• Title/Summary/Keyword: Objective signs

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A descriptive study of on-farm biosecurity and management practices during the incursion of porcine epidemic diarrhea into Canadian swine herds, 2014

  • Perri, Amanda M.;Poljak, Zvonimir;Dewey, Cate;Harding, John CS.;O'Sullivan, Terri L.
    • Journal of Veterinary Science
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    • v.21 no.2
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    • pp.25.1-25.16
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    • 2020
  • Porcine epidemic diarrhea virus (PEDV) emerged into Canada in January 2014, primarily affecting sow herds. Subsequent epidemiological analyses suggested contaminated feed was the most likely transmission pathway. The primary objective of this study was to describe general biosecurity and management practices implemented in PEDV-positive sow herds and matched control herds at the time the virus emerged. The secondary objective was to determine if any of these general biosecurity and farm management practices were important in explaining PEDV infection status from January 22, 2014 to March 1, 2014. A case herd was defined as a swine herd with clinical signs and a positive test result for PEDV. A questionnaire was used to a gather 30-day history of herd management practices, animal movements on/off site, feed management practices, semen deliveries and biosecurity practices for case (n = 8) and control (n = 12) herds, primarily located in Ontario. Data was analyzed using descriptive statistics and random forests (RFs). Case herds were larger in size than control herds. Case herds had more animal movements and non-staff movements onto the site. Also, case herds had higher quantities of pigs delivered, feed deliveries and semen deliveries on-site. The biosecurity practices of case herds were considered more rigorous based on herd management, feed deliveries, transportation and truck driver practices than control herds. The RF model found that the most important variables for predicting herd status were related to herd size and feed management variables. Nonetheless, predictive accuracy of the final RF model was 72%.

Genetic factors influencing milk and fat yields in tropically adapted dairy cattle: insights from quantitative trait loci analysis and gene associations

  • Thawee Laodim;Skorn Koonawootrittriron;Mauricio A. Elzo;Thanathip Suwanasopee;Danai Jattawa;Mattaneeya Sarakul
    • Animal Bioscience
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    • v.37 no.4
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    • pp.576-590
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    • 2024
  • Objective: The objective of this study was to identify genes associated with 305-day milk yield (MY) and fat yield (FY) that also influence the adaptability of the Thai multibreed dairy cattle population to tropical conditions. Methods: A total of 75,776 imputed and actual single nucleotide polymorphisms (SNPs) from 2,661 animals were used to identify genomic regions associated with MY and FY using the single-step genomic best linear unbiased predictions. Fixed effects included herd-year-season, breed regression, heterosis regression and calving age regression effects. Random effects were animal additive genetic and residual. Individual SNPs with a p-value smaller than 0.05 were selected for gene mapping, function analysis, and quantitative trait loci (QTL) annotation analysis. Results: A substantial number of QTLs associated with MY (9,334) and FY (8,977) were identified by integrating SNP genotypes and QTL annotations. Notably, we discovered 17 annotated QTLs within the health and exterior QTL classes, corresponding to nine unique genes. Among these genes, Rho GTPase activating protein 15 (ARHGAP15) and catenin alpha 2 (CTNNA2) have previously been linked to physiological traits associated with tropical adaptation in various cattle breeds. Interestingly, these two genes also showed signs of positive selection, indicating their potential role in conferring tolerance to trypanosomiasis, a prevalent tropical disease. Conclusion: Our findings provide valuable insights into the genetic basis of MY and FY in the Thai multibreed dairy cattle population, shedding light on the underlying mechanisms of tropical adaptation. The identified genes represent promising targets for future breeding strategies aimed at improving milk and fat production while ensuring resilience to tropical challenges. This study significantly contributes to our understanding of the genetic factors influencing milk production and adaptability in dairy cattle, facilitating the development of sustainable genetic selection strategies and breeding programs in tropical environments.

Treatment outcome and long-term stability of orthognathic surgery for facial asymmetry: A systematic review and meta-analysis

  • Yoon-Ji Kim;Moon-Young Kim;Nayansi Jha;Min-Ho Jung;Yong-Dae Kwon;Ho Gyun Shin;Min Jung Ko;Sang Ho Jun
    • The korean journal of orthodontics
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    • v.54 no.2
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    • pp.89-107
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    • 2024
  • Objective: This systematic review aimed to provide a comparative analysis of the treatment outcomes, including hard and soft tissues, postoperative stability, temporomandibular disorders (TMD), and quality of life (QoL), in patients with facial asymmetry who underwent orthognathic surgery. Methods: The primary objective was to address the question, "How do different factors related to surgery affect the outcomes and stability of orthognathic surgery in the correction of facial asymmetry?" A meta-analysis was conducted on the outcome parameters, such as skeletal, dental, and soft tissue symmetry, TMD, QoL, and relapse, using the Hartung-Knapp-Sidik-Jonkman method for random-effects models. Subgroup analyses were conducted considering surgery-related factors such as surgical techniques (one-jaw vs. two-jaw), use of the surgery-first approach, utilization of computer simulation, and analytical methods employed to evaluate asymmetry (2D vs. 3D). Results: Forty-nine articles met the inclusion criteria. The metaanalysis demonstrated a significant improvement in the symmetry of hard and soft tissues. The subgroup analysis indicated that the treatment outcomes showed significant improvement, regardless of the factors related to surgery. Changes in TMD signs and symptoms varied according to the surgical technique used. Quality of life improved in the facial, oral, and social domains. Skeletal relapse was observed during the follow-up. Conclusions: Our findings support the positive outcomes of orthognathic surgery in the treatment of facial asymmetry in terms of skeletal and soft tissue improvements, stability, relief of TMD symptoms, and enhancement of QoL. However, most of the included studies showed a low certainty of evidence and high heterogeneity.

