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The effects of low dose doxycycline regimen on gingival crevicular fluid enzyme actmty of diabetic patients with periodontitis and adult periodontitis patients (저용량 독시싸이클린 투여가 당뇨환자 마치 성인성 치주염 환자의 치은열구액내 효소 활성도에 미치는 영향에 관한 비교연구)

  • Jeong, Seong-Nyum;Han, Soo-Boo
    • Journal of Periodontal and Implant Science
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    • v.27 no.4
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    • pp.701-722
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    • 1997
  • It was reported that low dose doxycycline(LDD) regimen could inhibit pathologically elevated collagenase activity in the gingival crevicular fluid of petients with adult periodontitis without producing typical antibiotic side effects. The purpose of this study was to evaluate the effects of LDD regimen(20mg) administered during non-surgical therapy on clinical index and gingival crevicular fluid enzyme activity in diabetics who are at high risk for periodontal disease. Forty-nine subjects having at least two sites with probing pocket depths greater than 4mm were selected. In this double-blind, placebo-controlled study, the patients were administered 20 mg doxycycline capsule or placebo capsule b.i.d. for 2 weeks. Clinical parameters of dental plaque, gingival inflammation, probing pocket depth and probing attachment level were assessed at week 0, 2, 4, and 8. Gingival crevicular fluid samples were collected at the same time to evaluate the activities of collagenase and elastase. Clinical parameters and elastase activity were significantly reduced in all groups compared to the baseline value after treatment. Significantly greater reduction in pocket depth and gain in attachment level was shown in the LDD-administered group compared to placebo group in both adult periodontitis and diabetic patients. Total collagenase activity was also reduced significantly in all groups after treatment, but the greater reduction was seen in the LDD-administered diabetics group compared to relevant placebo group(at 4, 8week). Significantly greater reduction in active collagenase activity was also seen in the LDD-administered group compared to placebo group in diabetic patients(at 2, 4, 8week). These results indicated that use of low dose doxycycline could be aueseful adjunct to instrumentation therapy in the management of diabetic patient with periodontitis as well as adult periodontitis patient.

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Development of Multisite Spatio-Temporal Downscaling Model for Rainfall Using GCM Multi Model Ensemble (다중 기상모델 앙상블을 활용한 다지점 강우시나리오 상세화 기법 개발)

  • Kim, Tae-Jeong;Kim, Ki-Young;Kwon, Hyun-Han
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.35 no.2
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    • pp.327-340
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    • 2015
  • General Circulation Models (GCMs) are the basic tool used for modelling climate. However, the spatio-temporal discrepancy between GCM and observed value, therefore, the models deliver output that are generally required calibration for applied studies. Which is generally done by Multi-Model Ensemble (MME) approach. Stochastic downscaling methods have been used extensively to generate long-term weather sequences from finite observed records. A primary objective of this study is to develop a forecasting scheme which is able to make use of a MME of different GCMs. This study employed a Nonstationary Hidden Markov Chain Model (NHMM) as a main tool for downscaling seasonal ensemble forecasts over 3 month period, providing daily forecasts. Our results showed that the proposed downscaling scheme can provide the skillful forecasts as inputs for hydrologic modeling, which in turn may improve water resources management. An application to the Nakdong watershed in South Korea illustrates how the proposed approach can lead to potentially reliable information for water resources management.

A Study on the Seam Tracking by Using Image Processing (영상정보처리에 의한 용접선 추적에 관한 연구)

  • 배철오;박영산;이성근;김윤식;안병원;김현수
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2001.05a
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    • pp.460-464
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    • 2001
  • Recently, the use of Robot increase little by little for the purpose of developing a welding quality and productivity in the arc welding part. It is more important to contact the seam for arc welding before moving a welding robot. There are two types of method to contact the seam namely contact and noncontact type largely In this paper, image processing sensor(a kind of non-contact sensor) is concerned to track the seam by using laser diode and CCD camera. A structured laser diode's light illuminated on the weld groove and the reflected shape is introduced by CCD camera. The image board captures this image and software analyzes this image. The robot is moved and welded exactly as acquired image X-Y data is changed with robot's X-Y value. Also, most of seam tracking are considered by changing the program simply in case of the different weld prove of plane surface.

