• The Journal of Korean Obstetrics and Gynecology
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• v.28 no.4
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• pp.21-30
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• 2015

Objectives : The purpose of this study was to analyze the characteristics of the pulse energy in women who complained mild hyperemesis gravidarum. Methods : We analyzed the values of pulse energy on 14 patients who suffered mild hyperemesis gravidarum. The patients’ symptoms were assessed by PUQE (Pregnancy-Unique Quantification of Emesis scale). Statistical analysis was performed using SPSS 18.0 for window program, one way ANOVA, pearson correlation coefficient. Results : The results were as follows. 1. There were no statistically significant pulse energy differences. 2. The Chon pulse energy showed negative correlations with each Kwan and Cheok. 3. PUQE score showed positive correlations with right Chon pulse energy and negative correlations with right Kwan pulse energy. Conclusions : The result suggested that PUQE score changes be positive related with spleen pulse energy and negative related with lung pulse energy.

• The Journal of Korean Obstetrics and Gynecology
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• v.15 no.4
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• pp.238-246
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• 2002

Recently we observed and treated a 49-year-old postmenopausal female with enlarged uterine myoma who taking through the hormone replacement therapy(H.R.T). We regard the cause of this case as insufficiency of kidney-yin(腎陰虛), stagnation or the phlegm and pathologic blood(痰瘀阻滯) and H.R.T. ln general cases, myomas grow in size if estrogen and progesterone is present and do not increase in size if estrogen and progesterone levels are low. So if a woman can get to menopause without having symptoms from the myomas, then it is likely that she will never have problems from the growths that require treatment. But Taking postmenopausal estrogen and progestin replacement therapy can cause myomas to grow. So we recommended her to stop the H.R.T. gave herbal-medicine and acupuncture therapy. Thus we could get a good result as follows. The uterine myomas were significantly declined but no change on it's characters. Hot flush and general conditions were also significantly improved And body weight was lessened for about 4.7kg. But vaginal dryness was appeared, So we planed another therapy for that symptom.

• The Journal of Korean Obstetrics and Gynecology
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• v.18 no.4
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• pp.1-9
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• 2005

Purpose : 이 연구는 SKBR3 인간 유방암 세포주에 대한 Euonymus alatus (Thunb.) Sieb 추출물 (CWE) 의 증식억제, 항산화 작용 및 세포사 유발 효과를 검토하기 위해 이루어 졌다. Methods : SKBR3 세포주는 48시간 동안 다양한 농도 ($0-40\;{\mu}g/ml$)의 CWE를 첨가하면서 배양되었고, 세포의 생존 비율은 MTT 배양을 통해서 평가하였다. 또한 CWE의 증식억제 효과는 유방암 세포주의 세포사와 관련되어 있음을 형태학적인 변화와 올리고뉴클레오솜 DNA 분절을 통해 확인하였다. Results : CWE의 50%에서 효과를 나타내게 하는 약물농도인 $ED_{50}$ (effective dose 50%)은 $9.3+2.2{\mu}g/ml$이며, 약물의 농도에 의존하여 세포의 증식을 억제시켰다. 아울러, 다양한 농도와 배양시간에서 CWE가 ROS 생산을 억제하는 것을 밝힐 수 있었다. 따라서 이러한 작용과 항암예방효과는 농도와 노출 시간에 의존하였다. Conclusion : 이러한 관찰을 통해 Euonymus alatus (Thunb.) Sieb의 열수 추출물은 SKBR3 인간 유방암 세포주에 대해 강한 증식억제 효과와 강력한 항산화효과 및 세포사의 유발 효과를 가지는 것으로 인식할 수 있다.

• The Journal of Korean Obstetrics and Gynecology
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• v.18 no.3
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• pp.127-138
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• 2005

Purpose : This study was designed to establish safety and efficacy of using herbal medicine in pregnancy and to investigate patient's treatment satisfaction. Methods : We investigated general pregnancy outcomes of twenty-five gynecological outpatients who visited Dongguk univ. Kangnam Oriental Hospital, from July 1, 2002 through December 31, 2004 and have taken herbal medicine in pregnancy. Additionally we investigated newborn's growth status and patient's treatment satisfaction. Results : The rate of normal delivery of patients used herbal medicine for diseases that possibility of abortion is not high was 100% and there was no malformation in normally delivered 21 cases. Most of Newborn's growth status was normal and the average score of patient's satisfaction was 3.5(absolutely satisfied=5). Conclusion : The results of this study show safety and efficacy of using herbal medicine in pregnancy. And In the future, It is thought that more exactly constructed clinical survey need to be carried out.

• The Journal of Korean Obstetrics and Gynecology
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• v.29 no.4
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• pp.1-12
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• 2016

Objectives: The purpose of this study is to analyze the correlation between the pulse energy and hot flush in women who complain of climacteric syndrome. Methods: We analyzed the values of pulse energy on 78 of perimenopausal and postmenopausal women. The symptoms of patients were assessed by Kupperman’s index (KI) and Menopause Rating Scale (MRS). Statistical analysis was performed by Spearman correlation coefficient and student T-test, using SPSS 18.0 for window program. Results: The results were as follows. 1. There were no statistically significant relation between pulse energy of left Cheok subtracted from left Chon and KI, MRS hot flush score. 2. When divided depending on MRS hot flush score, There were no statistically significant differences on pulse energy. Conclusions: The results suggest that there is no correlation between hot flush score and pulse energy.

