• Korean Journal of Microbiology
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• v.44 no.4
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• pp.282-288
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• 2008

Tissue ischemia resulting from the constriction or obstruction of blood vessels leads to an illness that may affect many organs including the heart, brain, and legs. In recent years, considerable progress has been made in the field of therapeutic angiogenesis and the new approaches are expected to cure those "no-option patients" who are unsuited to conventional therapies. Although single angiogenic growth factor may be successful in inducing angiogenesis, combination of multiple growth factors is increasingly sought these days to augment the therapeutic responses. This trend is proper in light of the fact that blood vessel formation is a complex and multi-step process that requires the actions of many different factors. To meet the growing need for functionally significant blood flow recovery in the ischemic tissues, a novel strategy that can provide concerted actions of multiple factors is required. One way to achieve such a goal is to use a transcription factor that can orchestrate the expression of multiple target genes in the ischemic region and thus induce significant level of angiogenesis. Here, a putative transcription factor, cardiac ankyrin repeat protein (CARP), was evaluated in adenoviral vector context for angiogenic activity in human umbilical vein endothelial cells. The results indicated significant increase in proliferation, capillary-like structure formation, and induction of vascular endothelial growth factor, a typical angiogenic gene. Taken together, these results suggest that CARP represents itself as a novel target for therapeutic angiogenesis and warrants further investigation.

• The KIPS Transactions:PartD
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• v.16D no.4
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• pp.487-496
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• 2009

This paper addresses an indexing scheme capable of efficiently processing range queries in a large-scale trajectory database. After discussing the drawbacks of previous indexing schemes, we propose a new scheme that divides the temporal dimension into multiple time intervals and then, by this interval, builds an index for the line segments. Additionally, a supplementary index is built for the line segments within each time interval. This scheme can make a dramatic improvement in the performance of insert and search operations using a main memory index, particularly for the time interval consisting of the segments taken by those objects which are currently moving or have just completed their movements, as contrast to the previous schemes that store the index totally on the disk. Each time interval index is built as follows: First, the extent of the spatial dimension is divided onto multiple spatial cells to which the line segments are assigned evenly. We use a 2D-tree to maintain information on those cells. Then, for each cell, an additional 3D $R^*$-tree is created on the spatio-temporal space (x, y, t). Such a multi-level indexing strategy can cure the shortcomings of the legacy schemes. Performance results obtained from intensive experiments show that our scheme enhances the performance of retrieve operations by 3$\sim$10 times, with much less storage space.

• Korean Journal of Social Welfare Studies
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• v.49 no.1
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• pp.51-83
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• 2018

This study examines whether the widening gap between income groups is worsening in the distribution of time use, similar to the worsening of income distribution after the IMF. To do this, we conducted multilevel analysis (HLM) on six countries including France, the Netherlands, Spain, the United Kingdom, the United States and Korea. The results of the analysis are as follows. First, in all countries, low income groups have a longer paid working time and shorter leisure time. Second, the low income groups in Korea have the longest paid work time and the shortest leisure time, the lowest level of work-leisure balance, and this aspect has not recovered since the IMF. Third, as the result of multilevel analysis, the lower the household income, the more time paid labor increased and the work-leisure balance decreased. Fourth, while average annual working hours increase paid working time, the expansion of family policy expenditure, redistribution policy and income maintenance policy has reduced it. Fifth, the annual average working hours decreased the work-leisure balance, but the family policy expenditure, the redistribution policy and the income guarantee policy increased the work-leisure balance. The significance of this study is that after the IMF, not only the income distribution but also the inequality among the income class in time use has deepened. Based on the results of the research this study suggests the reinforcement of labor time regulation, the activation of parental leave system, the realization of the income replacement rate, the expansion of the policy related to income redistribution, and the complementary development of the income guarantee and the time guarantee policy as the policy intervention strategy that restructures time.

