• Title/Summary/Keyword: Mortalities

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The Prognostic Factors of Traumatic Diaphragmatic Rupture (외상성 횡격막 파열에서 예후에 영향을 미치는 인자)

  • Cho, Sukki;Lee, Eung-Bae;Seok, Yang-Ki
    • Journal of Chest Surgery
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    • v.43 no.1
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    • pp.47-52
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    • 2010
  • Background: Traumatic diaphragmatic rupture is not common, but it requires swiftly performing an emergency operation. This study was conducted to evaluate the prognostic factors for mortality after surgically treating traumatic diaphragmatic rupture. Material and Method: From Jan 2001 to Dec. 2008, we experienced 37 cases of multiple traumas with diaphragmatic injuries that were confirmed by surgical procedures. We evaluated various factors, including the type of injury, the associated injuries, the preoperative vital signs, the ISS, the time until surgery and the rupture size. Result: There were 30 patients with blunt trauma and 7 patients with penetrating trauma. Thirty-four patients had associated injuries and the mean ISS was 20.8. Postoperative complications occurred in 11 patients and hospital mortalities occurred in 6 patients. The prognostic factors that had an influence on the postoperative mortalities were the preoperative intubation state, the patient who exhibited hypotension and a high ISS. Conclusion: Traumatic diaphragmatic rupture is just one part of multiple traumas. The postoperative mortalities might depend on not only on the diaphragmatic rupture itself, but also on the severity of the associated injuries.

Biological Control of Onion Maggot and Tobacco Cutworm with Insect-parasitic Nematodes, Steinernema feltiae and Heterorhabditis heliothidis (곤충기생성 성충, Steinernema feltiae와 Heterorhabditis heliothidis를 이용한 고자리파리 및 담배거세미나방의 생물적 방제)

  • ;Harry K.Kaya;David K. Red
    • Korean journal of applied entomology
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    • v.27 no.4
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    • pp.185-189
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    • 1988
  • Laboratory trials were conducted for control of onion maggot and tobacco cutworm with ento¬mogenous nematodes. The onion maggot, Delia antiqua, was exposed to Steinernema feltiae at concentration of 0,30,60, 120 or 240 nematodes per larva, and to Heterorhabditis heliot-hidis at concentration of 0, 10, 20, 40 or 80 nematodes per larva. Mortalities of the maggot ranged from 80 to 100% in S. feltiae and from 63.3 to 100% in H. heliothidis. The tobacco cutworm, SpodoPtera litura was exposed to S. feltiae at concentration of 0,50,100,200 or 400 nematodes per larva and to H. heliothidis at concentration of 0,20,40,80 or 160 nemat¬odes per larva with or without kale in petri dish. The 3rd instar larvae of the tobacco cutworm was more susceptible to both nematode species than the 4th or 5th instar at low concentration. Mortalities of the 3rd instar were 100% in S. feltiae and 67.7-100% in H. heliothidis while those of 4th and 5th instar ranged 76.7-100% and 43.3-100% in S. feltiae, and 36.7-90% and 3.3-90% in H. heliothidis, respectively. Mortalities of the tobacco cutworm larvae decreased when the nematodes were sprayed on the kale leaves in petri dish except 3rd instar.

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Laboratory Evaluation of Entomopathogenic Nematodes, Steinernema carpocapsae and Heterorhabditis bacteriophora against Some Forest Insect Pests (곤충 병원성 선충 Steinernema carpocapsae와 Heterorhabditis bacteriophora를 이용한 삼립해충의 방제)

  • ;Harry K. Kaya
    • Korean journal of applied entomology
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    • v.30 no.4
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    • pp.227-232
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    • 1991
  • The pathogenicity of entomopathogenic nematodes Sfeinernema earpocapsae and Heferorhabditis baeferiophora was evaluated against forest insect pests, alder leaf beetle Agelastiea eoerulea, pellucid zygaenid Pryeria siniea, and box-tree pyralid Glyphodes perspeetalis. Alder leaf beetle larvae were exposed to S. earpocapsae at concentration of 0, 25, 50, and 100 nematodes and to H. baeferiophora at concentration of 0, 10, 20, and 40 nematodes per larva on alder leaves. Mortalities of 1st instar lavae were 85.4 $\pm$ 4.1-100%, 2nd instar larvae 80.0 $\pm$ 5.8-100%, and 3rd instar larvae 65.0 $\pm$ 10.8-100% in S. earpocapsae and those of 1st instar larvae were 82.5 $\pm$ 6.9-100%, 2nd instar larvae 77.5 $\pm$ 4.7-100%, and 3rd instar larvae 55.0 $\pm$ 13.5-100% in H. baeferiophora treatment. When pellucid zygaenid larvae were exposed to S. earpocapsae at concentration of 0, 5, 10, 20, 40, and 80 nematodes and to H. baeteriophora at concentration of 0, 2, 5, 10,20, and 40 nematodes per larva, mortalities were 98.9 $\pm$ 1.1-100% in S. earpocapsae and 26.7 $\pm$ 5.1-74.5 $\pm$ 6.2% in H. baeferiophora. The mortalities of box-tree pyralid larvae were 97.8 $\pm$ 1.5-100% in S. earpocapsae treated with concentration of 0,20,40, and 80 nematodes per larva and those were 92.0 $\pm$ 6.2-98.9 $\pm$ 1.1 % in H. baeferiophora treated with con'||'&'||'not;centration of 0, 10, 20, and 40 nematodes per larva.

