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Studies on the Non-surgical Embryo Collection by Shortening of Uterine Horn in Swine II. Effect of Uterus Shortening on the Estrus Cycle and the Level of Progesterone and Prostaglandin Fao in Serum (돼지에 있어서 자궁각 단축술에 의한 수정란의 비외과적 채란에 관한 연구 II. 자궁각 단축이 발정주기 및 혈청 중 호르몬 수준변화에 미치는 영향)

  • 김희석
    • Journal of Veterinary Clinics
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    • v.15 no.1
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    • pp.94-99
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    • 1998
  • This study was carried out to determine the effects of uterus shortening on the duration required for estrus, the number of ovulation and the level of serum progesterone and prostaglandin $F_{2}{\alpha} (PGF_{2}{\alpha} $). The duration required for estrus after the surgical shortening of uterine horns and the interval between the following estrus was not affected by the surgical treatment but affected by luteal and follicular phase. The number of ovulations were increased by induction of superovulation to gilts with shortened uterine horns compared to the control. Serum progesterone concentration during the luteal phase was higher than that during the follicular phase with no difference between the control and me horns than that of the control. Findings of this study indicate that luteal formation and regressions and estrus cycle were normal when the unconnected parts of uterine horns were left in abdominal cavity. Therefore surgical shortening of uterine horns of sows helps embryo collections by non-surgical methods.

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The Non-Canonical Effect of N-Acetyl-D-Glucosamine Kinase on the Formation of Neuronal Dendrites

  • Lee, HyunSook;Cho, Sun-Jung;Moon, Il Soo
    • Molecules and Cells
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    • v.37 no.3
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    • pp.248-256
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    • 2014
  • N-acetylglucosamine kinase (GlcNAc kinase or NAGK; EC 2.7.1.59) is a N-acetylhexosamine kinase that belong to the sugar kinase/heat shock protein 70/actin superfamily. In this study, we investigated both the expression and function of NAGK in neurons. Immunohistochemistry of rat brain sections showed that NAGK was expressed at high levels in neurons but at low levels in astrocytes. Immunocytochemistry of rat hippocampal dissociate cultures confirmed these findings and showed that NAGK was also expressed at low levels in oligodendrocytes. Furthermore, several NAGK clusters were observed in the nucleoplasm of both neuron and glia. The overexpression of EGFP- or RFP (DsRed2)-tagged NAGK in rat hippocampal neurons (DIV 5-9) increased the complexity of dendritic architecture by increasing the numbers of primary dendrites and dendritic branches. In contrast, knockdown of NAGK by shRNA resulted in dendrite degeneration, and this was prevented by the co-expression of RFP-tagged NAGK. These results suggest that the upregulation of dendritic complexity is a non-canonical function of NAGK.

Corrosion resistance of a carbon-steel surface modified by three-dimensional ion implantation and electric arc.

  • Valbuena-Nino, E.D.;Gil, L.;Hernandez, L.;Sanabria, F.
    • Advances in materials Research
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    • v.9 no.1
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    • pp.1-14
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    • 2020
  • The hybrid method of three-dimensional ion implantation and electric arc is presented as a novel plasma-ion technique that allows by means of high voltage pulsed and electric arc discharges, the bombardment of non-metallic and metallic ions then implanting upon the surface of a solid surface, especially out of metallic nature. In this study AISI/SAE 4140 samples, a tool type steel broadly used in the industry due to its acceptable physicochemical properties, were metallographically prepared then surface modified by implanting titanium and simultaneously titanium and nitrogen particles during 5 min and 10 min. The effect of the ion implantation technique over the substrate surface was analysed by characterization and electrochemical techniques. From the results, the formation of Ti micro-droplets upon the surface after the implantation treatment were observed by micrographs obtained by scanning electron microscopy. The presence of doping particles on the implanted substrates were detected by elemental analysis. The linear polarization resistance, potentiodynamic polarization and total porosity analysis demonstrated that the samples whose implantation treatment with Ti ions for 10 min, offer a better protection against the corrosion compared with non-implanted substrates and implanted at the different conditions in this study.

