• 제목/요약/키워드: N limitation

검색결과 437건 처리시간 0.032초

Methylomonas mnosa에 의한 Exopolysaccharide의 유가식 및 연속 생산 (Exopolysaccharide Production in Fed-batch and Continuous Culture by Methylomonas mucosa)

  • 장호남;권선훈심상준
    • KSBB Journal
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    • 제8권2호
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    • pp.164-171
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    • 1993
  • Methylomonas mucosa를 이용하여 세포외 다당류의 생산을 알아보았다. 본 미생물은 성장을 위해 메탄올을 탄소원으로 이용하여 세포외 다당류를 생산한다. 효과적인 발효 공정 시스템의 개발올 위해 회 분식, 유가식, 연속식 배양을 수행하여 각각의 당류 에 대한 생산성을 알아보았다. 플라스크 배양에서 메탄올이 약 1 % (v/v) 이상에서 다당류의 생산과 세포의 성장은 저해되었다. 1% (v/v)에서 최대 비성장속도를 나타내었고 C/N 비율이 높을수록 다당류의 생산은 많았다. 다당류의 생산에 $Mg^{2+}$ 이온 농도가 크게 영향을 줌을 확인할 수있었다. 유가식 배양에서는 다당류의 농도가 회분식에 비 해 4배 이상 높았으나 수율은 오히려 감소하였다. 연속주입을 통한 유가식 배양은 간헐적 주업방법보다 생산성이 높았다. 이는 간헐적 주입에서 나타날 수 있는 메탄올에 의한 제한이나 저해가 없었기 때 문으로 보여진다. 연속조엽은 산소 제한을 피하기 위해 순수산소를 공급하였다. 희석률이 O.21h-1까지 증가하여도 수융 과 생산성은 증가하였다. 생산된 다당류 용액의 점도는 다당류의 증가에 따라 지수적으로 증가하였다.

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3차원 요부안정화 운동이 20대 요통환자의 통증과 동적 및 정적 균형능력 향상에 미치는 효과 (The Effects of 3-Dimensional Lumbar Stabilization Exercise have an effect on the improvement of pain and static or dynamic balance ability in 20's age group with Low Back Pain)

  • 김규용;안창식;김성수
    • 대한물리의학회지
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    • 제6권2호
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    • pp.235-246
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    • 2011
  • Purpose: The aim of this study is to compare and assess the effects of lumbar stabilization exercise on the balance ability of young college studets with low back pain after having performed spinal stabilization exercise by using 3-dimensional air-balance system and gym ball. Methods: The subjects of this study were 34 low back patients in their early twenties. They were divided into two groups: 3-dimensional lumbar stabilization exercise group(N=17) and gym ball lumbar stabilization exercise group(N=17). The period of the intervention was for five weeks. VAS(Visual Analogue Scale) for pain test, ODI(Oswestry Disability Index) for ADL limitation test, Tetrax system for static balance test, and Air-balance system 3D for dynamic balance test were used as evaluation tools for this study. Results: Pain showed significant decrease in both groups after having performed the experiment, but ADL limitation of the groups did not show any remarkable difference between before and after the experiment. Dynamic balance ability in the 8-directional angle comparison test significantly increased in all directions except for the backward, left-backward, and right-backward directions. As for dynamic balance ability in the 8-directional postural test, 3D exercise group showed statistically significant reduction in every direction while gym ball exercise group did not(p<.05). However, when it comes to static balance ability in the weight distribution and stability test, there was not significantly change between pre and post test in both groups. Conclusion: This study shows 3-dimensional lumbar stabilization exercise is more effective in the lumbar stabilization of coordinated movement than gym ball exercise, which may imply that 3D air-balance system can be used for the therapeutic treatment of body imbalance for patients with low back pain.

