• 한방비만학회지
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• 제22권2호
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• pp.136-146
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• 2022

Objectives: The objective of this study is to evaluate weight change and analyze adverse events in overweight and obese women with polycystic ovary syndrome (PCOS) who were prescribed with Gamitaeeumjowee-tang. Methods: A retrospective chart review was conducted for medical records of patients with PCOS, who were administered with Gamitaeeumjowee-tang for a period of 12 weeks between January 2019 and December 2021. Outcomes were total weight loss/weight loss rate, the percentage of patients who lost more than 5% and 10% of their baseline weight. Adverse events (AEs) reported by patients were evaluated by severity, causality and system-organ classes. Results: A total of sixty-seven patients were included (mean±standard deviation, Age 28.78±5.25 years, weight 76.78±12.84 kg, body mass index 29.2±4.26 kg/m²). The average total weight loss in PCOS patients was 6.57±3.07 kg and the average weight loss rate was 8.55±3.65%. The percentage of patients with more than 5% and 10% weight loss compared to their baseline weight was 86.56% and 25.37% respectively. The analysis of adverse events are as follows: Causality assessment with World Health Organization-Uppsala Monitoring Centre of AEs showed 'Unlikely' was the most common (71.7%) and severity evaluations with Common Terminology Criteria for Adverse Events showed almost all symptoms were mild (98.9%). Conclusions: Gamitaeeumjowee-tang helps to lose weight of PCOS patients, which is overweight or obese, and no serious adverse events have occurred. Additional well-designed clinical studies are recommended.

• 한방비만학회지
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• 제5권1호
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• pp.147-155
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• 2005

저자는 한약 복용, 침을 이용한 저주파 전기자극 치료, 이침요법, 부항요법, 행동수정요법, 식이 및 운동지도 등을 중심으로 한 기존의 비만 치료 방법으로 체중 및 체지방 감소를 시도했으나 실패한 경험이 있는 환자를 대상으로 새로운 치료 기술인 약주요법을 위주로 한 프로그램을 적용하여 체중, 체지방률, 복부비만도 등의 지표에서 좋은 경과를 보였으며 기존의 치료에 비해 치료 만족도가 높았던 증례를 경험하였기에 보고하는 바이다.

• 한방재활의학과학회지
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• 제21권2호
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• pp.279-288
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• 2011

Objectives : Our purpose of this study was to evaluate the association between abdominal adipose tissue and oriental obesity pattern identification. Methods : This study was performed in 78 healthy obese(BMI(body mass index)${\geq}25kg/m^2$) women in Seoul. Subjects underwent abdominal CT(computed tomography) scanning and were asked to complete the oriental obesity pattern identification questionnaire. Subjects were given written consent and this study was performed under permission of institutional review board of Kyung-hee East-west Neo medical center. Results : 1. VFA(visceral fat area) and VSR(visceral/subcutaneous adipose tissue ratio) were significantly correlated with stagnation of the liver qi(肝鬱, gan-yu)(p<0.05). But, other patterns were not significantly correlated with oriental obesity pattern identification(p>0.05). 2. We evaluated a difference of oriental obesity pattern identification score in visceral obesity group(n=34) versus non-visceral obesity group(n=44). Scores of all patterns except food accumulation(食積, shi-ji) were significantly higher in the visceral obesity group than in the non-visceral obesity group(p<0.05). Especially, there was a further significant difference in stagnation of the liver qi(肝鬱, gan-yu)(p<0.01). Conclusions : Generally, the stagnation of the liver qi(肝鬱, gan-yu) has a close relation with stress and depression. This study suggests that stress and depression might be correlated with visceral fat, and the use of oriental obesity pattern identification would be helpful for planning a treatment schedule of visceral obesity in the clinic.

• 한국식품영양과학회지
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• 제31권6호
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• pp.1011-1017
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• 2002

