• 제목/요약/키워드: Negative resistance

검색결과 1,055건 처리시간 0.025초

Prevalence of resistance to macrolide, lincosamide. streptogramin and ketolide antibiotics against Gram-positive bacteria in Korea

  • Lim, Jung-A;Yoon, Eung-Jeong;Kim, Sung-Hoon;Choi, Sung-Sook;Choi, Eung-Chil
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.127.1-127.1
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    • 2003
  • The purpose of this study is to investigate the prevalence of resistance to macrolide, lincosamide, streptogramin and ketolide antibiotics in Korea. The antibiotic susceptibility test was performed to the macrolide erythromycin, clarithromycin, azithromycin, josamycin, the lincosamide clindamycin, the streptogramin synercid and the ketolide ABT -773 against 337 clinical Staphylococcus aureus(SAU). Coagulase-negative Staphylococci (CNS) and Enterococci isolates exhibited an average percentage of 64%, 56%, and 81 % of resistance to erythromycin, respectively.

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현장타설말뚝의 잔류응력 분포에 관한 연구 (A Study on the Distribution of Residual Stress for Drilled Shaft)

  • 김원철;황영철;안창윤
    • 한국지반환경공학회 논문집
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    • 제6권1호
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    • pp.45-51
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    • 2005
  • 말뚝을 설계함에 있어 극한지지력을 산정하는 것만으로는 말뚝의 장기 거동에 있어서의 하중분포를 고려할 수 없으므로 재하시험시 변형률계나 응력계를 사용하여 말뚝의 하중 재하에 따른 주면저항(the shaft resistance)의 분포를 측정하고 있다. 그러나 대부분의 재하시험시 하중이 '0'일 때를 'zero time'으로 하여 계측기의 값을 읽는 'zero reading'을 가정함으로써 현장타설말뚝이나 항타말뚝의 시공시 발생된 잔류응력(the residual stress 또는 the residual load)을 무시하고 있다. 이러한 'zero reading'의 가정은 말뚝 시공시 발생하는 말뚝 하방향으로의 부주면마찰력인 잔류응력을 고려하지 않으므로 실제 말뚝주면의 하중분포와는 다른 결과를 보이게 된다. 본 연구에서는 현장에 시험시공된 현장타설말뚝에 대하여 정재하시험을 수행하였고, 말뚝 주면의 하중분포 측정시 변형률계를 사용하여 콘크리트 타설 직후부터 계측을 실시함으로써 말뚝 시공에 따른 잔류응력을 측정하였다. 그 결과, 잔류응력이 고려된 경우는 초기에 부의 응력상태를 보이나 하중이 재하됨에 따라 부주면마찰력이 극복되면서 양의 주면마찰력으로 전환됨을 알 수 있었으나, 'zero reading'의 경우는 양의 주면마찰력 만을 보였다.

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공기중에서 분리된 포도구균의 항생제 감수성 (Antibiotics Sensitivity to Isolated Staphylococcus sp. from the Air)

  • 김성광;박미경;정재규
    • 대한미생물학회지
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    • 제20권1호
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    • pp.13-23
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    • 1985
  • This investigation was performed to isolate and identify Staphylococcus sp. from air at the 25 sites in one hospital in Daegu. Drug sensitivity tests bacteriologically were also studied. The results are summarized as follows: 1. In gram staining of isolated colonies, the number of staphylococci strains was 959(70.2%) among 1367 collected in the morning, and 653(66.2%) among 987 collected in the afternoon. 2. The number of isolates was slightly higher in samples collected from the outpatient treatment rooms and wards in the main building than in samples from the other sites. 3. In biochemical tests of 1612 strains of isolates gram positive cocci, the number of coagulase positive strains was 584(36.2%) and coagulase negative 1028(63.8%). In experiments on growth on mannitol agar containing 7.5% NaCl and mannitol fermentation tests, the number of mannitol fermentation strains was 423(30.8%) and nonfermenter was 951(59.2%). 4. In antibiotic sensitivity tests of 746 identified strains of staphylococci, coagulase positive strains showed resistance in. higher portions to penicillin(89.7%), chloramphenicol(64.6%), gentamycin (52.1%) and tetracycline(45.2%), whereas in lower portions to kanamycin(39.2%) and apmicillin(33.1%). 5. Among coagulase negative and mannitol fermenting strains, higher portions showed resistance to chloramphenicol(76.5%), penicillin(69.8%) and ampicillin(63.6%), whereas lower portions showed resistance to kanamycin(48.8%), tetracycline(39.5%) and gentamycin(34.0%). 6. The number of strains showing multiple resistance to above 6 antibiotics were 15(52(19.8%) among coagulase positive and mannitol non-fermenter and 36(22.2%) among coagulase negative and mannitol fermenter.

