• Journal of Nutrition and Health
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• v.44 no.6
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• pp.474-480
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• 2011

Calcium (Ca) is an essential element to maintain body homeostasis. However, many factors disturb calcium absorption. Aspartic acid chelated calcium (AAC) was synthesized by new methods using calcium carbonate and aspartic acid. This study was carried out to investigate the bioavailability of AAC in Ca-deficient rats. The experimental groups were as follows: NC; normal diet control group, CD-C; untreated control group of Ca-deficient (CD) rats, CD-$CaCO_3$; $CaCO_3$ treated group of CD rats, CD-AAC; AAC treated group of CD rats, and CD-SWC; and seaweed-derived Ca treated group of CD rats. The Ca content of various types of Ca was held constant at 32 mg/day, and the four CD groups were fed for 7 days after randomized grouping. Ca content in serum, urine, and feces within feeding periods were analyzed to confirm Ca absorption. Serum Ca content was significantly higher in the CD-AAC (11.24 mg/dL) and CD-SWC (10.12 mg/dL) groups than that in the CD-C (8.6 mg/dL) group 2 hours following the first administration. The Ca content in feces was significantly lower in the CD-AAC (35.4 mg/3 days) and CD-SWC (71.1 mg/3 day) groups than that in the CD-$CaCO_3$ (98.7 mg/3 days) group (p > 0.05). AAC had a 2.3-fold higher absorption rate of Ca than that of SWC. No differences in fibula length were observed in the NC and CD groups. The fibula weights of the CD-AAC (0.33 g) and CD-SWC (0.33 g) groups increased compared to those in the CD-C (0.27 g) group; however, no significant difference was observed between the CD groups. We conclude that bioavailability of AAC is higher than that of seaweed-derived Ca or inorganic Ca. Thus, these findings suggest the AAC has potential as a functional food material related to Ca metabolism.

• Nutrition Research and Practice
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• v.14 no.6
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• pp.568-579
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• 2020

BACKGROUD/OBJECTIVES: Hepatic steatosis is the most common liver disorder, particularly in postmenopausal women. This study investigated the protective effects of standardized rice bran extract (RBS) on ovariectomized (OVX)-induced hepatic steatosis in rats. MATERIALS/METHODS: HepG2 cells were incubated with 200 µM oleic acid to induce lipid accumulation with or without RBS and γ-oryzanol. OVX rats were separated into three groups and fed a normal diet (ND) or the ND containing 17β-estradiol (E2; 10 ㎍/kg) and RBS (500 mg/kg) for 16 weeks. RESULTS: RBS supplementation improved serum triglyceride and free fatty acid levels in OVX rats. Histological analysis showed that RBS significantly attenuated hepatic fat accumulation and decreased hepatic lipid, total cholesterol, and triglyceride levels. Additionally, RBS suppressed the estrogen deficiency-induced upregulation of lipogenic genes, such as sterol regulatory element-binding protein 1 (SREBP1), acetyl-CoA carboxylase 1, fatty acid synthase, glycerol-3-phosphate acyltransferase, and stearoyl-CoA desaturase 1. CONCLUSIONS: RBS and γ-oryzanol effectively reduced lipid accumulation in a HepG2 cell hepatic steatosis model. RBS improves OVX-induced hepatic steatosis by regulating the SREBP1-mediated activation of lipogenic genes, suggesting the benefits of RBS in preventing fatty liver in postmenopausal women.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.24 no.1
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• pp.43-53
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• 2011

For reinforced concrete members, the bond strength is one of the important factors between two materials: concrete and reinforcing element. This study concerns the bond strength of deformed bars in artificial lightweight aggregate concrete by pull-out test. 144 cubic specimens were manufactured for the test. concrete compressive strength, size of deformed bar and embedment lengths were considered as variables in this study. Normal concrete with W/C ratio 50% specimens were tested for the comparison. Test results included the bond stress-slip responses and modes of failure. Bond strength increased with an increase of compressive strength of concrete according to W/C ratio. The equation of bond stress of polymer-modified lightweight aggregate concrete were proposed by regression analysis based on the result.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.31 no.3
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• pp.133-140
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• 2018

