• Title/Summary/Keyword: NC-Data

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Acceleration of DNCB-induced Early-apoptosis via Activation of Corticotropin Releasing Factor in the Hair Root of NC/Nga Mice (DNCB로 유도된 NC/Nga 아토피피부염마우스에서 부신피질자극호르몬방출인자 활성에 따른 모발세포의 초기세포사멸 연구)

  • Park, Gunhyuk;Jang, Eunyoung;Kim, Seongbae;Han, Eunyoung;Kim, Yong-ung
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.43 no.4
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    • pp.281-287
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    • 2017
  • Stress in skin plays a significant role in both the direct/indirect regulation of cellular processes occurring in hair, which in turn affect the hair cycle. However, experimental data regarding the effects of stress-related corticotropin releasing factor (CRF) released by stress on the apoptotic process involved in hair is limited. Therefore, we investigated the acceleration of early-stage apoptosis induced by atopy-related stress using a 2,4-dinitrochlorobenzene NC/Nga mice model. Expression of CRF, its related proteins, annexin V, and mitochondrial dysfunction were measured by immunohistochemical analyses. Atopic stress strongly stimulated stress hormones response, such as CRF and adrenocorticotropic hormone, in outer epithelial sheath of the hair. Moreover, its stress induced mitochondrial damage and early-stage apoptosis of cells in hair root. These findings suggest that hair damage due to apoptosis in atopy model is accelerated in a high CRF environment. Importantly, the effect of stress-related CRF on apoptosis processes involved in atopy dermatitis-related hair loss, suggests that the CRF-regulating development or maintenance materials may provide effective therapeutic strategies for hair health.

Hydraulic Characteristics of Busan Clay in the Floodplain of the Nakdong River Delta (낙동강 삼각주 범람원에서 부산점토의 수리학적 특성)

  • Chung, Seong-Gyo;Lee, Nam-Ki;Lee, Jeong-Man;Min, Se-Chan;Hong, Yang-Pyo
    • Journal of the Korean Geotechnical Society
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    • v.26 no.11
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    • pp.47-61
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    • 2010
  • To predict the settlement rate of a ground area that incorporates vertical drains, it is desirable to conduct various kinds of advanced field and laboratory tests for hydraulic properties. However, it is urgently needed to appropriately evaluate the hydraulic properties using the results of conventional soil tests which are extensively used for local practice. To achieve this purpose, a number of CPT dissipation test, laboratory permeability and consolidation tests were performed at five sites in the floodplain of the Nakdong River delta, and the test data were comprehensively analyzed. As a result, it is found that the coefficients of horizontal consolidation ($C_{h,NC}$) and permeability ($k_{h,OC}$) of the clay agreed well with those of the CPT-based methods proposed by Baligh and Levadoux (1986). The values of $C_{h,NC}$ and $k_{h,OC}$ were in the range of $0.4{\sim}3.0\;cm^2/sec$ and $0.40{\sim}2.50\;cm^2/sec$, each of which slightly increases or decreases with depth, respectively. It was also inferred that these trends seem to reflect the depositional environments of the clay.

Approximation of a compound surface to polyhedral model (복합곡면의 다면체 곡면 근사)

  • 김영일;전차수;조규갑
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 1996.04a
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    • pp.100-103
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    • 1996
  • Presented in this study is an algorithmic procedure to obtain polyhedral model from a compound surface. The compound surface in this study denotes a collection of trimmed surfaces without topological relations. The procedure consists of two main modules: CAD data interface, and surface conversion to polyhedral model. The interface module gets geometric information from CAD databases, and makes topological information by scanning the geometric information. We are investigating CATIA system as a data source system. In the surface conversion module, a shell(compound surface with topological information) is approximated to a triangular-faceted polyhedral surface model through node sampling and triangulation steps. The obtained polyhedral model should obey the vertex-to-vertex rule and meet tolerance requirements. Since the polyhedral model has a simple data structure and geometry processing for it is very efficient and robust, the polyhedral model can be used in various applications, such as surface rendering in computer graphics, FEM model for engineering analysis, CAPP for surface machining, data generation for SLA, and NC tool path generation.

