• Title/Summary/Keyword: NS5

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Two Pediatric Patients with Herbal Medicine-Induced Nephrotic Syndrome

  • Yang, Sohyoung;Oh, Arum;Ha, Tae-Sun
    • Childhood Kidney Diseases
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    • v.19 no.2
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    • pp.171-175
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    • 2015
  • Nephrotic syndrome (NS) is a common chronic disease in children; in 90 percent of cases, the condition is primary (idiopathic). Toxic nephropathy can be induced by herbal medicines, and is mainly manifested as tubulointerstitial nephritis and rarely, as glomerulopathy. Here in, we describe two cases of steroid-sensitive NS, which developed after the patients received herbal medicines. A 5-year-old boy and an 8-year-old girl were separately admitted within a short time period with acute onset of generalized edema, proteinuria, hypoalbuminemia, and hypercholesterolemia. Each patient had previously taken herbal medicine, which had been prescribed by different oriental medical clinics for different conditions. The patients were diagnosed with herbal medicine-induced NS and were treated empirically by a standard steroid therapy, with subsequent resolution of their NS. One patient relapsed, but her NS again responded to steroid therapy. We described two unusual cases of prototypical pediatric, steroid-sensitive NS, which was presumed to be minimal-change disease that developed after the administration of herbal medicines. We also reviewed the literature.

The Study on the Quality Characteristics of Cake Prepared with Fat Substitute (대체지방으로 제조한 케이크의 품질 특성에 관한 연구)

  • Woo, Na-Ri-Yah;Ahn, Myung-Soo
    • Journal of the Korean Society of Food Culture
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    • v.19 no.5
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    • pp.506-515
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    • 2004
  • This study was carried on the quality characteristics of cake prepared with Co(com oil) containing MCT(medium chain triglycerides), which is used as a fat substitute. In tile cake prepared with MCT-CO containing $10{\sim}30%$ MCT, the appearance and the degree of gelatinization were similar to those of cake prepared with NS-CO(non-substituted corn ell) Cake batter prepared with MCT-CO showed higher specific gravity and consistency than those of cake prepared with NS-CO and increased by increasing MCT contents. The baking loss of cake prepared with MCT-CO was more than that of cake prepared with NS-CO and increased by increasing MCT contents as well. The rheological properties of cake represented significant different by MCT substitution ratio(p<0.05). Gumminess, hardness and chewiness of cake prepared with MCT-CO containing $20{\sim}30%$ MCT were about 2 times higher than those of cake prepared with NS-CO, while springiness and cohesiveness showed similar pattern between the cake prepared with MCT-CO or NS-CO. In sensory evaluation, appearance. color and flavor of cake prepared with CO substituted by MCT up to 100% were better assessed and the taste was better in range of 30% MCT-CO but the texture was less accepted than that of cake prepared with NS-CO.

The Phylogenetic Analysis of the NS-5 Region Sequence of Hepatitis G Viruses Isolated in Korea (국내에서 분리된 G형 간염바이러스 NS-5 Region 염기서열의 계통학적 분석)

  • Jee, Young-Mee;Kim, Ki-Soon;Cheon, Doo-Sung;Park, Jeong-Koo;Kang, Young-Hwa;Lee, Yoon-Sung;Chung, Yoon-Suk;Kim, Ji-Eun;Yoon, Jae-Deuk
    • The Journal of Korean Society of Virology
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    • v.29 no.1
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    • pp.45-53
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    • 1999
  • We examined the hepatitis G virus infections among 227 Koreans who were healthy or were suspected of hepatitis and determined the phylogenetic relationship based on a part of the NS-5 region of 5 positive samples. Viral RNA was extracted from sera and cDNA was synthesized and subsequently amplified by RT-PCR (reverse transcription-polymerase chain reaction) or RT-nested PCR using random hexamer and NS-5 specific primers (470-20-1-77F, 470-20-1-211R, HGVNESTFO, HGVNESTRE). Five positives were found to belong to samples of patients showing symptoms of viral hepatitis. Primers used for PCR or nested PCR were derived from the NS-5 region. On the other hand, no amplification was detected using primers derived from the 5'-NCR (G-146F, G-401R). We performed TA cloning and sequencing of 5 amplified fragments, and their sequences were compared with those of foreign isolates of HGV. The phylogenetic analysis using MegAlign programme of DNAstar has shown that the Korean isolates are clustered on the phylogenetic tree. In summary, we confirmed the hepatitis G virus infection in 5 cases out of 12 patients showing the symptoms of viral hepatitis. The phylogenetic analysis of sequences of 5 amplified fragments showed that their relations to each other were closer than those to the foreign HGV isolates reported.