This paper is concerned with the 2-D micostructure generation for $Ni-A{\ell}_2O_3$ dual-phase composite materials and the numerical analysis of mechanical characteristic of hierarchical models of microstructure which are defined in terms of the scale of microstructure. The microstructures of dual-phase composite materials were generated by applying the mathematical RMDF(random morphology description functions) technique to a 2-D RVE of composite materials. And, the hierarchical models of microstructure were defined by the number of Gaussian points. Meanwhile, the volume fractions of metal and ceramic particles were set by adjusting the level of RMD functions. The microstructures which were generated by RMDF technique are definitely random even though the total number of Gaussian points is the same. The randomly generated microstructures were applied to a 2-D beam model, and the variation of normal and shear stresses to the scale of microstructure was numerically investigated. In addition, through the crack analyses, the influence of RMDF randomness and Gauss point number on the crack-tip stress is investigated.

• Journal of the Earthquake Engineering Society of Korea
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• v.21 no.2
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• pp.87-93
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• 2017

Many studies are conducted in several fields for fragility analysis of structures or elements which is a probabilistic seismic safety analysis in consideration with uncertainty of seismic loading. It is hard to directly conduct fragility analysis for an infrastructure with social importance due to its size. Therefore, a fragility analysis for an infrastructure mainly conducted in element level or conducted with scaled model built in accordance with similarity law. In this article, fragility analysis for prototype and scaled model of reinforced concrete column was conducted with numerical models which had been updated by the results of shaking table test and pseudo dynamic test. As a result, response stress from the numerical analysis result of prototype model was higher than that from scaled model due to different stiffness ratios between steel and concrete. However, the probability of failure for scaled model was higher than that for prototype model because failure criteria for scaled model was down due to similarity law. Also it was evaluated that probability of failure by using log normal standard deviation of response stresses by spectrum matched accelerograms was more reliable than probability of failure by using existing coefficient of variation normally used.

• Advances in concrete construction
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• v.6 no.2
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• pp.177-197
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• 2018

This paper presents a case study about the damages on the structural elements of a cast in place reinforced concrete (RC) building after a big fire which was able to be controlled after six hours. The fire broke off at the $2^{nd}$ basement floor of the building, which has five basements, one ground, and two normal floors. As a result of intensely stocked ignitable materials, it spread out to the all of the upstairs. In visual inspection, most of the typical fire damages were observed (such as spalling, net-like cracks, crumbled plasters, bared or visible reinforcement). Also, failures of the $2^{nd}$ basement columns were encountered. It has been concluded that the severity failures of the columns at the $2^{nd}$ basement caused utterly deformation of the building, which is responsible for the massive damages on the beam-column connections. All of the observed damages were categorized related to the types and presented separated regarding the floors. Besides to the visual inspection, the numerical analysis was run to verify the observed damaged on the building for columns, beams, and the connection regions. It is concluded from the study that several parameters such as duration of the fire, level of the temperature influence on the damages to the RC building. Also, it is highlighted by the study that if the damaged building is considered on the overall structural system, it is not able to satisfy the minimum service requirements neither gravity loads nor earthquake conditions.

• Smart Structures and Systems
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• v.20 no.4
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• pp.427-440
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• 2017

One of the suitable structural damage detection methods using vibrational characteristics are damage-index-based methods. In this study, a damage index for identifying damages in plate structures using frequency response function (FRF) data has been provided. One of the significant challenges of identifying the damages in plate structures is high number of degrees of freedom resulting in decreased damage identifying accuracy. On the other hand, FRF data are of high volume and this dramatically decreases the computing speed and increases the memory necessary to store the data, which makes the use of this method difficult. In this study, FRF data are compressed using two-dimensional principal component analysis (2D-PCA), and then converted into damage index vectors. The damage indices, each of which represents a specific condition of intact or damaged structures are stored in a database. After computing damage index of structure with unknown damage and using algorithm of lookup tables, the structural damage including the severity and location of the damage will be identified. In this study, damage detection accuracy using the proposed damage index in square-shaped structural plates with dimensions of 3, 7 and 10 meters and with boundary conditions of four simply supported edges (4S), three clamped edges (3C), and four clamped edges (4C) under various single and multiple-element damage scenarios have been studied. Furthermore, in order to model uncertainties of measurement, insensitivity of this method to noises in the data measured by applying values of 5, 10, 15 and 20 percent of normal Gaussian noise to FRF values is discussed.

