• Asian Pacific Journal of Cancer Prevention
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• v.15 no.11
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• pp.4449-4454
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• 2014

Aim: Helicobacter pylori (H. pylori) have been considered as a risk factor for many cancers. We conducted this meta-analysis to clarify the association between H. pylori infection and the risk of pancreatic cancer. Methods: We searched the Medicine/Pubmed and Embase databases, studies about the association between H. pylori infection and pancreatic cancer published up to Jan.2014 were included. Finally, a total of 9 studies were used for this a meta-analysis. The odds ratios (ORs) and 95% confidence interval (95%CI) of H. pylori infection on pancreatic cancer with respect to control groups were evaluated. Two authors independently assessed the methodological quality and extracted data. This meta-analysis was conducted using software, state (version 12.0) to investigate heterogeneity among individual studies and to summarize the studies. Using the fixed-effects or random-effects model, depending on the absence or presence of significant heterogeneity. Sensitivity analysis was performed to assess the influence of each individual study on the pooled ORs by omitting a single study each time. Publication bias was evaluated by funnel plot, using Egger's and Begg's tests. Results: There was no significant association between H. pylori infection and pancreatic cancer risk in the summary ORs,(OR=1.06, 95%CI: 0.74-1.37) through the random-effect method, but heterogeneity among studies was significant ($I^2$=58.9%), so we put the studies into two subgraphs (eastern and western). The results about western (OR=1.14 95%CI:0.89, 1.40) showed heterogeneity among the western countries of $I^2$=6.6%, with no significant association between Hp+ and pancreatic cancer, but the eastern countries (OR=0.62, 95%CI:0.49, 0.76), $I^2$=0, suggested that decreasing pancreas-cancer risk in subjects with Hp+ infection. Simultaneously, 7 studies examined CagA+ strains was (OR=0.84 95%CI:0.63, 1.04), $I^2$=36% with the random-effect method, subgraphs indicated that CagA+ could decrease the risk of pancreatic cancer in the eastern subjects (OR=0.66, 95%CI:0.52-0.80), but the association was not statistically significant in the western subjects (OR=0.95, 95%CI:0.73, 1.16). Conclusion: Hp+ and CagA+ infection are associated with a decreased risk of pancreatic cancer in eastern populations but have no significant associations in western countries.

• The Journal of Society for e-Business Studies
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• v.21 no.2
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• pp.1-22
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• 2016

News contents has been collected, selected, edited and sometimes distorted by the news recommendation mechanisms of online portals in nowadays. Prior studies had not confirmed the consensus of newsworthiness, and they had not tried to empirically validate the impacts of newsworthiness on audience reactions. This study challenged to summarize the concepts of newsworthiness and validate the impact of representativeness of both editor's and audience's perspective on audience reactions as perceived news quality, trust on news portal, perceived usefulness, service satisfaction, loyalty, continuous usage intention, and word-of-mouth intention by adopting the representativeness heuristics method and information adoption model. 357 valid data had been collected using a scenario survey method. Subjects in each groups are exposed by 3 news recommendation mechanisms: 1) the time-priority news exposure mechanism (control group), 2) the reference-score-based news recommendation mechanism (a single treatment group), and 3) the major-news-priority exposure mechanism sorting by the reference scores made by peer audiences (the mixed treatment group). Data had been analyzed by the MANOVA and PLS method. MANOVA results indicate that only mixed method of both editor and audience recommendation mechanisms impacts on perceived news quality and trust. PLS results indicate that perceived news quality and trust could significantly affect on the perceived usefulness, service satisfaction, loyalty, continuance usage, and word-of-mouth intention. This study would contributions to empathize the role of information technology in media industry, to conceptualize the news value in the balanced views of both editors and audiences, and to empirically validate the benefits of news recommendation mechanisms in academy. For practice, the results of this study suggest that online news portals would be better to make mixed news recommendation mechanisms to attract audiences.

