• 제목/요약/키워드: Natural Products Research Institute

검색결과 1,854건 처리시간 0.027초

Inhibitors of $5\alpha$-Reductase from the Roots of Angelica koreana

  • Seo, Eun-Kyoung;Kim, Kyeong-Ho;Kim, Min-Ki;Park, Eun-Wook;Kim, Ki-Nam;Lee, Hyun-Tai;Park, Hye-Young;Han, Ah-Reum;Mar, Wong-Chon
    • 대한약학회:학술대회논문집
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    • 대한약학회 2001년도 Proceedings of International Convention of the Pharmaceutical Society of Korea
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    • pp.267.3-268
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    • 2001
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A Monoacyldigalactosyl Glycerol from the Green Alga Enteromorpha prolifera

  • Kim, Ju-Sun;Shim, Sang-Hee;Lee, Sang-Hyun;Chae, Sung-Wook;Han, Sang-Jun;Kang, Sam-Sik;Lee, Yeon-Sil;Jung, Sang-Hoon;Shin, Kuk-Hyun
    • Natural Product Sciences
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    • 제10권6호
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    • pp.341-343
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    • 2004
  • A monoacyldigalactosyl glycerol was isolated from the $CH_2Cl_2$ soluble fraction of the MeOH extract from the green alga Enteromorpha prolifera. The structure was established as $1-O-palmitoyl-3-O-[{\alpha}-D-galactopyranosyl(1{\rightarrow}6)-{\beta}-D-galactopyranosyl]-sn-glycerol$ (1) by chemical and spectroscopic methods.

Effect of red ginseng NaturalGEL on skin aging

  • Kim, Ye Hyang;Park, Hye Rim;Cha, So Yoon;Lee, So Hun;Jo, Jung Wung;Go, Jung Nam;Lee, Kang Hyuk;Lee, Su Yeon;Shin, Song Seok
    • Journal of Ginseng Research
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    • 제44권1호
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    • pp.115-122
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    • 2020
  • Background: In aged skin, degradation of collagen fibers, which occupy the majority of the extracellular matrix in the dermis, and changes of aquaporin 3 (AQP3) and skin constituents, such as hyaluronic acid and ceramide, cause wrinkles and decrease skin moisturization to contribute to dryness and lower elasticity skin. Red ginseng (RG) is used as a cosmetic and food material and is known to protect from UVB-induced cell death, increase skin hydration, prevent wrinkles, and have an antioxidative effect. But, in general, RG used as a material is the soluble liquid portion in the solvent, and the part that is not soluble in the solvent is discarded. Thus, we made the whole RG into microgranulation and dispersed in water to produce gel form for using entire RG, and it was named red ginseng NaturalGEL (RG NGEL). Methods: RG NGEL was investigated for matrix metalloproteinases inhibitory activity, induction of Type I collagen, AQP3, hyaluronan synthetase 2, serine palmitoyl transferase, ceramide synthase 3, and filaggrin expression and compared with RG water extract. Results: RG NGEL reduced the levels of UV-induced matrix metalloproteinases and increased Type I collagen in human fibroblast cells and upregulated AQP3, hyaluronan synthetase 2, serine palmitoyl transferase, ceramide synthase 3, and filaggrin expressions in human keratinocytes compared with RG water extract. Conclusion: RG NGEL has the potential as an effective reagent for antiaging cosmetics to improve wrinkle formation and skin hydration.

Analgesic and Hypothermic Activities of Melandrin

  • Lee, Eun-Bang;Cheon, Seon-Ah;Lee, Young-Soon;Chung, Ha-Sook;Woo, Won-Sick
    • Archives of Pharmacal Research
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    • 제18권1호
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    • pp.38-40
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    • 1995
  • melandrin exhibited an analgesic activity as assessed by inhibition of writhing syndromein mice and by pressure method of inflamed paws of arts and inflamed tails of mmice, and showed a hypothermic effect. However, no anti-inflammatory activity was shown.

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