• 제목/요약/키워드: OMM

검색결과 96건 처리시간 0.027초

초정밀가공기용 오차보상시스템 및 기상측정장치 개발 (Development of Error Compensation System and On the Machine Measurement System for Ultra-Precision Machine)

  • 이대희;나혁민;오창진;김호상;민흥기;김민기;임경진;김태형
    • 한국정밀공학회:학술대회논문집
    • /
    • 한국정밀공학회 2003년도 춘계학술대회 논문집
    • /
    • pp.599-603
    • /
    • 2003
  • This paper present an error compensation system and On-Machine Measurement(OMM) system for improving the machining accuracy of ultra-precision lathe. The Fast-Tool-Servo(FTS) driven by a piezoelectric actuator is applied for error compensation system. The controller is implemented on the 32bit DSP for feedback control of piezoelectric actuator. The control system is designed to compensates three kinds of machining errors such as the straightness error of X-axis slide, the thermal growth error of the spindle. and the squareness between spindle and X-axis slide. OMM is preposed to measure the finished profile of workpiece on the machine-tool using capacitive sensor with highly accurate ruby tip probe guided by air bearing. The data acquisition system is linked to the CNC controller to get the position of each axis in real-time. Through the experiments, it is founded that the thermal growth of spindle and tile squareness error between spindle and X-axis slide influenced to machining error more than straightness error of X-axis slide in small travel length. These errors were simulated as a sinusoidal signal which has very low frequency and the FTS could compensate the signal less than 30 m. The implemented OMM system has been tested by measuring flat surface of 50 mm diameter and shows measurement error less than 400 mm

  • PDF

Proof-of-concept study of the caninized anti-canine programmed death 1 antibody in dogs with advanced non-oral malignant melanoma solid tumors

  • Masaya Igase;Sakuya Inanaga;Shoma Nishibori;Kazuhito Itamoto;Hiroshi Sunahara;Yuki Nemoto;Kenji Tani;Hiro Horikirizono;Munekazu Nakaichi;Kenji Baba;Satoshi Kambayashi;Masaru Okuda;Yusuke Sakai;Masashi Sakurai;Masahiro Kato;Toshihiro Tsukui;Takuya Mizuno
    • Journal of Veterinary Science
    • /
    • 제25권1호
    • /
    • pp.15.1-15.15
    • /
    • 2024
  • Background: The anti-programmed death 1 (PD-1) antibody has led to durable clinical responses in a wide variety of human tumors. We have previously developed the caninized anti-canine PD-1 antibody (ca-4F12-E6) and evaluated its therapeutic properties in dogs with advance-staged oral malignant melanoma (OMM), however, their therapeutic effects on other types of canine tumors remain unclear. Objective: The present clinical study was carried out to evaluate the safety profile and clinical efficacy of ca-4F12-E6 in dogs with advanced solid tumors except for OMM. Methods: Thirty-eight dogs with non-OMM solid tumors were enrolled prospectively and treated with ca-4F12-E6 at 3 mg/kg every 2 weeks of each 10-week treatment cycle. Adverse events (AEs) and treatment efficacy were graded based on the criteria established by the Veterinary Cooperative Oncology Group. Results: One dog was withdrawn, and thirty-seven dogs were evaluated for the safety and efficacy of ca-4F12-E6. Treatment-related AEs of any grade occurred in 13 out of 37 cases (35.1%). Two dogs with sterile nodular panniculitis and one with myasthenia gravis and hypothyroidism were suspected of immune-related AEs. In 30 out of 37 dogs that had target tumor lesions, the overall response and clinical benefit rates were 6.9% and 27.6%, respectively. The median progression-free survival and overall survival time were 70 days and 215 days, respectively. Conclusions: The present study demonstrated that ca-4F12-E6 was well-tolerated in non-OMM dogs, with a small number of cases showing objective responses. This provides evidence supporting large-scale clinical trials of anti-PD-1 antibody therapy in dogs.

A Computer-Aided Inspection Planning System for On-Machine Measurement - Part I : Global Inspection Planning -

  • Lee, Hong-Hee;Cho, Myeong-Woo;Yoon, Gil-Sang;Choi, Jin-Hwa
    • Journal of Mechanical Science and Technology
    • /
    • 제18권8호
    • /
    • pp.1349-1357
    • /
    • 2004
  • Computer-Aided Inspection Planning (CAIP) is the integration bridge between CAD/CAM and Computer Aided Inspection (CAI). A CAIP system for On-Machine Measurement (OMM) is proposed to inspect the complicated mechanical parts efficiently during machining or after machining. The inspection planning consists of Global Inspection Planning (GIP) and Local Inspection Planning (LIP). In the GIP, the system creates the optimal inspection sequence of the features in a part by analyzing the various feature information such as the relationship of the features, Probe Approach Directions (PAD), etc. Feature groups are formed for effective planning, and special feature groups are determined for sequencing. The integrated process and inspection plan is generated based on the sequences of the feature groups and the features in a feature group. A series of heuristic rules are developed to accomplish it. In the LIP of Part II, the system generates inspection parameters. The integrated inspection planning is able to determine optimum manufacturing sequence for inspection and machining processes. Finally, the results are simulated and analyzed to verify the effectiveness of the proposed CAIP.

소형선박 완성목형의 검사기법 및 측정방법 개발에 관한 연구 (The Study on the Survey Technique and a Development of Measuring Method about a Wooden Pattern of the Small Vessel)

  • 정용근;강대선;구현모;이기동
    • 선박안전
    • /
    • 통권23호
    • /
    • pp.65-77
    • /
    • 2007
  • This study is about the survey technique and the development of measuring method about a wooden pattern of the small vessel made by CNC Machine. we will propose a survey method about processing grade, objectivity of survey, an external shape and a surface defect survey method, Furthermore, CMM(Coordinate Measuring Machine) and OMM(On Machine Measurement).