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Analysis of Human Head Shapes in the United States

  • Lee, Jin-Hee;Hwang Shin, Su-Jeong;Istook, Cynthia L.
    • International Journal of Human Ecology
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    • v.7 no.1
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    • pp.77-83
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    • 2006
  • The ability to customize garments for fit in the apparel industry is directly tied to the availability of comprehensive and accurate sets of anthropometrical data for each consumer. The data for apparel sizing systems is available from three major standard/ research organizations: ASTM (American Society for Testing and Materials), ISO (International Standard Organization), and NCHS (National Center for Health Statistics). However, these standards ignore various head shapes and are outdated for the development future head products. This creates a data gap an ever changing multi-cultural society such as the United Sates. Although major government and industry safety organizations recognize the importance of safety for head products, few studies were found to support their reasoning. The purpose of this study is to provide accurate head dimension data for developing safety head products by analyzing various head shapes in the United Sates which includes various ethnic backgrounds. This study was carried out on 105 males in the United States. Factor analysis, cluster analysis, Moreover, Duncan analysis were all used for analyzing various head shapes.

Development of a 3D Shape Construction Software Using Unorganized Point Data (점 데이터를 이용한 3차원 형상의 구현을 위한 소프트웨어 개발)

  • 채희창
    • Transactions of the Korean Society of Machine Tool Engineers
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    • v.11 no.1
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    • pp.1-9
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    • 2002
  • Reverse engineering is an emerging technology to obtain CAD models from existing physical parts in the case that CAD models are not available or paras are changed an(1 modified so that new CAD models for final parts are necessary. Reverse engineering helps designers to quickly generate computer interpretable data from existing Physical objects So it is applying for field of Rapid Prototyping NC Processing CAE, Inspection and so on. The objective of this study is to develop the software that deals with unorganized point data and quickly obtains CAD model. In this paper, several models such as human\`s bone, car, are experimented by the proposed methods.

A Study on the COntour Machining of Text using CNC Laser Machine (CNC레이저 가공기를 이용한 활자체 가공에 관한 연구)

  • 구영회
    • Proceedings of the Korean Society of Machine Tool Engineers Conference
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    • 1999.10a
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    • pp.554-559
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    • 1999
  • The purpose of this study is the machining of texture shapes by the contour fitting data. The hardware of the system comprises PC and scanning system, CO2 laser machine. There are four steps, (1) text image loading using scanning shapes or 2D image files, (2) generation of contour fitting data by the line and arc, cubic Bezier curve, (3) generation of NC code from the contouring fitting data, (4) machining by the DNC system. It is developed a software package, with which can conduct a micro CAM system of CNC laser machine in the PC without economical burden.

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Determination of Tool Orientation in 5-Axis Milling Using Potential Energy Method (포텐셜 에너지를 이용한 5축 NC 밀링의 공구방향 결정)

  • Cho, Inhaeng;Lee, Kunwoo
    • Journal of the Korean Society for Precision Engineering
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    • v.13 no.6
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    • pp.161-167
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    • 1996
  • In five-axis milling, optimal CL-data (cutter location data) should be generated to have advantages over three-axis milling in terms of accuracy and efficiency. This paper presents an algorithm for generating collision-free CL-data for five-axis milling using potential energy method. By virtually charging the cutter and part surfaces with static electricity, global collision as wells as local interference is eliminated. Additionally, machining efficiency is improved by minimizing the curvature difference between the part surface and tool swept surface at a CC-point (cutter contact point) simultaneously.