Integration of WFST Language Model in Pre-trained Korean E2E ASR Model

  • Junseok Oh;Eunsoo Cho;Ji-Hwan Kim
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제18권6호
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    • pp.1692-1705
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    • 2024
  • In this paper, we present a method that integrates a Grammar Transducer as an external language model to enhance the accuracy of the pre-trained Korean End-to-end (E2E) Automatic Speech Recognition (ASR) model. The E2E ASR model utilizes the Connectionist Temporal Classification (CTC) loss function to derive hypothesis sentences from input audio. However, this method reveals a limitation inherent in the CTC approach, as it fails to capture language information from transcript data directly. To overcome this limitation, we propose a fusion approach that combines a clause-level n-gram language model, transformed into a Weighted Finite-State Transducer (WFST), with the E2E ASR model. This approach enhances the model's accuracy and allows for domain adaptation using just additional text data, avoiding the need for further intensive training of the extensive pre-trained ASR model. This is particularly advantageous for Korean, characterized as a low-resource language, which confronts a significant challenge due to limited resources of speech data and available ASR models. Initially, we validate the efficacy of training the n-gram model at the clause-level by contrasting its inference accuracy with that of the E2E ASR model when merged with language models trained on smaller lexical units. We then demonstrate that our approach achieves enhanced domain adaptation accuracy compared to Shallow Fusion, a previously devised method for merging an external language model with an E2E ASR model without necessitating additional training.

저전압 저전력 CMOS복합 트랜스컨덕터 설계 (Design of A CMOS Composite Transconductor for Low-voltage Low-power)

  • 이근호
    • 대한전자공학회논문지SD
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    • 제39권10호
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    • pp.65-73
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    • 2002
  • 두 가지 방식을 이용하여 넓은 동작 영역을 갖는 복합 트랜지스터를 제안하고, 이를 이용하여 새로운 트랜스컨덕터를 설계하였다. 저전압 저전력 특성을 위해 첫 번째 제안한 복합 트랜지스터 I은 P형 폴디드(P-type folded) 복합 트랜지스터를 이용하였으며, 복합 트랜지스터Ⅱ는 복합 다이오드 방식을 이용하여 문턱전압을 감소하였다. 이와 더불어 제안된 트랜지스터가 전류원에 의해 동작 영역이 제한되는 원인을 고찰하였으며, 응용 회로로 설계된 트랜스컨덕터의 특성을 해석하였다. 설계된 회로는 0.2㎛ CMOS n-well 공정 파라미터를 이용하여 HSPICE 시뮬레이션 하였다.

Estimation of Antenna Correlation Coefficient of N-Port Lossy MIMO Array

  • Saputro, Susilo Ady;Nandiwardhana, Satya;Chung, Jae-Young
    • ETRI Journal
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    • 제40권3호
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    • pp.303-308
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    • 2018
  • This paper proposes a simple yet accurate method for estimating the antenna correlation coefficient (ACC) of a high-order multiple-input multiple-output (MIMO) antenna. The conventional method employed to obtain the ACC from three-dimensional radiation patterns is costly and difficult to measure. An alternate method is to use the S-parameters, which can be easily measured using a network analyzer. However, this method assumes that the antennas are highly efficient, and it is therefore not suitable for lossy MIMO antenna arrays. To overcome this limitation, we define and utilize the non-coupled radiation efficiency in the S-parameter-based ACC formula. The accuracy of the proposed method is verified by the simulation results of a 4-port highly coupled lossy MIMO array. Further, the proposed method can be applied to N-port arrays by expanding the calculation matrix.

휴대용 연료전지를 위한 부탄 자열개질에 관한 연구 (Study on n-Butane Autothermal Reforming for Portable Fuel Cell)

  • 배규종;강인용;임성광;배중면;김주용;이찬호
    • 대한기계학회논문집B
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    • 제30권11호
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    • pp.1123-1130
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    • 2006
  • This study discusses about research efforts of hydrogen generation from hydrocarbon(e.g., diesel, gasoline, natural gas, and LPG), especially, butane reforming by using Autothermal Reforming Reaction (ATR) technology. Several catalysts were selected for butane ATR. Thermodynamic reactor conditions (temperature, $O_2$/C, S/C) are varied and reforming characteristics of 2 catalysts (Pt and Rh on ceramic supports) and 1 commercial catalyst (FCR-HC35) have been examined. To understand reaction behaviors in an ATR reactor comprehensively, temperature profiles of reactor were observed. By mass transfer limitation, fuel conversion decreases when GHSV increases. Significant temperature variation along the reactor was observed and it was mainly due reaction kinetics difference between exothermic oxidation and endothermic reforming reaction.