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A Light Incident Angle Stimulated Memristor Based on Electrochemical Process on the Surface of Metal Oxide

  • Park, Jin-Ju;Yong, Gi-Jung
    • Proceedings of the Korean Vacuum Society Conference
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    • 2014.02a
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    • pp.174-174
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    • 2014
  • Memristor devices are one of the most promising candidate approaches to next-generation memory technologies. Memristive switching phenomena usually rely on repeated electrical resistive switching between non-volatile resistance states in an active material under the application of an electrical stimulus, such as a voltage or current. Recent reports have explored the use of variety of external operating parameters, such as the modulation of an applied magnetic field, temperature, or illumination conditions to activate changes in the memristive switching behaviors. Among these possible choices of signal controlling factors of memristor, photon is particularly attractive because photonic signals are not only easier to reach directly over long distances than electrical signal, but they also efficiently manage the interactions between logic devices without any signal interference. Furthermore, due to the inherent wave characteristics of photons, the facile manipulation of the light ray enables incident light angle controlled memristive switching. So that, in the tautological sense, device orienting position with regard to a photon source determines the occurrence of memristive switching as well. To demonstrate this position controlled memory device functionality, we have fabricated a metal-semiconductor-metal memristive switching nanodevice using ZnO nanorods. Superhydrophobicity employed in this memristor gives rise to illumination direction selectivity as an extra controlling parameter which is important feature in emerging. When light irradiates from a point source in water to the surface treated device, refraction of light ray takes place at the water/air interface because of the optical density differences in two media (water/air). When incident light travels through a higher refractive index medium (water; n=1.33) to lower one (air; n=1), a total reflection occurs for incidence angles over the critical value. Thus, when we watch the submerged NW arrays at the view angles over the critical angle, a mirror-like surface is observed due to the presence of air pocket layer. From this processes, the reversible switching characteristics were verified by modulating the light incident angle between the resistor and memristor.

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Intelligent Range Decision Method for Figure of Merit of Sonar Equation (소나 방정식 성능지수의 지능형 거리 판단기법)

  • Son, Hyun Seung;Park, Jin Bae;Joo, Young Hoon
    • Journal of the Korean Institute of Intelligent Systems
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    • v.23 no.4
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    • pp.304-309
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    • 2013
  • This paper proposes a intelligent approach on range decision of figure of merit. Unknown range of the underwater target and the non-fixed signal excess make the uncertainty for the tracking process. Using the input data of signal excess related to the range, we establish the rule of the fuzzy set and the original data acquired by sonar can be transformed to the fuzzified data set. To reduce the error arisen from the unexpected data, we use the new data transformed in fuzzy set. The piecewise relations of the min value, max one, and the mean one are calculated. The three values are used for the expected range of the underwater target. By analysing the fluctuation of the data, we can expect the target's position and the characteristics of the maneuvering. The examples are presented to show the performance and the effectiveness of the proposed method.

Effect of Flask Type on the Production of Value-added Hydroxy Fatty Acid by Pseudomonas aeruginosa PR3 (Pseudomonas aeruginosa PR3에 의한 기능성지방산 Hydroxy fatty acid 생산에 있어 배양용기 형태에 따른 영향)

  • Baek, Ka-Yeon;Son, Hye-Ran;Kim, Hak-Ryul
    • Journal of the Korean Applied Science and Technology
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    • v.27 no.2
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    • pp.114-122
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    • 2010
  • Hydroxy fatty acids have gained important attentions because of their special properties such as higher viscosity and reactivity compared to non-hydroxy fatty acids. The new bacterial isolate Pseudomonas aeruginosa (PR3) had been well studied to produce mono-, di-, and tri-hydroxy fatty acids from different unsaturated fatty acids. Of those hydroxy fatty acids, 7,10-dihydroxy-8(E)-octadecenoic acid (DOD) was produced with high yield from oleic acid by P. aeruginosa PR3. Mostly, the substrates used for the production of hydroxy fatty acid by microorganisms were free fatty acids or synthetic lipids. However, it is highly plausible to use vegetable oils containing oleic acid such as olive oil for DOD production by P. aeruginosa PR3. As a first step to address the utilization of olive oil as a substrate for DOD production, we tried to determine the effect of vessel type on DOD production from olive oil by P. aeruginosa PR3. Of two different flask types of normal flask and baffled-flask, baffled-flask was highly effective for DOD production with all the media tested. Maximum increase of productivity by baffled-flask represented 221% with the medium supplemented with whey powder instead of lactose. Results from this study demonstrated that vessel type and medium composition could be both significant factors for DOD production from olive oil by P. aeruginosa PR3.

