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Sleep Duration and Cancer Risk: a Systematic Review and Meta-analysis of Prospective Studies

  • Zhao, Hao;Yin, Jie-Yun;Yang, Wan-Shui;Qin, Qin;Li, Ting-Ting;Shi, Yun;Deng, Qin;Wei, Sheng;Liu, Li;Wang, Xin;Nie, Shao-Fa
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.12
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    • pp.7509-7515
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    • 2013
  • To assess the risk of cancers associated with sleep duration using meta-analysis of published cohort studies, we performed a comprehensive search using PubMed, Embase and Web of Science through October 2013. We combined hazard ratios (HRs) from individual studies using meta-analysis approaches. A random effect dose-response analysis was used to evaluate the relationship between sleep duration and cancer risk. Subgroup analyses and sensitivity analyses were also performed. Publication bias was evaluated using Funnel plots and Begg's test. A total of 13 cohorts from 12 studies were included in this meta-analysis, which included 723, 337 participants with 15, 156 reported cancer outcomes during a follow-up period ranging from 7.5 to 22 years. The pooled adjusted HRs were 1.06 (95% CI: 0.92, 1.23; P for heterogeneity =0.003) for short sleep duration, 0.91 (95% CI: 0.78, 1.07; P for heterogeneity <0.0001) for long sleep duration. In subgroup analyses stratified by cancer type, long duration of sleep showed an inverse relation with hormone-related cancer (HR=0.79; 95% CI: 0.65, 0.97; P for heterogeneity =0.009) and a greater risk of colorectal cancer (HR=1.29; 95% CI: 1.09, 1.52; P for heterogeneity =0.346). Further meta-analysis on dose-response relationships showed that the relative risks of cancer were 1.00 (95% CI: 0.99, 1.01; P for linear trend=0.9151) for one hour of sleep increment per day, and 1.00 (95% CI: 0.98, 1.01; P for linear trend=0.7749) for one hour of sleep increment per night. No significant dose-response relationship between sleep duration and cancer was found on non-linearity testing (P=0.5053). Our meta-analysis suggests a positive association between long sleep duration and colorectal cancer, and an inverse association with incidence of hormone related cancers like those in the breast. Studies with larger sample size, longer follow-up times, more cancer types and detailed measure of sleep duration are warranted to confirm these results.

Effect of Green Tea and Saw Dust Contents on Dynamic Modulus of Elasticity of Hybrid Composite Boards and Prediction of Static Bending Strength Performances (이종복합보드의 동적탄성률에 미치는 녹차와 톱밥 배합비율의 영향 및 정적 휨 강도성능의 예측)

  • Park, Han-Min;Lee, Soo-Kyeong;Seok, Ji-Hoon;Choi, Nam-Kyeong;Kwon, Chang-Bae;Heo, Hwang-Sun;Byeon, Hee-Seop;Yang, Jae-Kyung;Kim, Jong-Chul
    • Journal of agriculture & life science
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    • v.46 no.2
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    • pp.9-17
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    • 2012
  • In this study, in addition to the green tea - wood fiber hybrid composite boards of previous researches, to make effective use of saw dust of domestic cypress tree with functionalities and application as interior materials, eco-friendly hybrid composite boards were manufactured from wood fiber, green tea and saw dust of cypress tree. We investigated the effect of the component ratio of saw dust and green tea on dynamic MOE (modulus of elasticity). Dynamic MOE was within 1.41~1.65 GPa, and showed the highest value in wood fiber : green tea : saw dust = 50 : 40 : 10 of the component ratio, and had the lowest value in 50 : 30 : 20 of component ratio. These values were 1.4~1.6 times higher than static bending MOE of wood fiber - saw dust - green tea hybrid composite boards, and were 2.0~2.9 times lower than those of green tea - wood fiber hybrid composite boards reported in the previous researches. From the results of correlation regression analyses between dynamic MOE and static strength performances, a very high correlation coefficients were obtained, therefore it was found that static bending strength performances can be estimated with a high reliability from dynamic MOE.