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Studies on the Natural Mortality of the Young Short Necked Clam, Tapes Japonica-II . Resistance to Temperature , Salinity and Exposure for the Young Short Necked Clam (바지락치패의 폐사에 관한 연구-II 바지락 치패의 온도, 염분, 노출에 대한 저항성)

  • CHOE, Sang
    • The Korean Journal of Zoology
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    • v.9 no.1
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    • pp.7-15
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    • 1966
  • In a previous paper, the dirunal and monthly changes of the tidal flat temperature and chlorinity were observed. In this paper the resistance of the young short necked clam in various growth stages to the temperature, to the chlorinity and to the exposure were studies. The young clam used were in early (E), medium (M) and late (L) young stages whose shell lengths were 2.0-3.5mm, 9.0-11.0mm. and 14.0-16.0mm., respectively. The results were : 1. At various sea water temperatures , the chlorinity resistance of the young clam was directly proportional to the shell length. 2. When both inadequate sea water temperature and abnormal chlorinity are simultaneously applied, the resistance of these young clams was more markedly reduced than the case of applying either one of these conditions. 3. In clams of M and L, no lethal effect were observed when daily immersion of four to eight hours for a week into the sea water of any concentration of chloriity at 26-34$^{\circ}C$, whereas in E, 37-90% of mortalities were obtained by immersion of eight hours daily into both the fresh water and the sea water of higher chloriniites (more than 23.5$\textperthousand$ Cl) at the same temperature above. 4. The lower critical thermal maximum for lethal to the young clam was 38$^{\circ}C$. With four hours immersion daily at the water temperature of 38$^{\circ}C$, the mortalities of E, M and L to the lower chlorinities (less than 6.7$\textperthousand$Cl) were 100, 70-100 and 27-37% respectively ; to the higher chlorinities (more than 23.5$\textperthousand$Cl) 10-70, 10-37 and 3 % respectively ; to the normal range of chlorinities (13.4-16.8$\textperthousand$Cl) 0-13, 3 and 0 % respectively. 5. No lethal effects were observed in E and M clams immersed continuously for seven days in sea water with chlornities of 7.2 -21.7$\textperthousand$Cl at 18-24$^{\circ}C$, while notable mortalities were observed in E which had been kept at lower (less than 4.8$\textperthousand$ Cl) and higher (more than 24.1$\textperthousand$ Cl) chlorinites. 6. Although the resistance of the young clam to the chlorinity may have to be related closely to the life history of the clam prior subject to the experiment, the adapted chlorinity range was 7.2-19.3$\textperthousand$ Cl and the optimum range was 13.4-16.8$\textperthousand$Cl. 7. Remarkable lethal effects were observed for the E and M clams to the exposure temperature of 38$^{\circ}C$ whereas the L and had no such fatal results.

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Mouse Single Oral Dose Toxicity Test of Lactobacillus-fermented Araliae Continentalis Radix Aqueous Extracts (fACR) (독활의 복합 유산균 발효 추출액의 마우스에 대한 단회경구투여 독성시험)

  • Jung, Young-Mi;Ku, Sae-Kwang;Lee, Dong Sub;Kwon, Kisang
    • Journal of Life Science
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    • v.26 no.2
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    • pp.204-211
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    • 2016
  • The objective of this study was to obtain acute (single) oral dose toxicity information on Lactobacillus-fermented Araliae Continentalis Radix aqueous extracts (fACR) in female and male ICR mice, as compared with Araliae Continentalis Radix aqueous extracts (ACR). After administering a single oral dose of fACR, no treatment-related mortalities were observed within 14 days after the end of treatment up to 2,000 mg/kg, the maximum dosage for rodents of both sexes; moreover, no fACR treatment-related changes in the body and organ weights, clinical signs, necropsy, and histopathological findings were detected in this experiment. In addition, no ACR 2,000 mg/kg treatment-related mortalities, clinical signs, body and organ weights, or gross and histopathological findings were observed, as compared with equal genders of vehicle control. The results obtained in this study suggest that fACR is non-toxic in mice and is, therefore, likely to be safe for clinical use. The LD50 and approximate LD in female mice and male mice, respectively, were considered after a single oral dose of fACR over 2,000 mg/kg, the maximum dosage for rodents. In addition, no specific targets or clinical signs were detected in the present study. ACR 2,000 mg/kg-treated mice also did not show any treatment-related mortalities, clinical signs, changes to body and organ weights, or gross and histopathological findings, as compared with equal genders of vehicle control.