• 한국노년학
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• v.40 no.1
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• pp.179-196
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• 2020

The purpose of this study was to identify the factors impacting fear of dementia, targeting the aged in the community. The study targeted 258 seniors aged 65 or older attending the senior college or using the senior citizen community center in areas of Jeollannam-do. Data were analyzed using descriptive statistics, t-test, ANOVA, Pearson correlation coefficient and a stepwise multiple linear regression. Fear of dementia of the aged showed significant positive correlations with dementia anxiety, and aged anxiety. dementia anxiety, aged anxiety, dementia experience, use of a hearing aid, religion, level of dementia interest were significant predictors influencing fear of dementia of aged in the community, and these variables accounted for 37.2% of the variance. Therefore, this study suggests that in order to p revent fear of dementia of aged people in the primary health care setting, it is necessary to have a nurse's assessment on the factors affecting dementia as well as a multi-faceted education strategy for proper recognition of dementia.

• Journal of Marine Life Science
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• v.8 no.1
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• pp.87-92
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• 2023

Microplastic particles are ubiquitous in the environment and not standardized particles of size, shape, or type. Therefore, it is very limited to establish a risk assessment framework that accurately evaluated and manage the multi-dimension of marine environment including seawater and sediment based on toxic data. In the study, we review the characteristics and effects of marine environmental microplastic and suggest risk assessment framework (draft) based on the distribution and impact of marine environmental microplastics. Although, the characteristics of environmental microplastic are very widely but the most abundant toxic data are concentrated on unique shape and type, and there are also large gaps of test organism between laboratory-exposed organisms and resident species. Great limitations with respect to toxicity data quality also exist for traditional effect assessment methods, which in reliability of the resulting risk characterizations. However, considering the fact that the international community's movement on microplastics management is gradually strengthening and the pollution level of microplastics in marine environment is increasing, further research on environmental relevant risk assessment technique should be proposed based on the characteristics of microplastics in the marine environment.

• Journal of Korea Entertainment Industry Association
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• v.13 no.5
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• pp.145-153
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• 2019

The present study is a discussion in which the flow of 'social and cultural values' inherent in the creative advertising story is considered against Bart's symbolism and the creative symbol system, and attempted to reproduce the work through the cognitive thinking of the inmates. The interaction of correct social and cultural communication is not just a strategy for persuasion and effectiveness. Starting with these issues, I thought that experiencing the 'symbolic production' and 'cognition interpretation' of the most creative, aesthetic and implicit advertising stories was the realization of concrete cultural values. The reason why I pay attention to advertising as a target tool of the original school is that it gives anyone access to the social and cultural values based on the productivity of meaning, the sharing of meaning and social small-call work by paying attention to the most implicit symbols in a short period of time. I also think that with the trend of the times, it is well worth it as a tool of positive communication for social and cultural member harmony and solving future problems. The reality of social and cultural advertising stories conducted in conjunction with the analysis of meaning at the cognitive thought level is very appropriate to apply in creative classes for college students. The Dong-A Ilbo is a discussion that suggested that the work of realizing the cognitive meaning of advertising stories, a "symbol complex" based on creativity in a complex, multi-media era, will become an age-old communication tool to join university students' strategies for solving future problems

• Korean Journal of Remote Sensing
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• v.39 no.6_3
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• pp.1679-1692
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• 2023

South Korea is a country that emits a large amount of pollutants as a result of population growth and industrial development and is also severely affected by transboundary air pollution due to its geographical location. As pollutants from both domestic and foreign sources contribute to air pollution in Korea, the location of air pollutant emission sources is crucial for understanding the movement and distribution of pollutants in the atmosphere and establishing national-level air pollution management and response strategies. Based on this background, this study aims to effectively acquire spatial information on domestic and international air pollutant emission sources, which is essential for analyzing air pollution status, by utilizing high-resolution optical satellite images and deep learning-based image segmentation models. In particular, industrial parks and quarries, which have been evaluated as contributing significantly to transboundary air pollution, were selected as the main research subjects, and images of these areas from multi-purpose satellites 3 and 3A were collected, preprocessed, and converted into input and label data for model training. As a result of training the U-Net model using this data, the overall accuracy of 0.8484 and mean Intersection over Union (mIoU) of 0.6490 were achieved, and the predicted maps showed significant results in extracting object boundaries more accurately than the label data created by course annotations.

