• 품질경영학회지
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• 제49권1호
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• pp.31-45
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• 2021

Purpose: A noncentral composite design method is to be developed to explore farther region for the first factorial design. A general guideline for sequential experimentation is provided. Methods: (1) A non-overlapping noncentral composite design (NNCD) is developed, in which the second factorial design shares one design point that indicates the best response value in the first factorial design. (2) Four composite designs are compared in terms of the four design evaluation criteria, which are D-, A, G, and I-optimality. (3) A follow-up design strategy is suggested based on the interaction effect, direction of improvement, number of factors. Results: (1) NNCD and model building method are presented, which is useful for exploring farther region from first factorial design block. (2) The performances of the four composite designs are compared. (3) A follow-up design strategy is suggested. Conclusion: (1) NNCD will be useful to explore farther region for the first factorial design. (2) A follow-up design strategy can be beneficial to the experimental practitioners for product and process design and improvement.

• 한국생산제조학회지
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• 제24권2호
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• pp.211-216
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• 2015

Recently, because of the growth in the leisure industry and interest in health, the demand for bicycles has increased. In this research, considering the vertical load on a bike frame under static state conditions, the deflection and mass of the bike frame were minimized by satisfying the service condition and performing optimization. The thickness of the bicycle-frame tube was set to a design variable, and its sensitivity was confirmed by an analysis of means (ANOM). To optimize the solution, a response-surface-method (RSM) model was constructed using D-Optimal and central composite design(CCD). The optimization was performed using a non-dominant sorting genetic algorithm (NSGA-II), and the optimal solution was verified by finite-element analysis.

• 한국생산제조학회지
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• 제24권2호
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• pp.192-197
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• 2015

In many fields, the importance of reducing weight is increasing. A product should be designed such that it is profitable, by lowering costs and exhibiting better performance than other similar products. In this study, the mass and deflection of steel structures have to be reduced as objective functions under constraint conditions. To reduce computational analysis time, central composite design(CCD) and D-Optimal are used in design of experiments(DOE). The accuracy of approximate models is evaluated using the $R^2$ value. In this study, the objective functions are multiple, so the non-dominant sorting genetic algorithm(NSGA-II), which is highly efficient, is used for such a problem. In order to verify the validity of Pareto solutions, CAE results and Pareto solutions are compared.

• Archives of Pharmacal Research
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• 제27권7호
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• pp.797-805
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• 2004

LPD vectors are non-viral vehicles for gene delivery comprised of polycation-condensed plasmid DNA and liposomes. Here, we described a novel anionic LPD formulation containing protamine-DNA complexes and pH sensitive liposomes composed of DOPE and cholesteryl hemisuccinate (Chems). Central composite design (CCD) was employed to optimize stable LPD formulation with small particle size. A three factor, five-level CCD design was used for the optimization procedure, with the weight ratio of protamine/DNA ($X_1$), the weight ratio of Chems/DNA ($X_2$) and the molar ratio of Chems/DOPE in the anionic liposomes ($X_3$) as the independent variables. LPD size ($Y_1$) and LPD protection efficiency against nuclease ($Y_2$) were response variables. Zeta potential determination was utilized to define the experimental design region. Based on experimental design, responses for the 15 formulations were obtained. Mathematical equations and response surface plots were used to relate the dependent and independent variables. The mathematical model predicted optimized $X_1-X_3$ levels that achieve the desired particle size and the protection efficiency against nuclease. According to these levels, an optimized LPD formulation was prepared, resulting in a particle size of 185.3 nm and protection efficiency of 80.22％.

• 한국생산제조학회지
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• 제24권3호
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• pp.302-307
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• 2015

The automobile is an important means of transportation. For this reason, the automotive wheel is also an important component in the automotive industry because it acts as a load support and is closely related to safety. Thus, the wheel design is a very important safety aspect. In this paper, an optimal design for minimizing automotive wheel stress and increasing wheel safety is described. To study the optimal design, a central composite design (CCD) and D-optimal design theory are applied, and the approximate function using the response surface method (RSM) is generated. The optimal solutions using the non-dominant sorting genetic algorithm (NSGA-II) are then derived. Comparing CCD and D-optimal solution accuracy and verified the CCD can deduce more accuracy optimal solutions.