• Journal of Microbiology and Biotechnology
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• v.27 no.4
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• pp.660-667
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• 2017

PineXol, extracted from Korean red pine bark, has beneficial effects, such as antioxidant, antiinflammatory, and antilipogenic activities in vitro. We tested the hypothesis that PineXol supplementation could have anti-obesity effects on mice fed a high-fat diet (HFD). Four-week-old male C57BL/6 mice were fed normal chow (18% kcal from fat) or a HFD (60% kcal from fat). HFD-fed animals were also subjected to PineXol treatment at a dose of 10 or 50 mg/kg body weight (BW) (PX10 or PX50, respectively) body weight. The body weight and body fat mass in the PX50 group were statistically lower than those in the HFD group (p < 0.05 and p < 0.001, respectively). The concentration of hepatic triglycerides, total cholesterol, and low-density lipoprotein cholesterol were reduced in the PX50 group compared with the HFD group (p < 0.01). Acetyl CoA carboxylase (p < 0.01), elongase of very long chain fatty acids 6 (p < 0.01), stearoyl CoA desaturase 1 (p < 0.05), microsomal triglyceride transfer protein (p < 0.01), and sterol regulatory element-binding protein 1 (p < 0.05) were significantly decreased in the PX50 group compared with that in the HFD group. In white adipose tissue, CCAAT-enhancer-binding protein alpha (p < 0.05), peroxisome proliferator-activated receptor gamma (p < 0.001), and perilipin (p < 0.01) were decreased in the PX50 group compared with those in the HFD group. Therefore, the current study implies the potential of PineXol for the prevention and/or amelioration of obesity, in part by inhibition of both hepatic lipid synthesis and adipogenesis in white adipose tissue.

• Korean Institute of Interior Design Journal
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• v.25 no.1
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• pp.201-212
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• 2016

This study is a literature study aimed to derive the evaluation factors for the survey of housing satisfaction of the physically handicapped. To attain the objective, the present study compared the influential factors of housing satisfaction for normal people and those for the physically handicapped found in the precedent researches, and analyzed them to draw out the evaluation factors for housing satisfaction of the physically handicapped. And then it drew out sub-factors and elements for the housing satisfaction of the physically handicapped. The evaluation factors for housing satisfaction of the physically handicapped are divided mainly into physical, social-psychological and economic factors. First, physical factor consists of 'functionality (usability)', 'safety', 'convenience', 'comfort', 'aesthetics', 'accessibility (mobility)', 'identifiability (recognition)'. Of them, 'functionality (usability)' factor consists of 3 sub-factors and 8 elements. 'Safety' was subdivided into securing safety and public order/crime prevention. and structural safety, and 7 elements were drawn out from 'safety'. 'Convenience' is sub-categorized into convenient usage and simple operation, and 9 elements were derived. 'Comfort' was classified into 2 sub-factors and 9 elements. 'Aesthetics' was classified into 2 sub-factors and elements. 'Accessibility (mobility)' was divided into 2 sub-factors and elements. 'Identifiability (recognition)' was classified into 2 sub-factors and 5 elements. Second, social-psychological factor includes 'sociality' and 'independence' factor. One sub-factor and one element were drawn from each of both factors. Third, 'economic factor' consists of 'economy'. One sub-factor and elements were drawn out from the factor. It is expected that the 10 evaluation factors, their sub-factors and elements that have been derived from this study can be used as the basic data and/or reference in designing residential space for the physically handicapped and making policy for it after verifying them in following studies. The present study finds itself significance in that the findings here can ultimately improve the housing welfare and life quality of the physically handicapped.

• Magazine of the Korea Concrete Institute
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• v.11 no.2
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• pp.177-186
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• 1999

The purpose of this study is to analyze the interface debonding of RC beams strengthened by carbon fiber sheet(CFS). The behavior of damaged RC beams strengthened with CFS is analytically investigated next using linear elastic fracture mechanics(LEFM) approach and the finite element method. The study includes an investigation of the separation mode by interface fracture of the strengthening materials due to the interfacial shear and normal stresses. The numerical method is presented to obtain the value of interfacial fracture parameter such as the strain energy release rate. Based on the results of this study, it is found that the critical case occurs when the interfacial cracks occur within a short region of the flexural crack. The CFS strengthening has not an adequate factor of safety against interfacial debonding of CFS. Furthermore, for the thicknesses of the adhesive studied[1mm~3mm], it is no noticeable effect on the strain energy release rate.