• Title/Summary/Keyword: Natural substances

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Antimicrobial activity of vegetable and fruit juices on the scalp bacteria

  • Park, Young-Doo;Eum, Jin-Seong
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2007.10a
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    • pp.989-992
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    • 2007
  • Twenty bacterial strains were isolated and identified from human scalps. These strains were identified as 14 Bacillus megaterium, 1 Bacillus subtilis, 3 Staphylococcus aureus and 2 Staphylococcus saprophyticus. Two genuses are Gram-positive. In order to search for antimicrobial substances from natural plants, eighteen plant materials being made of perilla leaf as well as spices including garlic and ginger were used. The effects of these vegetable and fruit juices on the growth of scalp bacterial strains were investigated. Garlic and lemon juices showed antimicrobial activities on the growth of twenty bacterial strains belonging to 4 kinds of species. Onion, spring onion and leek juices inhibited the growth of only one bacterial strains Bacillus megeterium MS13.

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Antioxidant Activity of Spatholobus suberectus Dunn (계혈등의 항산화 활성)

  • Lee, Eun-Hee;Noh, Mi-Ae;Cha, Bae-Cheon
    • Korean Journal of Pharmacognosy
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    • v.36 no.1 s.140
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    • pp.50-55
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    • 2005
  • Reactive oxygen species (ROS) are continuously produced at a high rate as a by-product obtained in the aerobic metabolism. A major portion of living organisms has defense system as superoxide dismutase or catalase against damage produced by ROS. Several lines of evidence provided that ROS appears to cause to develop aging and various diseases. Spatholobus suberectus Dunn has been known as a Korean folk medicine for promoting blood circulation and relieving blood stasis as anemia. In this study, we have investigated the antioxidant activities of Spatholobus suberectus Dunn in order to find the antioxidant substances from natural products. For various antioxidant experiment, the major antioxidant component was isolated from EtOAc extract of Spatholobus suberectus Dunn. This compound was identified as (-)-epicatechin by chemical and physical analysis.

Toxicological Studies on the Essential Oil of Eugenia caryophyllata Buds

  • Park, Hee-Juhn
    • Natural Product Sciences
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    • v.12 no.2
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    • pp.94-100
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    • 2006
  • The essential oil (EC-oil) obtained from the buds of Eugenia caryophyllata (Myrtaceae) was examined for its free radical-scavenging activity, cytotoxicity, and in vivo toxicity. To find the xenobiotic properties of EC-oil, serum thiobarbituric acid reactive substances (TBARS) level and hepatic drug-metabolizing enzyme activities were measured. It was found that EC-oil displayed xenobiotic properties like bromobenzene. The cytotoxicities of eugenol and of the EC-oil were greatly attenuated by the sulfhydryl-containing N-acetyl-L-cysteine (NAC), suggesting that eugenol was susceptible to nucleophilic sulfhydryl. In addition, eugenol also showed potent free radical-scavenging activity in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. Moreover, methyleugenol considerably exhibited less cytotoxicity and less potent free radical-scavenging activity than eugenol, and the cell viability of the methyleugenol was more increased with NAC treatment than the eugenol. These results indicate that the phenolic OH in eugenol may play a crucial role in both cytotoxicity and free radical-scavenging activity. The fashion on oxidative stress and hepatic drug-metabolizing enzyme activities of eugenol resembled those of bromobenznene.

Action of Asparagus racemosus Against Streptozotocin-Induced Oxidative Stress

  • Govindarajan, Raghavan;Vijayakumar, Madhavan;Rao, Chandana Venkateshwara;Kumar, Vivek;Rawat, Ajay Kumar Singh;Pushpangadan, Palpu
    • Natural Product Sciences
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    • v.10 no.4
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    • pp.177-181
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    • 2004
  • Antidiabetic treatment with tubers of Asparagus racemosus (Liliaceae) extract (l00 and 250 mg/kg body weight) for three weeks showed significant reduction in thiobarbituric acid reactive substances (TBARS) and glutathione reductase (GSH-R) in both liver and kidney. The treatment with A. racemosus significantly altered the glutathione (GSH) and GSH-R to be comparable with the control group. A. racemosus and glibenclamide treated rats showed decreased lipid peroxidation that is associated with increased activity of superoxide dismutase (SOD) and Catalase (CAT). The ability of A. racemosus on tissue lipid per oxidation and antioxidant status in diabetic animals has not been studied before. The result of this study thus shows that though, A. racemosus possesses moderate antidiabetic activity, but it exhibits potent antioxidant potential in diabetic conditions.

Thermal conductivity properties of cement matrix utilizing diatomite and silica gel (규조토 및 실리카겔을 혼입한 시멘트 경화체의 열전도율 특성)

  • Kim, Ki-Hoon;Pyeon, Su-Jeong;Lee, Sang-Soo;Song, Ha-Young
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2018.05a
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    • pp.230-231
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    • 2018
  • Recently, the danger for radioactive materials has become a hot topic. Beginning with the Chernobyl nuclear accident in 1996, in 2011, the Fukushima nuclear power plant in Japan suffered major damage such as large-scale casualties and radioactive dangerous area selection. Concerns about leakage of radioactive materials due to recent earthquakes have been deepening in Korea, such as Wolsong Nuclear Power Plant in Gyeongju, and there is a growing interest in the safety of radioactive materials through the media and the media. However, the route to exposure to radioactive materials is not limited to these large-scale nuclear accidents. Typical examples of this are radioactive substances exposed in daily life. In the case of radon gas, the danger is being revealed through current events programs and news, and natural radiation exposure is attracting attention.

