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Effects of Supplemental Recombinant Bovine Somatotropin (rbST) and Cooling with Misters and Fans on Renal Function in Relation to Regulation of Body Fluids in Different Stages of Lactation in Crossbred Holstein Cattle

  • Boonsanit, D.;Chanpongsang, S.;Chaiyabutr, N.
    • Asian-Australasian Journal of Animal Sciences
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    • v.23 no.3
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    • pp.355-365
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    • 2010
  • The aim of this study was to investigate the effect of supplemental recombinant bovine somatotropin (rbST) and cooling with misters and fans on renal function in relation to regulation of body fluids in different stages of lactation in crossbred Holstein cattle. Ten, 87.5% crossbred Holstein cattle were divided into two groups of 5 animals each, housing in a normal shaded barn (NS) and in a shaded barn with a mister-fans cooling system (MF). The experiment in each group was divided into 3 phases, early- (Day 75 postpartum), mid- (Day 135 postpartum), and late stage of lactation (Day 195 postpartum). The pre-treatment study was conducted on the starting day of each stage of lactation and the treatment study was performed after the end of the pre-treatment, during which the animal was injected with 500 mg of rbST (POSILAC) every 14 days for three times. During the study, ambient temperature at the hottest period daily in the MF barn was significantly lower, while relative humidity was higher than that of the NS barn. The temperature humidity index (THI) in both barns ranged from 79-85 throughout the periods of study. Cows in the MF barn showed a lower rectal temperature and respiration rate as compared with cows in the NS barn. The effect of rbST administration increased both rectal temperature and respiration rates of cows housed in either the NS or MF barn. Milk yield significantly increased in cows treated with rbST in all stages of lactation. Increases in mammary blood flow, accompanied by increases of total body water (TBW), extracellular fluid (ECF), blood volume (BV) and plasma volume (PV), were observed in both groups of cows receiving rbST in all stages of lactation. No alterations of renal blood flow and glomerular filtration rate were observed in cows receiving rbST, but decreases in urinary excretion and fractional excretion of sodium, potassium and chloride ions appeared to correlate with reduction in the rate of urine flow and osmolar clearance during rbST administration. These results suggest that the effect of rbST supplementation to cows housed either in NS or MF barns on body fluid volume expansion is attributable to changes in the rate of electrolyte excretion by the kidney. The increased availability of renal tubular reabsorption of sodium, potassium and chloride ions during rbST treatment was a major factor in retaining body water through its colligative properties in exerting formation of an osmotic force mechanism.

Continuous Epidural Infusion of Bupivacaine with Tramadol for Post-Cesarean Analgesia (제왕절개술후 통증치료시 지속적 경막외 국소마취제와 Tramadol의 병용투여의 효과)

  • Kang, Po-Soon;Cho, Jae-Kun
    • The Korean Journal of Pain
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    • v.11 no.1
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    • pp.54-59
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    • 1998
  • Background: Tramadol administered epidurally is known to have one-thirtieth the potency of morphine for treatment of pain following abdominal surgery. We designed a prospective, randomized, controlled study to evaluate the analgesic efficacy and safety of combined epidural infusion of bupivacaine and tramadol with 2-day infusor as ompared to bupivacaine and morphine combined epidural infusion. Methods: Sixty healthy women scheduled for Cesarean delivery were assigned randomly in double- blind fashion: Group 1 (n=20) were given a mixture of morphine 10 mg(1 ml), 0.5% bupivacaine 40 ml and normal saline(NS) 40 ml; Group 2(n=20) a mixture of tramadol 300 mg(6 ml), 0.5% bupivacaine 40 ml and NS 54 ml; Group 3(n=20) or a mixture of tramadol 500 mg(10 ml), 0.5% bupivacaine 50 ml and NS 50 ml, of continuous dose via epidural route following 1% lidocaine 6 ml as bolus dose for 48 hours postoperatively. We evaluated the analgesic efficacy and side effects of these three groups using visual analogue pain scale (VAPS) and verbal rating scale (VRS). Results: VAPS of group 1 and 3 were lower than group 2, and VAPS of group 1 was lower than group 3(12, 24, 36, 48 hours). VRS of group 1 and 3 were lower than group 2 (12, 24, 36 hours). There were incidences of pruritus was 16 patients in group 1. Conclusions: Tramadol does possess the analgesia effect of morphine, but has the added analgesia following increment. Further research to determine the most effective administration method and reguired dosage of tramadol is further needed.

