• Title/Summary/Keyword: National health

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Antimalarial effect of synthetic endoperoxide on synchronized Plasmodium chabaudi infected mice

  • Nagwa S. M. Aly;Hiroaki Matsumori;Thi Quyen Dinh;Akira Sato;Shin-Ichi Miyoshi;Kyung-Soo Chang;Hak Sun Yu;Fumie Kobayashi;Hye-Sook Kim
    • Parasites, Hosts and Diseases
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    • v.61 no.1
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    • pp.33-41
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    • 2023
  • The discovery of new antimalarial drugs can be developed using asynchronized Plasmodium berghei malaria parasites in vivo in mice. Studies on a particular stage are also required to assess the effectiveness and mode of action of drugs. In this report, we used endoperoxide 6-(1,2,6,7-tetraoxaspiro [7.11] nonadec-4-yl) hexan-1-ol (N-251) as a model antimalarial compound on P. chabaudi parasites. We examined the antimalarial effect of N-251 against ring-stage- and trophozoite-stage-rich P. chabaudi parasites and asynchronized P. berghei parasites using the 4-day suppressive test. The ED50 values were 27, 22, and 22 mg/kg, respectively, and the antimalarial activity of N-251 was verified in both rodent malaria parasites. To assess the stage-specific effect of N-251 in vivo, we evaluated the change of parasitemia and distribution of parasite stages using ring-stage- and trophozoite-stage-rich P. chabaudi parasites with one-day drug administration for one life cycle. We discovered that the parasitemias decreased after 13 and 9 hours post-treatment in the ring-stage- and trophozoite-stage-rich groups, respectively. Additionally, in the ring-stage-rich N-251 treated group, the ring-stage parasites hindered trophozoite parasite development. For the trophozoite-stage-rich N-251 treated group, the distribution of the trophozoite stage was maintained without a change in parasitemia until 9 hours. Because of these findings, it can be concluded that N-251 suppressed the trophozoite stage but not the ring stage. We report for the first time that N-251 specifically suppresses the trophozoite stage using P. chabaudi in mice. The results show that P. chabaudi is a reliable model for the characterization of stage-specific antimalarial effects.

Bacterial Contamination in Disposable Wet Wipes in General Restaurants 2nd (대중음식점 일회용 물티슈의 세균 오염도 조사(2))

  • Chong, Moo-Sang
    • Korean Journal of Clinical Laboratory Science
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    • v.54 no.1
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    • pp.23-27
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    • 2022
  • Disposable wet wipes provided by general restaurants in the Jeju Special Self-Governing Province were evaluated for compliance with the labeling requirements and the degree of bacterial contamination set by the Ministry of Food and Drug Safety. Of the 32 types of disposable wipes, five types of disposable wipes did not indicate the name and location of the business office of the manufacturer. Only 12 types of wet wipes were marked with the date of manufacture and expiration date. Bacterial contamination was seen in 9 types of wet wipes through bacterial culture but these were absent in the remaining 23 types (71.9%). The results of the antimicrobial susceptibility test for the 9 identified strains showed no methicillin-resistant coagulase-negative staphylococci (MRCNS) or multidrug-resistant bacteria. Through this study, it is recommended that the date of manufacture and expiration date must be indicated on the surface of disposable wet wipes designated as hygiene products, and clean uncontaminated wet wipes must comply with storage standards. In addition, the results are expected to contribute to the enhancement and improvement of hygiene management supervision, personal hygiene management, and an improvement in national health.

A Study of the Stability on Standing posture of Single leg in Yoga practicing (요가 수련을 통한 한발서기 자세의 안정화 연구)