  • PDF

Turning STEP-NC(ISO14649) 정보를 기반한 접촉식 OMM(On-Machine Measurement) Inspection planning에 대한 연구 (A Study on the Tactile Inspection Planning for OMM based on Turning STEP-NC information (ISO14649))

  • 임충일
    • 한국경영과학회:학술대회논문집
    • /
    • 한국경영과학회/대한산업공학회 2003년도 춘계공동학술대회
    • /
    • pp.208-216
    • /
    • 2003
  • ISO 14649 (data model for STEP-NC) is a new interface scheme or language for CAD-CAM-CNC chain under established by ISO TC184 SCI. Up to this point, the new language is mainly made for milling and turning, and other processes such as EDM will be completed in the future. Upon completion, it will be used as the international standard language for e-manufacturing paradigm by replacing the old machine-level language, so called M&G code used since 1950's. With the rich information contents included in the new language, various intelligent functions can be made by the CNC as the CNC knows what-to-make and how-to-make. In particular, On-Machine Inspection required for quality assurance in the machine level, can be done based on the information of feature­based tolerance graph. Previously, On-Machine inspection has been investigated mainly for milling operation, and only a few researches were made for turning operation without addressing the data model. In this thesis, we present a feature-based on-machine inspection process by the 4 Tasks: 1) proposing a new schema for STEP-NC data model, 2) converting the conventional tolerance scheme into that of STEP-NC, 3) modifying the tolerance graph such that the tolerance can be effectively measured by the touch probe on the machine, and 4) generating collision-free tool path for actual measurement. Task 1 is required for the incorporation of the presented method in the ISO 14649, whose current version does not much include the detailed schema for tolerance. Based on the presented schema, the tolerance represented in the conventional drafting can be changed to that of STEP-NC (Task 2). A special emphasis was given to Task 3 to make the represented tolerance accurately measurable by the touch probe on the machine even if the part setup is changed. Finally, Task 4 is converting the result of Task into the motion of touch probe. The developed schema and algorithms were illustrated by several examples including that of ISO 14649 Part 12.

  • PDF

객체메모리모델을 이용한 모바일 전자상품권 설계 (Design of a Mobile Electronic Voucher Using Object Memory Model)

  • 이성호;차병래;김대규;정기봉;지유강
    • 한국항행학회논문지
    • /
    • 제17권5호
    • /
    • pp.552-559
    • /
    • 2013
  • 최근 모바일을 통한 전자상거래가 증가함에 따라, NFC 기반의 전자상품권 결제 연구가 활발하게 진행되고 있다. 하지만, 대부분의 연구가 전자상품권을 이용한 결제방법에만 집중되어 있어서 전자상품권의 유통이력 추적을 위한 연구는 부족하다. 이러한 문제를 해결하기 위해, 본 논문에서는 전자상품권 유통정보를 저장하기 위한 방법을 제안한다. 제안하는 방법은 전자상품권에 객체메모리모델(OMM)을 적용한다. 전자상품권이 발행되고, 다른 사람에게 양도되고, 결제에 사용될 때마다 관련된 정보가 전자상품권의 객체메모리에 저장된다. 그래서, 우리가 제안하는 전자상품권의 객체메모리는 세 가지 형태의 블록을 갖고 있어서, 전자상품권의 발행, 양도, 결제에 대한 각 정보가 저장된다. 우리는 이 정보를 이용하여 전자상품권의 유통이력을 검색하고 분석할 수 있다. 향후에는 제안한 전자상품권을 구현하고, 유통정보를 분석하는 방법을 제안할 계획이다.

반사경 측정을 위한 타워 방식의 Fold Mirror를 이용한 Fizeau 간섭계 시스템 구성 (A Study on the Tower type Fizeau Interferometer System with a Fold Minor for Measuring Large Optical Lens Profile)

  • 이응석;이기암;김옥현
    • 한국정밀공학회지
    • /
    • 제25권8호
    • /
    • pp.21-28
    • /
    • 2008
  • Fizeau interferometer is used for inspecting the lens surface profile accurately. This study is focused on the design and optical measuring techniques for large optical components, such as a reflection mirror for large area lithography or astronomical purpose. A tower type Fizeau interferometer is designed and set up in horizontally with a 45$^{\circ}$ fold mirror which makes easy to align the optical path of heavy interferometer system. To align the optical path, a five-axes stage for the interferometer is required. This study shows a method of the 45$^{\circ}$ fold mirror alignment by using a three-axis stage instead of adjusting the interferometer itself or measuring object. This system will be installed on the large optics polishing machine during the manufacturing process as an on-machine inspection system.

A Computer-Aided Inspection Planning System for On-Machine Measurement - Part II : Local Inspection Planning -

  • Cho, Myeong-Woo;Lee, Hong-Hee;Yoon, Gil-Sang;Choi, Jin-Hwa
    • Journal of Mechanical Science and Technology
    • /
    • 제18권8호
    • /
    • pp.1358-1367
    • /
    • 2004
  • As a part II of theis research, new local inspection planning strategy is proposed in this paper based on the proposed inspection feature extraction method. In the local inspection planning stage, each feature is decomposed into its constituent geometric elements for more effective inspection planning. The local inspection planning for the decomposed features are performed to determine: (1) the suitable number of measuring points, (2) their locations, and (3) the optimum probing paths to minimize measuring errors and times. The fuzzy set theory, the Hammersley's algorithm and the TSP method are applied for the local inspection planning. Also, a new collision checking algorithm is proposed for the probe and/or probe holder based on the Z-map concept. Finally, the results are simulated and analyzed to verify the effectiveness of the proposed methods.