• Molecular & Cellular Toxicology
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• v.3 no.3
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• pp.198-207
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• 2007

[ $^{18}F$ ]-fluorodeoxyglucose (FDG) uptake on positron emission tomography (PET) scan has been found to reflect tumor aggressiveness and prognosis in various types of cancer. In this study, the gene expression profiles of glial tumors were evaluated to determine whether glial tumors with high $^{18}F$-FDG uptake have more aggressive biological potential than with low uptake. Surgical specimens were obtained from the 12 patients with glial tumors (4 males and 8 females, age range 42-68 years). The tumor samples were divided into two groups based on the $^{18}F$-FDG uptake PET scan findings: high $^{18}F$-FDG uptake (n=4) and low $^{18}F$-FDG uptake (n=8). The pathological tumor grade was closely correlated with the $^{18}F$-FDG uptake pattern: Glial tumors with high $^{18}F$-FDG uptake were pathologically Edmondson-Steiner grade III, while those with low uptake were grade II. The total RNA was extracted from the frozen tissues of all glial tumors (n=12), and adjacent non-cancerous tissue (n=3). The gene expression profiles were evaluated using cDNA microarray. The glial tumors with high $^{18}F$-FDG uptake showed increase expression of 15 genes compared to those with low uptake (P<0.005). Nine genes were down-regulated. Gene expression is closely related to cell survival, cell-to-cell adhesion or cell spreading; therefore, glial tumors with high $^{18}F$-FDG uptake appear to have more aggressive biological properties than those with low uptake.

• Fire Science and Engineering
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• v.13 no.1
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• pp.37-47
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• 1999

The spreading fire of very small floating particles after they are ignited is fast and t therefore dangerous. The research on this area has been limited to experiments and global simulations which treat them as dusts or gaseous fuel with certain concentration well m mixed with air. This research attempted micro-scale analysis of ignition of those particles modeling them as liquid droplets. For the beginning, the in-line array of fuel droplets is modeled by two-dimensional, unsteady conservation equations for mass, momentum, energy and species transport in the gas phase and an unsteady energy equation in the liquid phase. They are solved numerically in a generalized non-orthogonal coordinate. The single step chemical reaction with reaction rate controlled by Arrhenius’ law is assumed to a assess chemical reaction numerically. The calculated results show the variation of temperature and the concentration profile with time during evaporation and ignition process. Surrounding oxygen starts to mix with evaporating fuel vapor from the droplet. When the ignition condition is met, the exothermic reactions of the premixed gas initiate a and burn intensely. The maximum temperature position gradually approaches the droplet surface and maximum temperature increases rapidly following the ignition. The fuel and oxygen concentration distributions have minimum points near the peak temperature position. Therefore the moment of ignition seems to have a premixed-flame aspect. After this very short transient period minimum points are observed in the oxygen and fuel d distributions and the diffusion flame is established. The distance between droplets is an important parameter. Starting from far-away apart, when the distance between droplets decreases, the ignition-delay time decreases meaning faster ignition. When they are close and after the ignition, the maximum temperature moves away from the center line of the in-line array. It means that the oxygen at the center line is consumed rapidly and further supply is blocked by the flame. The study helped the understanding of the ignition of d droplet array and opened the possibility of further research.

• Journal of the Korean Regional Science Association
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• v.34 no.2
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• pp.21-34
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• 2018

The purpose of this study is to analyze the spatial-temporal proliferation of individual factories in the Seoul Metropolitan Area and to provide policy implications. The location of the factory is divided into individual locations and planned locations. In the case of individual locations, it takes a long time to establish factories. Also, due to high cost and regulation, the establishment of individual factories is not easy. However, since the establishment process is simple and the price of land is low, the establishment of individual factories has led to an increase in the number of individual factories. The problem of the undeveloped factories is that the lack of infrastructure such as the road and environmental pollution treatment facilities around the factory deteriorates the pleasant environment and the cityscape and deteriorates the health of the residents in the surrounding area. In this study, we analyzed the location of individual factories established in the Seoul metropolitan area from 2001 to 2016 by using ArcGIS Pro. The results of the analysis are as follows. First, individual location factories are formed around existing industrial complexes and industrial sites. The reason for this is considered to be the external effect that can be obtained from the surrounding area. Secondly, since the Seoul city's individual location factories are established in many residential areas, it shows the conflicting result of the mixture of residence and factory. Third, the Gyeonggi province's individual location factories have a high proportion of non-urban areas. This is because the Gyeonggi province's management area occupies a larger proportion than other areas in Gyeonggi province. This study analyzed the spatial - temporal spreading process of individual factories and the unfolding of individual factories in the metropolitan area, and it can provide policy implications to control the over development of individual factories in the future.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.37 no.8
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• pp.1-10
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• 2000