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Detection of atypical porcine pestivirus (APPV) from a case of congenital tremor in Korea (포유자돈 선천성 진전증 증례에서 atypical porcine pestivirus (APPV) 검출)

  • Kim, Seung-Chai;Jeong, Chang-Gi;Yoon, Seung-Min;Lee, Ki-Ho;Yang, Myoun-Sik;Kim, Bumseok;Lee, Seung-Yoon;Kang, Seog-Jin;Kim, Won-Il
    • Korean Journal of Veterinary Service
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    • v.40 no.3
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    • pp.209-213
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    • 2017
  • Congenital tremor (CT) is a sporadic neurodegenerative disease reported in suckling piglets worldwide. Since atypical porcine pestivirus (APPV) was first identified in US in 2015, it has also subsequently detected in Europe and China as a causative pathogen for CT in suckling piglets. Three new-born piglets died from severe tremor was submitted to Chonbuk National University-Veterinary Diagnostic Center (CBNU-VDC) and various tissues (lung, lymph node, brain, intestine) were tested with panpestivirus RT-PCR and APPV NS5B-specific RT-PCR. All of the samples were positive by both of the PCR tests and the partial NS5B sequences of APPV were confirmed by sequencing on the PCR products of APPV NS5B-specific RT-PCR. Therefore, we report the first identification of APPV from a case of CT in suckling piglets in Korea.

Geological Structure of the Moisan Epithermal Au-Ag Mineralized Zone, Haenam and its Tectonic Environment at the Time of the Mineralization (해남 모이산 천열수 금-은 광호대의 지질구조와 광화작용 당시의 지구조환경)

  • Kang, Ji-Hoon;Lee, Deok-Seon;Ryoo, Chung-Ryul;Koh, Sang-Mo;Chi, Se-Jung
    • Economic and Environmental Geology
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    • v.44 no.5
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    • pp.413-431
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    • 2011
  • An Epithemal Au-Ag mineralized zone is developed in the Moisan area of Hwangsan-myeon, Haenam-gun, Jeol-lanam-do, Korea, which is located in the southwestern part of the Ogcheon metamorphic zone. It is hosted in the Hwangsan volcaniclastics of the Haenam Formation of the Late Cretaceous Yucheon Group. This research investigated the characteristics of bedding arrangement, fold, fault, fracture system, quartz vein and the time-relationship of the fracture system to understand the geological structure related to the formation of the mineralized zone. On the basis of this result, the tectonic environment at the time of the mineralization was considered. Beds mainly trend east-northeast and gently dip into north-northwest or south-southeast. Their poles have been rearranged by subhorizontal-upright open fold of (east)-northeast trend as well as dip-slip fault. Fracture system was formed through at least 6~7 different deformation events. D1 event; formation phase of the main fracture set of EW (D1-1) and NS (D1-2) trends with a good extensity, D2 event; that of the extension fracture of NW trend, and conjugate shear fracturing of the EW (dextral) and NS (sinistral) trends, D3 event; that of the extension fracture of NE trend, and conjugate shear refracturing of the EW (sinistral) and NS (dextral) trends, D4 event; that of the extension fracture of NS trend showing a poor extensity, D5 event; that of the extension fracture of NW trend, and conjugate shear refracturing of the EW (dextral) and NS (sinistral) trends, D6 event; that of the extension fracture of EW trend showing a poor extensity. Frequency distribution of fracture sets of each deformation event is D1-1 (19.73 %)> D1-2 (16.44 %)> D3=D5 (14.79 %)> D2 (13.70 %)> D4 (12.33 %)> D6 (8.22 %) in descending order. The average number of fracture sets within 1 meter at each deformation event is D6 (5.00)> D5 = D4 (4.67)> D2 (4.60)> D3 (4.13)> D1-1 (3.33)> D1-2 (2.83) in descending order. The average density of all fractures shows 4.20 fractures/1 m, that is, the average spacing of all fractures is more than 23.8 cm. The frequency distribution of quartz veins at each orientation is as follows: EW (52 %)> NW (28 %)> NS (12 %)> NE (8 %) trends in descending order. The average density of all quartz veins shows 4.14 veins/1 m, that is, the average spacing of all quartz veins is more than 24.2 cm. Microstructural data on the quartz veins indicate that the epithermal Au-Ag mineralization (ca. 77.9~73.1 Ma) in the Moisan area seems to occur mainly along the existing D1 fracture sets of EW and NS trends with a good extensity not under tectonic stress but non-deformational environment directly after epithermal rupture fracturing. The D1 fracturing is considered to occur under the unstable tectonic environment which alternates compression and tension of NS trend due to the oblique northward subduction of the Izanagi plate resulting in the igneous activity and deformation of the Yucheon Group and the Bulguksa igneous rocks during Late Cretaceous time.