Use of Chlorophyll a Fluorescence Imaging for Photochemical Stress Assessment in Maize (Zea mays L.) Leaf under Hot Air Condition

  • Park, Jong Yong;Yoo, Sung Young;Kang, Hong Gyu;Kim, Tae Wan
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.61 no.4
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    • pp.270-276
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    • 2016
  • The objective of this study was to find a rapid determination of the hot air stress in maize (Zea mays L.) leaves using a portable chlorophyll fluorescence imaging instrument. To assess the photosynthetic activity of maize leaves, an imaging analysis of the photochemical responses of maize was performed with chlorophyll fluorescence camera. The observed chlorophyll imaging photos were numerically transformed to the photochemical parameters on the basis of chlorophyll a fluorescence. Chlorophyll a fluorescence imaging (CFI) method showed that a rapid decrease in maximum fluorescence intensity ($F_m$) of leaf occurred under hot air stress. Although no change was observed in the maximum quantum yield ($F_v/F_m$) of the hot air stressed maize leaves, the other photochemical parameters such as maximum fluorescence intensity ($F_m$) and Maximum fluorescence value ($F_p$) were relatively lowered after hot air stress. In hot air stressed maize leaves, an increase was observed in the nonphotoquenching (NPQ) and decrease in the effective quantum yield of photochemical energy conversion in photosystem II (${\Phi}PSII$). Thus, NPQ and ${\Phi}PSII$ were available to be determined non-destructively in maize leaves under hot air stress. Our results clearly indicated that the hot air could be a source of stress in maize leaves. Thus, the CFI analysis along with its related parameters can be used as a rapid indicating technique for the determining hot air stress in plants.

Temperature Analysis for Welding Part of Capstan Drum using Finite Element Method (유한요소법을 이용한 캡스턴 드럼의 용접부 온도해석)

  • 김옥삼
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.36 no.4
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    • pp.322-328
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    • 2000
  • Welding means that metal parts are joined by melting (with or without a filler material) or that new material is added to a metal part by melting. Welding of metal parts is an important technology method in manufacturing processes of capstan drum for costal vessels. Thermal stresses due to the non-uniform temperature fields during welding influence both the fabrication and the use of the weldment. In the problem of this thermal effect, particularly it is a well known that analysis for temperature gradient, temperature distribution, and the like become consequence factors to a safety and a strength design. This paper analyzes the temperature distribution of welding part in capstan drum for the inshore and costal vessels using finite element method. At early stage of the cooling after welding processes, the abrupt temperature gradient has been shown in vicinity of the bottom face of welding part. Therefore it calculates the numerical value that can be applied to the optimal design of welding parts in the shapes for capstan drum.

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Effects of Slime Program on Hand Function and Problem Behavior of Adults with Intellectual Disabilities

  • Jang, Woo-Hyuk;Kim, Su-Hyun;No, Seo-Yeong;Moon, Ji-Yeong;Lee, Eun-Byeol;Jeon, Se-Hyun
    • The Journal of Korean Physical Therapy
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    • v.32 no.4
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    • pp.250-257
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    • 2020
  • Purpose: This study examined the effects of training using the slime on the hand function and problem behavior in adults with intellectual disabilities. Methods: Five adults with intellectual disabilities who were judged as Level 1 or Level 2 were selected. The training consisted of one session (50 min)/day, one day/week for 10 weeks (preparatory activities: 5 min, slime activities: 40 min, finishing activities: 5 min) The functions of the hand (Purdue Pegboard Test [PPT], grip strength test [GST]) and problem behavior (Korean Behavior Problems Inventory [KBPI]) were assessed three times (first assessment; pre, second assessment; post-5 weeks, third assessment; post-10 weeks). Wilcoxon signed-rank tests were used to analyze changes in the subjects' performance before and after the intervention. Results: In the PPT, the use of the non-dominant hand was increased significantly (p<0.05). No significant differences were observed in the remaining results, but the mean value increased. In addition, although the problem behavior was not statistically significant, an increase in the problem behavior score was noted. Conclusion: The training using the slime for adults with intellectual disabilities is effective in hand function improvement and reducing problem behavior.

A Study For the Standardization Design of Ginseng Cultivating Facility for the Improvement of Farming Environment (영농환경 개선을 위한 인삼재배사 표준화 디자인)

  • 신택균
    • Archives of design research
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    • v.16 no.1
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    • pp.93-102
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    • 2003
  • This thesis is a study for the standardization of the design of ginseng cultivating facility (also known as the sun off facility) for the improvement of farming environment. The core background of this study is to propose a basic study for introducing, for the first time, the modern ginseng cultivating facility that matches the position of korea as a main nation cultivating ginseng and to secure the production and quality value of Koryo Ginseng, which is a special world-level agricultural product of Korea, under the present WTO agricultural product open system. Right now, wood, rice straw, or vinyls, which are non-standardized or are for one-time use only are used. Therefore, as a concept of the design, 1 tried to revise the fact that these materials are being used to set up the facility repeatedly every year which is creating environmental pollution and wasting of our countries labor and resource. Concrete factors to be improved are as follows: First, standardization of the form and structure of mass production system; Second, introduction of new materials such as semi-permanent resin etc., for standardization of materials; 1 tried to make the above two factors into a shape based on a Korean image. As for the design, designed a standard unit model of the ginseng cultivation facility especially keeping in mind to design it so the facility can be freely connected and assembled according to the size and shape of the cultivation area.

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