Lack of Health Insurance Increases All Cause and All Cancer Mortality in Adults: An Analysis of National Health and Nutrition Examination Survey (NHANES III) Data

  • Cheung, Min Rex
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.4
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    • pp.2259-2263
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    • 2013
  • Background: Public use National Health and Nutrition Examination Survey (NHANES III) and NHANES III linked mortality data were here applied to investigate the association between health insurance coverage and all cause and all cancer mortality in adults. Patients and Methods: NHANES III household adult, laboratory and mortality data were merged. Only patients examined in the mobile examination center (MEC) were included in this study. The sampling weight employed was WTPFEX6, SDPPSU6 being used for the probability sampling unit and SDPSTRA6 to designate the strata for the survey analysis. All cause and all cancer mortalities were used as binary outcomes. The effect of health insurance coverage status on all cause and all cancer mortalities were analyzed with potential socioeconomic, behavioral and health status confounders. Results: There were 2398 sample persons included in this study. The mean age was 40 years and the mean (S.E.) follow up was 171.85 (3.12) person months from the MEC examination. For all cause mortality, the odds ratios (significant p-values) of the covariates were: age, 1.0095 (0.000); no health insurance coverage (using subjects with health insurance), 1.71 (0.092); black race (using non-Hispanic white subjects as the reference group) 1.43, (0.083); Mexican-Americans, 0.60 (0.089); DMPPIR, 0.82, (0.000); and drinking hard liquor, 1.014 (0.007). For all cancer mortality, the odds ratio (significant p-values) of the covariates were: age, 1.0072 (0.00); no health insurance coverage, using with health coverage as the reference group, 2.91 (0.002); black race, using non-Hispanic whites as the reference group, 1.64 (0.047); Mexican Americans, 0.33 (0.008) and smoking, 1.017 (0.118). Conclusion: There was a 70% increase in risk of all cause death and almost 300% of all cancer death for people without any health insurance coverage.

The Relationship between GDI(Gender Related Development Index) and the maternal and Child Mortality (여성관련개발지수와 모성 및 영아 사망률과의 관계)

  • 신미경;김한중;김모임;박은철;박종연
    • Health Policy and Management
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    • v.10 no.2
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    • pp.120-130
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    • 2000
  • Studies on the relation between socio-economic factors and metermal and child health have found that poverty, lack of edcation, inappropriate health serives are affecting to maternal and child health. The Gender Related Development Index (GDI) focuses on equality between men and women as well as on the average achiement of all people taken together, using same cariables as the Human Development Index (HDI) which are life expectancy, literacy rate, and per capita GDP. This research is to inverstigate whether HDI and GDI are useful determinants for maternal infant mortality. Using 146 UN member countries date, we condented multiple regression analysis for maternal and infant mortality with three models which are Model(individual variables-literacy rate, per capita GDP), Model(HDI) and Model(GDI). The results showed that HDI and GDI are powerful determinants of both maternal and infant mortality, respectively HDI($\beta$=-1.18, t=3.3; $\beta$=1.04, t=5.1) GDI($\beta$=-1.44, t=3.9; $\beta$=1.28, t=6.5) The higher power in model with GDI for both maternal and infant mortalities represented that GDI was more powerful determinant of maternal and infant mortality, than HDI respectively HDI($R^2$=0.824, $R^2$=0.842), GDI($R^2$=0.834, $R^2$=0.865). In conclusion, the maternal and infant mortalities are explained by GDI than HDI and may be lower in the societies where there are less discimination between men and women.

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Studies on the Safety of Artemisiae Capillaris Herba - With the Perinatal and Lactational Reproductive Toxicity - (인진의 안정성에 대한 연구 - 주산$\cdot$수유기 생식 독성을 중심으로 -)