Low Power MAC Protocol Design of an Efficient Preamble Exploiting Virtual Synchronization Scheme for Wireless Sensor Networks (무선 센서 네트워크를 위한 효율적인 프리앰블 가상 동기화 기법을 사용하는 저전력 MAC 프로토콜 설계)

  • Lee, Sung-Hun;Hwang, Se-Wook;Lee, Hyuk-Joon;Lee, Hyung-Geun
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.35 no.5B
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    • pp.762-770
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    • 2010
  • The researches about energy efficieny of wireless sensor MAC protocol is an issue in present days. Therefore, MAC and routing protocols for reducing energy consumption at sensor nodes is needed. In this study, a low-power MAC protocol for sensor network is proposed, which in based on X-MAC by exploiting virtual synchronization. The virtual synchronization technique lets senders postpone packet transmission until receivers' wake-up time, so that senders transmit only one or two short preambles. Using NS-2, a proposed MAC protocol improve the energy efficiency by 10% compared with the X-MAC protocol.

Effect of Dietary Intake of Salicornia herbacea L. Hot Water Extract on Anti-obesity in Diet-induced Obese Rats (함초 열수추출물의 섭취가 비만유도 흰쥐의 항비만 효과에 미치는 영향)

  • Lee, Hye-Sung;Choi, Jun-Hyeok;Kim, Youn-Geon;Lee, Chang-Ho
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.41 no.7
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    • pp.950-956
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    • 2012
  • Salicornia herbacea L. is an annual herb that grows in salt marshes and salt fields along the seashores. It is also commonly used as a folk remedy in Korea. The objective of this study was to investigate the beneficial effects of Salicorrnia herbacea L. (SH) hot water extract on obesity. Five-week old male Sprague-Dawley rats (n=36) were divided into two groups and provided either a normal fat diet (11.5% fat from kcal) or a high fat diet (40.5% fat from kcal) for 6 weeks to induce obesity. Then, rats were blocked into six groups of six mice each and provided either a diet containing SH (0.5% of diet; g/kg) or a normal diet for another 6 weeks. Final body weights were significantly reduced when rats were fed SH among the high fat diet groups (HNS and HHS). Serum triglyceride concentrations significantly decreased in every group provided SH. HDL-cholesterol concentrations significantly increased in SH-fed groups among the high fat diet groups. Further, atherogenic index significantly decreased when rats were fed SH diet (HHS). There were no differences in LDL-cholesterol between the high fat diet groups, and glucose concentrations decreased when rats were fed SH diet (HNS). These results indicate that dietary intake of Salicornia herbacea L. hot water extract might have beneficial effects on obesity by reducing body weight, fat weights, and improving blood lipid profile.