• The Journal of the Convergence on Culture Technology
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• v.10 no.2
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• pp.167-172
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• 2024

In major wars of the 21st century, drones are expanding beyond surveillance and reconnaissance to include land and air as well as sea and underwater for purposes such as precision strikes, suicide attacks, and cognitive warfare. These drones will perform multi-domain operations, and to this end, they will continue to develop by improving the level of autonomy and strengthening scalability based on the High-Low Mix concept. Recently, drones have been used as a major means in major wars around the world, and there seems to be a good chance that they will evolve into game changers in the future. North Korea has also been making significant efforts to operate reconnaissance and attack drones for a long time. North Korea has recently continued to engage in provocations using drones, and its capabilities are gradually becoming more sophisticated. In addition, with the recent emergence of new strategic Drones, wartime and peacetime threats such as North Korea's use of these to secure surveillance, reconnaissance and early warning capabilities against South Korea and new types of provocations are expected to be strengthened. Through this study, we hope to provide implications by analyzing the capabilities of North Korea's strategic Drones, predicting their operation patterns, and conducting active follow-up research on the establishment of a comprehensive strategy, such as our military's drone deployment and counter-drone system solutions.

• Journal of Nutrition and Health
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• v.50 no.6
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• pp.664-678
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• 2017

Purpose: To identify the effectiveness of policy evaluation, consistent monitoring is necessary. This study aimed to carry out mid-term evaluation of objectives and programs related to comprehensive plans for sodium intake reduction by 2020 for Seoul city and then reestablish the objectives of the sodium intake reduction plans. Methods: Literature reviews, data analysis, and reviews of expert focus-groups were performed to evaluate objectives, to develop a new goal, and to identify the priority subjects of the sodium intake reduction programs. In order to examine target populations for the programs, awareness and behaviors related to sodium intakes among Seoul citizens were examined by sex, age, and income level using the 2008~2013 Korea National Health and Nutrition Examination Survey data. Results: Current objectives of the sodium intake reduction plan by 2020 for Seoul city were not appropriate, so objectives were reset to 3,600 mg of sodium intake by 2020 among Seoul citizens with 2% reduction per year. Although sodium intake showed a decreasing trend by year, it was still high, especially in men. The sodium intake reduction programs currently in progress have not been assessed at multiple levels across multiple sectors and have only been assessed fragmentarily. For dietary behavior related to sodium intakes by sex, age, and income level, sodium intake was higher in the group with less than 100 g of fruit intake compared to the group with 100 g or more. Subjects aged 30~59 years and the low household income group showed relatively higher sodium intakes. Based on the data analysis and the expert review, the priority subject of the sodium intake reduction programs was determined to be adult men. In terms of a program strategy for sodium intake reduction, multi-level and setting approaches, including work sites, home, and restaurants, were suggested to reduce sodium intakes of the target subject. Conclusion: The suggested objectives should be consistently monitored by data analysis, and the determined programs need to be phased in over 5 years.

• Korean Business Review
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• v.19 no.1
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• pp.53-80
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• 2006

This research has been accomplished to build up the growth strategies of Kangwon district's small & medium-sized construction firms. For this purpose, we made an investigation of the present situation and status for existing regional small & medium construction firms by analyzing data. Based on the results from this study, the following growth strategies are suggested to gain their competitive advantages. Firstly, most of all, the role of the top manager is the most important factor since most of the top manager for the small & medium-sized construction firms coincide with the owner the firms. Secondly, the specialization strategy is to establish. Above all they concentrate their business capacities on core business. Then, this growth strategy should be based on the selective escalation of functions in order to maintain an appropriate level of construction works. Thirdly, the specialized skills and skilled workers are ensured for competitive advantages. For human resource development, they should train workers to be multi-functioned on the assumption the they could stay at firm until they wish to retire. Finally, the government must also spare no effort to encourage the small & medium-sized construction firms to build up it's competitive power and cultivate it's spontaneous generation power though the reformation of system related whit the small and medium construction industry.