• Radiation Oncology Journal
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• 제13권2호
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• pp.129-142
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• 1995

Purpose: Traditionally the patients with early stage non-Hodgkin's lymphoma of the head and neck was treated with radiotherapy. But the results were not satisfactory due to distant relapse. Although combined treatment with radiotherapy and chemotherapy was tried with some improved results and chemotherapy alone was also tried in recent years, the choice of treatment for the patients with early stage non-Hodgkin's lymphoma of the head and neck has not been defined Therefore, in order to determine the optimum treatment method, we analysed retrospectively the outcomes of the patients with Ann Arbor stage I and II non-Hodgkin's lymphoma localized to the head and neck who were treated at Severance Hospital. Materials and Methods: 159 patients with stage I and II non-Hodgkin's lymphoma localized to the head and neck were treated at our hospital from January, 1979 to December, 1992. Of these patients, 114 patients whose primary sites were Waldeyer's ring or nodal region, and received prescribed radiation dose and/or more than 2 cycles of chemotherapy. were selected to analyze the outcomes according to the treatment methods ( radiotherapy alone, chemotherapy alone. and combined treatment with radiotherapy and chemotherapy ). Results: Five year overall actuarial survival of the patients whose Primary site was Waldeyer's ring was $62.5\%.$ and that of the Patients whose primary site was nodal region was $53.8\%$ There was no statistically significant difference between survivals of both groups. Initial response rate to radiotherapy. chemotherapy, and combined treatment was $92\%,\;83\%,\;94\%$ respectively, and 5 year relapse free survival was $49.9\%,\;52.4\%,\;58.5\%$ respectively ( statistically not significant ). In the patients with stage I. 3 year relapse free survival of chemotherapy alone group was $75\%$ and superior to other treatment groups. In the Patients with stage II, combined treatment group revealed the best result with $60.1\%$ of 3 year relapse free survival. The effect of sequential schedule of each treatment method in the Patients who were treated by combined modality was analyzed and the sequence of primary chemotherapy + radiotherapy + maintenance chemotherapy showed the best result ( 3 year relapse free survival was $79.1\%).$ There was no significant survival difference between BACOP regimen and CHOP regimen. Response to treatment was only one significant (p(0.005) prognostic factor on univariate analysis and age and mass size was marginally significant ( p(0.1). On multivariate analysis, age (p=0.026) and mass size (p=0.013) were significant prognostic factor for the relapse free survival. Conclusion: In summary, the patients who have non-Hodgkin's lymphoma of the head and neck with stage I and mass size smaller than 10 cm, can be treated by chemotherapy alone, but remainder should be treated by combined treatment method and the best combination schedule was the sequence of initial chemotherapy followed by radiotherapy and maintenance chemotherapy.

• 한국전산유체공학회지
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• 제15권2호
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• pp.28-34
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• 2010

Conductive and radiative thermal model configurations of an imager of a geostationary satellite are presented. A two-plane method is introduced for three dimensional conductive coupling which is not able to be treated by thin shell plate thermal modeling technique. Especially the two-plane method is applied to massive matters and PIP(Payload Interface Plate) in the imager model. Some massive matters in the thermal model are modified by adequate correction factors or equivalent thickness in order to obtain the numerical results of thermal modeling to be consistent with the analytic model. More detailed nodal breakdown is specially employed to the object which has the rapid temperature gradient expected by a rule of thumb. This detailed thermal model of the imager is supposed to be used for analyses and test predictions, and be correlated with the thermal vacuum test results before final in-flight predictions.

• 자원환경지질
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• 제19권4호
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• pp.283-292
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• 1986

3각형 및 4각형 요소를 사용한 유한요소법으로 임의의 2차원 비저항 구조에서 점전류원에 대한 전위분포를 구하였다. 이 모델링기술은 종래의 차분법보다 지하의 이상물질이나 지표의 지형을 모델화할 때 보다 더 유연할 뿐만 아니라 보다 더 정확한 수치해를 준다. 또한 이 방법은 해의 정확도에 별 영향없이 격자점을 줄일 수 있기 때문에 계산시간이나 기억용량면에서 경제적이다. 본 논문에서는 이러한 특징을 보여줄 몇 가지 모델에 대한 계산 결과를 소개한다.

• International Journal of Aeronautical and Space Sciences
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• 제18권4호
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• pp.601-613
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• 2017

An adjoint-based error estimation and mesh adaptation study is conducted for two-dimensional viscous flows on unstructured hybrid meshes. The error in an integral output functional of interest is estimated by a dot product of the residual vector and adjoint variable vector. Regions for the mesh to be adapted are selected based on the amount of local error at each nodal point. Triangular cells in the adaptive regions are refined by regular refinement, and quadrangular cells near viscous walls are bisected accordingly. The present procedure is applied to single-element airfoils such as the RAE2822 at a transonic regime and a diamond-shaped airfoil at a supersonic regime. Then the 30P30N multi-element airfoil at a low subsonic regime with a high incidence angle (${\alpha}=21deg.$) is analyzed. The same level of prediction accuracy for lift and drag is achieved with much less mesh points than the uniform mesh refinement approach. The detailed procedure of the adjoint-based mesh refinement for the multi-element airfoil case show that the basic flow features around the airfoil should be resolved so that the adjoint method can accurately estimate an output error.