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Basic study on the biological and physicochemical properties of burnt forest soil for the ecological restoration by organic waste (유기성폐자원을 이용한 산불토양의 생태학적 복원을 위한 토양의 생물학적, 물리화학적 기초특성연구)

  • Jung, Young-Ryul;Song, In-Geun;Kim, Young-Jun
    • Journal of the Korea Organic Resources Recycling Association
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    • v.13 no.1
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    • pp.79-89
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    • 2005
  • Forest soils were analyzed on their biological and physicochemical properties for the ecological restoration of burnt forest soil using organic wastes and proper microorganisms. Three kinds of soil samples were collected from undamaged soil(US), naturally restoring soil(NS) and artificially restoring soil(AS). All soil samples were sandy soil and acidic soil, ranged pH 5.34~5.78. Moisture content was higher in the soil of NS region. And the others were similar. Total organic matter and soluble sugar were higher at the surface, generally. Heterotrophic soil microbes were abundant at the surface soil of NS and subsoil of AS. Dehydrogenase, cellulase and phosphatase activities were higher at the NS soil. Especially, Dehydrogenase activity as primary index of soil microbial process showed high correlationship with moisture content(r=0.90, P < 0.05).

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Channel Modeling and RF Performance Verification in mmWave Bands Based on NS-3 (NS-3 기반의 mmWave 대역 채널 모델링 및 RF 성능 검증)

  • Seung-Min Lee;Jun-Seok Seo;Hong-Je Jang;Myung-Ryul Choi
    • Journal of IKEEE
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    • v.27 no.4
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    • pp.650-656
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    • 2023
  • This paper implements a channel model for mmWave bands using an NS-3-based 5G system-level simulator and analyzes the reliability and validity of the implemented model through RF performance verification. The channel model for RF performance verification in the mmWave bands consider parameters such as characteristics defined in 3GPP TR 38.901, beam-forming, antenna configuration, scenarios, among others. Furthermore, the simulation results verify compliance within the ranges permitted by the 3GPP standards and verify reliability in indoor environmental scenarios by exploiting the Radio Environment Map (REM). Therefore, the channel model implemented in this study is applicable to the actual design and establishment of 5G networks, presenting a method to evaluate and validate RF performance by adjusting various parameters.

Performance Evaluation of Turbo coded Adaptive QAM Systems for High-speed Mobile Multimedia Communications (고속 이동 멀티미디어 통신을 위한 터보 부호 적응 QAM 시스템의 성능 분석)

  • 백흥현;정연호
    • Journal of the Institute of Convergence Signal Processing
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    • v.5 no.3
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    • pp.216-222
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    • 2004
  • Frequency selective fading is a limiting factor for transmission rate and performance in high-speed multimedia communications. In this paper, we propose a turbo coded adaptive quadrature amplitude modulation (QAM) system for efficient high-speed transmission. By making use of a user-friendly simulation platform of SPW, the proposed turbo coded adaptive QAM system(TuAQAM) is developed and its performance is evaluated in terms of throughput and BER performance. Two channel models having delay spreads of 700ns and 1400ns are created for the simulations. It is shown that the proposed TuAQAM system provides a performance improvement of approximately 3dB and improved throughput for the channel model whose delay spread is 700ns. Similarly, a performance improvement is also achieved for the channel model whose delay spread is 1400ns.

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Genome analysis of Yucatan miniature pigs to assess their potential as biomedical model animals

  • Kwon, Dae-Jin;Lee, Yeong-Sup;Shin, Donghyun;Won, Kyeong-Hye;Song, Ki-Duk
    • Asian-Australasian Journal of Animal Sciences
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    • v.32 no.2
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    • pp.290-296
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    • 2019
  • Objective: Pigs share many physiological, anatomical and genomic similarities with humans, which make them suitable models for biomedical researches. Understanding the genetic status of Yucatan miniature pigs (YMPs) and their association with human diseases will help to assess their potential as biomedical model animals. This study was performed to identify non-synonymous single nucleotide polymorphisms (nsSNPs) in selective sweep regions of the genome of YMPs and present the genetic nsSNP distributions that are potentially associated with disease occurrence in humans. Methods: nsSNPs in whole genome resequencing data from 12 YMPs were identified and annotated to predict their possible effects on protein function. Sorting intolerant from tolerant (SIFT) and polymorphism phenotyping v2 analyses were used, and gene ontology (GO) network and Kyoto encyclopedia of genes and genomes (KEGG) pathway analyses were performed. Results: The results showed that 8,462 genes, encompassing 72,067 nsSNPs were identified, and 118 nsSNPs in 46 genes were predicted as deleterious. GO network analysis classified 13 genes into 5 GO terms (p<0.05) that were associated with kidney development and metabolic processes. Seven genes encompassing nsSNPs were classified into the term associated with Alzheimer's disease by referencing the genetic association database. The KEGG pathway analysis identified only one significantly enriched pathway (p<0.05), hsa04080: Neuroactive ligand-receptor interaction, among the transcripts. Conclusion: The number of deleterious nsSNPs in YMPs was identified and then these variants-containing genes in YMPs data were adopted as the putative human diseases-related genes. The results revealed that many genes encompassing nsSNPs in YMPs were related to the various human genes which are potentially associated with kidney development and metabolic processes as well as human disease occurrence.

