• Title/Summary/Keyword: Nuclear Program

Search Result 1,192, Processing Time 0.024 seconds

Mitochondrial noncoding RNA transport

  • Kim, Kyoung Mi;Noh, Ji Heon;Abdelmohsen, Kotb;Gorospe, Myriam
    • BMB Reports
    • /
    • v.50 no.4
    • /
    • pp.164-174
    • /
    • 2017
  • Mitochondria are cytosolic organelles essential for generating energy and maintaining cell homeostasis. Despite their critical function, the handful of proteins expressed by the mitochondrial genome is insufficient to maintain mitochondrial structure or activity. Accordingly, mitochondrial metabolism is fully dependent on factors encoded by the nuclear DNA, including many proteins synthesized in the cytosol and imported into mitochondria via established mechanisms. However, there is growing evidence that mammalian mitochondria can also import cytosolic noncoding RNA via poorly understood processes. Here, we summarize our knowledge of mitochondrial RNA, discuss recent progress in understanding the molecular mechanisms and functional impact of RNA import into mitochondria, and identify rising challenges and opportunities in this rapidly evolving field.

Development of 3-D J-Integral Calculation Method for Structural Integrity Evaluation (기기 건전성 평가를 위한 3차원 J-적분 계산 전산코드 응용평가 연구)

  • Kim, Young-Jin
    • Proceedings of the KIEE Conference
    • /
    • 1999.11b
    • /
    • pp.450-454
    • /
    • 1999
  • In order to evaluate the integrity of nuclear power plants, J-integral calculation is crucial. For this purpose, finite element method is popularly used to obtain J-integral. However, high cost time consuming preprocess should be performed to design the finite element model of a cracked structure. Also, the J-integral should be verified by alternative method since it may differ depending on the calculation method. The objective of this paper is to develop a three-dimensional elastic-plastic J-integral analysis system which is named as EPAS. The EPAS program consists of an automatic mesh generator for a through-wall crack and a surface crack, a solver based on ABAQUS program, and a J-integral calculation program which provides DI(Domain Integral) and EDI(Equivalent Domain Integral) based J-integral calculation. Using the EPAS program, an optimized finite element model for a cracked structure can be generated and corresponding J-integral can be obtained subsequently.

  • PDF

Development of 3D Visualization Program Connected with Real-time Simulator (실시간 시뮬레이터와 연계된 3차원 가시화 프로그램 개발)

  • Lee Ji-woo;Lee Myeong-soo;Seo In-yong;Hong Jin-huck;Lee Seung-Ho;Suh Jeong-Kwan
    • Proceedings of the Korea Society for Simulation Conference
    • /
    • 2005.05a
    • /
    • pp.89-92
    • /
    • 2005
  • Each 3D visualization program has its own different structure as for the purpose. This paper describes the design and development of an on-line 3D core data visualization program, $RocDis^{TM}$, for the nuclear simulator. It is possible to analyze the inside of the core status including neutron flux, relative power, moderator and fuel temperature in 3D distribution. Some of other essential information, axial flux distribution etc. could also display in 2D graphs. This program would be design, tuning and training for the simulator core model.

  • PDF

Preliminary Study on the Enhancement of Reconstruction Speed for Emission Computed Tomography Using Parallel Processing (병렬 연산을 이용한 방출 단층 영상의 재구성 속도향상 기초연구)

  • Park, Min-Jae;Lee, Jae-Sung;Kim, Soo-Mee;Kang, Ji-Yeon;Lee, Dong-Soo;Park, Kwang-Suk
    • Nuclear Medicine and Molecular Imaging
    • /
    • v.43 no.5
    • /
    • pp.443-450
    • /
    • 2009
  • Purpose: Conventional image reconstruction uses simplified physical models of projection. However, real physics, for example 3D reconstruction, takes too long time to process all the data in clinic and is unable in a common reconstruction machine because of the large memory for complex physical models. We suggest the realistic distributed memory model of fast-reconstruction using parallel processing on personal computers to enable large-scale technologies. Materials and Methods: The preliminary tests for the possibility on virtual manchines and various performance test on commercial super computer, Tachyon were performed. Expectation maximization algorithm with common 2D projection and realistic 3D line of response were tested. Since the process time was getting slower (max 6 times) after a certain iteration, optimization for compiler was performed to maximize the efficiency of parallelization. Results: Parallel processing of a program on multiple computers was available on Linux with MPICH and NFS. We verified that differences between parallel processed image and single processed image at the same iterations were under the significant digits of floating point number, about 6 bit. Double processors showed good efficiency (1.96 times) of parallel computing. Delay phenomenon was solved by vectorization method using SSE. Conclusion: Through the study, realistic parallel computing system in clinic was established to be able to reconstruct by plenty of memory using the realistic physical models which was impossible to simplify.