Performance analyses of hybrid DS-SFH spread-spectrum systems using coherent MSK and QPSK modulation techniques are considered over Rayleigh fading channel in the presence of multi-tone jamming. The BER equations for MSK and QPSK systems with non-diversity reception in the receiver are derived as the concept of average signal-to-noise power ratio E$\_$b//N$\_$0/ and jamming-to-signal power ratio JSR, and the performances is evaluated for various system parameters. The evaluation of performance is done between fading and nonfading system, and between MSK and QPSK system. Results show that the performances of two systems are similar in low JSR. However, MSK system outperforms QPSK system as JSR increases. Overall performances of two systems are a little improved as the DS spreading gain increases for the total spread-spectrum bandwidth fixed. The performance difference between fading system and nonfading system is similar in low E$\_$b//N$\_$0/, however, it becomes very largewith increase of E$\_$b//N$\_$0/..

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2015.10a
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• pp.977-980
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• 2015

Beacons have been noted in the core of the recent things Internet. It is also the technology is spreading most rapidly among the things Internet-related communication technologies. Beacon is a data communications technology that provides information that is customized to know the user's location. Using the BLE technology, to grasp the position of such people and goods. In addition to the non-contact method, since it is possible to communicate within the maximum 70m, it has attracted the interest than the NFC. Beacon, guidance for the current coupon, you can use as an advertising platform, such as the provision of product information, it has also been used in the indoor positioning service. Therefore, in this paper, we introduce about whether Case Study beacon is utilized how in the Internet of Things, were analyzed. Beacon exit the smart phone, the date to be used in conjunction with a wearable device, such as Google glasses and smart watch was not far away. Future it is expected or beacons are used everywhere to be expanded.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.6 no.4
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• pp.413-420
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• 1994

Dynamics of the river plume is a very complicated non-linear problem with the free boundary changing in time and space. Mixing with the ambient water through the boundary makes the problem more complicated. In this paper we reduced 3-dimensional problem into 1-dimensional one by using the integral analysis method. Basic equations have been integrated over the lateral and vertical variations. For these integrations we adopted the well-established assumption that the flow-axis component of plume velocity and the density difference of the plume with the ambient water have Gaussian distributions in directions which are perpendicular to the flow-axis of the plume. We also used the result of our previous study on the lateral spreading velocity of the plume derived under the same assumption. And entrainment was included as a mixing process. The resultant 1-dimensional equations were solved by Runge-Kutta numerical method. Consequently, comparatively easy method of numerical analysis is presented for the 3-dimensional river plume. The method can also be used for the analysis of the thermal plume of cooling water of power plants.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.47 no.9
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• pp.649-657
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• 2019

Hydrazine, which is used as a representative monopropellant, is an extremely poisonous substance and has a disadvantage that it is harmful to the human body and is very difficult to handle. In recent years, research on the development of non-toxic and environmentally friendly propellants has attracted much attention. Ammonium dinitramide(ADN) based propellant developed by Swedish Space Corporation has superior performance to hydrazine and has been commercialized through performance verification in space environment. On the other hand, the exhaust gas from a thruster nozzle collides with a satellite while it is spreading in the vacuum space, thermal load and surface contamination may occur and may reduce the performance and lifetime of the satellite. However, a study on the effect of the exhaust gas of the green propellant thruster on the satellite has not been conducted in earnest yet. Therefore, the exhaust gas behavior in space was analyzed in this study for the ADN based green monopropellant using Navier-Stokes equations and the DSMC method. As a result, it can be expected to be used as design validation data in the development of satellite when using the ADN based green monopropellant.

