• Korean Journal of Fisheries and Aquatic Sciences
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• v.29 no.2
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• pp.246-255
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• 1996

To develop a natural antioxidative peptide, the gelatin was extracted from fish (Yellowfin sole) skin by hot $water(50^{\circ}C)$ extraction method and hydrolyzed with Alcalase, pronase and collagenase through a continuous 3-step membrane reactor. Each step enzymatic hydrolysates were determined the antioxidative activity and their synergistic effects, compared with $\alpha-tocopherol$ and butylated hydroxytoluene (BHT). Also, we tried to investigate the antioxidative disposition of peptide which was successfully separated by gel filtration, ion-exchange chromatography, and HPIC in cultured rat hepatocytes intoxicated with tert-butyl hydroperoxide (TBHP). Second step enzymatic hydrolysate (SSEH) among all hydrolysates and $\alpha-tocoperol$ was showed the strongest antioxidative activity. The optimum concentration of antioxidative activity for SSEH was $1\%(w/w)$ in linoleic acid. The synergistic effects were increased in using the hydrolysate with tocopherol and BHT. In the presence of the peptide isolated from SSEH, supplemented hepatocytes exposed to TBHP showed that delayed cell killing and decreased significantly the lipid peroxidation, compared with hepatocytes not cultured with isolated peptide.

• Journal of Veterinary Clinics
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• v.23 no.2
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• pp.87-90
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• 2006

The aim of the present study was to investigate the disposition pharmacokinetics of roxithromycin in broilers. Roxithromycin was administered at a single dose of 20 mg/kg body weight by intravenous (i.v.) routes. Plasma concentrations of roxithromycin were determined by liquid chromatography/mass spectrometry. After a single i.v. dose plasma concentrations were best fitted to a two-compartment open model. The values of the pharmacokinetic parameters after i.v. administration were: elimination half-life = $5.83{\pm}1.79h$, mean residence time = $6.33{\pm}0.32h$, total body clearance = $0.55{\pm}0.15L/h/kg$, and volume of distribution at steady state = $3.47{\pm}0.84L/kg$. The pharmacokinetic interpretation of roxithromycin after i.v. administration revealed that the drug was well distributed throughout the body in broilers and slowly eliminated. More studies for the application of roxithromycin against poultry disease are needed to establish a suitable pharmaceutical formulation, propose optimum dosage regimens, investigate clinical efficacy and study the tolerability of repeated doses.

• THE INTERNATIONAL COMMERCE & LAW REVIEW
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• v.43
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• pp.201-238
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• 2009

The purpose of this paper is to describe the contents and issues of the draft legislation of Part VI the Carriage by Air of Korean Commercial Code in respect of the domestic carriage of cargo by air, comparing to the related provisions of the Montreal Convention of 1999 for the unification of certain rules for international carriage by air and the related provisions of Korean Commercial Code in respect of the carriage by land and sea. The Montreal Convention in respect of the international carriage by air was adopted in 1999, and Korea has ratified the Montreal Convention in 2007. However, there is now no national legislation in respect of the carriage by air in Korea. Thus, the Ministry of Justice has prepared the draft legislation of Part VI the Carriage by Air of the Korean Commercial Code in July 2008, and the draft legislation is now being reviewed by the National Assembly. The draft provisions of Part VI the Carriage by Air are basically adopting most of the related provisions of the Montreal Convention in respect of the carriage of cargo by air and some draft provisions are applying the related provisions of the Korean Commercial Code in respect of the carriage of cargo by land and sea. In respect of the carriage of cargo by air, the contents of the draft legislation of Part VI the Carriage by Air are composed of the provisions in respect of the liability of the carrier, the rights of the consignor and consignee, the transport document and others. In respect of the carriage of cargo by air, the issues on the draft legislation of Part VI the Carriage by Air are the problems with respect to the extinguishment of the liability of the carrier, the application for the non-contractual claim, the liability limit of the servants or agents of the carrier, the right of disposition of cargo, the effect of breach of the provision in respect of the air transport document, the prescription of claim of the carrier, the immunity reasons from liability of the carrier for the loss or damage of the cargo, the making out of the air waybill, and the effect of the statement of the air transport document. In conclusion, the national legislation of Part VI the Carriage by Air of the Korean Commercial Code will protect the right and interest of the consignor and consignee, and clarify the right and duty of the parties to the air transport. Also it will contribute to the development of the air transport industry in Korea.