Design of a Full-Adder Using Current-Mode Multiple-Valued Logic CMOS Circuits (전류 모드 다치 논리 CMOS 회로를 이용한 전가산기 설계)

  • Lee, Yong-Seop;Gwak, Cheol-Ho;Kim, Jeong-Beom
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.39 no.1
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    • pp.76-82
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    • 2002
  • This paper presents a quaternary-binary decoder, a quaternary logic current buffer, and a quaternary logic full-adder using current-mode multiple-valued logic CMOS circuits. Proposed full-adder requires only 15 MOSFET, 60.5% and 48.3% decrease of devices are achieved compared with conventional binary CMOS full-adder and Current's full-adder. Therefore, decrease of area and internal nods are achieved. Designed circuits are simulated and verified by HSPICE. Proposed full-adder has 1.5 ns of propagation delay and 0.42㎽ of power consumption. Also, proposed full-adder can easily adapted to binary system by use of encoder, designed decoder and designed current buffer.

Scintillating properties of Bi-doped $Y_3Ga_5O_{12}$

  • Novoselov, Andrey;Yoshikawa, Akira;Nikl, Martin;Fukuda, Tsuguo
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.14 no.6
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    • pp.233-235
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    • 2004
  • Shaped single crystals of Bi : $Y_3Ga_5O_{12}$(Bi = 0.041, 0.047 and 0.061 mol%) were grown by the micro-pulling-down method. Optical absorption spectra show an absorption band at 288 nm ascribed to the lowest energy $6s^2$ \longrightarrow 6s6p transition of $Bi^{3+}$ , while luminescence spectra demonstrate the band at 314 nm ascribed to the reverse radiative transition of the excited $Bi^{3+}$ centres. At room temperature, dominant decay time component was found to be about 440 ns with a minor slower component 580 ns.

Low-ripple coarse-fine digital low-dropout regulator without ringing in the transient state

  • Woo, Ki-Chan;Yang, Byung-Do
    • ETRI Journal
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    • v.42 no.5
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    • pp.790-798
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    • 2020
  • Herein, a low-ripple coarse-fine digital low-dropout regulator (D-LDO) without ringing in the transient state is proposed. Conventional D-LDO suffers from a ringing problem when settling the output voltage at a large load transition, which increases the settling time. The proposed D-LDO removes the ringing and reduces the settling time using an auxiliary power stage which adjusts its output current to a load current in the transient state. It also achieves a low output ripple voltage using a comparator with a complete comparison signal. The proposed D-LDO was fabricated using a 65-nm CMOS process with an area of 0.0056 μ㎡. The undershoot and overshoot were 47 mV and 23 mV, respectively, when the load current was changed from 10 mA to 100 mA within an edge time of 20 ns. The settling time decreased from 2.1 ㎲ to 130 ns and the ripple voltage was 3 mV with a quiescent current of 75 ㎂.

Design of a $54{\times}54$-bit Multiplier Based on a Improved Conditional Sum Adder (개선된 조건 합 가산기를 이용한 $54{\times}54$-bit 곱셈기의 설계)

  • Lee, Young-Chul;Song, Min-Kyu
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.37 no.1
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    • pp.67-74
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    • 2000
  • In this paper, a $54{\times}54$-bit multiplier based on a improved conditional sum adder is proposed. To reduce the multiplication time, high compression-rate compressors without Booth's Encoding, and a 108-bit conditional sum adder with separated carry generation block, are developed. Furthermore, a design technique based on pass-transistor logic is utilized for optimize the multiplication time and the power consumption by about 5% compared to that of conventional one. With $0.65{\mu}m$, single-poly, triple-metal CMOS process, its chip size is $6.60{\times}6.69\;mm^2$ and the multiplication time is 135.ns at a 3.3V power supply.

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