Stoichiometry and Stability of Complexes Formed between 18-Crown-6 as well as Digenzo-18-Crown-6 Ligands and a Few Metal Ions in Some Non-aqueous Binary Systems Using Square Wave Polarography

  • A. Nezhadali, Gh. Rounaghi;M. Chamasaz
    • Bulletin of the Korean Chemical Society
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    • v.21 no.7
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    • pp.685-689
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    • 2000
  • The complexation reaction between Pb2+,TI and Cd2+ions and macrocyclic ligands, 18-crown-6 ( 18C6) and dibenzo- 18-crown-6 (DB 18C6), was studied in dimethylsulfoxide (DMSO)-nitromethane (NM) and dimethyl-formamide (DMF)-nitromethane binary system s by square wave polarography (SWP) technique. The stoichiometry and stability of the complexes were determined by monitoring the shifts in half-waves or peak potentials of the polarographic waves of metal ions against the Iigand concentration. In most cases, the stability constants of complexes increase with increasing amounts of the nitromethane in mixed binary solvents used in this study. The complexes formed between 18C6 and DB18C6 and these metal cations in all cases had a stoichiometry of 1 : 1. The results obtained show that there is an inverse relationship between the formation constant of complexes and the donor number of solvents based on a Gatmann donocity scale and the stability constants show a high sensitivity to the composition of the mixed solvent systems. A linear behavior was observed for variation of log Kf of I8C6 complexes vs the composition of the mixed solvent systems in NM/DMSO and NM/DMF,but a non-linear behavior was observed in the case of DB 18C6 complexes in these binary systems. In most of the systems investigated, the Pb2+ cation forms a more stable complex with the 18C6 than other two cations and the order of selectivity of this Iigand for cations is: Pb2+ > TI+,Cd2+.

Fabrication and Characteristics of Non-Solvent Silica-Acryl Monomer Hybrid Sol for Optical Device (광학용 무용제 실리카-아크릴 모노머 하이브리드 졸 기반의 코팅액 제조 및 특성 평가)

  • Kang, Woo Kyu;Jang, Gun Eik
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.32 no.3
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    • pp.246-251
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    • 2019
  • A solvent free, highly concentrated silica-acryl monomer hybrid sol was synthesized using aqueous colloidal silica as a precursor. The effects of the silica particle size, type of surface treatment agent employed, and silica content on the formation of the hybrid sol were systematically studied. The optical and physical properties of the coating solution prepared using the hybrid sol were also characterized. The viscosity of the hybrid sol tended to decrease as the particle size of the silica and the molecular weight of the surface treatment agent increased. The PET substrate coated with MPTMS-Mix (mixture, 70 wt%) solution showed the highest surface hardness (6 H) and low surface roughness ($Ra=0.044{\mu}m$), which could be attributed to an increase in packing density caused by the infiltration of small particles into the pores formed between larger particles.

Edge-Cracking Behavior of CoCrFeMnNi High-Entropy Alloy During Hot Rolling

  • Won, Jong Woo;Kang, Minju;Kwon, Heoun-Jun;Lim, Ka Ram;Seo, Seong Moon;Na, Young Sang
    • Metals and materials international
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    • v.24 no.6
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    • pp.1432-1437
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    • 2018
  • This work investigated edge-cracking behavior of equiatomic CoCrFeMnNi high-entropy alloy during hot rolling at rolling temperatures $500{\leq}T_R{\leq}1000^{\circ}C$. Edge cracks did not form in the material rolled at $500^{\circ}C$, but widened and deepened into the inside of plate as $T_R$ increased from $500^{\circ}C$. Edge cracks were most severe in the material rolled at $1000^{\circ}C$. Mn-Cr-O type non-metallic inclusion and oxidation were identified as major factors that caused edge cracking. The inclusions near edge region acted as preferential sites for crack formation. Connection between inclusion cracks and surface cracks induced edge cracking. Rolling at $T_R{\geq}600^{\circ}C$ generated distinct inclusion cracks whereas they were not serious at $T_R=500^{\circ}C$, so noticeable edge cracks formed at $T_R{\geq}600^{\circ}C$. At $T_R=1000^{\circ}C$, significant oxidation occurred at the crack surface. This accelerated edge crack penetration by embrittling the crack tip, so severe edge cracking occurred at $T_R=1000^{\circ}C$.

Antioxidation and anti-inflammatory effects of gamma-irradiated silk sericin and fibroin in H2O2-induced HaCaT Cell

  • Ji-Hye Choi;Sangmin Lee;Hye-Ju Han;Jungkee Kwon
    • The Korean Journal of Physiology and Pharmacology
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    • v.27 no.1
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    • pp.105-112
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    • 2023
  • Oxidative stress in skin cells can induce the formation of reactive oxygen species (ROS), which are critical for pathogenic processes such as immunosuppression, inflammation, and skin aging. In this study, we confirmed improvements from gamma-irradiated silk sericin (I-sericin) and gamma-irradiated silk fibroin (I-fibroin) to skin cells damaged by oxidative stress. We found that I-sericin and I-fibroin effectively attenuated oxidative stress-induced ROS generation and decreased oxidative stress-induced inflammatory factors COX-2, iNOS, tumor necrosis factor-α, and interleukin-1β compared to the use of non-irradiated sericin or fibroin. I-sericin and Ifibroin effects were balanced by competition with skin regenerative protein factors reacting to oxidative stress. Taken together, our results indicated that, compared to non-irradiated sericin or fibroin, I-sericin, and I-fibroin had anti-oxidation and antiinflammation activity and protective effects against skin cell damage from oxidative stress. Therefore, gamma-irradiation may be useful in the development of cosmetics to maintain skin health.

