있음을 추정할수 있었다. 상이한 부호를 갖는 복굴절 특 성으로 인하여 블렌드 내에서 각 성분 고분자의 완화 기여를 다순 가성법칙에 의해 정량적 으로 계산하는 것이 가능하였다. 또한 PS/PPO 블렌드의 상용성을 광학적 부분 기여 파라메 터를 사용하여 고찰하였다.

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Studies on Intake and Serum Concentrations of Fatty Acids in Korean Adolescents

  • Chung, Eun-Jung;Kim, Soo-Jung;Um, Young-Sook;Ahn, Hong-Seok;Lee, Dong-Hwan;Lee, Yang-Cha-Kim
    • Nutritional Sciences
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    • v.1 no.1
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    • pp.42-50
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    • 1998
  • In this study, we evaluated the dietary fatty-acid pattern and serum fatty-acid composition of middle school students (total, 355 ; male, 182 ; female, 173), who are vulnerable to excessive and unbalanced food intakes such as fatty acids and energy. In serum lipid levels, total Chol (p<0.05) and HDL-Chol (p<0.001) levels of female students were significantly higher than those of mal, students. The average fat intake was 23-26 energy % which falls in with the current recommendation level (15-25%) for adults. Although the average P/M/S ratio of dietary fat was 1.1/1.2/1.0 which approaches the recommended ratio, the average range of $\omega$6/$\omega$3 fatty acid ratio of dietary fat was found to be 12.0-16.5, which is higher than the presently recommended range of 4 -10. Some of the very high values found in this study were partly explained by the fact that the range of individual variation of $\omega$6/$\omega$3 ratios was very large. Mean daily intake of Chol was 357-361 mg. The n3 fatty acid intake of middle school students was higher in the LFHM (high fish low meat) group than in the LFHM (low fish high meat) group. EPA and DHA intakes appeared to be significantly higher (p<0.01) in the HFLM group than in the LFHM group as expected. Dietary total $\omega$3 fatty acids (p<0.05) and EPA (p<0.01) were also negatively associated with serum AA($\omega$6) levels. Interestingly, energy intakes and dietary SEAs such as 12 : 0 (p<0.05), 14 : 0 (p<0.01) and 16 : 0 (p<0.05) were negatively associated with serum AA ($\omega$6) levels. To lower the $\omega$6/$\omega$3 ratio of dietary fatty acids for children, frequent consumption of $\omega$3 series fatty-acid rich foods such as soy bean, bean products and fish is recommended. Detailed guidelines should be developed in recommending balanced food intake and qualitative fat intake for Korean adolescents taking heterogeneous groups into consideration. In accurately evaluating fatty acid intake, it is also necessary to have the fatty acid composition data of all foods consumed in each country.

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A Study on Point Defect Induced with Neutron Irradiation (중성자 조사에 의해 생성된 점결함 연구)

  • 김진현;이운섭;류근걸;김봉구;이병철;박상준
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.3 no.3
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    • pp.165-169
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    • 2002
  • Silicon wafer is very important accuracy make use semiconductor device substrate. In this research, for the uniformity dopant density distribution obtained to Neutron Transmutation Doping on make use Si in P Doping study work. In this research. we irradiated neutron on FZ silicon wafers which had high resistivity (1000~2000 ${\Omega}$cm), HANARO reactor was utilized resistivity changes due to observed, the generation of neutron irradiation on point defect analyzed, point defect on resistivity changes inquire into the effect. Before neutron irradiation theoretical due to calculated 5 ${\Omega}$-cm, 20.1 ${\Omega}$-cm for HTS hole and 5 ${\Omega}$-cm, 26.5 ${\Omega}$-cm, 32.5 ${\Omega}$-cm for IP3 hole. After neutron irradiation through SRP measurement the designed resistivities were approached, which were 2.1 H-cm for HTS-1, 7.21 ${\Omega}$-cm for HTS-2, 1.79 ${\Omega}$-cm for IP-1, 6.83 ${\Omega}$-cm for IP-2, 9.23 ${\Omega}$-cm for IP-3, respectively. Also after neutron irradiation resistivity changes due to thermal neutron dependent irradiation hole types free.