• The Korean Journal of Pharmacology
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• v.32 no.2
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• pp.269-281
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• 1996

Pharmacokinetics of prednisolone and prednisone undergoing reversible interconversion were analyzed from the model including this metabolic process. Blood samples were drawn serially upto 12 hours after I,V. bolus injection of 1 mg/kg prednisolone sodium phosphate and prednisone into 8 dogs as a crossover manner. Plasma concentrations of those two steroids were simultaneously measured with the method of HPLC. After injection, plasma concentrations of administered prednisolone and prednisone were declined with a biexponential pattern and their metabolic partner was rapidly formed. Plasma concentrations of those metaboite were decayed in parallel with their parent steroids throught the elimination phase. Apparent clearances of prednisolone and prednisone were $11.1{\pm}2.0\;ml/min/kg$ and $45.9{\pm}6.4\;ml/min/kg$, and they were underestimated by 29.4% and 33.6% compared to their real clearances$(15.7{\pm}4.4\;and\;69.2{\pm}17.7\;ml/min/kg)$ estimated using reversible interconversion model. Apparent volume of distribution of prednisolone$(1.32{\pm}0.43\;L/kg)$ and prednisone$(4.81{\pm}2.75\;L/kg)$ were overestimated by 53.5 and 52.7% and were compared to the real volumes $(0.86{\pm}0.30\;and\;3.15{\pm}2.13\;L/kg)$. Mean residence time of prednisolone$(2.0{\pm}0.61\;h)$ and prednisone$(1.74{\pm}0.74\;h)$ were much longer than the real sojourn time$(0.93{\pm}0.26\;and\;0.88{\pm}0.54\;h)$. Essential clearances In the reversible interconversion were greater as following orders: $Cl_{21}$(44.3 ml/min/kg) > $Cl_{20}$(24.2 ml/min/kg) > $Cl_{12}$ (7.9 ml/min/kg) > $Cl_{10}$(7.8 ml/min/kg). Estimated mean values of RF, EE, $%X^1_{ss}$ and $RHO^2_1$ were $0.31{\pm}0.10$, $1.49{\pm}0.23$, $69.3{\pm}16.7%$ and $0.65{\pm}0.10$, respectively. These results suggested that true pharmacokinetic parameters estimated from the model including reversible interconversion were significantly different from the apparent parameters estimated from the conventional mamillary model, and disposition of these two steroids seemed to be well explained by the model including reversible interconversion.

• Journal of Gifted/Talented Education
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• v.18 no.2
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• pp.265-292
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• 2008

This thesis was projected for the purpose of looking into the recongnition of the talented children education, classifying with parents' up-bringing styles, and it classified parents' upbringing styles with affection, refusal, and autonomy, aiming at 189 parents whose children are enrolled in public kindergartens located at three urban districts, J City, G City, and I City, and four rural districts, J County, M County, O County, and I County, and investigated the recongnition for the talented children education,, basing on four kinds of inclination. The results are as followings. First, it is important to activate parent education for the talented children, to help parents, who bring up children with refusal attitude, to give their children sufficient affection, to offer children the chances to express freely and explore, to give children possible permission, and to accept children completely, Second, the cultivated experts with specialized culture and disposition are necessary to grasp the peculiarity of talented children in respective fields. Third, the establishment of the expert talented children education institution specializing in research is necessary Fourth, at the national level, no-fee education for the talented children has to be carried into effect, the national talented children education agencies have to be established widely, researches for the talented children have to be established, the experts for educating talented children have to be brought up, and research expenses have to be supplied to respective talented children education agencies.

• Environmental and Resource Economics Review
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• v.27 no.3
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• pp.399-420
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• 2018

This study has attempted environmental economic analysis on the cost structure of offshore fisheries based on fishery management data published by the Fisheries Research Institute to examine the effect of the environmental policy on the fisheries for the effective implementation of the Paris Convention. Under the assumption that both fisheries and carbon dioxide are simultaneously produced, the cost structure of offshore fisheries were analyzed. Cost function in a translog form was estimated and SUR (Seemingly Unrelated Regression) model was used for the analysis. Here, $CO_2$ emission of offshore fishery was calculated by using National Federation of Fisheries Cooperatives' data on supply of tax exemption oil (2003~2016). The cost function estimation showed that there is a weak disposition between catches and $CO_2$ emissions during the sample period, and the marginal abatement cost (MAC) is estimated at 1,457 won per year. In addition, for the same period, when 1% of $CO_2$ per horsepower is to be reduced MAC increases by 2.2%, and when 1% of $CO_2$ per 1 ton of catch is to be reduced, MAC increases by 1.4%.