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크로스-결합구조의 부성 미분 저항 회로를 이용한 페리티-시간 대칭 구조의 비접촉 센서 구동 회로에 대한 연구 (Non-Contact Sensing Method using PT Symmetric Circuit with Cross-Coupled NDR Circuits)

  • 홍종균
    • 한국산학기술학회논문지
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    • 제22권4호
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    • pp.10-16
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    • 2021
  • 본 연구에서는 신축성 인덕터를 이용한 센서 응용을 위한 상태 감지 회로로써 패리티-시간 대칭 구조를 고려한 모델을 제안하고자 한다. 신축성 인덕터를 이용한 센서 구동 회로로써 트랜지스터를 이용한 부성 미분 저항 회로를 적용하여 신축성 인덕터를 보다 효율적으로 활용할 수 있는 방법을 제안하고, 패리티-시간 대칭 구조의 결합 공진 회로에 대한 특성 분석을 통해 고전적 공진 회로에 비해 향상된 분해능을 갖는 모델을 설계하였다. 특히, 보다 실질적인 전산모의실험결과를 얻기 위해, 신축성 인덕터 모델의 경우에는 참고문헌의 실험결과를 참고하여 본 연구 모델에 적용하였다. 전산모사를 통해 본 연구에서 사용한 부성 미분 저항 회로를 통해 저항 성분 뿐만 아니라 위상 성분도 제어됨을 확인하였으며, 이러한 결과를 통해 신축성 인덕터의 특성 변화에 따른 회로의 불균형을 부성 미분 저항 회로를 이용하여 보완할 수 있음을 고찰하였다. 이러한 특성을 이용하여 패리티-시간 대칭 구조를 구현할 수 있었으며, 이에 대한 특성에 대하여 논의하였다. 특히, 본 연구에서 제안하는 패리티-시간 대칭 구조의 센서 구동 회로에 대한 주파수 특성의 결과로부터 기존의 고전적 공진 회로에 비해 Q-factor가 최대 20배까지 커질 수 있음을 확인하였다.

ANALYTICAL SIMULATION OF TRAVEL RESISTANCE OF THE RUBBER CRAWLER SYSTEM FOR FARM MACHINERY

  • Inaba, S.;Inoue, E.;Hashiguchi, K.;Matsuo, T.
    • 한국농업기계학회:학술대회논문집
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    • 한국농업기계학회 2000년도 THE THIRD INTERNATIONAL CONFERENCE ON AGRICULTURAL MACHINERY ENGINEERING. V.II
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    • pp.139-145
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    • 2000
  • The mechanism of the inner resistance in a rubber crawler system has been investigated to reduce the power requirement (Kitano et al. 1994). The rolling resistance of the track roller, which is one of the major inner resistances, was measured for seven different vertical loads. The rolling resistance changed periodically and could be classified into three types. In case of the vertical load less than 500N, the rolling resistance was almost constant. For the vertical load greater than 500N, the maximum value of the rolling resistance increased. Further more in case of the vertical load greater than 1200N, negative resistance appeared. Analytical simulation of the travel resistance based on experimental results and static equilibrium equations derived from three-dimension mechanical model for the rubber crawler system. It was found that the simulation method was carried out to evaluate the travel resistance occurred by the rolling resistance of the track roller. The rolling resistance for each track roller arrangement and effects of the lug phase in the right and left rubber crawler could be estimated quantitatively.

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Pt 나노입자가 분산된 SiO2 박막의 저항-정전용량 관계 (Relation between Resistance and Capacitance in Atomically Dispersed Pt-SiO2 Thin Films for Multilevel Resistance Switching Memory)

  • 최병준
    • 한국재료학회지
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    • 제25권9호
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    • pp.429-434
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    • 2015
  • Resistance switching memory cells were fabricated using atomically dispersed Pt-$SiO_2$ thin film prepared via RF co-sputtering. The memory cell can switch between a low-resistance-state and a high-resistance-state reversibly and reproducibly through applying alternate voltage polarities. Percolated conducting paths are the origin of the low-resistance-state, while trapping electrons in the negative U-center in the Pt-$SiO_2$ interface cause the high-resistance-state. Intermediate resistance-states are obtained through controlling the compliance current, which can be applied to multi-level operation for high memory density. It is found that the resistance value is related to the capacitance of the memory cell: a 265-fold increase in resistance induces a 2.68-fold increase in capacitance. The exponential growth model of the conducting paths can explain the quantitative relationship of resistance-capacitance. The model states that the conducting path generated in the early stage requires a larger area than that generated in the last stage, which results in a larger decrease in the capacitance.

개의 비루에서 분리한 원인균의 항생제 내성 (Antibiotic Resistance of Bacterial Isolates from Nasal Discharges of Dogs with Respiratory Diseases)