Evaluation and Forecast of North Korea's Nuclear Policy through Libya Model (리비아 모델을 통한 북한의 핵 정책 평가와 전망)

  • Han, Seung Jo;Shin, Jin
    • Convergence Security Journal
    • /
    • v.18 no.3
    • /
    • pp.113-122
    • /
    • 2018
  • The issue of security on the Korean peninsula is facing the greatest upheaval in 2018 with the inter-Korean summit and the US-North Korea summit. North Korea has pursued the parallel policy developing military and economic at the same time. However, North Korea is changing its route to give up nuclear weapons and focus on the economy through summit talks. Since the change in North Korea is similar to that of Libya in the past, it is necessary to analyze why North Korea is trying to abandon its nuclear program and how the process is flowing compared to the case of Libya. The Libya model was constructed and analyzed in terms of international and domestic perpectives and recognition of the situation by leadership. North Korea's nuclear policy was evaluated based on the Libya model. The nuclear development of Libya and North Korea has caused diplomatic and economic pressures from the international community and ultimately led to instability of the regime. Two countries have tried to abandon nuclear program in order to solve the instability of the regime, also gain the economic reward insead. Libya took economic benefits and secured some of the stability of the regime, but the regime collapsed under the wave of democracy due to the influx of foreign capital and ideas. North Korea will seek diplomatic and economic gains with the example of Libya, but will try to limit as much as possible the culture of democracy and the full opening that can be incidental.

  • PDF

Determination of a Minimum Detectable Activity through a Measurement of Pu Isotopes in Environmental Samples

  • Lee, M. H.;Jung, E. C.;Song, K.S.
    • Bulletin of the Korean Chemical Society
    • /
    • v.29 no.6
    • /
    • pp.1162-1166
    • /
    • 2008
  • In this paper, several parameters affecting the sensitivity and determining the minimum detectable activity (MDA) for the measurement of the Pu isotopes were investigated. Among the parameters affecting the determination of the MDA values for the Pu isotopes in the environmental samples, amounts of the samples appeared to be crucial factors in decreasing the MDA values. The MDA for the Pu isotopes in the environmental samples were calculated by varying the counting time of the samples and background. The results obtained in this study can be used for an environmental radiation monitoring program regarding the level of concern for a radionuclide beyond which some action may need to be taken.

3-D Model-based UAV Path Generation for Visual Inspection of the Dome-type Nuclear Containment Building (UAV를 이용한 돔형 원자력 격납건물 외관조사를 위한 3차원 모델기반 비행 좌표 생성 방법)

  • Kim, Bong-Geun
    • Journal of KIBIM
    • /
    • v.6 no.1
    • /
    • pp.1-8
    • /
    • 2016
  • This paper provides a method for generating flight path of Unmanned Aerial Vehicle (UAV) that is intended to be used in visual inspection of dome-type nuclear containment building. The method basically employs 3-D model to extract accurate location coordinates. Two basic route patterns that provide guide lines in defining moving locations were defined for each side wall and dome section of the containment. The route patterns support sequential capturing of images as well. In addition, several simple equations and an algorithm for calculation of the moving location on the route were developed on the basis of 3-D geometric characteristics of the containment building. A prototype computer program has been implemented to validate the proposed method, and a case study shows the method can visualize covering area in 3-D model as well.

Natural vibration characteristics of a clamped circular plate in contact with fluid

  • Jhung, Myung Jo;Choi, Young Hwan;Kim, Hho Jung;Jeong, Kyeong Hoon
    • Structural Engineering and Mechanics
    • /
    • v.21 no.2
    • /
    • pp.169-184
    • /
    • 2005
  • This study deals with the free vibration of a circular plate in contact with a fluid; submerged in fluid, beneath fluid or on fluid. An analytical method based on the finite Fourier-Bessel series expansion and Rayleigh-Ritz method is suggested. The proposed method is verified by the finite element analysis using commercial program with a good accuracy. The normalized natural frequencies are obtained in order to estimate the relative added mass effect of fluid on each vibration mode of the plate. Also, the location of plate coupled with fluid and the cases of free and bounded fluid surface are studied for the effect on the vibration characteristics.

Data management process for nuclear fuel replace program construction (핵 연료 교체 프로그램 구축을 위한 데이터 관리 프로세스)

  • Kim Young-Jin;Sin Won-Sik;Jung Hee-Chul
    • Proceedings of the Korean Operations and Management Science Society Conference
    • /
    • 2006.05a
    • /
    • pp.1603-1608
    • /
    • 2006
  • Nuclear power plant have focused constituent that is always safety. However, period set to observe element that is economic performance keeping inner place now. Hereupon, in this study, chose fuel replace that is on one main activity doing at nuclear power plant for the target. And chose computerization and data management for fuel replace process to the direction.

  • PDF

Human Factors Design Review of CFMS for Improving the Safety of Nuclear Power Plant (원전의 안전성 제고를 위한 CFMS의 인간공학적 설계 검토)

  • 이용희;정광태
    • Journal of the Korean Society of Safety
    • /
    • v.12 no.4
    • /
    • pp.201-208
    • /
    • 1997
  • In order to improve the safety of nuclear power plant, we performed a human factors review for the CFMS(Critical Function Monitoring system) design of nuclear power plant. Three works were performed in this study. In first work, we developed human factors engineering program plan(HFEPP) and human factors engineering verification and validation plan (HFE-V & V plan) to effectively perform CFMS design and review. In second work, we identified human engineering discrepancies(HEDs) for CFMS design through human factors design review and proposed those resolutions. In the third work, we developed the evaluation and management methodology for identified KEDs. Methodology developed in this study can be used in other complex system as well as in CFMS design review.

  • PDF