• Journal of the Society of Naval Architects of Korea
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• v.38 no.2
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• pp.71-78
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• 2001

In ship building industry, CNC and CAM are mostly applied to NC cutting and manufacturing of propeller and prototype ship model. Herein, prototype ship model is producted by CAD/CAM process. Hull form data is obtained from the ship drawing and used for 3D modeling by CAD software Pro/Engineer. CAD data is transferred into CAM s/w SPEEDplus to perform CNC process and the prototype small ship model is manufactured by CNC machine. To solve data transfer among different systems. IGES and STEP neutral formats are currently used. Herein IGES format is adopted for data transfer between CAD/CAM softwares.

• Korean Journal of Applied Biomechanics
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• v.15 no.2
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• pp.103-111
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• 2005

The purpose of this study was to analysis golf swing in accordance with each club using ground reaction force data. The subject of this study was current professional golf players in Korea. Golf clubs used for this study were driver, iron4, iron7, and pitching. The ground reaction force for left and right foot was collected by one Kistler and one Bertec force platforms. Also collected visual data by NC high speed camera to check the phase which was composed of address, top of backswing, impact and finish. Sampling rate was 600Hz both ground reaction forces data and visual data. The conclusion are as follows. 1. An aspect of change for ground reaction force was that the weight between the left foot and right foot were contrary to each other in general as the phase. 2. Without regard to the type of golf club, the ratio of necessary ground reaction forces for each phase in accordance with address, top of backswing, impact, and finish was comparatively identical. 3. According to the type of golf club, the tendency of Fy was not varied. In terms of Driver, at the moment of impact, the weight of foot-both right and left-was moved to the movement direction of golf because of the rotation force from swing.

• Journal of Korean Institute of Industrial Engineers
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• v.41 no.3
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• pp.253-258
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• 2015

The 3D printing is any of various processes for making a three dimensional object of almost any shape from a 3D model. Recently, a rapidly expanding hobbyist and home-use market has become established with the inauguration of the open-source RepRap and Fab@Home projects. However, this causes problems regarding copyright protection and usage of illegal 3D data. In this paper, we developed a 3D printing open-market system, which guarantees copyright protection using the remote 3D printing without direct distribution of 3D design data. Because most of the home-use 3D printers are FFF (Fused Filament Fabrication) based on NC code system, open-market system uses FFF 3D printers. Also, open-market system inspects the uploaded 3D model data, so the system can prevent distribution of illegal model data such as weapons, etc.

• The Journal of Advanced Prosthodontics
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• v.9 no.3
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• pp.176-181
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• 2017

PURPOSE. The purpose of this study was to evaluate the marginal and internal gaps of Ni-Cr and Co-Cr copings, fabricated using the dental ${\mu}-SLA$ system. MATERIALS AND METHODS. Ten study dies were made using a two-step silicone impression with a dental stone (type IV) from the master die of a tooth. Ni-Cr (NC group) and Co-Cr (CC group) alloy copings were designed using a dental scanner, CAD software, resin coping, and casting process. In addition, 10 Ni-Cr alloy copings were manufactured using the lost-wax technique (LW group). The marginal and internal gaps in the 3 groups were measured using a digital microscope ($160{\times}$) with the silicone replica technique, and the obtained data were analyzed using the non-parametric Kruskal-Wallis H test. Post-hoc comparisons were performed using Bonferroni-corrected Mann-Whitney U tests (${\alpha}=.05$). RESULTS. The mean (${\pm}$ standard deviation) values of the marginal, chamfer, axial wall, and occlusal gaps in the 3 groups were as follows: $81.5{\pm}73.8$, $98.1{\pm}76.1$, $87.1{\pm}44.8$, and $146.8{\pm}78.7{\mu}m$ in the LW group; $76.8{\pm}48.0$, $141.7{\pm}57.1$, $80.7{\pm}47.5$, and $194.69{\pm}63.8{\mu}m$ in the NC group; and $124.2{\pm}52.0$, $199.5{\pm}71.0$, $67.1{\pm}37.6$, and $244.5{\pm}58.9{\mu}m$ in the CC group. CONCLUSION. The marginal gap in the LW and NC groups were clinically acceptable. Further improvement is needed for CC group to be used clinical practice.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.2
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• pp.483-496
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• 2018

NCS (National Competency Standards) has emerged as an issue of great importance amongst Korean universities and corporations. Although previously used mostly for vocational education purposes at colleges, NCS is currently receiving an increasing amount of attention from 4-year universities as well. In the ever-evolving information economy, the basic workplace skills defined by NCS, which include soft skills such as communication skills, problem-solving skills, and interpersonal skills, have now become more important than specific technical skills. This study analyzes the correlation between the basic workplace skills of NCS with participation in Formula SAE activities, a common component of Capstone design courses across North America and Europe. Data are derived from site visits to Formula SAE competitions, competition-related documents drafted by student participants, and questionnaires administered to student participants at the Formula SAE Lincoln completion and at the Korea KSAE competition. From the study findings, we claim that the basic workplace skills of NCS are closely correlated to participation in Formula SAE activities. Through a survey designed to measure the degree to which Formula SAE activities can enhance an individual's NCS Basic Workplace Skills, we find that these activities overall improved NCS basic workplace skills averaging 4.0 points above in the Likert 5-point scale. For reference the mathematical skills, communication skills, and problem-solving skills displayed statistically significantly correlation with NCS but the remaining 7 skills did not show a statistically strong correlation with NCS comparatively.