본 연구는 소아 비만아들에 대한 임상영양교육 프로그램의 효과를 비만도, 혈액학적 변화, 생활습관의 변화 등을 통해 관찰하였다. 관찰기간이 서로 다른77명의 비만아를 대상으로4년간의 관찰 내용이 분석되었다. 특히 교육효과를 장기와 단기로 나누어 병원 내원 기간중의 단기적 체중, 혈청학적 변화뿐만 아니라 장기적인 식생활 습관의 변화 등으로 나누어 장단기 변화를 구분하여 관찰하였고 이들 장단기 변화에 영 향을 미치는 요인을 규명하고자 하였다. 연구결과 단기적(내원기간동안) 효과면에서 볼 때 BMI, % RBW에 의한 비만도 및 혈액지 질양상 등에서 수치가 낮아짐으로써 통계적으로 유의한 효과가 있었다. 이 중 혈청콜레스테롤의 농도는 평균 180.6 mg/dL에서 165.3 mg/dL으로 감소하여 통계적으로 유의한 차이를 보였고(P<0.05), 28.6%가 정상군으로 돌아왔다 장기 효과를 볼 때, BMI가 23.8$\pm$2.9로 최초 내원시 25.4$\pm$2.7보다 낮아졌으나 통계적으로 유의하지 않았으며, % RBW에 의한 비만도는 137.7$\pm$14.1에서 125.1$\pm$13.0으로 통계적으로 유의하게 감소하였다(p<0.05). 그러나 생활습관을 통해 관찰한 장기 효과는 1차 조사시 57.9점에서 2차 조사시 67.2점으로 통계적으로 유의하게 증가하여 (p<0.01), 임상영양교육후 생활습관이 장기적으로 개선되었음을 알 수 있었다 이는 교육의 효과라 할 수 있고 또한 고도 비만아의 경우 비만율이 현저히 떨어 져,42.9%가 정상군으로 돌아왔다. 단기 효과에 영향을 주는 요인으로는 단기내에 방문기간이 길수록, 방문횟수가 많을수록 교육 후 비만도가 감소하는 경향을 보인(p<0.001) 반면 월평균 교육참여 빈도는 비만치료효과에 긍정적 영향을 주지 않는 것으로 나타났다. 따라서 잦은 참여보다는 지속적이고 장기적인 참여와 관리가 더 효과적이라고 사료된다(p<0.05). 장기 효과와 관련된 관찰로는 방문기간이 길고, 횟수가 많을수록 긍정적 효과를 띠는 경향을 보여주었으나 통계적으로 유의한 수준은 아니었다. 이상의 결과를 요약해보면 임상영양교육프로그램은 적어도 BMI나 %RBW라는 관점에서 장단기 효과가 있었다. 그러나 장기 효과와 단기 효과에 영향을 미치는 요인에는 다소간의 차이가 있었다. 방문기간, 방문횟수 등은 단기 효과에 영향을 주는 요인이나 월평균 참여빈도 등은 별다른 영향을 주지 않는 것으로 나타났다. 반면 장기 효과에 통계적으로 유의한 수준에서 영향을 주는 요인은 규명할 수 없었다. 이는 장기 효과에 영 향을 주는 요인은 단기 효과에서 나타난 총 방문 기간이나 방문횟수 이외의 사회심리적 요인이 복잡하게 작용했을 가능성을 본 연구 결과는 시사하고 있다.

• 한방재활의학과학회지
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• 제24권2호
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• pp.83-93
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• 2014

Objectives The aim of this study is to analyse research trends about oriental obesity pattern identification in Korea. Methods We searched the papers with key words of 'obesity' and 'Pattern identification', 'Syndrom differentiation' in Korean database (Korean traditional knowledge portal, KISS, NDSL, DBPIA, KMBASE, Journal of Korean Medicine Rehabilitation, Journal of Korean Medicine for Obesity Research). We classified the papers by year and content. Results We reviewed 28 searched papers. Papers were published between 1992 and 2012. More than half of the total papers were published since 2008. There are 5 studies that focus on development and improvement of oriental obesity pattern identification questionnaire. 9 studies are research about using oriental obesity pattern identification questionnaire. 7 studies are research about Type of oriental obesity pattern identification. 4 studies are literature review of oriental obesity pattern identification. Other studies related to oriental obesity pattern identification are three. Conclusions To improve application and objectification about oriental obesity pattern identification, more clinical and oriental obesity pattern identification questionnaire studies are needed.

• 한방비만학회지
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• 제21권2호
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• pp.95-104
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• 2021

Objectives: The purpose of this study is to analyze the adverse events and safety of Mahuang used as anti-obesity treatment in Korean medicine. Methods: PubMed, EMBASE, Cochrane, KoreaMed, Oriental Medicine Advanced Searching Integrated System (OASIS) and SCIENCE-ON were used as searching for randomized controlled trials investigating the safety of Mahuang for treating obesity from January, 2000 to July, 2021. Results: Total 6 studies were included for analyzing. In most studies, heart rate was higher in experimental group than in placebo group with statistically significant difference. Both systolic and diastolic blood pressure had no significant differences between both groups, but systolic blood pressure got lower in experimental group. Most adverse events reported in experimental group were dry mouth, constipation, diarrhea, palpitation and insomnia, but serious adverse events were not reported. Conclusions: This study provides the evidence about the safety of Mahuang for treating obesity. However, increase of heart rate and minor adverse events could be occurred. Further study is needed to confirm the safety of Mahuang.

