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Effect of Hydrocortisone on Thymus Cells (Hydrocortisone 이 흉선세포(胸線細胞)에 미치는 영향(影響))

  • Ha, Tai-You
    • The Journal of the Korean Society for Microbiology
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    • v.9 no.1
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    • pp.41-45
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    • 1974
  • On day 2 after treatment of Lewis rat with 25mg of hydrocortisone, the cell number in the thymus was reduced to less than 10% of the matched control. By day 12 after hydrocortisone treatment the thymic cell population was recovered almost its original value and on day 24 after treatment the number of thymocytes was equivalent to that of normal thymocytes. The density distribution profile of hydrocortisone treated rats as compared with normal rats showed a marked decrease in the denser fraction D while the lighter fractions. (A plus B, and C) showed a considerable proportional increase. The proportion of dead cells in thymus suspension from hydrocortisone treated rats was higher than that from their normal counterparts. On separation, the dead cells accumulated selectively in the pellet and A fraction. The response of the thymocytes from hydrocortisone treated rats to PHA was increased compared to that from normal rats. Among the subpopulations, D fraction, which was relatively unresponsive in normal rats, showed a marked increase in PHA response and C fraction showed some increase in the response.

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An Extended Numerical Calibration Method for an Electrochemical Probe in Thin Wavy Flow with Large Amplitude Waves

  • Park, Ki-Yong;No, Hee-Cheon
    • Proceedings of the Korean Nuclear Society Conference
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    • 1998.05a
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    • pp.553-558
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    • 1998
  • The calibrating method for an electrochemical Probe, neglecting the effect of the normal velocity on the mass transport, can cause large errors when applied to the measurement of wall shear rates in thin wavy flow with large amplitude waves. An extended calibrating method is developed to consider the contributions of the normal velocity. The inclusion of the turbulence-induced normal velocity term is found to have a negligible effect on the mass transfer coefficient. The contribution wave-induced normal velocity can be classified on the dimensionless parameter V. If V above a critical value of V, $V_{crit}$, the effects of the wave-induced normal velocity become larger with an increase in V. IF V its effects negligible for V < $V_{crit}$. The unknown shear rate is numerically determined by solving the 2-D mass transport equation inversely. The president inverse method can predict the unknown shear rate more accurately in thin wavy flow with large amplitude waves than the previous method.

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Study on masticatory pattern of adult having anterior cross bite (전치부 반대교합 성인의 저작양상에 관한 연구)

  • Sohn, Byung-Wha;Yu, Hyung-Seog;Park, Jong-Jin
    • The korean journal of orthodontics
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    • v.27 no.1
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    • pp.35-44
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    • 1997
  • mastication is basically regulated by central pattern regulalor(CPG) of brain system, target organ output from CPG is modulated by oral sensory feedback, anterior cross bite pattern infuluence the feedback mechanism and change muscle activity and jaw movement. The purpose of this study was to investigate differnce anterior cross bite group from normal group, the selected sample groups were 30 normal patient, 30 anterior cross bite patient. EMG and EGN of Biopak system were used for this study The following results were obtained 1 In resting slate of mandible, anterior cross-bite showed the higher muscle activities in all the muscle.(exception:left digastric muscle) than normal group. 2. In clenching state, No significant difference in muscle activities of normal group and anterior cross bite group was noticed 3. In swallowing state Normal group showed the higher muscle activities in left and right masseter muscle, right posterior temporal muscle. 4. In maximum opening and closing velocity, normal group showed the higher value than anterior cross-bite. 5. In the mean value of the maximum opening,the maximum anterior posterior movemenl from centric-occlusion, the lateral deviation from centric occclusion, normal group showed the higher value than anterior cross-bite group.