Recognizing F5-like stego images from multi-class JPEG stego images

  • Lu, Jicang;Liu, Fenlin;Luo, Xiangyang
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.8 no.11
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    • pp.4153-4169
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    • 2014
  • To recognize F5-like (such as F5 and nsF5) steganographic algorithm from multi-class stego images, a recognition algorithm based on the identifiable statistical feature (IDSF) of F5-like steganography is proposed in this paper. First, this paper analyzes the special modification ways of F5-like steganography to image data, as well as the special changes of statistical properties of image data caused by the modifications. And then, by constructing appropriate feature extraction sources, the IDSF of F5-like steganography distinguished from others is extracted. Lastly, based on the extracted IDSFs and combined with the training of SVM (Support Vector Machine) classifier, a recognition algorithm is presented to recognize F5-like stego images from images set consisting of a large number of multi-class stego images. A series of experimental results based on the detection of five types of typical JPEG steganography (namely F5, nsF5, JSteg, Steghide and Outguess) indicate that, the proposed algorithm can distinguish F5-like stego images reliably from multi-class stego images generated by the steganography mentioned above. Furthermore, even if the types of some detected stego images are unknown, the proposed algorithm can still recognize F5-like stego images correctly with high accuracy.

Effects of Nitrogen Fertilization on Physiological Characteristics and Growth of Populus sibirica Seedlings in a Semi-arid Area, Mongolia (몽골 반건조지에서의 질소 시비가 Populus sibirica 묘목의 생리 및 생장 특성에 미치는 영향)

  • Chang, Hanna;Han, Seung Hyun;Kang, Hoduck;Akhmadi, Khaulenbek;Son, Yowhan
    • Journal of Korean Society of Forest Science
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    • v.106 no.1
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    • pp.19-25
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    • 2017
  • This study was conducted to investigate the effects of nitrogen fertilization on physiological characteristics and growth of Populus sibirica seedlings in a semi-arid area, Mongolia. 2-year-old P. sibirica seedlings were planted in May, 2015 with applications of urea 5 g (N1), 15 g (N2), 30 g (N3) and ammonium sulfate 33 g (NS; same nitrogen amount with N2) to each seedling. Chlorophyll contents were significantly different among treatments in August, but not in June and July. The lower chlorophyll contents in August than those in June and July might be related to leaf senescence. In June and July, net photosynthetic rate was higher in NS and N2 than in the control. Unlike the tendency of photosynthesis, transpiration rate was highest in N2, but lower in NS than in any other nitrogen treatments. Relative growth rate of root collar diameter was significantly higher only in NS than in the control and it of height did not differ among treatments. Leaf area in nitrogen treatments was not significantly different from that in the control. Ammonium sulfate seemed to be more suitable fertilizer than urea for the early growth of P. sibirica seedlings in the study site. However, as the effects of urea and ammonium sulfate on soils and seedlings were different, further studies would be necessary to determine the optimal amount of ammonium sulfate.

Studies on the Quality of Processing Potatoes grown at Different Locations (裁培地域에 따른 加工用 감자의 品質에 關한 硏究)

  • 양성지
    • Korean Journal of Plant Resources
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    • v.10 no.1
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    • pp.30-38
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    • 1997
  • Influence of different cultivated areas on the processing-grade tuber yield, specific gravity, reducing sugar content and tuber qualities of five promising varieties was studied to get the basic information for selecting potato varieties with good processing quality under the different cultivated conditions on Korea. The average total tuber yields of 5 tested varieties at the 2nd harvest time was 3,.051kg/10a in Daekwallyoung. The processing-grade tuber yield of the late-maturing variety of Gemchip was over 3.2 tons per 10a, whereas that of late-maturing variety, NS1 was 2.8 tons per 10a. The dry matter content of the tubers produced from Daekwallyoung was the highest, followed by the order of Bosung, atlantic was the highest in dry matter content, followed by the order of NS1, NS2, Superior and Gemchip. Degrees of change in glucose content as affected by change of cultivated areas were different among varieties. Atlantic and NS1 showed less change of glucose content as compared with other varieties.

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