• Journal of Chest Surgery
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• v.10 no.2
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• pp.299-314
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• 1977

Clinical experience on 16 cases of open heart surgery under the extracorporeal circulation with mild or moderate hypothermia and partial hemodilution technique at the National Medical Center during the period from June 1976 to October 1977. Nine of sixteen were congenital heart disease and seven were acquired heart disease. The age of the patient ranged between 6 and 48 years. The body weight varied from 18.5kg to 60kg and body surface area 0. 79-1.70m2. The average priming volume of pump oxygenator was 2080 ml, which was consisted fresh ACD blood, buffered Hartmann`s solution, Mannitol, 50% dextrose in water and Vit. C. The average hemodilution rate was 27%. The average flow 2.3 L/min/m2 or 80 ml/min and the duration of perfusion varied from 31 min to 270 min with average of 107 min. The perfusion was carried out under the mild or moderate hypothermia using core cooling alone in 10 cases, core cooling and local myocardial cooling with $0-4^{\circ}C$ physiologic saline in 2 cases. From a hemodynamic point of view, the blood pressure dropped down around 80 mmHg after the initiation of perfusion follwed by increase to safety level and stable during the perfusion. The central venous pressure remained within normal limits. In most cases, hemoglobin and hematocrit decreased during and after the perfusion. Hemogiobin level was decreased, average of 20.6 %, hematocrit 18.6%, pletelets 55% postoperatively. Plasma hemoglobin increased moderately, from preperfusion average valve of 7.79 mg % to post-perfusion value of 54.7 mg %. Electrolytes changes during cardiopulmonary bypass showed definite hypokalemia but changes of Na, Ca were not definite. Arterial blood gas analysis during cardiopulmonary bypass suggested that the metabolic acidosis which was accompanied by respiratory alkalosis which was corrected postoperatively. As the opera tive complication, transient hemoglobinuria in 4 cases and neurological signs in 2 cases were all cured. There were 2 death cases and operative mortality rate was 12.5%.

• The Journal of the Korea Contents Association
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• v.15 no.9
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• pp.329-341
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• 2015

The purpose of this study was to identify the types of subjectivity on communication styles of nursing freshmen and explore their properties by using the Q Methodology. Fifty nursing freshmen of P sample classified 55 Q-statements into the normal distribution of 11 point scale. Data were collected from May to June, 2015 and analyzed by using PC-QUANL program. As a result, communication styles are identified as 'Open-interaction facilitator', 'Other-considerate listener', 'Tense-sensitive to criticism person', and 'Non-interactive observer'. Open-interaction facilitators proficiently use verbal and nonverbal expressions, openly disclosing themselves and facilitating interactions with others. Other-considerate listeners primarily consider others before themselves, with careful communication. Tense-sensitive to criticism persons are nervous, sensitive to criticism, and are distractive style, so they have difficulties in intimate interaction with others. Non-interactive observers are bystanders who observe others and feel indifferent to interactions, without any self disclosure. The result of this study will be used for developing communication educational programs for nursing freshmen.

• The Journal of Korean Association of Computer Education
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• v.13 no.6
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• pp.91-98
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• 2010

NAC(Network Access Control) has been developed as a solution for the security of end-point user, to be a target computer of worm attack which does not use security patch of OS and install Anti-Virus, which spreads the viruses in the Intra-net. Currently the NAC products in market have a sufficient technology of pre-connect, but insufficient one of post-connect which detects the threats after the connect through regular authentication. Therefore NAC users have been suffered from Zero-day attacks and malware infection. In this paper, to solve the problems in the post-connect step we generate the normal behavior profiles using the traffic information of each host, host information through agent, information of open port and network configuration modification through network scanner addition to authentication of host and inspection of policy violation used before. Based on these we propose the system to detect the hosts infected malware.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.26 no.1
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• pp.169-176
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• 2016

Android platform is designed to be user-friendly, yet sometimes its convenience introduces vulnerabilities that normal users cannot justify. In this paper, after making an overview of popular open source analysis tools for android applications, we point out the dangerous use of Permission Group in current Google Policy, and suggest a technique to mitigate the risks of privilege escalation that attackers are taking advantage of. By conducting the investigation of 21,064 malware samples, we conclude that the proposed technique is considered effective in detecting insecure application update, as well as giving users the heads-up in security awareness.

• Structural Engineering and Mechanics
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• v.42 no.1
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• pp.121-129
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• 2012

All contemporary seismic Codes have adopted smooth design acceleration response spectra, which have derived by statistical analysis of many elastic response spectra of natural accelerograms. The above smooth design spectra are characterized by two main branches, an horizontal branch that is 2.5 times higher than the peak ground acceleration, and a declining parabolic branch. According to Eurocode EN/1998, the period range of the horizontal, flat branch is extended from 0.1 s, for rock soils, up to 0.8 s for softer ones. However, from many natural recorded accelerograms of important earthquakes, the real spectral amplification factor appears to be much higher than 2.5 and this means that the spectrum leads to an unsafe seismic design of the structures. This point is an issue open to question and it is the object of the present study. In the present paper, the spectral amplification factor of the smooth design acceleration spectra is re-calculated on the grounds of a known "reliability index" for a desired probability of exceedance. As a pilot scheme, the seismic area of Greece is chosen, as it is the most seismically hazardous area in Europe. The accelerograms of the 82 most important earthquakes, which have occurred in Greece during the last 38 years, are used. The soil categories are taken into account according to EN/1998. The results that have been concluded from these data are compared with the results obtained from other strong earthquakes reported in the World literature.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2017.05a
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• pp.218-223
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• 2017

This paper deals with a fault diagnosis algorithm using the Kalman filter for a 75-ton Liquid Propellant Rocket Engine (LPRE). To design the Kalman filter, we linearized a non-linear simulation model of a 75-ton LPRE at an operating point, and checked the performance of the Kalman filter by comparing the measured values with estimated values of the states. Then, we artificially injected a fault of the turbopump efficiency into the simulation to confirm the performance of the fault diagnosis algorithm with the developed Kalman filter by comparing the variation of the residuals of the normal state with that of the fault cases.