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Studies on Selective Separation of Highly Motile Bovine Sperm (고활력우정자(高活力牛精子)의 선택적(選擇的) 분리(分離)에 관한 연구(硏究))

  • Kim, Myung-cheol
    • Korean Journal of Veterinary Research
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    • v.24 no.2
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    • pp.245-266
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    • 1984
  • As a fundamental study to increase the reproductive efficiency in cattle, highly motile sperm were separated and collected from raw semen, extended semen and frozen semen by different methods using various concentrations of bovine serum albumin or Tyrode's solution. Various characteristics and light microscopic and electron-microscopic morphology of sperm separated by different methods were compared. The results obtained were as follows; 1. The sperm separated from raw semen using bovine serum albumin showed significantly high value in motility, motile sperm count, percent of normal sperm and progressive motility, as compared with control sperm and revealed the highest sperm recovery rate when separated with 6% bovine serum albumin. 2. The sperm motility, percent of normal sperm and progressive motility of the highly motile sperm frozen after being separated from raw semen with bovine serum albumin, showed significantly high value than those of a control sperm and especially found the highest value when separated with 20% bovine serum albumin. 3. Light-microscopic percent of abnormality was significantly low in the prefrozen and postfrozen highly motile sperm separated with bovine serum albumin, as compared with control sperm. 4. Electron-microscopic finding of the highly motile sperm separated with bovine serum albumin showed low percent of deformity in the dilatation and vesiculation of cell membrane, in dilatation and density loss of acrosome than in those of control sperm. 5. It was impossible to separate the highly motile sperm from frozen semen with bovine serum albumin, but it was possible with Tyrode's solution. 6. Recovery rate of highly motile sperm from raw semen extended semen and frozen semen was the highest when the sperm pellet stood in Tyrde's solution for 80 minutes. 7. The highly motile sperm separated from raw semen, extended semen and frozen semen with Tyrode's solution showed significantly high value in motility, progressive motility and percent of normal sperm, as compared with control sperm. 8. Highly motile sperm, when separated from raw semen, extended semen and frozen semen with Tyrode's solution, showed significantly low percent of microscopic abnormality as compared with control sperm.

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An Evaluative Study on Forehead Morphology of Individuals with Normal Occlusion and Position of Maxillary Incisor in Accordance to Forehead Morphology (정상교합자의 이마형태와 그에 따른 상악 전치의 위치 평가)

  • Lee, Su-Yong;Lee, Jin-Woo;Cha, Kyung-Suk;Jung, Dong-Hwa;Lee, Sang-Min
    • Journal of Dental Rehabilitation and Applied Science
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    • v.29 no.3
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    • pp.236-248
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    • 2013
  • In this study, 37 subjects with normal facial shape and normal occlusion are classified and reference value for such classification was investigated. Difference in position of maxillary incisor was studied according to the cl assification. Moreover, by investigating correlation between factors affecting forehead morphology and positio n of maxillary incisor, following results have been obtained. 1. Morphology of forehead can be classified as angular type, round type, straight type, and concave type. 2. There were no specific reference value for evaluation of forehead morphology but possibilities of evaluating forehead morphology using S value and forehead length (Tri-Gla) still remain. 3. There were no correlation between forehead morphology and position of maxillary incisor. 4. Forehead inclination and Andrew analysis show statistically significant negative correlation. That is, as forehead inclination increases, maxillary incisor is positioned posteriorly and this relationship can be shown as following equation, Andrew analysis = -0.39*Forehead inclination.

Correlation Analysis Between Gait Pattern and Structural Features of Cerebral Cortex in Patients with Idiopathic Normal Pressure Hydrocephalus (특발정상압수두증 환자의 보행 패턴과 대뇌피질의 구조적인 특징의 상관관계 분석)