  • Yoo, Sil;Hong, Su-yeon;Yoo, Sun-sik
    • 한국체육학회지인문사회과학편
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    • v.55 no.6
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    • pp.749-757
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    • 2016
  • The purpose of this study was to investigate the effect of stability on one leg standing posture in yoga practice. Thirteen women college student who have never done yoga participated in this study. In order to collect data before and after yoga practicing for two years, we were used 3D motion capture system and electromyography. The results were as follows. First, ranges of motions for Y axis of left knee joint and X axis of right ankle joint were significantly different in dancer posture(p<.05), and then X axis of right ankle and Y axis of left ankle joint were significantly different in tree posture of pre and post training. Second, the planar alignment angle of trunk-pelvis was not significant difference in dancer and tree posture. Third, CoM-distances of Y, Z directions were significant difference in the tree posture(p<.05). Fourth, Muscle activities of both rectus abdominis, erector spinae and left quadriceps were significant difference in tree posture(p<.05). These findings suggested that yoga training played important roles in stable postures as results of decreasing rotation ankle joint and movement of CoM and enforcing core muscles. This study provides evidence for effectiveness of the stability on standing posture and can get a great effect on posture correction by means of yoga training. Hereafter, study on alignment angle, which is a measurement of postural stabilization will be needed by future yoga training.

Finding Pointing Spot of Korean Sports Culture and Alternative to its Advancement (한국 스포츠문화의 지향점과 선진화 대안 찾기)

  • Kim, Young-Kab
    • 한국체육학회지인문사회과학편
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    • v.54 no.1
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    • pp.47-55
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    • 2015
  • This study is to examine the current situation of Korean sports culture and seek its pointing spot and alternatives to its advancement. First, out of the current situation of Korean sports culture, that of school physical education, even though it is the most significant basis for sports culture, is riddled with so many contradictions that the pace of its change is very slow. Only when the elite sport is normally operated and well coordinated, can it have the value of existence as a stable field. The mass sports have been determined to have insufficient self-reliance of sport facilities, sport programs and instructor management since the national policy for physical education has been focused on the elite sports. Second, internalization of "Winning First Policy" as a pointing spot of sports culture has been found to be an production of the value system with not only a very passive tendency caused by political changes. Accordingly, the concept of sports-culturism has been introduced as a new pointing spot of sports culture and then it has been emphasized that the sports-culturism is the awareness of sports advancement. Third, in terms of finding any alternatives to sports culture, enacting a school physical education promotion law has a very significant meaning as its advancement method. Next, the immorality of and match-fixing by sport organizations and the umpire's bad call have been mentioned as major problems to the elite sport, and also the alternative to each field has been set. Last, it has been assented with emphasis that Law of Sports for All should be enacted for the public sports to have any significance of the times.

A Study of Kano Jigoro's Philosophical Viewpoint of Joseon: Focusing on Martial Art Philosophy (가노지고로의 조선관 연구: 무도사상을 중심으로)

  • Yoo, Sung-Yeon
    • 한국체육학회지인문사회과학편
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    • v.57 no.5
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    • pp.1-11
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    • 2018
  • The purpose of this study was to investigate the views of Joseon held by Kano Jigoro, who was the creator of judo and spread the martial arts ideology across the world, to shed light on the fundamental essence of the martial arts ideology spread around Korea. Conducted in this perspective, the study generated the following results: first, Kano Jigoro grew up, receiving history education from classical scholars of Japan. He was accordingly influenced by the Seikanron, which argues that Empress Jingu, a mythical character, conquered Silla, Baekje and Gaya. The Seikanron became the basis of the Imna Ilbonbu theory during the Japanese rule and was projected onto martial arts ideas Jeongryeokseonyong and Jatagongyeong that were completed by Kano Jigoro and introduced into Joseon. Secondly, Kano Jigoro distributed and expanded the tale of statehood in the prism of martial arts ideology since the Meiji Restoration, which was possible because he connected his martial arts ideas to the statehood of Japan. As a result, they were used as the logic of Korea and Japan are One in Joseon unlike the rest of the world where they were applied as peace ideas. Finally, his martial arts ideology introduced into Joseon during the Japanese rule went through acculturation and showed the contradiction of being interpreted differently according to different individuals. Most Japanese people made use of his martial arts as a means of the Korea and Japan are One policy, whereas the pioneers of the Korean people excluded Kano Jigoro's view of state, included the nationalistic features in it, and trained their martial arts as a means of overcoming the national crisis.