• Clean Technology
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• v.27 no.2
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• pp.124-131
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• 2021

As declarations of carbon neutrality are spreading throughout the world, much research is being conducted on biodegradable polymers. In this study, nanocellulose, which comprises the largest amount of natural polymer currently available in the world, was proposed as a substitute for non-biodegradable polymers. We chose to modify the surface functional group of crystalline nanocellulose using glycidoxypropyl trimethoxysilane (GPTMS), which is a silane coupling agent, and the product was then used to form a film with low density polyethylene (LDPE). We then conducted measurements using a Fourier transform infrared spectrophotometer (FT-IR) in addition to measuring hydrophilic/lipophilicity of the surface functional group modification of crystalline nitrocellulose as well as that of a polymer composite using the hybrid nanocellulose (H-NC). For compatibility with petroleum-based polymers, the best tensile strength and transparency was found when the H-NC was reacted at pH 14 and 1 wt% compared with LDPE. From the test results, we found that it is possible to modify the surface functional groups of nanocellulose using a silane coupling agent. In addition, the high compatibility of nanocellulose with petroleum-based polymers is expected to help in reaching carbon neutrality by reducing the use of fossil fuels.

• Korean Journal of Environmental Biology
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• v.41 no.2
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• pp.101-108
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• 2023

Recently, in relation to climate change, many studies have been conducted to predict the potential habitat area and distribution range of tilapia and the suitability of habitat for each species. Most tilapia are tropical fish that cannot survive at water temperatures below 10 to 12℃, although some tilapia can survive at 6 to 8℃. This study predicted habitable areas and the possibility of spreading of habitat ranges of tilapia (Oreochromis niloticus and Oreochromis aureus) known to inhabit domestic streams. Due to climate change, it was found that habitats in the Geum River, Mangyeong River, Dongjin River, Seomjin River, Taehwa River, Hyeongsan River, and the flowing in East Sea were possible by 2050. In addition, it was confirmed that tilapia could inhabit the preferred lentic ecosystem such as Tamjin Lake, Naju Lake, Juam Lake, Sangsa Lake, Jinyang Lake, Junam Reservoir, and Hoedong Reservoir. In particular, in the case of tilapia, which lives in tributaries of the Geumho River, Dalseo Stream, and the Nakdong River, its range of habitat is expected to expand to the middle and lower of the Nakdong River system. Therefore, it is judged that it is necessary to prepare physical and institutional management measures to prevent the spread of the local population where tilapia currently inhabits and to prevent introduction to new habitats.

• Journal of Animal Science and Technology
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• v.65 no.1
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• pp.244-257
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• 2023

The study aimed to investigate the effect of low-frequency oscillations on the cow udder, milk parameters, and animal welfare during the automated milking process. The study's objective was to investigate the impact of low-frequency oscillations on the udder and teats' blood circulation by creating a mathematical model of mammary glands, using milkers and vibrators to analyze the theoretical dynamics of oscillations. The mechanical vibration device developed and tested in the study was mounted on a DeLaval automatic milking machine, which excited the udder with low-frequency oscillations, allowing the analysis of input parameters (temperature, oscillation amplitude) and using feedback data, changing the device parameters such as vibration frequency and duration. The experimental study was performed using an artificial cow's udder model with and without milk and a DeLaval milking machine, exciting the model with low-frequency harmonic oscillations (frequency range 15-60 Hz, vibration amplitude 2-5 mm). The investigation in vitro applying low-frequency of the vibration system's first-order frequencies in lateral (X) direction showed the low-frequency values of 23.5-26.5 Hz (effective frequency of the simulation analysis was 25.0 Hz). The tested values of the first-order frequency of the vibration system in the vertical (Y) direction were 37.5-41.5 Hz (effective frequency of the simulation analysis was 41.0 Hz), with higher amplitude and lower vibration damping. During in vivo experiments, while milking, the vibrator was inducing mechanical milking-similar vibrations in the udder. The vibrations were spreading to the entire udder and caused physiotherapeutic effects such as activated physiological processes and increased udder base temperature by 0.57℃ (p < 0.001), thus increasing blood flow in the udder. Used low-frequency vibrations did not significantly affect milk yield, milk composition, milk quality indicators, and animal welfare. The investigation results showed that applying low-frequency vibration on a cow udder during automatic milking is a non-invasive, efficient method to stimulate blood circulation in the udder and improve teat and udder health without changing milk quality and production. Further studies will be carried out in the following research phase on clinical and subclinical mastitis cows.