• Journal of Life Science
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• v.28 no.11
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• pp.1321-1331
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• 2018

The aim of this study was to separate the photosensitizer that induces apoptosis of U937 and SK-HEP-1 cells from Nostoc commune. Dried N. commune was extracted with $CH_2Cl_2/MeOH$ (1:1) to separate the photosensitizer using various chromatographic techniques. The isolated compound was identified as pheophytin a ($C_{55}H_{74}N_4O_5$) with a molecular weight of 870. Its photodynamic activities were assessed under different irradiation conditions (light and non-light) at the same concentration range of $1.15-23.0{\mu}M$. The apoptosis inducing activity in U937 or SK-HEP-1 cells appeared only in the light. The mechanisms underlying the pheophytin a-mediated photodynamic inhibition of cancer cells were further investigated by examining cell morphology changes, cytotoxicity, caspase-3/7 activity, fluorescence staining, flow cytometry analysis, and DNA fragmentation in these two cell lines. The positive control and the light irradiation group showed typical apoptotic responses, including morphological changes, cytotoxicity, caspase activity, nucleus shrinkage owing to chromatin condensation, DNA laddering, and the presence of apoptotic bodies. Cytotoxicity markedly increased in a dose-dependent manner after a 12 hr exposure. Caspase-3/7 activity was higher in U937 cells than in SK-HEP-1 cells. Apoptosis induction therefore appeared to be both concentration- and light-dependent. In conclusion, pheophytin a, isolated from the blue green alga N. commune, had a photodynamic apoptosis-inducing effect on U937 and SK-HEP-1 cells. The findings reported here can be used as basic data for the development of next-generation photosensitizers from N. commune.

• Journal of the korean academy of Pediatric Dentistry
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• v.46 no.2
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• pp.226-232
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• 2019

The purpose of this study was to investigate the effect of adding a protective coating on the microhardness and wear resistance of glass ionomer cements (GICs). Specimens were prepared from GIC and resin-modified GIC (RMGI), and divided into 3 groups based on surface protection: (1) no coating (NC), (2) Equia coat coating (EC), and (3) un-filled adhesive coating (AD). All specimens were then placed in distilled water for 24 h. Surface hardness (n = 10) was evaluated on a Vickers hardness testing machine. Wear resistance (n = 10) was evaluated after subjecting the specimen to thermocycling for 10,000 cycles using a chewing simulator. Data were analyzed using a one-way ANOVA and the Kruskal-Wallis test. Surface hardness was highest in the NC groups, followed by the EC and AD groups. The wear depth of GI + NC was significantly higher than that of all RMGI groups. EC did not significantly lower the wear depth compared to AD. Based on these results, it was concluded that although EC does not increase the surface microhardness of GIC, it can increase the wear resistance.

• Journal of Korea Game Society
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• v.12 no.3
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• pp.3-10
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• 2012

Social network game induces to continue participation among the players through asynchronous connection mode. This characteristic of SNG that is required active social connectedness and that is the main purpose of SNG. The player's behavior attributes related with social connectedness can be divided by the environmental conception. In this paper, the player's behavior is divided into two types : Social Connectedness(SC) and Non-Social Connectedness(NC). Each type is categorized in specific actions of players that is explored. Also, experimental data collected from player's playing-game is analyzed in the comparison of each behavior and the relation of playfulness. Those results have suggested the scope for designing a appliable model on SNG development and represented the guideline to verify speedy the massive player's behavior through simplifying the player's behavior derived in SNG play experiences.

• Journal of Haehwa Medicine
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• v.18 no.2
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• pp.63-79
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• 2009

Atopic dermatitis induced NC/Nga mice were used to investigate the efficacy of Hyunggaeyunkyotanggamibang(HYGB) on the recovery of dermatitic symptoms through its influence on the immune related factors. The results are as below: 1. HYGB treated group showed improvement of atopic dermatitis with naked eye observation, and significant decrease of dermatitis index was observed after 14 weeks. 2. HYGB treated group showed significant decrease of the ratio of CCR3+, B220+/IgE+, and CD11b+/Gr-1+ immune cells in dorsal skin by 41.7%, 21.5%, and 23.8%, respectively. 3. HYGB treated group showed an increase of CD19+ immune cells by 10.3% in PBMC, whereas CD3+, CD3+/CD69+, NKT+ immune cells were decreased by 4.3%, 42.9%, and 21.7%, respectively. 4. HYGB treated group showed an increase in the expression of IFN-$\gamma$ in the serum by 514.3%. However, the expressions of IL-4, IL-5, IL-6, IL-13, TNF-$\alpha$, MCP-1 and RANTES were decreased by 21.2%, 69.8%, 90.5%, 28.7%, 72.2%, 26.1%, and 19.9%, respectively. Also, the expression of IgE was decreased by 44.3%. 5. HYGB treated group showed a decrease of the expression of IL-4 and IL-5 by 43% and 44.3%. The results above indicated that HYGB clinically used for atopic dermatitis treatment has objective validity, and therefore can be provided as the basic data for EBM(Evidence based medicine) construction for anti-allergic and anti-inflammatory studies.

• The Journal of the Korea Contents Association
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• v.13 no.8
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• pp.466-473
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• 2013

Gene expression is regulated by a wide range of mechanisms at the DNA sequence level. In addition, gene expression is also regulated by epigenetic mechanisms through DNA methylation, histone modification, and ncRNA. To understand the regulation of gene expression at the epigenetic level, we constructed aging related gene database and analyzed epigenetic properties that are focused on DNA methylation. The DNA methylation of promoter or upstream region of the genes induces to repress the gene expression. We compared and analyzed distribution between whole human genes and aging related genes in the epigenetic properties such as CGI distribution, methylation motif pattern, and TFBS (transcription factor binding site) distribution. In contrast to methylation motif pattern, CGI and TFBS distributions are positively correlated with epigenetic regulation of aging related gene expression. In this study, the epigenetic data about DNA methylation of the aging genes will provide us to understand phenomena of the aging and epigenetic mechanism for regulation of aging related genes.