• Journal of Korean Society for Atmospheric Environment
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• v.32 no.6
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• pp.575-582
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• 2016

Seoul city has high population density as well as high traffic congestion, which are vulnerable to exposure of environmental pollutions caused by car traffic. However, recent studies are only on local regions about road traffic and air pollution or health effect of road traffic on residents. Thus, comprehensive study data are needed in terms of overall Seoul regions. In this study utilized the nitrogen dioxide concentration through the national air pollution monitoring network data, 2012 to 2013. It also divided regions into high and low exposure districts via the Origin destination data developed by the Korea transport institute to quantify and evaluate the effect of transport policies and analyzed a correlation of asthma symptoms with high and low exposure districts through raw data of community health survey from the Korea centers for disease control and prevention. Based on the collected data, the pearson's correlation analysis was conducted between air pollution substance concentration and high exposure district and multiple logistic regression analysis was conducted to determine the effect of traffic environment and factors on asthma symptoms of residents. Accordingly, the following results were derived. First, the high exposure district was higher concentrations of nitrogen dioxide ($NO_2$) as per time compared to those of the low exposure district (p<0.01). Second, analysis on correlation between average daily environmental concentration in the air pollution monitoring network and road traffic showed that nitrogen dioxide had a significant positive correlation (p<0.01) with car traffic and total traffic as well as with truck traffic (p<0.05) statistically. Third, an adjusted odds ratio about asthma doctor's diagnosis in the high and low exposure districts was analyzed through the logistic regression analysis. With regard to an adjusted model 2 (adjusted gender, age, health behavior characteristics, and demographic characteristics) odds ratio of asthma doctor's diagnosis in the high exposure district was 1.624 (95% CI: 1.269~2.077) compared to that of the low exposure district, which was significant statistically (p<0.001).

• The Korea Journal of Herbology
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• v.22 no.2
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• pp.25-33
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• 2007

Objectives : Oriental pear was used as treatment of asthma, control of blood pressure, diabetes in oriental medicine. The aim of this study was to observe the effects of Phenolic compound extracted from pear and herbal drugs to treat asthma. Methods : In order to study the effect of oral administration of phenolic compound extracted from pear and herbal drugs(Platycodon grandiflorum, Prunus armeniaca) on allergic asthma, mice were pre-treated by oral administration of the solution before antigen sensitization four times for 8 days. 2 days later, mice were actively sensitized with a subcutaneous injection of ovalbumin and 13 days later, they were provoked with ovalbumin aerosols. The animals were divided into four groups; Saline, orally administered saline. PC-A, orally administered Phenolic compound extracted from pear peel 10mg/kg/ml. PC-B, orally administered Phenolic compound extracted from pear peel and flesh 10mg/kg/ml. PC-C, orally administered pear 10m/kg/ml, Platycodon grandiflorum 24.4 mg/kg/ml and Prunus armeniaca 33.3 mg/kg/ml. Serum level of IgE, IL-4, cell numbers in the bronchoalveolar lavage fluid(BALF), and in vitro isometric contractile responses of the isolated tracheal smooth muscle(TSM) to acetylcholine(ACh, $0.1-1000{\mu}M$), KCl were measured. Results : Contractile responses of TSM to ACh were decreased in PC-A group at Ach 0.1, 0.3, 1 ${\mu}M$, decreased in PC-B at 0.1 ${\mu}M$ and decreased in PC-C at 0.1, 0.3, 1, 10, 30 ${\mu}M$. The maximal contractile response of TSM to KCl was decreased in PC-C group, The cell numbers of eosinophil in BALF were decreased in PC-C group, and those of macrophages in BALF were decreased in PC-A and PC-C group. Interleukin-4 in BALF was decreased in PC-A, PC-B, PC-C group. Conclusion : Based on the above results it is assumed that oral administration of phenolic compound extracted from pear and herbal drugs can help the treatment of deficiency allergic Asthma.