• Steel and Composite Structures
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• 제22권2호
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• pp.301-321
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• 2016

The objective of this paper is to investigate buckling behavior of composite laminated cylinders by using semi-analytical finite strip method. The shell is subjected to deformation-dependent loads which remain normal to the shell middle surface throughout the deformation process. The load stiffness matrix, which is responsible for variation of load direction, is also throughout the deformation process. The shell is divided into several closed strips with alignment of their nodal lines in the circumferential direction. The governing equations are derived based on the first-order shear deformation theory with Sanders-type of kinematic nonlinearity. Displacements and rotations of the shell middle surface are approximated by combining polynomial functions in the meridional direction and truncated Fourier series along with an appropriate number of harmonic terms in the circumferential direction. The load stiffness matrix, which is responsible for variation of load direction, is also derived for each strip and after assembling, global load stiffness matrix of the shell is formed. The numerical illustrations concern the pressure stiffness effect on buckling pressure under various conditions. The results indicate that considering pressure stiffness causes buckling pressure reduction which in turn depends on various parameters such as geometry and lay-ups of the shell.

• 대한토목학회논문집
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• 제13권4호
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• pp.27-37
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• 1993

응력 및 변위제약 하에 뼈대구조물의 초소중량설계를 얻기 위한 효율적인 방법을 제안한다. 주문제작이 빈번히 이루어지는 공학설계의 응용을 위해 다음의 5가지 단면형상을 고려하였다.(rectangular형, frame형, tube형, channel형 그리고 I형). 최적화 과정의 효율성을 증진시키기 위해 구조응답량(절점력, 변위)을 단면성질에 대해 1차 Taylor급수 전개했고 반면에 단면치수를 설계변수로 고려하였다. 제안된 방법의 효율성과 신뢰성을 보이기 위해 수치예를 통해 다른 방법에 의한 결과와 비교하였다. 그 결과 구조해석의 수를 크게 감소시킬 수 있었으며 뼈대구조물의 최적화에 매우 효율적으로 적용될 수 있음을 알게 되었다.

• Nuclear Engineering and Technology
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• 제31권4호
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• pp.401-407
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• 1999

We have performed two experiments in the fast critical assembly BFS to measure the effective delayed neutron fraction $\beta$$_{eff}$ values and compared the results to validate the $\beta$$_{eff}$ computation code, BETA-K. Measurements of $\beta$$_{eff}$ were carried out in a metallic plutonium core and a metallic uranium core with Cf$^{252}$ source pseudo-reactivity method. Fission integrals and correction factors, which were used to obtain the experimental $\beta$$_{eff}$ values, were calculated by using the LMR core design computation code system of KAERI. BETA-K has been developed consistently with the hexagonal Nodal Expansion Method (NEM) and it used delayed neutron data of ENDF/B-VI. By comparing the computed $\beta$$_{eff}$ values with the measured ones, we found that the results from BETA-K agreed with the experimental values within the experimental error bound.ror bound.

• 한국통신학회논문지
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• 제12권3호
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• pp.267-275
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• 1987

회로망내에 존재하는 절점과 가지를 분할하여 몇 개의 부분회로망으로 나누고 분할절점에서의 전압 및 전류관계식으로부터 회로망방정식을 정식화하여 각 부분회로망 별로 독립적으로 처리함으로서 대형회로망을 효율적으로 해석할 수 있도록 하였다. 본 논문에서 제안한 분할회로망에 대한 방정식은 분할하기 전의 단일회로망에 대한 방정식과 비교할 때 절점의 순서만 재 배열한 결과가 되므로, 종래의 단일회로망에 대한 산법을 그대로 분할법에 적용할 수 있다. 또한, 어드미턴스행렬의 블록대각형구조를 이용한 병렬계산 알고리즘을 제시하였다.

• 한국해안해양공학회지
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• 제5권3호
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• pp.204-211
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• 1993

Laplace 방정식을 Green 공식으로 해석한 경계요소법을 이용하여 수치수조에서 비선형파를 재현하였다. 미지수는 유체영역의 경계에 설정한 각 절점에서의 속도포텐셜과 수면변위이며 이를 구하기 위하여 지배방정식과 자유수면 경계조건을 기본식으로 하는 연립 1차방정식을 구성하였다. 동력학적 자유수면 경계조건에서 속도의 제곱항을 고려하였으며 자유수면 경계에서 속도포텐셜의 연직변화를 고려하여 이의 시간미분을 계산하였다. 본 수치모델을 이용하여 고립파와 Stokes의 2차 파낭을 재현한 결과, 이론치와 매우 잘 일치함을 확인하였다.

• Structural Engineering and Mechanics
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• 제53권2호
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• pp.261-276
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• 2015

Structural damage and moving load identification are the two aspects of structural system identification. However, they universally coexist in the damaged structures subject to unknown moving load. This paper proposed a dynamic response sensitivity-based model updating method to simultaneously identify the structural damage and moving force. The moving force which is equivalent as the nodal force of the structure can be expressed as a series of orthogonal polynomial. Based on the system Markov parameters by the state space method, the dynamic response and the dynamic response derivatives with respect to the force parameters and elemental variations are analytically derived. Afterwards, the damage and force parameters are obtained by minimizing the difference between measured and analytical response in the sensitivity-based updating procedure. A numerical example for a simply supported beam under the moving load is employed to verify the accuracy of the proposed method.