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Detection of atypical porcine pestivirus (APPV) from a case of congenital tremor in Korea

포유자돈 선천성 진전증 증례에서 atypical porcine pestivirus (APPV) 검출

  • Kim, Seung-Chai (College of Veterinary Medicine, Chonbuk National University) ;
  • Jeong, Chang-Gi (College of Veterinary Medicine, Chonbuk National University) ;
  • Yoon, Seung-Min (College of Veterinary Medicine, Chonbuk National University) ;
  • Lee, Ki-Ho (College of Veterinary Medicine, Chonbuk National University) ;
  • Yang, Myoun-Sik (College of Veterinary Medicine, Chonbuk National University) ;
  • Kim, Bumseok (College of Veterinary Medicine, Chonbuk National University) ;
  • Lee, Seung-Yoon (HanByol Farm Tech) ;
  • Kang, Seog-Jin (National Institute of Animal Science, Rural Development Administration) ;
  • Kim, Won-Il (College of Veterinary Medicine, Chonbuk National University)
  • Received : 2017.09.11
  • Accepted : 2017.09.28
  • Published : 2017.09.30

Abstract

Congenital tremor (CT) is a sporadic neurodegenerative disease reported in suckling piglets worldwide. Since atypical porcine pestivirus (APPV) was first identified in US in 2015, it has also subsequently detected in Europe and China as a causative pathogen for CT in suckling piglets. Three new-born piglets died from severe tremor was submitted to Chonbuk National University-Veterinary Diagnostic Center (CBNU-VDC) and various tissues (lung, lymph node, brain, intestine) were tested with panpestivirus RT-PCR and APPV NS5B-specific RT-PCR. All of the samples were positive by both of the PCR tests and the partial NS5B sequences of APPV were confirmed by sequencing on the PCR products of APPV NS5B-specific RT-PCR. Therefore, we report the first identification of APPV from a case of CT in suckling piglets in Korea.

Keywords

References

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