• Journal of Digital Convergence
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• v.19 no.6
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• pp.185-198
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• 2021

This study is a study to examine and verify the importance of human resources among the various factors that modern companies need to consider in order to cope with the changing environment. As independent variables, acquiescent and defensive silence were composed of the motives felt by members, and creativity and innovation behavior were set as the outcome variables. Through this research, first, the importance of communication between the members of the organization and the manager is investigated, and it is intended to be managed efficiently. Secondly, we would like to confirm the modulating effect of resilience in the relationship between them, and to find out the importance of psychological recovery of members. In the end, this aims to talk about the importance of psychological management and recovery of members in managing human resources. As a result, acquiescent silence negatively affects creativity and innovation behavior, and defensive silence positively affects creativity and innovation behavior. In addition, in the case of the moderating effect of resilience, there was no significant relationship in both defensive silence, creativity, and innovation behavior, and in the case of acquiescent silence, only innovation behavior was found to be significant. This is the result of the combination of the unique characteristics of resilience and the difference in the disposition of the members who choose resignation silence and defensive silence.

• Journal of the Korean association of regional geographers
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• v.16 no.3
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• pp.324-337
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• 2010

We believe, 'Dokdo is clearly an inherent territory of Korea, in the light of geographical and historical facts', This paper aims to discuss Japanese multidimensional approach on the Issues of Dokdo(Takeshima) in the context of Territory Education. We considered the matter from various angles that supported by the ministry of Foreign affairs and the ministry of Education in national scale, as well as shimane prefecture government and municipality scale. Therefore, It is likely that the approach of territory education on Dokdo in Japan is variable and potential, and is temporary state of condensation, depends on Korea-Japan's political, economical, social, and international conditions. More studies of the new approach must be done for the new implications of Territory Education that embraces all meanings and events according to the disposition of neighbouring condition of Dokdo in world context, keeping out emotional and nationalist sympathies. The result of consideration in this paper are as follows. First, Territory Education in japan was focused on geography, history, Civil, Social Studies, compared with focusing on History in Korea. Second, It is centered on "korea is illegally occupying Dokdo, against which Japan has been consistently making strong protests" rather than simple historical approach. Thirdly, Their approaches seek to be succeeded the identity and importance of Territory Education to next generation rather than the present solving problem.

• Journal of the Korean Institute of Landscape Architecture
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• v.34 no.6 s.119
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• pp.10-21
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• 2007

The purpose of this paper was to classify areas demanding to be transformed to green spaces and evaluate their grades for urban park and green networks. The results of this study are summarized below; 1. The results of the classified green spaces in the research areas fall into three types including children parks, neighborhood parks, and public green spaces. The three types of green spaces were analysed with recreational indexes. The zones disturbing the green-networks were sorted out. These zones should be changed into a supplementary green spaces for improving the recreational functions in the city. 2. For urban park and green networks, distances between the parks and size of the parks were adopted as indices. Based on the index of distances between the parks, disturbing zones were evaluated with 3 grades. The first grade includes primary industrial complexes and housing complexes. The second grade was observed mostly in industrial complex areas. The third grade includes housing complexes. Based on the indexes of size of parks, disturbing zones were evaluated with 2 grades. In the case of grade I, it appeared in housing complex. In the case of grade II, it appeared in industrial complex. 3. Then, we prioritized the disturbing zones with severity in order to make supplementary green spaces. Through the process, the zones of the grade I for two each recreational index were evaluated to two grades. The analysis results of evaluated zones were that grade II appeared over industrial and housing complexes widely. Grade I appeared over housing complexes. 4. It is necessary that the grade of disturbing zones should be considered as an order to make green spaces to supplement a green-network. For this, we formed a basic frame of a green-networks in Dalsu-Gu and placed the disturbing zones on the basic frame of a green-network. Consequently, The results were that the green-networks in Dalsu-Gu was composed on four green-network axes and its shape mirrored a cruciform (+) of northwest$\leftrightarrow$southeast direction and southwest$\leftrightarrow$northeast direction.

• Journal of Science Education
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• v.38 no.2
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• pp.401-414
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• 2014

Overexcitability (OE) and social self-concept are the integral affective characteristics of science-gifted students. Overexcitability refers to sensitivity as an internal disposition to give a more often, longer and more intensive reaction to a wide variety of stimuli, and social self-concept refers to the way of behaving in society, especially at school in the case of students. The purpose of this study was to examine the overexcitability and social self-concept of science-gifted and non-gifted elementary school students. The subjects in this study were 135 gifted elementary students belonged to gifted education centers or gifted classes and 91 ordinary elementary students. An overexcitability test and a social self-concept test were conducted to the subjects, and the collected data were analyzed by SPSS. The findings of the study were as follows: First, the score of the science-gifted was significantly higher than that of the ordinary students in all sub-domain of OE (psychomotor OE, sensual OE, emotional OE, intellectual OE, emotional OE) and social self-concept. Second, the science-gifted students who attended gifted education centers and community gifted classes scored significantly higher than the ordinary students in overexcitability. Based on conclusions, implications for teaching the science-gifted were discussed.