• 대한지역사회영양학회지
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• 제20권4호
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• pp.281-290
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• 2015

Objectives: Obesity is known to influence physical and mental health as well as the general quality of life. The aim of this study was to evaluate the effect of obesity related quality of life on selecting a goal for weight management in overweight and obese female patients. Methods: A total of 140 overweight or obese (Body mass index $23kg/m^2$) female outpatients aged ${\geq}20$ and ${\leq}60$ years from one clinic participated in this study. Patients' desired weight (goal weight, ideal weight, satisfactory weight, acceptable weight and disappointed weight) and obesity related quality of life measures were evaluated. Univariate and multivariate analysis were performed to evaluate the effect of obesity related quality of life on goal weight reduction (%) and goal body mass index (BMI). Results: Mean BMI of overweight group, mild obesity group and severe obesity group were $62.0{\pm}4.8kg$, $68.5{\pm}5.5kg$ and $83.5{\pm}9.6kg$, respectively. Mean weight loss expectations of the three groups were $16.4{\pm}4.7%$, $19.5{\pm}5.3%$ and $30.2{\pm}6.8%$, respectively and goal weight was significantly different among the three groups. Severe obesity group had a lower total quality of life score including physical, work-related, daily living domains than overweight or mild obesity groups. In univariate and multivariate regression analysis, psychosocial domain of quality of life had an effect on goal weight reduction (%) and goal BMI. Conclusions: The results of this study demonstrated that the obese patients with poorer quality of life and psychosocial health tended to choose higher goal weight reduction and lower goal BMI.

• 한방비만학회지
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• 제4권1호
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• pp.161-183
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• 2004

Context : Oriental medicine deals with mind cardinally and effectiveness of CBT on weight control is well-known. but there is no well-structured psychotherapy for weight control like CBT in Oriental medicine so far. Therefore It is necessary to develop new cognitive program based on the theory of Oriental medical. Objective: This study examined whether Yangsung program based on new cognitive weight regulation model is effective on weight loss, self esteem and self control. Design and setting: 44 women were assigned randomly to 2 groups; experimental group(n=24) and control group(n=10). experimental group had 11 sessions consisted of cognitive therapy, meditation, general diet and exercise education. Control group had personal interview with general diet and exercise education and ear acupuncture once a week for two months. All subjects were weighed and evaluated with Rosenberg self esteem scale, and three factor eating questionnaires at the beginning of the program and at the end of the program. Result: Experimental group reported significant changes of weight, self esteem, restraint eating, disinhibition and hunger(p<0.01). Compared with control group, more significant(p<0.05) Weight reduction and self-esteem enhancement were reported in experimental group than control group. There is no significant difference between two groups in changes of restraint eating, disinhibition and hunger.

• 한방비만학회지
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• 제22권1호
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• pp.86-92
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• 2022

26명의 환자에게 8~12주동안 산삼복합약침과 한약을 병행한 식이요법을 시행하여 체성분 변화에 미치는 영향을 알아보았다. 체성분 검사 결과 체중, BMI, 골격근량, 체지방량, 복부지방률, 내장지방단면적, 체지방률이 유의하게 감소하였고, 체중이 감소하면서 골격근량이 감소하긴 하였으나 체지방량 위주의 감소로 골격근의 비율은 오히려 유의하게 증가하였다. 태음조위탕을 증례에 맞게 가감하고, 하루 한 시간 혹은 만 보 걷기의 운동지도를 통해 하루 400~800 kal의 초저열량 식이로 인해 야기될 수 있는 부작용 중 일시적인 현기증과 무기력감 외에 탈모, 부종, 설사, 월경 이상 등은 관찰되지 않았다. 향후 체성분 변화뿐만 아니라 생화학적 검사나 골밀도 검사를 통한 장기적인 탐색이 필요할 것으로 생각한다.

• 대한한의학회지
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• 제43권3호
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• pp.65-78
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• 2022

Objectives: The purpose of this study is to analyze the weight loss and the adverse events of overweight and obese adults on weight loss program with face-to-face treatment (FTF) and non-face-to-face treatment (NFTF) in 6 Korean Medicine obesity clinics. Methods: From March 2nd to March 10th, 2021, we collected data with a retrospective way from overweight and obese adults (body mass index, BMI≥23 kg/m²) who registered for a 12-week Gamitaeeumjowi-tang prescription program. After matching initial information of the FTF group and the NFTF group using propensity matching score, weight loss and BMI change were analyzed, and adverse events were evaluated in terms of causality, severity and system-organ classes. Results: Weight and BMI change from baseline to 12 weeks was -7.98±3.09kg (10.41±3.57%), -3.03±1.14kg/m² and -7.30±3.11kg (9.59±3.45%), -2.76±1.15kg/m² for FTF group and NFTF group, respectively. Body weight and BMI significantly decreased before and after treatment in both groups, and there was no significant difference in weight loss and BMI change between the two groups. No serious adverse events were reported. Conclusions: This study showed the potential that NFTF weight management treatment could be a good alternative way to FTF weight management treatment without serious adverse events.