  • Yun, EunKyeong;Kang, Kyunghun;Yoon, Uicheul
    • Journal of Biomedical Engineering Research
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    • v.42 no.6
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    • pp.295-303
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    • 2021
  • Idiopathic normal-pressure hydrocephalus (INPH) is considered a potentially treatable neurological disorder by shunt surgery and characterized by a triad of symptoms including gait disturbance, cognitive impairment and urinary dysfunction. Although disorders of white matter are generally viewed as the principal pathological features of INPH, analysis of cortical features are important since the destruction of neural tracts could be associated with cortical structural changing. The aim of the study was to determine whether there was any relationship between gait parameter and structural features of cerebral cortex in INPH patients. Gait parameters were measured as follows: step width, toe in/out angle, coefficient of variation (CV) value of stride length, CV value of stride time. After obtaining individual brain MRI of patients with INPH and hemispheric cortical surfaces were automatically extracted from each MR volume, which reconstructed the inner and outer cortical surface. Then, cortical thickness, surface area, and volume were calculated from the cortical surface. As a result, step width was positively correlated with bilateral postcentral gyrus and left precentral gyrus, and toe in/out was positively correlated with left posterior parietal cortex and left insula. Also, the CV value of stride length showed positive correlation in the right superior frontal sulcus, left insula, and the CV value of stride time showed positive correlation in the right superior frontal sulcus. Unique parameter of cerebral cortical changes, as measured using MRI, might underline impairments in distinct gait parameters in patients with INPH.

Value Evaluation on the Experience Space of the Age-friendly Product (고령친화용품 체험공간에 대한 가치 평가)

  • Oh, Chan Ohk;Joo, Soo Hyun;Jin, Jae Moon;Kim, Soo Young
    • Design Convergence Study
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    • v.16 no.3
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    • pp.17-37
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    • 2017
  • The purpose of this study is to evaluate the value of the center of age-friendly goods to confirm the public value of the center. 152 elderly participants, either who have utilized the center themselves or who have experienced the center indirectly through the image have participated in the study. The experience of age-friendly product center was evaluated by the contingent valuation method, which is widely used in the public services. A double-bounded dichotomous choice (DB-DC) log-logistic model and a log-normal model were conducted. As the result of the estimation, the truncated mean of the log-logistic model was 3,401 Korean won, with the mean of 4,937 won. In addition, the truncated mean of the log-normal model was 3,433 won, with the mean of 4,144 won. Elderly who have not experienced the center placed a higher value on the center, compared to the experienced elderly. The results imply the necessity to enlarge the opportunity for future suppliers to experience the center for age-friendly products, in order to improve their objective understandings. In addition, the necessity of expanding exhibition products and applying age-friendly designs is proposed, to offer various attractive experiences to elderly.

Effects of Green Tea Catechin on Mixed Function Oxidase System and Antioxidative Defense System in Rat Lung Exposed to Microwave

  • Kim, Mi-Ji;Rhee, Soon-Jae
    • Preventive Nutrition and Food Science
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    • v.9 no.1
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    • pp.53-57
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    • 2004
  • The purpose of this study was to investigate the effects of green tea catechin on mixed function oxidase system (MFO), lipofuscin contents, carbonyl value, oxidative damage and the antioxidative defense system in lung of microwave exposed rats. Experimental groups were divided to normal group and microwave exposed group. The microwave exposed groups were subdivided into three groups: catechin free diet (MW-0C) group, 0.25% catechin (MW-0.25C) group and 0.5 % catechin (MW-0.5C) group according to the levels of dietary catechin supplementation. The rats were irradiated with microwave at frequency of 2.45 GHz for 15 min. Experimental animals were sacrificed at 6th day after microwave irradiation. The contents of cytochrome P$_{450}$ contents in MW-0C group was increased to 95% , compared with normal group. MW-0.25C and MW-0.5C groups were reduced to 16% and 31%, respectively, compared with MW-0C group. The activity of NADPH-cytochrome P$_{450}$ reductase in MW-0C group was increased to 44%, compared with normal group. MW-0.25C and MW-0.5C groups were reduced to 12% and 17%, respectively, compared with MW-0C group. The activity of superoxide dismutase (SOD) in MW-0C group was decreased to 21 %, compared with normal group. MW-0.25C and MW-0.5C group were significantly (p < 0.05) increased, compared with MW-0C group. The activity of glutathione peroxidase (GSHpx) in MW-0C group was significantly decreased, compared with normal group. MW-0.25C and MW-0.5C groups were recovered to the level of normal group. The thiobarbituric acid reactive substances (TBARS) content in MW-0C group was increased to 34 %, compared with normal group. Catechin supplementation groups were maintained the level of normal group. The levels of caybonyl value in MW-0C group was increased to 21 %, compared with normal group. MW-0.25C and MW-0.5C groups were reduced to 14% and 12%, respectively, compared with MW-0C group. The lipofuscin contents in MW-0C group were increased to 23.4 %, compared with normal group. That of MW-0.5C group was significantly reduced, compared with MW-0C group. In conclusion, MFO system was activated and the formation of oxidized protein, lipofuscin was increased and antioxidative defense system was weakened of lung tissue in microwave exposed rats, thus oxidative damage was increased. But it was rapidly recovered to normal level by green tea catechin supplementation.n.