• The Journal of Korean Obstetrics and Gynecology
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• v.18 no.1
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• pp.242-252
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• 2005

Purpose : This study carried out to develop the questionnaires that can measure objectively menstrual quantity and determine quantity index. Method : First, we made questionnaires to measure menstrual quantity by six question. Then we investigated 1309 women's questionnaires who has the menses. Conclusion : 1. the questionnaires that can measure objectively menstrual quantity and determine quantity index was high a correlation coefficient therefore those were used Method of Menstrual Quantity(here after MMQ) calculation. Those were added and averaged. 2. We examined correlation of calculated MMQ and women's questionnaires who has the menses therefore we got 0.30~0.47 correlation. 3. MMQ 1~3(hypomenorrhea) was 39 persons 3.19%, MMQ 4~6(normal menorrhea) was 1050 persons 85.85% and MMQ 7~10(hypermenorrhea) was 134 persons 10.96%. MMQ 4 tended to be little and MMQ 6 tended to be much. 4. MMQ confidence was high as 82% comparatively so we thought MMQ was appropriate as the measured method of menstrual quantity.

• The Journal of Korean Obstetrics and Gynecology
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• v.24 no.4
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• pp.20-30
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• 2011

Purpose: Polycystic ovary syndrome(PCOS) is a common condition characterised by menstrual abnormalities. PCOS is now recognised to be a metabolic syndrome which may include hyperinsulinemia, hyperlipidemia, diabetes mellitus and possibly cardiac disease. Cyperi Rhizoma(CR) can soothe the liver to regulate gi and regulate menstruation to relieve pain. For these reasons, this study was designed to investigate the effects of CR on metabolic syndrome in PCO rats. Methods: Female rats injected with a single dose of 2 mg/kg estradiol valerate (EV) develop PCO, CR was given for 5 weeks. After 5 weeks administration of drugs, body weights, food uptake, Fasting Blood Glucose, Oral Glucose Tolerance Test, Total Cholesterol, HDL-Cholesterol, LDL-Cholesterol and Triglyceride were measured once a week. Results: In this experiment, single injection of EV induced hyperlipidemia, but it did not affect serum glucose levels. Oral administration of CR prevent weight loss shown in control group. In addition, treatment with CR can lower total cholesterol, LDL-cholesterol and triglyceride in serum compared to PCO induced control group. Conclusions: These results suggest that CR can regulate hyperlipidemia in PCOS.

• The Journal of Korean Obstetrics and Gynecology
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• v.28 no.1
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• pp.73-84
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• 2015

Purpose: The purpose of this study is to analyze the characteristics of the pulse energy in women who complain of climacteric and menopausal symptoms. Methods: We analyzed the values of pulse energy on 45 climacteric and menopausal women. The patients' symptoms were assessed by Kupperman's index and Menopause Rating Scale (MRS). Statistical analysis was performed using SPSS 18.0 for window program, one way ANOVA, pearson correlation coefficient. Results: The results were as follows. 1. The pulse energy of the Left Chon was significantly largest and Left Cheok was comparatively smallest. 2. There was no statistically significant correlation in the pulse energy of Left Chon minus Left Cheok, Kupperman's index, MRS total sum score. Conclusions: The results suggest that the pulse energy of the Left Chon tends to be increased and Left Cheok decreased in climacteric and menopausal women.

• The Journal of Korean Obstetrics and Gynecology
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• v.21 no.3
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• pp.75-89
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• 2008

Purpose: To evaluate the hot flush relief efficacy of Yiseontang-gami in climacteric women with hot flushes, a vasomotor symptom. Methods: The 20 subjects who signing on the clinical trial written consent by self-will is registered this clinical trial after decided suitable by selection and exception standard, after take a medical experiment and checkup according to clinical trial plan. Registered subject should valuated by settled schedule after take the testing medicine(Yiseontang-gami)during thirty-day. The evaluating indexes of this trial are hot flush VAS, hot flush frequency, hot flush consistence time, sweating VAS, palpitation VAS, sleep disturbance VAS, MRS, MENQOL, PGA. Results: The results were as follows 1. 4 subjects dropped out of the clinical trial and 16 subjects completed it. 2. After Yiseontang-gami treatment, hot flush VAS, hot flush frequent, sweating VAS. Palpitation VAS, sleep disturbance VAS improved significantly. 3. After Yiseontang-gami treatment, hot flush consistence time was not improved significantly. 4. After Yiseontang-gami treatment, blood test value were not different significantly. Conclusion: In this clinical trial we consider that Yiseontang-gami is suitable treatment for the hot flushes and related symptoms.

• The Journal of Korean Obstetrics and Gynecology
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• v.27 no.1
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• pp.193-205
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• 2014

Purpose: This study was aimed to report the effect of oriental treatment on Bell's palsy during pregnancy with Sasang Constitutional method. Methods: 4 patients who had Bell's palsy during pregnancy were treated with Sasang constitutional prescriptions. After treatments we evaluated the effects by House-Brackmann facial nerve grading system. Results: As a result, the clinical symptoms of Bell's palsy during pregnancy were improved. Conclusions: This case studies show that Sasang constitutional method can be effectively used on Bell's palsy during pregnancy. Especially the diagnostic results by using Diagnosis System of Oriental Medicine (DSOM) revealed that some of patients were in a very weak condition. We could apply these results to choose prescription and get good therapeutic effects.