Development of wind vortex shedding coefficients for a multisided cylinder structure

  • Chang, Byungik;Neill, Michael;Issa, Roy;Miller, Aaron
    • Wind and Structures
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    • v.18 no.2
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    • pp.181-194
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    • 2014
  • A major problem with high-mast light poles is the effects that wind vortex shedding can have on the pole itself because of the lock-in phenomenon. It is desired that the coefficients in the AASHTO Standard Specifications ($5^{th}$ edition) for Structural Supports for Highway Signs, Luminaries, and Traffic Signals be analyzed and refined. This is for the belief that the span of the shapes of poles for which the coefficients are used is much too broad and a specific coefficient for each different shape is desired. The primary objective of this study is to develop wind vortex shedding coefficient for a multisided shape. To do that, an octagonal shape was used as the main focus since octagonal cross sectioned high-mast light poles are one of the most common shapes in service. For the needed data, many wind parameters, such as the static drag coefficient, the slope of aerodynamic lift coefficient, Strouhal number, the lock-in range of wind velocities producing vibrations, and variation of amplitude of vortex-induced vibration with Scruton number are needed. From wind tunnel experiments, aerodynamic parameters were obtained for an octagonal shape structure. Even though aerodynamic coefficients are known from past test results, they need to be refined by conducting further wind tunnel tests.

Evaluation of Effects of a Clinical Reasoning Course among Undergraduate Nursing Students (시뮬레이션을 적용한 임상추론 교과목의 적용효과: 일 대학의 예를 중심으로)

  • Lee, Ju-Hee;Choi, Mo-Na
    • Korean Journal of Adult Nursing
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    • v.23 no.1
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    • pp.1-9
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    • 2011
  • Purpose: To evaluate undergraduate nursing students' ability in clinical competence, critical thinking, and problem solving following enrollment in a clinical reasoning course. Methods: A clinical reasoning course utilizing a human patient simulator and scenarios was offered to 22 senior students at a College of Nursing in Seoul. Students' clinical competence was measured with a checklist of 15 items by analyzing students' performance recorded on video tapes for eight scenarios. Critical thinking disposition and problem solving were measured by a self-administered questionnaire before and after the course. Data were analyzed using descriptive statistics and Wilcoxon signed-rank test. Results: The high scored items of clinical competence were: 'obtain relevant subjective/objective data', 'interpret vital signs', 'communicate with healthcare providers', and 'utilize standard precautions including handwashing.' Students' critical thinking and problem solving scores following the course were increased with statistical significance. Conclusion: A clinical reasoning course utilizing a human patient simulator creates a realistic clinical environment for nursing students and provides the opportunity to obtain clinical competence, critical thinking, and problem solving skills.

Making Utility-Integrated Energy Storage a Used, Useful and Universal Resource

  • Doosan GridTech
    • KEPCO Journal on Electric Power and Energy
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    • v.4 no.1
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    • pp.1-7
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    • 2018
  • Objective signs are everywhere that the stationary energy storage market is growing up quickly. The use of distributed resources such as solar photovoltaics and electric vehicles are expanding at a rapid pace, creating technical challenges for the distribution system that will require energy storage and a new generation of software to address. This paper is intended for distribution utility managers and executives and makes the following points: ${\bullet}$ Utility-integrated (as opposed to merely grid-connected) energy storage projects represent a distinct, new wave of industry growth that is just getting underway and is required to manage distributed energy resources moving forward. ${\bullet}$ Utilities and the energy storage industry have important roles to lower risk in adopting this technology - thereby enabling this wave of growth. ${\circ}$ The industry must focus on engineering energy storage for adoption at scale - including the creation and support of software open standards -both to drive down costs and to limit technology and supplier risk for utilities. ${\circ}$ Utilities need to take a program-based, rather than a project- based, approach to this resource to best balance cost and risk as they procure and implement energy storage. By working together to drive down costs and manage risk, utilities and their suppliers can lay the energy storage foundation for a new, more digital distributed electricity system.

