• Title/Summary/Keyword: Nonspecific

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Bronchial Hyperresponsiveness in Chronic Renal Failure Undergoing Hemodialysis (만성 신부전 환자에서 혈액투석 전후의 기관지 과민반응검사)

  • Hwang, Young-Sil;Shim, Dae-Suk
    • Tuberculosis and Respiratory Diseases
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    • v.42 no.4
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    • pp.548-554
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    • 1995
  • Background: Cardiogenic pulmonary edema increases nonspecific airway responsiveness in humans and animals. Increased extravascular lung water from overt pulmonary edema to subclinical interstitial edema is a common finding in patients with chronic renal failure. Several studies carried out to assess pulmonary function disturbances in this condition have documented a reduction in forced expiratory volume that usually reverses after hemodialysis, suggesting airway edema as the underlying mechanism. This interstitial edema may also lead to nonspecific bronchial hyperresponsiveness. We hypothesized that patients with chronic renal failure may present nonspecific bronchial hyperresponsiveness due to subclinical interstitial pulmonary edema. Methods: We studied 18 chronic renal failure undergoing regular hemodialysis 3 times a week(New York Heart Association Class II) without concomittent disease. These patients were checked pulmonary function test and metacholine provocation test before hemodialysis and same procedure was repeated if responsive, after hemodialysis. Results: 1) 12 out of 18 patients before hemodialysis were reactive in metacholine provocation test(66.7%) before hemodialysis. This airway hyperresponsiveness were decreased after hemodialysis. 2) Pulmonary function was improved after hemodialysis and change in $FEV_1$ was correlated with change in weight(r=-0.62, p<0.01). 3) There was a close correlation between log $PD_{20}$ and $FEF_{25}$, which is one of the variables of the peripheral airways(r=0.58, p<0.05). Conclusion: We speculated interstitial pulmonary edema may play a significant role in bronchial hyperresponsiveness and lung function impaired in patients with chronic renal failure.

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Congenital Cystic Lung Combined with Pulmonic Valvular Stenosis: A Case Report (선천성 낭성폐와 동반한 폐동맥판막협착증: 1례 보고)

  • 김주이
    • Journal of Chest Surgery
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    • v.10 no.1
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    • pp.118-123
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    • 1977
  • Congenital cystic disease of the lung is very rare and controversial disease. But in general is regarded as developmental anomaly. Occasionally failure of the primitive lung bud to develop combined with cardiac anomaly had been reported but it was very rare. Recently a case of cystic lung disease combined with pulmonic valvular stenosis was seen in this clinic with clinical pictures of nonspecific respiratory infection and X-ray finding very similar to that of far advanced pulmonary tuberculosis, destroyed left lung. This case was treated by closed pulmonic valvulotomy and left side pneumonectomy successfully.

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Traumatic Pseudocyst of Lung by Blunt Trauma (흉부둔상에 의한 외상성 가성 폐기낭)

  • 김욱진
    • Journal of Chest Surgery
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    • v.23 no.5
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    • pp.1014-1016
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    • 1990
  • Pseudocysts of lung by blunt chest trauma are rare lesion with 1 to 2 % incidence. The symptoms are nonspecific and misled or confused with lung abscess or congenital cystic disease of lung occasionally. Diagnosis is not difficult by radiographic findings and history of blunt chest trauma. There courses are benign and spontaneously absorbed and require no specific treatment mostly. Recently, we had the one case of 8 year-old female with traumatic lung cyst and its cavities filled the entire right lower lobe. The destruction of lung was severe, so, right lower lobectomy was done and recovered, discharged without event.

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Gastric Pseudotumoral Lesion Caused by a Fish Bone Mimicking a Gastric Submucosal Tumor

  • Kim, Se Won;Kim, Sang Woon;Song, Sun Kyo
    • Journal of Gastric Cancer
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    • v.14 no.3
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    • pp.204-206
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    • 2014
  • Gastric complications following unintentional foreign body ingestion are extremely rare. Here, we report the case of a 59-year-old healthy woman who presented with nonspecific abdominal pain and an apparent gastric submucosal tumor that was incidentally detected by gastrofiberscopy. The patient underwent laparoscopic surgery, which revealed an intact gastric wall with no tumor invasion, deformity, or evidence of a gastric submucosal lesion. However, an impacted fish bone was found.