• BMB Reports
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• v.40 no.5
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• pp.715-722
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• 2007

A new full-length cDNA encoding hyoscyamine $6\beta$-hydroxylase (designated as aah6h, GenBank Accession No. EF187826), which catalyzes the last committed step in the scopolamine biosynthetic pathway, was isolated from young roots of Anisodus acutangulus by rapid amplification of cDNA ends (RACE) for the first time. The full-length cDNA of aah6h was 1380 bp and contained a 1035 bp open reading frame (ORF) encoding a deduced protein of 344 amino acid residues. The deduced protein had an isoelectric point (pI) of 5.09 and a calculated molecular mass of about 38.7 kDa. Sequence analyses showed that AaH6H had high homology with other H6Hs isolated from some scopolamine-producing plants such as Hyoscyamus niger, Datura metel and Atropa belladonna etc. Bioinformatics analyses results indicated AaH6H belongs to 2-oxoglutarate-dependent dioxygenase superfamily. Phylogenetic tree analysis showed that AaH6H had closest relationship with H6H from A. tanguticus. Southern hybridization analysis of the genomic DNA revealed that aah6h belonged to a multi-copy gene family. Tissue expression pattern analysis firstly founded that aah6h expressed in all the tested tissues including roots, stems and leaves and indicated that aah6h was a constitutive-expression gene, which was the first reported tissue-independent h6h gene compared to other known h6h genes.

• The Korean Journal of Malacology
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• v.32 no.4
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• pp.241-247
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• 2016

Macrophage Migration Inhibitory Factor (MIF) are well-defined role as unique cytokine and critical mediator in acute and chronic inflammatory diseases, autoimmune diseases. In this study, we isolated and characterized a full-length of MIF cDNA from the abalone (Haliotis discus hannai). The full-length cDNA of abMIF was of 1264 bp, consisting of a 5'-terminal UTR of 143 bp, an open reading frame of 360 bp and a 3-terminal UTR of 761 bp. The abalone MIF cDNA encodes a 119-amino acid polypeptide with a calculated molecular mass of 13.4 kDa and isoelectric point of 9.07. Multiple alignments and phylogenetic analysis with the deduced abalone MIF protein and showed strong homology with disk abalone (Haliotis discusdiscus). The deduced amino acid sequence of abMIF exhibited homology with other reported MIFs, such as 80%, with that of other disk abalone H. discus discus MIF gene. Quantitative real-time PCR (qRT-PCR) analysis indicated that abMIF was highly expression observed in hapatopacreas, intestine, foot, and gonad of normal conditioned abalone. Even though AbMIF mRNA level in hemocytes was low under the normal condition, it was sharply up-regulated and reached the maximum at 6 h post-infection with Vibrio parahaemolyticus, and then decreased at 24 h post-infection. This result indicates that abMIF plays an important role in responding in the innate immune system.

• Journal of East-West Nursing Research
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• v.3 no.1
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• pp.7-16
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• 1998

This paper reviewed the concept of the energy flow in east and west. The differences in the views of the energy flow between oriental and western thought were compaired according to the ontological point of view. Human body take up energy and material on open system which maintains homeostasis. Human and environment are continuously interacting in a state of co-existence. Human has energy field called "aura" and seven chakra in energy outflow moving came as meridian. Qi is an invisible cosmic energy helping the fundamental human activity and changes. The basic action of Qi is helping the human growth and development, maintain the body temperature and preventing the intrusion of microorganism. In the normal healthy organism, all are maintained in balance and in a continuous circulation of Qi, while illness is the result of the disturbed Qi flow in the aspect of Qi-theory. Although there are differences between oriental and western medicine in approaches to clients, the basic point of view and philosophy have many similarities on fundamental level. An understanding of the basic thought of energy flow and oriental concept of energy flow implies a more comprehensive meaning than the perspective of unitary transformation discussed in modern western thought of energy flow. Now we should avoid narrow view of energy concept and regard energy flow as an integrated concept with Korean culture. Regarding Qi-theory which provides a comprehensive and humanistic and ethical foundation for nursing philisophy through this overview, it is hoped that a contribution will be made to the development of nursing intervention which is suitable to Korean context.

• Transactions of the Korean Society of Pressure Vessels and Piping
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• v.9 no.1
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• pp.15-19
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• 2013

The auxiliary feedwater is an important to remove the heat from the reactor core when the main feedwater system is unavailable. In most initiating events in Probabilistic Safety Assessment(PSA), the operaton of this system is required to mitigate the accidents. For one of domestic nuclear power plants, a design change of a turbine-driven auxiliary feedwater pump(TD-AFWP), pipe, and valves in the auxiliary system is implemented due to the aging related deterioration by long time operation. This change includes the replacement of the TD-AFWP, the relocation of some valves for improving the system availability, a new cross-tie line, and the installation of manual valves for maintenance. The design modification affects the PSA because the system is critical to mitigate the accidents. In this paper, the safety effect of the change of the auxiliary feedwater system is assessed with regard to the PSA view point. The results demonstrate that this change can supply the auxiliary feedwater from the TD-AFWP in the accident with the motor-driven auxiliary feedwater pump(MD-AFWP) unavailable due to test or maintenance. In addition, the change of MOV's normal position from "close" to "open" can deliver the water to steam generator in the loss of offsite power(LOOP) event. Therefore, it is confirmed that the design change of the auxiliary feedwater system reduces the total core damage frequency(CDF).