  • Wang Wu-Hao;Park Jae-Hyun
    • The Journal of Korean Medicine
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    • v.26 no.2 s.62
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    • pp.32-51
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    • 2005
  • Objectives: To study the effect of Artemisiae Capillaris Herba extracts, that have been used as oriental medicine to treat liver disease, on the perinatal and lactational n;)productive toxicity of SD rats when administered by oral lavage. Methods: Female SD rats were dosed from 6 days of gestation to 3 weeks postpartum. This was conducted in accordance with the recommendations of the KFDA Guidelines for Detection of Toxicity to Reproduction for Medicinal Products. Results: No Artemisiae Capillaris Herba extracts treatment-related changes in clinical signs, mortalities, implantation number, dead fetus number, loss rate of fetus, number of live young, survival rate of fetus, sex ratio of live young, external anomalies, pregnancy periods, viability index, lactational index, survival rate of litters at 4 days after birth or delivery index were demonstrated in any dosed levels in this study. However, the body weight and gains, food consumption and absolute organ weights of brain, adrenal glands, liver, spleen, kidney, ovaries and heart were significantly increased in 2000 or 1000mg/kg-dosing groups and the relative organ Weights of adrenal glands were significantly increased in 2,000mg/kg-dosing groups. Therefore, it was concluded that this increase was natural according to growth. Also, no changes of gross findings, clinical signs, mortalities, body weight and gains, physical development results, necropsy findings, organ weight, faculty test, open filed test and water-filled simple T-maze test, copulation, fertility, pregnancy indices, body weight and gains during gestation periods, necropsy findings, corpora lutea number, implantation number, implantation rate, dead fetus number, post-implantation loss rate, live young, post-implantation survival rate, sex ratio of live young, external anomalies and individual body weights of live young were demonstrated in any dosed levels in this study. Conclusions: It is considered that the NOAEL (No-Observed-Adverse-Effect Level) for perinatal and lactational reproductive toxicity of Artemisiae Capillaris Herba extracts was up to 2000mg/kg/day because no changes of other perinatal and lactational reproductive indices were demonstrated.

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Investigation of interference current distribution in a long line scallop cage aquaculture (수하식 큰가리비 양식의 채롱간 조류의 흐름 간섭현상 규명)

  • Kim, Hyun-Young;OH, Bong-Se;Cha, Bong-Jin;Park, Mi-Seon
    • The Korean Journal of Malacology
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    • v.30 no.3
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    • pp.273-279
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    • 2014
  • The mass mortalities have been occurring of Korean scallop Patinopecten yessoensis from 1997's to now in Korea east sea. Cages behavior and interference effect (common name; curtain effect) between scallop cages were investigated in culture grounds on the eastern coastal waters of Korea for understand to mechanism of rising about mass mortalities of Korean scallop quickly. The first experiment was carried out in circulating water channel to assess inclination angel from relationship between velocity and cages interval, velocity with culture cages position. An angle of inclination of scallop culture cages were 94.6 to 92.3 degree under a several velocity which were from 0.1 m/s and 131.9 to 118.1 degree under 0.5 m/s with cages interval were 1 m, 94.3 to 91.0 degree under velocity is 0.1 m/s and 133.2 to 122.4 degree under 0.5 m/s with cages interval were 1.5 m and 94.6 to 96.4 degree under velocity is 0.1 m/s and 131.7 to 131.8 under 0.5 m/s with cages interval were 2 m. The second experiment was designed to prove the tank test. Velocities were measured inside and outside of the scallop culture ground at eastern sea of Korea. The velocity of inside of the culture was the slowest as 0.1m/s. In this result, interference between former cage and after cage was occurred.

Effects of Dietary Supplementation of a Citrus By-product on Growth Performance, Innate Immunity and Tolerance of Low Water Temperature in Red Seabream Pagrus major (사료 내 감귤착즙박 첨가가 저수온에서 사육된 참돔(Pagrus major)의 성장, 비특이적 면역반응 및 수온자극 스트레스에 미치는 영향)

  • Song, Jin-Woo;Park, Sang-Hyeon;Lee, Cho-Rong;Lee, Kyeong-Jun
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.46 no.4
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    • pp.399-406
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    • 2013
  • Our aim was to determine the effects of a citrus by-product (CBP) and CBP fermented by Lactobacillus plantarum (LP-CBP), provided as dietary supplements, on the growth performance, feed utilization, innate immunity and temperature tolerance of red seabream. A diet without inclusion of CBP or LP-CBP was used as a control and four other experimental diets were formulated to replace wheat flour by 4% and 8% of either CBP or LP-CBP (designated as Con, LP-CBP4%, LP-CBP8%, CBP4% and CBP8%, respectively). Experimental diets were fed to triplicate groups of 25 fish (initial body weight, 55.0 g) for 9 weeks. Growth performance and feed utilization were not significantly different among all the groups. Bone collagen content was significantly increased by supplementation with CBP and LP-CBP. Vitamin C concentration tended to be higher in livers of fish fed the supplements than in the control group. Myeloperoxidase, lysozyme and superoxide dismutase activities were higher in fish fed CBP or LP-CBP than in fish fed the control diet. When fish were exposed to low water temperature, cumulative mortalities of those fed CBP or LP-CBP supplemented diets were lower (29%, 33%, 34% and 33% mortalities for LP-CBP4%, LP-CBP8%, CBP4% and CBP8%, respectively) than in the control group (58%). Therefore, inclusion of either CBP or LP-CBP at up to 8% in red seabream diet brings benefits through enhanced innate immunity and better tolerance of low water temperature.