Effect of Alisols Isolated from Alisma orientale Jazep. Against Several Agonists in Isolated Rat Ileum (택사의 Alisol성분들이 몇가지 Agonist에 의한 적출장관 수축에 미치는 영향)

  • YunChoi, Hye-Sook;Chung, Sung-Hyun;Kim, Young-Sook
    • Korean Journal of Pharmacognosy
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    • v.12 no.4
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    • pp.200-202
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    • 1981
  • Alisol B(II) and alisol B monoacetate (III) isolated from the rhizome of Alisma orientale Jazepczuk (Alismataceae) showed antagonistic effects against the contractions induced by angiotensin and bradykinin in rat ileum. However, they seem to be nonspecific antagonism.

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Bacillus cereus에 의한 Phospholipase C (PLC) 생산

  • Seo, Guk-Hwa;Lee, Jong-Il;Bornscheuer, Uwe T.
    • 한국생물공학회:학술대회논문집
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    • 2002.04a
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    • pp.232-234
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    • 2002
  • Bacillus cereus secretes a nonspecific phospholipase C (PLC) that catalyzes the hydrolysis of phospholipids to yield diacylglycerol and a phosphate monoester. This study focuses on the production of PLC by B. cereus and recombinant E. coli with fusion protein gene (plc::gfp). Fermentation processes have been monitored by a 2-dimensional fluorescence sensor.

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Lung Actinomycosis - A Report of one Case - (폐방선균증;1례 보고)

  • Im, Seung-U;Lee, Jeong-Cheol;Han, Seung-Se
    • Journal of Chest Surgery
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    • v.24 no.12
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    • pp.1220-1224
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    • 1991
  • A 39 year-old woman presenting with a hemoptysis, pulmonary infiltrate was found to have thoracic actinomycosis by the specimens of excised lung. Recently, pulmonary actinomycosis is very rare by the widespread use of antibiotics. Clinical, radiological, and microbiological findings can be nonspecific. The diagnosis is dependent on a high index of suspicion. Chances for cure are excellent with lengthy antibiotic administration. The purpose of this paper is to review our experience and to remind us of pulmonary actinomycosis.

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Protease released during germination of dictyostelium discoideum spores (Dictyostelium discoideum의 포자가 발아중에 유출하는 protease에 관하여)

  • 윤경하;윤철호
    • Korean Journal of Microbiology
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    • v.27 no.1
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    • pp.43-47
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    • 1989
  • Characteristics and roles of protease released during the germination of Dictyostelium discoideum spores were investigated. When geat activated, the spores germinated, progressively releasing the protease into the extracellular medium. The protease activity exhibited high at pH 2.5. When cyclogeximide was added to culture, complete germination (emergence) and protease release were stopped. Addition of purified nonspecific protease to culture speeded up germination. These results suggest that excreted protease may play a role in removal of the spore wall.

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Pityriasis Rosea in Pig: A Case Report (돼지의 장미비강진(薔薇秕糠疹) 일례(一例))

  • Kwon, Nam Suk;Park, Young Jun;Lee, Chung Gil
    • Korean Journal of Veterinary Research
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    • v.19 no.2
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    • pp.159-160
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    • 1979
  • Pityriasis rosea in a 2-month old pig is described. Lesions were confined to the abdomen and groin. They consisted of raised, erythematous papules with distinct borders. Microscopic examination of the lesions revealed a nonspecific dermatitis with acanthosis, moderate infiltration of mononuclear cells and eosinophils in the upper dermis. The known occurrence of the disease will help differentiate the condition from other dermatoses.

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Delayed diagnosis of intramedullary spinal cord germinoma

  • Kim, Haelim;Lee, Eung-Joon;Sung, Jung-Joon
    • Annals of Clinical Neurophysiology
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    • v.22 no.2
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    • pp.109-111
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    • 2020
  • Germ-cell tumors (GCTs) are common in the central nervous system. GCTs are highly sensitive to radiotherapy and chemotherapy and can be cured without radical surgery. However, this tumor produces nonspecific imaging findings, and its rarity can make diagnosis challenging. Here we report a case in which the first diagnosis was uncertain and follow-up imaging revealed intramedullary germinoma. The patient underwent chemotherapy and radiotherapy after the diagnosis.