The process of transformation experience in yoga participants through Causal Network (인과 네트워크로 본 요가 참여자의 변화체험 과정)

  • Kwon, Oh-Jung
    • 한국체육학회지인문사회과학편
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    • v.54 no.5
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    • pp.233-250
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    • 2015
  • In this study, changes and emotions that result from doing yoga and the influence of yoga on daily lives were investigated by using causal network. This information was gathered from interviews and outlined in a diagram form. By checking the daily participation records of 77 participants who took a yoga class as part of the cultural studies curriculum at H University, general factors related to change were extracted and then 7 participants were chosen for in-depth interviews. In the interviews, the changes experienced from doing yoga and the emotions caused by the change and the influence this change had on daily lives were documented and the collected results were displayed in a diagram using causal network according to the flow of questionnaire. As a result, the changes experienced through doing yoga were divided in 4 categories: physical function, emotional, cognitive and physiological changes. Each change and emotion caused by the change were shown to have an influence on daily lives. Through schematized causal network for each change, the changes and emotions which the participants experienced and the influence of yoga on daily lives could be checked. Based on the study results, the effect of yoga, the need for various approaches to examine the effect exercise has on emotions and the applicability of causal network that can be employed as a creative and effective quantitative data analysis method were discussed.

A Study on Attributes to Select the Physical Education Institutes for Preschoolers in Directors of Educational Institutes for Preschoolers (유아교육기관장의 유아체육교육기관에 대한 선택속성 연구)

  • Choo, Nayoung
    • 한국체육학회지인문사회과학편
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    • v.55 no.4
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    • pp.241-252
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    • 2016
  • The purpose of this study was to suggest rating factors of the importance and the satisfaction for selecting physical education institutes for preschoolers and to provide an implication of vitalizing physical education class for preschooler with comparative analysis between importance and satisfaction using IPA analysis. 253 directors of educational institutes for preschooler have chosen through a convenience sampling method, and 430 was used for analysis. The results were as follows. First, the instructor qualification items and the program items ranked highly positions in physical education institute for preschooler. Second, the instructor qualification items, the program items, tuition items of discount benefit and institution image items of reputation had the significant difference between importance and satisfaction. Lastly, The quadrant I is "the keep up the good work" part and includes 8 items such as the expertise of the physical education teacher for preschooler. The quadrant II is "the concentrate here" part and includes 2 items such as teaching ability of the physical education teacher for preschooler. The quadrant III is "the low priority" part and includes 6 items such as reasonable prices of tuitions.

Perception of kimchi and Preference of foods using kimchi in School Meals - Focused on High School Students in Gwangju - (학교급식 김치에 대한 인식과 김치응용요리 선호도 - 광주지역 고등학생을 중심으로 -)

  • Kim, Eun-Young;Park, Young-Hee;Jung, Lan-Hee;Jeon, Eun-Raye
    • Journal of the Korean Society of Food Culture
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    • v.25 no.3
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    • pp.241-250
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    • 2010
  • This study was conducted to improve the kimchi intake for high school students of various kimchi sub-ingredients and foods using kimchi. The students believed that kimchi is good for health. The overall satisfaction, baechu quality and the taste and degree of fermentation of kimchi was high, but there was a low preference for offered kimchi kinds, kimchi subingredient, foods using kimchi. The types of kimchi preferred and often offered in school meals were baechu-kimchi and kkakdugi. The common kimchi sub-ingredients were radish and welsh onion in vegetables, squid and oyster in sea foods, saeu-jeot and myeolchi-jeot in salted fish, and pear and apple in fruits. The preference for kimchi sub-ingredients were high for sesame leaf and yeolmu in vegetables, saeu-sal and squid in sea foods, saeu-jeot and nakji-jeot in salted fish, and pear and apple in fruits. The foods using kimchi preferred and often offered with school meals were kimchi-jjigae, bokkeumkimchi, kimchi soup, kimchi-bokkeum-bap, and kimchi-jeon. The kimchi sub-ingredient for which students had the greatest preference was meats. Among the foods using kimchi with meats, the most preferred were kimchi-pyeonyuk bossam, doejigogi kimchi duruchigi, and kimchi galbi-jjim. Among the foods using kimchi with noodles, the most preferred were kimchi- bibimmyeon, kimchi -naengmyeon, and kimchi-cheese spaghetti. Among the foods using kimchi with vegetables, the most preferred were kimchi-pa-jeon, kimchi- deopbap and kimchi- goguma gui. Of the foods using kimchi with processed foods, the most preferred were kimchi-mandu, kimchi-bacon jumeok-bap and kimchi- cheese omelet. Among the foods using kimchi containing sea food, kimchi-haemul bokkeum-bap, kimchi-hoe-deopbap, and kimchi-saeu-jjim were most preferred. Overall, these results suggest that various kimchi sub-ingredients and foods using kimchi should be improved for kimchi intake of school meals.