견관절의 유착성 관절낭염 환자에 대한 자가신장운동의 효과 (The Effect of Self Stretching Exercise in Patients with Shoulder Adhesive Capsulitis)

  • 서병도;신형수
    • The Journal of Korean Physical Therapy
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    • 제22권1호
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    • pp.19-26
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    • 2010
  • Purpose: The purpose of this study was to compare the effectiveness of (a) a self stretching exercise (SSE) maintained below the level of pain with (b) physical therapy (PT) performed without pain limitation in patients with adhesive capsulitis. Methods: Forty-three subjects with frozen shoulder were recruited. Subjects were randomly assigned to one of two groups - an experimental group (SSE group, $n_1=18$) and a control group (PT group, $n_2=25$). The duration of each intervention was five weeks. We assessed night pains, range of motion (ROM), and shoulder function. Results: Overall, subjects in both groups improved over five weeks (p<0.05). The change in the PT group was greater (p<0.05) Conclusion: SSE carried out under the pain threshold may be used to treat patients with adhesive capsulitis SSE can be prescribed with PT as part of a home program or of group management.

SCF 시스템의 AAF와 SMF 집적화 설계 (The Design for AAF and SMF Integrated Circuits of SCF System)

  • 조성익;신홍규;김동용
    • 한국통신학회논문지
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    • 제19권5호
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    • pp.781-786
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    • 1994
  • 본 논문에서는 SCF의 입력신호를 제한하여 혼성왜곡을 방지하고, 출력 신호파형을 평활처리 할 수 있도록 연속시간 능동 RC 필터로 구성된 AAF와 SMF의 설계방법을 제시하였다. 그 후 연속시간 능동 RC 필터로 설계된 AAF 와 SMF를 ORBIT 2 m CMOS n-well 공정으로 집적화하여 실험특성을 SPICE 결과와 비교 검토하였다.

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개선된 동작영역을 갖는 복합 트랜지스터 설계 (Design of Composite Transistors with an Improved Operating Region)

  • 이근호;유영규
    • 한국통신학회논문지
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    • 제28권3A호
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    • pp.185-191
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    • 2003
  • 본 논문에서는 문턱 전압의 감소에 의해 넓은 동작 영역을 갖는 새로운 구조의 트랜지스터를 제안하였다. 문턱 전압을 감소시키기 위해 제안된 복합 트랜지스터Ⅰ은 P형 폴디드(P-type folded) 복합 트랜지스터를 이용하였고, 복합 트랜지스터Ⅱ는 제너 다이오드를 이용하였다. 제안된 트랜지스터가 전류원에 의해 동작 영역이 제한되는 현상을 고찰하여 검증하였으며, 제안된 회로들은 0.25㎛ CMOS n-well 공정 파라미터를 이용하여 2.5V 공급 전압하에서 Hspice 시뮬레이션을 통해 그 특성을 검증하였다.

위암 표준진료권고안 (Clinical Practice Guideline of Gastric Cancer in Korea)

  • 김재규
    • Journal of Digestive Cancer Research
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    • 제4권1호
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    • pp.10-16
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    • 2016
  • There were no Korean evidence-based multidisciplinary guidelines for gastric cancer. Experts from related societies developed guidelines de novo to meet Korean circumstances and requirements, including 23 recommendation statements for diagnosis (n=9) and treatment (n=14) based on relevant key questions. The quality of the evidence was rated according to the GRADE evidence evaluation framework and the recommendation grades were classified as either strong or weak. The topics of the guidelines cover diagnostic modalities (endoscopy, endoscopic ultrasound, and radiologic diagnosis), treatment modalities (surgery, therapeutic endoscopy, chemotherapy, and radiotherapy), and pathologic evaluation. Major limitation of the present guideline is that there is no enough evidences in Korea. Therefore, clinical studies about gastric cancer for evidence generation should be conducted.

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