• Journal of Mechanical Science and Technology
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• 제16권5호
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• pp.599-608
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• 2002

Finite element analysis for the stress intensity factor (SIF) at the skin/stiffener structure with inclined central crack repaired by composite stiffened panels is developed. A numerical investigation was conducted to characterize the fracture behavior and crack growth behavior at the inclined crack. In order to investigate the crack growth direction, maximum tangential stress (MTS) criterion are used. Also, this paper is to study the performance of the effective bonded composite patch repair of a plate containing an inclined central through-crack. The main objective of this research is the validation of the inclined crack patching design. In this paper, the reduction of stress intensity factors at the crack-tip and prediction of crack growth direction are determined to evaluate the effects of various non-dimensional design parameter including; composite patch thickness and stiffener distance. We report the results of finite element analysis on the stiffener locations and crack slant angles and discuss them in this paper. The research on cracked structure subjected to mixed mode loading is accomplished and concludes that more work using a different approaches is necessary. The authors hope the present study will aid those who are responsible for the repair of damaged aircraft structures and also provide general repair guidelines.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2004년도 추계학술대회
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• pp.510-515
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• 2004

A proton exchange membrane fuel cells(PEMFC) operate at low temperature, allowing for faster startups and immediate response to change in the demand for power, and also deliver high power density. To maximize economical efficiency in PEMPC, it is necessary to the optimization. Response surface method(RSM) has non-gradient and fast convergency characteristics. Sampling points are extracted by design of experiments using Central Composite Method. In this paper, it is shown that the optimization is required for the design study of the PEMFC.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2003년도 추계학술대회
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• pp.1430-1435
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• 2003

Satellite upper platform is optimized by response surface method which has non-gradient, semi-glogal, discrete and fast convergency characteristics. Sampling points are extracted by design of experiments using Central Composite Method and Factorial Design. Also response surface is generated by the various regression functions. Structure analysis is execuated with regard for static and dynamic environment in launching stage. As a result response surface method is superior to other optimization method with respect to optimum value and cost of computation time. Also a confidence is varified in the various regression models.

• 한국정밀공학회지
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• 제32권9호
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• pp.815-824
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• 2015

In this study, we conducted the approximate multi-objective optimization of gap sizes of pressurized-water reactor (PWR) annular fuels. To determine the contacting tendency of the inner-outer gaps between the annular fuel pellets and cladding, thermoelastic-plastic-creep (TEPC)analysis of PWR annular fuels was performed, using in-house FE code. For the efficient heat transfer at certain levels of stress, we investigated the tensile, compressive hoop stress and temperature, and optimized the gap sizes using the non-dominant sorting genetic algorithm (NSGA-II). For this, response surface models of objective and constraint functions were generated, using central composite (CCD) and D-optimal design. The accuracy of approximate models was evaluated through $R^2$ value. The obtained optimal solutions by NSGA-II were verified through the TEPC analysis, and we compared the obtained optimum solutions and generated errors from the CCD and D-optimal design. We observed that optimum solutions differ, according to design of experiments (DOE) method.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2001년도 춘계학술대회논문집A
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• pp.292-297
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• 2001

Composite patch repair of cracked aircraft structures has been accepted as one of improving fatigue life and attaining better structural integrity. Analysis for the stress intensity factor at the skin/stiffener structure with inclined central crack repaired by composite stiffened panels are developed. A numerical investigation was conducted to characterize the fracture behavior and crack growth behavior. In order to investigate the crack growth direction, maximum tangential stress(MTS) criteria is used. The main objective of this research is the validation of the inclined crack patching design. In this paper, the reduction of stress intensity factors at the crack-tip and prediction of crack growth direction are determined to evaluate the effects of various non-dimensional design parameter including; composite patch thickness and stiffener distance. The research on cracked structure subjected to mixed mode loading is accomplished and it is evident that more work using different approaches is necessary.