A Study on the Learning Community Participation According to Learner Characteristics (학습자 특성에 따른 학습공동체 참여 차이에 관한 연구)

  • KIM KYUNG HEE;CHOI JOO YOUNG
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.2
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    • pp.199-206
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    • 2023
  • This study attempted to examine the relationship between college students' participation in the learning community according to the characteristics of learners. To this end, the learning community divided the subject-linked learning community into a foundation learning community and an advanced learning community. Learner characteristics were classified by gender, grade, and major. A cross-analysis was conducted to examine the difference between participation in the foundation learning community and the advanced learning community according to the learner characteristics. The results are as follows. First, the participation of female students in the foundation learning community and the advanced learning community was higher than that of male students, but it was not statistically significant. Second, it was found that there was a significant difference in participation in the learning community according to the grade. In the case of the foundation learning community, the participation rate of the first and second year students was relatively high, and in the case of the advanced learning community, the ratio of the third and fourth year students was relatively high. Third, as a result of examining the differences by major, it was found that the participation rate of health and welfare universities was high in both the foundation learning community and the advanced learning community. Based on these results, discussions and suggestions are presented.

The Development of Web-based Nutrition Information Contents for Older Adults : Content Analysis and Card-sorting process (노인대상 영양정보 웹사이트 컨텐츠 개발 : 내용분석과 카드소팅과정(Card-sorting process))

  • Chae, In-Sook;Yang, Il-Sun;Lee, Pil-Soon;Chung, Yoo-Sun;Kim, Young-Shin;Jang, Yoon-Jung
    • Journal of the Korean Society of Food Culture
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    • v.22 no.2
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    • pp.235-245
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    • 2007
  • This study was undertaken to develop web-based nutrition information contents for the older adults. Twenty six domestic web-sites were analyzed and then 12 foreign web-sites and 4 education materials for the elderly of foreign university were benchmarked. Also a lot of literatures on elderly education program were reviewed. A card-sorting task was performed with 8 older adults to ascertain how the target audience organized information about nutrition. The results were as fellows. Among 26 domestic web-sites, 2 sites(7.7%) were only for the elderly. Main topics of information contents for the elderly included 'Importance of Healthy Eating', 'DRI', 'Dietary Guidelines'. Four of twelve foreign web-sites were for the elderly nutrition education. Topics of 'Dietary Guideline', 'Meal Program' were found in 4 sites and 'Importance of Healthy Eating', 'Diet & Disease', 'DRI, 'Food Guide Pyramid', 'Nutrition Fact Labels' were found in 3 sites. Education materials of foreign university dealt with basic information on 'nutrient needs changes related with aging', 'Heart & Bone Healthy Eating Plan', 'Food Guide Pyramid'. Also topics on 'Eating on a budget', 'Eating Out Guideline' were included for practical use for the elderly. Based on card-sorting process, contents framework for web-site was developed and 4 main menus for framework were respectively named as 'Nutrition', 'Meals', 'Foods'. 'Check up Nutritional Health' by panel discussion. Finally we developed nutrition information contents for 4 main menus. We focused on helping older adults recognize the importance of healthy eating and apply the nutrition information to practical use. We expect that the developed framework of contents can be a guideline for indentifying the information needs of older adults in developing effective nutrition intervention program. And we suggest that the survey for target people should be peformed for the web-site to be user-friendly designed and the developed contents be evaluated and revised in the near future.