  • 김문선;정종태;강태영;윤영민;이주명;이두식;손원근
    • 한국임상수의학회지
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    • 제21권2호
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    • pp.133-139
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    • 2004
  • Bacterial pathogens were isolated from 36 dogs with respiratory signs, that were submitted to Veterinary Clinics in Jeju, including Veterinary Medical Teaching Hospital in Cheju National University. Of 36 isolates, 16 (44.4%) bacterial pathogens were Gram-positive and 20 (55.6%) were Gram-negative. Gram-positive bacteria identified with API Staph were 12 S. intermedius (33.3%), 2 S. aureus (5.6%), 1 S. haemolyticum (2.8%), and 1 S. xylosus (2.8%). Gram-negative organisms identified with API 20E or API NE included 8 Bordetella bronchiseptica (22.2%), 6 Escherichia coli (16.7%), 4 Pasteurella spp. (11.1%), 1 Enterobacter intermedius (2.8%), and 1 Oligella ureolytica (2.8%). Both Staphylococcus spp. isolates and Gram-negative pathogens were resistant to one or more antibiotics, including ampicillin (AM), amoxicillin/clavulanic acid (AMC), chloramphenicol (C), cefazolin (CZ), erythromycin (E), gentamicin (GM), kanamycin (K), lincomycin (L), oxacillin (OX), trimethoprim/sulfamethoxazole (SXT), and tetracycline (TE). All Staphylococcus spp. were susceptible to AMC, OX and VA, while many isolates were highly resistant to L (87.5%), E (68.8%), P (62.5%), and AM (56.3%). Antibiotic-resistant patterns of staphylococcal isolates were shown ranges from single to 9-resistant patterns. Resistant rates to antibiotics of Gram-negative bacteria were usually higher than those of Staphylococcus spp. in this study. Most Gram-negative bacteria were highly resistant to L (90.0%), AM (85.0%), E (85.0%), P (85.0%), OX (80.0%), and CZ (75.0%). B. bronchiseptica isolates showed 5 to 8 antibiotics-resistant patterns and Pasteurella spp., 2 to 8-resistant patterns. In particular, all 6 E. coli isolates were resistant to more than 9 different kinds of antibiotics, including one strain resistant to all antibiotics tested.

Increases of Antibiotic Resistance in Excessive Use of Antibiotics in Smallholder Dairy Farms in Northern Thailand

  • Suriyasathaporn, W.;Chupia, V.;Sing-Lah, T.;Wongsawan, K.;Mektrirat, R.;Chaisri, W.
    • Asian-Australasian Journal of Animal Sciences
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    • 제25권9호
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    • pp.1322-1328
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    • 2012
  • Antibiotic resistance patterns of bacterial isolates from both quarter teat-tip swabs and their quarter milk samples were evaluated in smallholder dairy farms in northern Thailand with excessive use of antibiotics (HIGH) compared with normal use (NORM). Results from teat-tip swab samples showed that the percentage of Bacillus spp. resistance to overall antibiotics was significantly lower in the NORM group than that of the HIGH group, whereas, the resistance percentage of coagulase-negative staphylococci in the NORM group was higher than that of the HIGH one. The overall mastitis-causing bacteria isolated from milk samples were environmental streptococci (13.8%), coagulase-negative staphylococci (9.9%), Staphylococcus aureus (5.4%), and Corynebacterium bovis (4.5%). Both staphylococci and streptococci had significantly higher percentages of resistance to cloxacillin and oxacillin in the HIGH group when compared to the NORM one. An occurrence of vancomycin-resistant bacteria was also observed in the HIGH group. In conclusion, the smallholder dairy farms with excessive use of antibiotics had a higher probability of antibiotic-resistant pattern than the farms with normal use.

HDPE 가교 결합과 계면 접착력 변화에 따른 PTC 특성 연구 (Effects of Interfacial Adhesion and Chemical Crosslinking of HDPE Composite Systems on PTC Characteristics)

  • 김재철;이종훈;남재도
    • 폴리머
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    • 제27권4호
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    • pp.275-284
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    • 2003
  • 접착성이 없는 고밀도 폴리에틸렌 (HDPE)과 나노입자 카본블랙 복합체를 대상으로 전극과의 계면 접착 향상과 고분자 가교 특성에 따른 양온도 계수 (PTC) 특성을 연구하였다. 은페이스트를 전극으로 사용하였을 때에는, 전극과 HDPE의 접착 계면 저항으로 인하여 카본함량이 45 wt% 이상에서 1 $\Omega$ 이었으나, 덴드라이트 (dendrite)된 구리 전극의 경우 HDPE와 전극간의 넓은 면적 접촉에 의한 계면 저항이 0.2 $\Omega$ 이하였다. HDPE와 은페이스트의 계면 저항의 증가로 인하여 구리 박막을 사용하였을 때보다 전체적으로 저항이 높게 나타났다. HDPE와 나노입자 카본블랙 복합체는 온도가 증가하여 HDPE의 비캣연화온도까지는 저항이 일정하게 유지하다가, HDPE의 연화점에서 증가하기 시작하여 용융점에서 극대 값을 나타내는 전형적인 PTC특성을 보여주었다. 일반적으로 HDPE의 용융점을 넘어서면 음온도 계수 (NTC) 현상이 나타나는데, 가교결합을 시킨 HDPE의 경우는, 용융점 이상에서 NTC 현상이 나타나지 않고 저항이 일정하게 유지되거나 증가하는 경향이 나타났다. 구리 (copper) 전극과 고분자와의 계면 접촉 면적을 증가시키기 위하여 크롬 (chromium)을 덴드라이트시킨 전극을 사용하여 계면 접촉 저항을 감소시켰다.