• Bulletin of the Korean Chemical Society
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• 제27권1호
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• pp.71-76
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• 2006

Porous polymer monolithic columns were prepared by the direct free radical copolymerization of methacrylic acid and ethylene glycol dimethacrylate within the confines of a chromatographic column in the presence of toluene-dodecanol as a porogenic solvent. The separation characteristics of the monolithic columns were tested by a homologous series of xanthine derivatives, theophylline and caffeine. The effects of the polymerization mixture composition and polymerization condition, mobile phase composition, flow rate and temperature on the retention times and separation efficiencies were investigated. The results showed that the selection of correct porogenic solvents and appropriate polymerization conditions are crucial for the preparation of the monolithic stationary phases. The separation efficiency was only extremely weakly dependent on flow rate and temperatures. Hydrogen-bonding interaction played an important role in the retention and separation. Compared with conventional particle columns, the monolithic column exhibited good stability, ease of regeneration, high separation efficiency and fast analysis.

• Structural Engineering and Mechanics
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• 제23권1호
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• pp.43-61
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• 2006

An investigation of the effectiveness of the interface treatment when column concrete jacketing is performed is presented. Alternative methods of interface connection were used in order to investigate the performance of strengthened concrete columns. These connecting techniques involved roughening the surface of the original column, embedding steel dowels into the original column and a combination of these two techniques. The experimental program included three strengthened specimens, one original specimen (unstrengthened) and one as-built specimen (monolithic). The specimens represented half height full-scale old Greek Code (1950's) designed ground floor columns of a typical concrete frame building. The jackets of the strengthened specimens were constructed with shotcrete. All specimens were subjected to displacement controlled earthquake simulation loading. The seismic performance of the strengthened specimens is compared to both the original and the monolithic specimens. The comparison was performed in terms of strength, stiffness and hysteretic response. The results demonstrate the effectiveness of the strengthening methods and indicate that the proper construction of a jacket can improve the behaviour of the specimens up to a level comparable to monolithic behaviour. It was found that different methods of interface treatment could influence the failure mechanism and the crack patterns of the specimens. It was also found that the specimen that combined roughening with dowel placement performed the best and all strengthened columns were better at dissipating energy than the monolithic specimen.

• Korean Chemical Engineering Research
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• 제43권5호
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• pp.603-608
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• 2005

주조된 매크로 다공성 poly(glycidyl methacrylate-co-ethylene glycol dimethacrylate) 막대를 간단한 주형 과정을 거쳐서 실험실 내 튜브모양의 주형인 크로마토그래피 칼럼($4.6{\times}100mm$)을 사용하여 자유 라디칼 중합에 의해 만들었다. 이는 에폭시 그룹이 유도된 일체형 칼럼과 황산을 이용한 에폭시드 그룹의 화학적인 변형과정을 이용하였다. 단량체 및 포로겐(세공을 생성하는 물질)의 비율, 온도 등 중합반응의 조건을 변화시켜서 세공크기를 조절하여 물질의 체류시간에 영향을 미쳤다. 본 연구에서는 주조된 일체형 칼럼을 이용하여 카페인과 트립토판을 분리하였으며, 중합원료조성이 일체형 칼럼의 효율과 선택도 그리고 분리도에 미치는 영향을 고찰하였다.

• Bulletin of the Korean Chemical Society
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• 제33권11호
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• pp.3727-3734
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• 2012

An analytical method has been developed for the rapid determination of perfluorinated compounds (PFCs) in human serum samples. The extraction and purification of PFCs from human serum were performed by the modified method of previous report. Ten PFCs were rapidly separated within 3.3 min by C18-monolithic column liquid chromatography (LC) and detected by electrospray ionization (ESI) tandem mass spectrometry (MS/MS) in negative ion mode. The runtime of PFCs on monolithic column LC was up to 4-fold faster than that on conventional column LC. The effect of triethylamine (TEA) to the mobile phase has investigated on the overall MS detection sensitivity of PFCs in ESI ionization. Quantification was performed by LC-MS/MS in multiple-ion reaction monitoring (MRM) mode, using $^{13}C$-labeled internal standards. Method validation was performed to determine recovery, linearity, precision, and limits of quantification, followed by, the analysis of a standard reference material (SRM 1957 from NIST). The overall recoveries ranged between 81.5 and 106.3% with RSDs of 3.4 to 16.2% for the entire procedure. The calibration range extended from 0.33 to 50 $ng\;mL^{-1}$, with a correlation coefficient ($R^2$) greater than 0.995 and the limits of quantification with 0.08 to 0.46 $ng\;mL^{-1}$. This approach can be used for rapid and sensitive quantitative analysis of 10 PFCs in human serum with high performance and accuracy.