Granuloma Formation, a Rare Complication after PDO Threads Lifting, and Adjuvant Treatment Using Dual-Frequency Ultrasound (LDM®-MED)

  • Hong, Seok Won;Park, Eun Soo
    • Medical Lasers
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    • v.8 no.1
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    • pp.35-38
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    • 2019
  • Thread-lifting is a minimally invasive procedure that shows good results and fewer complications as compared with those results and complications of standard surgery. Many procedures and techniques have been developed to create a younger appearance of facial/neck skin for aging people, and the demand for an improved aesthetic appearance is increasing. Since the incidence of side effects is much less than that of non-absorbable threads, which can lead to complications such as foreign body reactions, polydioxanone (PDO) threads are predominantly used for face lift procedures. A 66-year-old woman presented to our clinic with inflamed palpable masses. She had undergone a face lift with absorbable threads in our clinic 5 months previously. Excisional biopsy was performed with the patient under local anesthesia. During the operation, any threads were not detected and there was both fibrotic scar tissue and granulomatous tissue. For effectively promoting healing and managing the scars, treatment with LDM®-MED was performed on the day after surgery. The treatment was performed according to the author's protocol. Although foreign body granuloma as a complication after using non-absorbable thread types have been previously reported, it is relatively rare to find this type of complication after using absorbable thread. In this report, we present a case in which a 66-year-old female with foreign body granuloma after undergoing a face lift using absorbable threads was treated with the application of dual-frequency ultrasound, which promoted wound healing.

Analyses of International Standard Problem ISP-47 TOSQAN experiment with containmentFOAM

  • Myeong-Seon Chae;Stephan Kelm;Domenico Paladino
    • Nuclear Engineering and Technology
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    • v.56 no.2
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    • pp.611-623
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    • 2024
  • The ISP-47 TOSQAN experiment was analyzed with containmentFOAM which is an open-source CFD code based on OpenFOAM. The containment phenomena taking place during the experiment are gas mixing, stratification and wall condensation in a mixture composed of steam and non-condensable gas. The k-ω SST turbulence model was adopted with buoyancy turbulence models. The wall condensation model used is based on the diffusion layer approach. We have simulated the full TOSQAN experiment which had a duration 20000 s. Sensitivity studies were conducted for the buoyancy turbulence models with SGDH and GGDH and there were not significant differences. All the main features of the experiments namely pressure history, temperature, velocity and gas species evolution were well predicted by containemntFOAM. The simulation results confirmed the formation of two large flow stream circulations and a mixing zone resulting by the combined effects of the condensation flow and natural convection flow. It was found that the natural convection in lower region of the vessel devotes to maintain two large circulations and to be varied the height of the mixing zone as result of sensitivity analysis of non-condensing wall temperature. The computational results obtained with the 2D mesh grid approach were comparable to the experimental results.

Effect of high amylose corn starch/dextrin on quality of non-fried instant noodles (고아밀로스 옥수수전분/덱스트린의 첨가가 건면의 품질에 미치는 영향)

  • You, Jae Geun;Lee, Ju Hun;Park, Eun Young
    • Korean Journal of Food Science and Technology
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    • v.52 no.6
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    • pp.655-660
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    • 2020
  • High amylose corn starch and dextrin (acid-treated at 30, 40 and 50℃ denominated as Dextrin30, Dextrin40 and Dextrin50) were added to non-fried instant noodles. X-ray diffraction pattern, water absorption, cooking loss, microstructure, and textural properties of non-fried instant noodles were investigated. The addition of high amylose corn starch/dextrin induced a slight peak intensity at 20o in the X-ray pattern indicating the insignificant formation of amylose-lipid complex. Non-fried instant noodles including high amylose corn starch/dextrin showed lower water absorption than the control. Dense microstructure in transverse section of noodles was observed in non-fried instant noodles including high amylose corn starch/dextrin except Dextrin50. Also, the addition of high amylose corn starch/dextrin induced low tensile strength, high firmness, and high stickiness. However, non-fried instant noodles containing Dextrin50 showed a loose microstructure and high cooking loss (3.98%), which might be associated with the textural properties such as the lowest tensile strength (0.17 N), lowest increase in firmness (46.77 N) and highest stickiness (18.43 N).