A Clinical Study on Patients of Scoliosis (척추측만증 환자에 관한 임상적 고찰)

  • Park, Min-Jung;Seo, Jin-Woo;Park, Kwae-Hwan;Lee, Kyung-Yun
    • The Journal of Korea CHUNA Manual Medicine
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    • v.5 no.1
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    • pp.205-211
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    • 2004
  • Objective : This study is designed to provide clinical data about patients of scoliosis for clinicians. Methods : We investigated 112 patients who have signs and symptoms of scoliosis. visited Vertebral -Joint Center of Conmaul Oriental Medical Hospital from January 2003 to July 2004. We measured Cobb's angle in the 112 patients' X-ray of full spine AP and lateral view and also analyzed age, sex, chief complaints. Results : 1. We investigated 72 female and 40 male patients. The most common distribution of age was 20's in both sex. 2. In the scoliosis angle : The average scoliosis angle was $9.27^{\circ}{\pm}6.06^{\circ}$ in 112 patients. The average scoliosis angle of 40 male patients was$8.9^{\circ}{\pm}6.77^{\circ}$. The average scoliosis angle of 72 female patients was $9.48^{\circ}{\pm}5.67^{\circ}$. 3. The most common region of scoliosis was thoracic spine with 37 patients. 4. The most common chief complaint was low back pain with 69 patients. In the 48 patients. self awareness of scoliosis was included in the chief complaint.

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Acute Toxicity Study on Ssanghwa-tang Fermented with Nuruk in ICR Mice (ICR 마우스를 이용한 누룩 고체 발효 쌍화탕의 급성독성에 관한 연구)

  • Lee, Ji-Hye;Um, Young-Ran;Ma, Jin-Yeul
    • Korean Journal of Oriental Medicine
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    • v.16 no.3
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    • pp.149-154
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    • 2010
  • Objective : Ssanghwa-tang has been used as herbal medine, favorite beverage or health beverage. This study was performed to evaluate the acute toxity and safety of fermented Ssanghwa-tang extract in ICR mice. Methods : 0(control group), 1250, 2500 and 5000 mg/kg of Ssanghwa-tang and fermented Ssanghwa-tang extracts were orally administered to 35 male and 35 female ICR mice. After single administration, we observed number of death, clinical signs, changes of body weight for 14 days. After 14 day of administration, all mice were sacrificed and major organ were observed. Results : Compared with the control group, we could not find any toxic alteration in all treated groups (1250, 2500 and 5000 mg/kg). Conclusions : These results suggest that Sssanghwa-tang fermented with nuruk extracts might be safe to ICR mice.

Study on the Development of a Questionnaire Software for Health Examination in Oriental Medicine (한방건강검진 소프트웨어 개발에 관한 연구)

  • Moon, Jin-Seok;Park, Kyung-Mo;Choi, Sun-Mi
    • Korean Journal of Oriental Medicine
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    • v.13 no.2 s.20
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    • pp.135-142
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    • 2007
  • General health exanimation comes into operation to focus on physical inspection for industrial workers and doesn't contain oriental health care. Thus we need information of health status and disease prevention, so develop a questionnaire software for health examination in oriental medicine. Items of this soft ware consists of personal information and symptoms to could check oneself , pulse and tongue diagnosis by oriental medical doctor. Symptoms are made up of syndrome differentiation about Qi and blood, Yin and Yang, body fluid, five Zang organs, Sasang Constitutional Medicine. And we reconstruct 116 items by whole body, chest and abdomen, urine and feces, head, limbs, waist and back, five sensory organs, objective signs. A subject enter symptoms and a oriental medical doctor input diagnosis of pulse and tongue, then this software return the result of health index and explanation for oriental health care. This software would be used as tool not only health examination but also clinical research.

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A Case Report of Chemotherapy-induced Neuropathic Pain Treated with Oriental Medicine

  • Cho, Jung-Hyo;Kim, Jin-Mi;Kim, Jin-Hee;Oh, Young-Seon;Kim, Cheol-Jung
    • The Journal of Korean Medicine
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    • v.31 no.6
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    • pp.58-63
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    • 2010
  • Objective: We present a case of chemotherapy-induced neuropathic pain with the aim of driving further study evaluating the effectiveness of Oriental medical treatment on patients with neuropathic pain. Method: We prescribed Bogijetong-tang (BJT) two times a day and performed acupuncture and moxibustion once a day over one month of hospitalization. Laboratory tests were performed twice a month during this period. To evaluate the therapeutic effect, Total Symptom Score (TSS) or Visual Analog Score (VAS) was examined at intervals of 7 days. Result: Laboratory data showed no abnormal signs compared with those of initial examination. The patient's subjective symptoms were rapidly relieved within one month. Also, the sums of TSS scores (upper limbs/lower limbs) decreased from 13.64/7.32 to 3.32/3.32 points, and VAS scores (upper limbs/lower limbs) improved from 19/10 to 6/8 points. Conclusion: This case presents a possibility that Oriental medical treatment may offer potential benefits (from an approach aimed at relieving of pain) for patients with chemotherapy-induced neuropathic pain.