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Operation Conditions for Continuous DAF Process with Domestic DAF Pump (국산 DAF 펌프가 적용된 연속 DAF 공정의 운전 조건)

  • An, Dae Myung;Lee, Chang Han;Ahn, Kab Hwan;Cho, Seok Ho;Kim, Seong-Soo
    • Journal of Korean Society of Water and Wastewater
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    • v.18 no.2
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    • pp.242-246
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    • 2004
  • Dissolved air flotation (DAF) is an effective solid/liquid separation process for low density particles, such as algal flocs, humus materials and clay particles produced from low turbidity water. The fraction of humic substances for natural organic matters (NOMs) are considered problematic in water because it can readily react with chlorine to form harmful by-products (trihalomethanes) and can be exposed to undesirable color, tastes and odors in drinking water. A broad class of NOMs includes fulvic acid, humic acid and humin. This paper will discuss the results from a study that performed with a DAF pump process using synthetic wastewater contained humic substance. Batch jar tests were performed to evaluate coagulant dose and recycle ratio on flotation efficiency.

A Study on the Method of Science Laboratory Waste Water by Absorbent at the Secondary School (학교 실험 폐수 처리 방안)

  • 장원일
    • Hwankyungkyoyuk
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    • v.2 no.1
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    • pp.92-99
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    • 1991
  • According to our secondary school curriculum for natural science and technical circles, there be used 353 of chemical reagents including 24 kinds of harmful and toxicant components. At present, most school are discharging their school laboratory waste water without any chemical and physical treatments. So as to solve the environmental problem for water pollution, this study tried to research a kind of adsorbant utilizing saw dust, wasted wood sources and designed the simple processing system using the adsorbent. This adsorbent was made by extracting lignin substances from raw saw dust under the solution of 0.5N-NaOH at the temperature of $100^{\circ}C$. Their metal removed rates was measured not only by processing of column and vessel. but also by comparing the standard solution and real waste water. The results were proved as more than 90(%) of the adsorptive efficiency on the average from Pb, Cd, Cu except Cr(VI)in case of the school experimental waste water soaked in vessels a long with 4g of the adsorbent for 24 hours. The new processing system enables to remove most harmful and toxicant metals by filtering, sedimenting and adsorbing at the low cost.

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Studies on the Antioxidative Ability of Methanol and Water Extracts from Orostachys japonicus A. Berger According to Harvest Times (채취 시기에 따른 와송 추출물의 항상화 활성 연구)

  • Choi, Sun-Young;Chung, Mi-Ja;Sung, Nak-Ju
    • The Korean Journal of Food And Nutrition
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    • v.21 no.2
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    • pp.157-164
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    • 2008
  • This study examined the antioxidant activity of methanol and water extracts from Orostachys japonicus A. Berger according to harvest times, by measuring electron donating ability(EDA), reducing power, superoxide dismutase(SOD)-like activity, thiobarbituric acid reactive substances(TBARS) and antioxidant activity within a linoleic acid emulsion. EDA increased proportionally with the extract concentration and the methanol extract had slightly stronger effects than the water extract. And reducing power and SOD-like activity were highest in the methanol extract. Overall, based on the data, the methanol extract of O. japonicus A. Berger harvested during $August{\sim}October$ presented the highest level of antioxidative activity and may be a good candidate as a natural antioxidant source.

Purification and Characterization of the Inhibitory Principle aganist Pancreatic Cholesterol Esterase from Ephedra herba (마황으로부터 췌장 Cholesterol Esterase 저해물질 분리 및 규명)

  • 김희숙;조은정;류병호;송병권;이태훈;서판길;류성호
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.28 no.4
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    • pp.816-821
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    • 1999
  • Cholesterol esterase(pCEH, pancreas cholesterol ester hydrolase, E.C.3.1.1.13) which is secreted from pancreas has been known as an important lipase for cholesterol uptake. cholesteryl acyl esters from a diet must be hydrolyzed to free cholesterol and fatty acid by cholesterol esterase before the absorption in small intestine. For the development of inhibitory substances from natural source, we screened many extracts of oriental herbs for the inhibition of cholesterol esterase in vitro. The ethanol extract of Ephedra herba showed strong inhibitory activity. Solvent fractionation and silica gel column chromatography with the extract lead to the purification of the inhibitory principle in Ephedra herba. Crystallized inhibitor was identified as ( ) ephedrine by using UV, FT IR, 1H NMR, 13C NMR and GC/Mass. These results suggest that ( ) ephedrine can be used as a potential lead compound for the development of inhibitor for cholesterol uptake by cholesterol esterase inhibition.

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Antimicrobial Effects of Naringenin alone and in Combination with Related Flavonoids (나린게닌의 항균력에 미치는 관련 후라보노이드의 병용효과)

  • Han, Seong-Sun;Lee, Chong-Kil;Kim, Young-Soe
    • YAKHAK HOEJI
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    • v.36 no.5
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    • pp.407-411
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    • 1992
  • As part of our search for less toxic antimicrobial substances from natural resources, naringin was isolated from feels of Citri fructus and then hydrolyzed to naringenin. The antimicrobial activity of naringenin was examined by measuring the minimal inhibitory concentration(MIC) against fourteen species of bacteria. The antimicrobial activity of narngenin in combination with rutin or hesperetin was evaluated by checkerboard method. Among fourteen species tested, the antimicrobial activity of naringenin was the most prominant against Staphylococcus aureus and Shigella boydii showing MIC of $100\;{\mu}g/ml$ for both species. Combinations of naringenin with rutin or hesperetin showed synergism against several species of bacteria, but no antagonism was observed.

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