Studies on the electrophoretic analysis of serum protein in Korean native calves (한우(韓牛) 송아지의 혈청단백분획(血淸蛋白分劃)에 관(關)한 연구(硏究))

  • Kim, Heung-seop;Lee, Joo-mook;Kwon, Oh-deog;Park, Jin-ho;Park, Sang-youel;Lee, Sung-ok
    • Korean Journal of Veterinary Research
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    • v.37 no.2
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    • pp.451-456
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    • 1997
  • 120 heads of korean native calves were examined of serum protein by using cellulose acetate electrophoresis. During 20 days since the calves were purchased, serum protein, fibrinogen values and plasma : fibrinogen ratio were examined in the calves with respiratory and diarrheal disease. The result obtained in this investigation were as follows : 1. Among the 120 heads of calves that were purchased from market, 14 heads(22%) of calves were occurred respiratory disease, and 12 heads(20%) of calves are occurred diarrhea. Occurrence of respiratory disease was 14.5(4~20) days in average and diarrhea was 9.6(2-15) days after they had been purchased. 2. Serum protein fraction were analyzed by cellulose acetate electrophoresis. ${\beta}-globulin$, A/G ratio and ${\beta}_2-globulin$ values were decreased in the calves with respiratory disease. Especially, ${\beta}_2-globulin$ were significantly decreased. In calves with diarrhea, there was no change in ${\beta}-globulin$ values. ${\beta}_2-globulin$ values were higher than that of the normal and respiratory diseased calves. 3. ${\alpha}-globulin$ values were increased in both of calves with diarrhea and respiratory disease. This tendency was due to increase ${\alpha}_2-globulin$ values. 4. The $\gamma$-globulin value of calves with diarrhea was the lowest among the 3 groups. 5. The total protein values of normal calves were $7.0{\pm}1.1g/dl$ and that of respiratory and diarrheal diseased calves were $6.9{\pm}0.9g/dl$ and $6.6{\pm}0.8g/dl$, respectively. Total protein value of calves with diarrhea was lower than that of normal and respiratory diseased calves. Globulin value of calves with diarrhea was the lowest among them. The low value of total protein in diarrheal diseased calves was due to decrease globulin values. 6. The fibrinogen values of calves with respiratory disease ($643{\pm}189mg/dl$) were significantly higher than that of normal calves($533{\pm}135mg/dl$) and calves with diarrhea($572{\pm}188mg/dl$). The plasma : fib. ratio of respiratory diseased calves was $12.0{\pm}4.9$, normal calves was $13.8{\pm}3.5$ and diarrheal diseased calves was $12.8{\pm}4.6$. The ratio of the calves with respiratory disease was significantly decreased.

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A FINITE DIFFERENCE APPROXIMATION OF A SINGULAR BOUNDARY VALUE PROBLEM

  • Lee, H.Y.;Ohm, M.R.;Shin, J.Y.
    • Bulletin of the Korean Mathematical Society
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    • v.35 no.3
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    • pp.473-484
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    • 1998
  • We consider a finite difference approximation to a singular boundary value problem arising in the study of a nonlinear circular membrane under normal pressure. It is proved that the rate of convergence is $O(h^2)$. To obtain the solution of the finite difference equation, an iterative scheme converging monotonically to the solution of the finite difference equation is introduced. And the numerical experiment of this method is given.

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