• 한국연초학회지
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• 제32권1호
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• pp.35-40
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• 2010

This study was carried out to enhance the analytical methods of phenolic compounds in mainstream cigarette smoke using high efficiency column and RRLC(Rapid Resolution Liquid Chromatography) system, and to compare these methods. RRLC system offers significantly faster results with higher data quality of phenolic compounds than conventional HPLC, but it is disadvantage that it is expensive. On the other hand, the method using monolithic column offers faster results by the use of conventional HPLC system without new equipment introduction. In this study, we used the linear type smoking machine and Health Canada method for pre-treatment process of phenolic compounds. The analysis time of phenolic compounds using RRLC and monolithic column was individually 8 and 15 minutes, whereas in the conventional HPLC it was 45 minutes. These new methods were accompanied with the minimal solvent consumption and had lower analysis costs. Also, we proved that there were no difference between new methods and conventional method in accuracy by statistic.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2004년도 추계 학술발표회 제16권2호
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• pp.619-622
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• 2004

In this study, a moment resisting precast concrete beam-column connection is proposed. An experimental study was carried out to investigate the connection behavior subjected to cyclic loading. Three precast beam-column interior connections and one monolithic connection were tested. Variable included the detailing used at the joint to achieve structural constructability and the location of mild steel reinforcement and high strength bar. During specimen fabrication, the joint details enables ease and speed of construction. Connection performance is evaluated on the basis of ductility, energy dissipation capacity, connection strength, and drift capacity. Based on test results, the precast concrete beam-column connection is capable of matching or exceeding the performance of the monolithic connection.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2004년도 추계 학술발표회 제16권2호
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• pp.85-88
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• 2004

In this study, a simple moment-resisting precast concrete beam-column connection is proposed for highly seismic zone using dywidag ductile rod [DDC]. DDC is superior system for ductility, energy dissipation capacity, connection strength, and drift capacity. A study was carried out to investigate the connection behavior subjected to cyclic inelastic loading. Four Precast beam-column interior connections and one monolithic connection will be tested. The variables will be examined were the strength relationship between joint's ductile rod and beam reinforcement for gain energy dissipation capacity. The specimens will be tested only reverse cyclic loading in accordance with a prescribed displacement history. Connection performance is evaluated on the basis of ductility, energy dissipation capacity, connection strength, and drift capacity. the precast connection using DDC is capable of matching of exceeding the performance of the monolithic connection and thereby provides moment-resisting behavior.

• Bulletin of the Korean Chemical Society
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• 제34권2호
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• pp.447-452
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• 2013

In this study we report a new method for the synthesis of a silica monolithic column bed with bimodal pores (throughpores and mesopores). The template induced synthesis method was used to direct bimodal pores simultaneously instead of the usual post base-treating method. Block polymer Pluronic F127 was chosen as a dual-function template to form hierarchically porous silica monolith with both macropores and mesopores. This is a simplification of the method of monolithic column preparation. Poly(ethylene glycol) was used as a partial substitute for F127 can effectively prevent shrinkage during the monolith aging process without losing much surface area (944 $m^2/g$ to 807 $m^2/g$). More importantly, the resultant material showed a much narrower mesopore size (centered at 6 nm) distribution than that made using only F127 as the template reagent, which helps the mass transfer process. The solvent washing method was used to remove the remaining organic template, and it was proved to be effective enough. The new synthesis method makes the fabrication of the silica monolithic column (especially capillary column) much easier. All the structure parameters indicate that monolith PFA05 prepared by the above method is a good material for separation, with the merits of much higher surface area than usual commercial HPLC silica particles, suitable mesopore volume, narrow mesopore size distribution, low shrinkage and it is easily prepared.

• KSBB Journal
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• 제21권5호
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• pp.401-404
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• 2006

MAA와 EGDMA를 단량체 및 가교제로 한 일체형 컬럼은 친수성의 구조표면을 하고 있어 쉽게 시료와 수소결합 등 강한 상호작용을 할 수 있다. 본 실험에서는 카페인과 트립토판을 분리물질로 선택하였으나 완전한 분리도를 얻을 수가 없었다. 이는 일체형 컬럼의 제조 시 여러 요인에 기인하다. 중합혼합반응물질의 양의 조성과 반응조건이 적절하지 못하는 등 원인으로 생각된다. 따라서 일체형 컬럼의 분리도를 향상시키기 위한 많은 실험이 요구된다.

• 한국세라믹학회지
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• 제49권4호
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• pp.369-374
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• 2012

Based on the structure feature of a tree, a cylindrical $Ti_2AlC$/graphite layered composite has been fabricated through heat treating a graphite column and six close-matched thin wall $Ti_2AlC$ cylinders bonded with the $Ti_2AlC$ powders at $1300^{\circ}C$ and low oxygen partial pressure. SEM examination reveals that the bond interlayers between cylinders or that between cylinder and column are not fully dense without any crack formation. During the compressive test, the strain of the $Ti_2AlC$/graphite layered composite is about twice higher than that of the monolithic $Ti_2AlC$ ceramic, and the compressive strength of the layered composite is 348 MPa. The layered composite show the noncatastrophic fracture behaviors due to the debonding and shelling off of the layers, which are different from the monolithic $Ti_2AlC$ ceramic. The mechanism of the improved deformation capacity and noncatastrophic failure modes are attributed to the presence of the central soft graphite column and cracks deflection by the bond interlayers.