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Development of An User-Friendly Integrated Program and Teaching System for Automatic Polishing Robot System (자동 연마 시스템의 사용자 지향형 통합 프로그램 및 자동 교시 시스템 개발)

  • Go, Seok-Jo;Lee, Min-Cheol;Lee, Man-Hyeong;An, Jung-Hwan;Jeon, Cha-Su;Lee, Don-Jin
    • Journal of Institute of Control, Robotics and Systems
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    • v.7 no.4
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    • pp.334-343
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    • 2001
  • Polishing a die that has free-form surfaces is a time-consuming and tedious job, and requires a considerable amount of high-precision skill. Some workers tend to gradually avoid the polishing work because of the poor environment caused by dust and noise. In order to reduce the polishing time and cope with the shortage of skilled workers, a user-friendly automatic polishing system was developed in this research. The polishing system with five degrees of freedom is able to keep the polishing tool normal to the die surface. The polishing system is controlled by a PC-NC controller. To easily operate the developed polishing robot system, this study developed an integrated program in the Windows environment. This program consists of four modules: the polishing module, the graphic simulator, the polishing data generation module, and the teaching module. Also, the automatic teaching system was developed to easily obtain teaching data and it consists of a three dimensional joystick and a proximity sensor. The joystick is used to simultaneously drive the polishing system to an arbitrary orientation and the proximity sensor is used to obtain teaching points precisely. Also, to evaluate the stability of the driving program and the teaching system, polishing experiments of a die of saddle shape were carried out.

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Electronic Catalogue Based Cutting Parameter Selection (전자 카탈로그식 절삭변수 선정의 자동화)

  • 이성열
    • Journal of Korea Society of Industrial Information Systems
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    • v.6 no.4
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    • pp.1-5
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    • 2001
  • This study presents an electronic catalogue based cutting parameter selection system using MS Access software. The proposed system has been designed to electronically select proper cutting conditions based on the stored data base. The existing approaches used in most small and medium sized companies are basically to use manufacturing engineer's experience or to find the recommended values from the manufacturing engineer handbook. These processes are often time consuming and inconsistent, especially when a new engineer is involved. Therefore, this study proposes a simple, yet quick and consistent electronic catalogue based cutting parameter selection method which uses MS Access in terms of programming and database implementation. Consequently, the proposed system could automatically generate the proper cutting conditions (feed, depth of cut, and cutting speed) as soon as the input data (proper information about the tool and work material) is given. Thanks to the simple structure and popularity of the MS Access, the engineer could be quickly accustomed to the system and easily modify/insert/delete the database if necessary.

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Influencing Factors of the Organizational Commitment among Hospital Nurses (병원간호사의 조직몰입에 영향을 미치는 요인)

  • Lee, Keum Jae;Lee, Eliza;Choi, Shim Young
    • Korean Journal of Occupational Health Nursing
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    • v.22 no.1
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    • pp.35-46
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    • 2013
  • Purpose: The study aimed to identify influencing factors associated with the organizational commitment (OC) among hospital nurses. Methods: A descriptive correlational design was utilized. The subjects of this study were 447 female nurses working for over 6 months in Seoul. The study was based on the data from a self-reported survey using structured questionnaires. The data were collected from September 10 to 30, 2009 and analyzed using Pearson's correlation coefficients and stepwise multiple regression analysis. Results: The mean score of the OC was 2.45, slightly higher than the intermediate level. The mean score of the three-dimensional domain among the OC, affective commitment (AC) was 2.50, continuance commitment (CC) was 2.59, and normative commitment (NC) was 2.29. The influencing factors of nurses' AC were perceived organizational support (POS) (${\beta}$=.31, p<.001), supervisory trust, job burnout, nursing professionalism, and age, which accounted for 49.7%. The influencing factors of the CC were supervisory trust (${\beta}$=.20, p<.001), POS, and job burnout whereas the influencing factors of the NC were POS (${\beta}$=.40, p<.001), supervisory trust, nursing professionalism, and job burnout. Conclusion: It is necessary to develop supportive strategies that increase OC, which also improve the POS, nursing professionalism, and supervisory trust, and alleviate job burnout in hospital nurses.