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Genomics Approach to Identify the Cause of the Missing Omega-5 Gliadin Protein in O-Free Wheat

  • Lee, Yun Gyeong;Choi, Sang Chul;Kang, Yuna;Kang, Chon-Sik;Kim, Changsoo
    • Plant Breeding and Biotechnology
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    • v.6 no.4
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    • pp.413-425
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    • 2018
  • A previous work developed and identified a new omega-5 gliadin deficient wheat line named O-free by crossing Keumkang and Olgeuru, which is nutritionally quite meaningful in that omega-5 gliadin is one of the known wheat allergens. To verify the characteristics of the O-free, we performed RNA sequencing (RNAseq) analysis of the O-free and the two parent lines (Keumkang and Olgeuru). The results of the similarity analysis with the ESTs for gliadins and glutenins showed that the O-free ESTs had no similarity with the omega-5 gliadin sequences but had similarity to other gliadins and glutenins. Furthermore, mapping results between the raw RNAseq data from the O-free and the omega-5 gliadin sequence showed a clear deletion of the N-terminal sequences which are an important signature of omega-5 gliadin. We also designed specific PCR primers that could identify omega-5 gliadin in the genomic DNA. The results showed that no omega-5 gliadin fragments were detected in the O-free. According to these results, we confirmed that the deficiency of omega-5 gliadin in the O-free is not caused by post-transcriptional or post-translational regulations such as epigenetic phenomena but by a simple deletion in the chromosome. Furthermore, we showed that the low-molecular weight glutenin subunit (LMW-GS) gene in the O-free had a single nucleotide polymorphism (SNP) causing a premature stop codon, resulting in a truncated polypeptide. We expect that the O-free line may serve as an excellent source of wheat that could prevail in the hypo-allergen wheat market, which has recently gained interest world-wide.

Review on the Efficacy of Omega-3 in the Treatment of Attention-Deficit Hyperactivity Disorder (주의력결핍 과잉행동장애에서 오메가-3의 효과에 대한 고찰)

  • Park, So-Young;Lee, Soyoung Irene;Lee, Moon-Soo
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.27 no.1
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    • pp.31-38
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    • 2016
  • Pharmacotherapy is considered the first line therapy in attention-deficit hyperactivity disorder (ADHD). Many patients also choose complementary medicine such as dietary supplements. Omega-3 has shown some efficacy for improving ADHD symptoms in several studies. The goal of this review is to integrate the previous research findings on omega-3 and understand the issues worth considering in the treatment of ADHD. The terms "attention deficit disorder with hyperactivity", "omega-3", and "dietary supplements" were searched on PubMed, Cochrane, and Google scholar. The search was further limited to clinical trials, reviews, and meta-analyses. Trials that examined treatments for ADHD, used randomized design, and placebo-controlled trials were included. Eighteen clinical trials with a total of 1,141 participants were included in this review. Fifteen trials had parallel designs, comparing an omega-3/6 polyunsaturated fatty acid (PUFAs) or a combination of both to a placebo and three compared omega-3/6 PUFAs to a placebo and psycho-stimulants. Seven of the included trials showed significant improvements in groups receiving omega-3/6 PUFAs compared to placebo groups, however, 11 trials showed no significant differences. Evidence that PUFAs supplementation provides benefits for ADHD was yet limited. Mixed results were due to selection variability criteria, variability of supplementation, and short follow-up intervals.

Lipid and Fatty Acid Composition of Korean Breast Milk and Infant Formula (모유와 유아용 조제분유의 지질 및 지방산 조성)

  • 임현숙
    • Journal of Nutrition and Health
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    • v.27 no.6
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    • pp.563-573
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    • 1994
  • This study was conducted to compare the lipid content and fatty acid composition of the Korean breast milk produced at 1, 2 and 3 months postpartum with the infant formula produced in Korea. The content of total lipids of the breast milk was low compared with the other data of Korean as well as foreign breast milk, and the content tended to reduce during the progress of lactation. The composition of fatty acids of the breast milk was characterized by low saturated fatty acids(SFA) and high $\omega$3 series of polyunsaturated fatty acids (PUFA), especially 20:5 and 22:6, so the P/S and $\omega$6/$\omega$3 rations were high. The formulas had more total lipids, triglycerides(TG) and phospholipids and less cholesterol(CHOL) and free fatty acids than the breast milk. The cholesterol content of the formulas was around 50% of that of the breast milk, so the CHOL/TG ratio was low. Although the formulas varied in fatty acid composition, the formulas had more SFA and $\omega$6 series of PUFA, but less monounsaturated fatty acids and $\omega$3 series of PUFA than the breast milk. This study shows that there are some differences in lipid content and fatty acid composition between breast milk and infant formula. Therefore, further studies needed to investigate the physiological effect of this difference on lipid metabolism of infants.

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