A Study of MOE Establishment for Improving the Credibility of UGV Effectiveness Analysis (무인지상로봇 효과분석의 신뢰성 향상을 위한 효과척도 설정방안 연구)

  • Lee, Jaeyeong;Pyun, Jaijeong;Kim, Chongman
    • Journal of Applied Reliability
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    • v.14 no.3
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    • pp.197-202
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    • 2014
  • In the 21st century, the roles of UGV in the ground battle draw its attention and many research about how to use it is going on globally, but not many study is doing about how to measure its combat effectiveness in the battle. Basically, the effectiveness of UGV is different from its mission profile. Hence, we proposed Measures Of Effectiveness which can measure the UGV effectiveness based on five different missions such as mine detection, nbc detection, reconnaissance, rescue, and fire mission. We expect that these Measures Of Effectiveness proposed are able to contribute to increase the credibility of the study results for UGV effectiveness. We also hope that this paper can stimulate to expand the research scope and related field about UGV effectiveness in the future.

Study on Stress Waves for Development of Glulam from Domestic Small Diameter Log (II) - Static Bending Properties of Glulam Member - (국산 소경재를 이용한 집성재 개발을 위한 응력파 연구(II) - Glulam 부재의 휨강도 특성 -)

  • Cha, Jae-Kyung
    • Journal of the Korean Wood Science and Technology
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    • v.24 no.4
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    • pp.7-14
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    • 1996
  • 두께가 20mm와 30mm이고 폭이 40mm와 60mm 인 길이 600mm의 낙엽송 제재목에 응력파 시험과 휨강도 시험을 실시하였다. 모든 시험편은 생재 상태로 구입 후 함수율 약 13%로 조습 처리하여 응력파 시험과 휨강도 시험을 시행하였다. 휨 영계수와 휨강도는 두께가 큰 것이 작게 나타났다. 최상의 상관관계는 휨 영계수와 양 표면에서 구한 값의 평균값을 사용한 응력파 속도 및 영계수 사이에 나타났다. 휨 영계수와 관계에서 응력파 영계수는 응역파 속도 보다 더 확연한 옹이의 영향을 보였다.

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Shearing characteristics of slip zone soils and strain localization analysis of a landslide

  • Liu, Dong;Chen, Xiaoping
    • Geomechanics and Engineering
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    • v.8 no.1
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    • pp.33-52
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    • 2015
  • Based on the Mohr-Coulomb failure criterion, a gradient-dependent plastic model that considers the strain-softening behavior is presented in this study. Both triaxial shear tests on conventional specimen and precut-specimen, which were obtained from an ancient landslide, are performed to plot the post-peak stress-strain entire-process curves. According to the test results of the soil strength, which reduces from peak to residual strength, the Mohr-Coulomb criterion that considers strain-softening under gradient plastic theory is deduced, where strength reduction depends on the hardening parameter and the Laplacian thereof. The validity of the model is evaluated by the simulation of the results of triaxial shear test, and the computed and measured curves are consistent and independent of the adopted mesh. Finally, a progressive failure of the ancient landslide, which was triggered by slide of the toe, is simulated using this model, and the effects of the strain-softening process on the landslide stability are discussed.

The Effects of Drying Schedules on the Bending Properties of Lodgepole Pine Dimension Lumber Treated with CCA (건조 Schedule이 CCA 처리 Lodgepole Pine 각재의 휨강도 성질에 미치는 영향)

  • Kim, Gyu-Hyeok
    • Journal of the Korean Wood Science and Technology
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    • v.19 no.2
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    • pp.65-71
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    • 1991
  • 본 연구는 CCA 처리재의 재건조(再乾燥)시 적용된 건조 스케쥴 (통상(通常) 열기건조(熱氣乾燥)와 고온건조(高溫乾燥) 스케쥴)이 처리재의 휨강도(强度) 성질에 미치는 영향을 고찰하고자 수행되었다. 탄성계수(彈性係數)(MOE), 그리고 비파괴시험(非破壞試驗)에 의해 얻어진 동적(動的) 탄성계수 (Dynamic MOE) 및 대수감쇠율(對數減衰率)(Logarithmic decrement) 은 처리후 재건조에 의해 큰 영향을 받지 않았다. 반면에 적용된 건조 스케쥴에 관계없이 재건조시 심각한 파괴계수(破壞係數)(MOR)의 감소가 파괴계수 분포의 모든 영역에서 초래되었다. 그러나 통상 열기건조(최대 건구온도=$71^{\circ}C$)와 고온건조(건구온도=$110^{\circ}C$) 서로간에는 감소의 정도에 큰 차이가 없었다. 따라서, 처리재의 재건조사 심각한 파괴계수의 감소가 용인(容認)되지 않는다면 CCA로 처리된 Lodgepole pine 각재의 재건조는 미국 연방 임산물 시험장의 Lodgepole pine의 통상 열기건조 스케쥴 (T9-C3) 보다 온화(溫和)한 조건으로 실시되어야 할 것이다.

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