• 제어로봇시스템학회:학술대회논문집
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• 1991.10b
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• pp.1649-1654
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• 1991

In 1995 the VSOP satellite, which is called MUSES-B in Japan, will be launched under the VLBI Space Observatory Programme(VSOP) promoted by ISAS(Institute of Space and Astronautical Science) of Japan. We are now developing the GPS Receiver(GPSR) and On-board Orbit Determination System. This paper describes the GPS(Global Positioning System), VSOP, GPSR(GPS Receiver system) configuration and the results of the GPS system analysis. The GPSR consists of three GPS antennas and 5 channel receiver package. In the receiver package, there are two 16 bits microprocessing units. The power consumption is 25 Watts in average and the weight is 8.5 kg. Three GPS antennas on board enable GPSR to receive GPS signals from any NAVSTARs(GPS satellites) which are visible. NAVSATR's visibility is described as follows. The VSOP satellite flies from 1, 000 km to 20, 000 km in height on the elliptical orbit around the earth. On the other hand, the orbit of NAVSTARs are nearly circular and about 20, 000 km in height. GPSR can't receive the GPS signals near the apogee, because NAVSTARs transmit the GPS signals through the NAVSTAR's narrow beam antennas directed toward the earth. However near the perigee, GPSR can receive from 12 to 15 GPS signals. More than 4 GPS signals can be received for 40 minutes, which are related to GDOP(Geometric Dillusion Of Precision of selected NAVSTARs). Because there are a lot of visible NAVSTARs, GDOP is small near the perigee. This is a favorqble condition for GPSR. Orbit determination system onboard VSOP satellite consists of a Kalman filter and a precise orbit propagator. Near the perigee, the Kalman filter can eliminate the orbit propagation error using the observed data by GPSR. Except a perigee, precise onboard orbit propagator propagates the orbit, taking into account accelerations such as gravities of the earth, the sun, the moon, and other acceleration caused by the solar pressure. But there remain some amount of calculation and integration errors. When VSOP satellite returns to the perigee, the Kalman filter eliminates the error of the orbit determined by the propagator. After the error is eliminated, VSOP satellite flies out towards an apogee again. The analysis of the orbit determination is performed by the covariance analysis method. Number of the states of the onboard filter is 8. As for a true model, we assume that it is based on the actual error dynamics that include the Selective Availability of GPS called 'SA', having 17 states. Analytical results for position and velocity are tabulated and illustrated, in the sequel. These show that the position and the velocity error are about 40 m and 0.008 m/sec at the perigee, and are about 110 m and 0.012 m/sec at the apogee, respectively.

• Journal of Korea Water Resources Association
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• v.36 no.3 s.134
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• pp.345-363
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• 2003

From the General Circulation Models(GCMs), it is known that the increases of concentrations of greenhouse gases will have significant implications for climate change in global and regional scales. The GCM has an uncertainty in analyzing the meteorologic processes at individual sites and so the 'downscaling' techniques are used to bridge the spatial and temporal resolution gaps between what, at present, climate modellers can provide and what impact assessors require. This paper describes a method for assessing local climate change impacts using a robust statistical downscaling technique. The method facilitates the rapid development of multiple, low-cost, single-site scenarios of daily surface weather variables under current and future regional climate forcing. The construction of climate change scenarios based on spatial regression(transfer function) downscaling and on the use of a local stochastic weather generator is described. Regression downscaling translates the GCM grid-box predictions with coarse resolution of climate change to site-specific values and the values were then used to perturb the parameters of the stochastic weather generator in order to simulate site-specific daily weather values. In this study, the global climate change scenarios are constructed using the YONU GCM control run and transient experiments.

• Journal of the Korea Concrete Institute
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• v.26 no.2
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• pp.143-150
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• 2014

To avoid abrupt torsional failure due to concrete crushing before yielding of torsional reinforcement and control the diagonal crack width, design codes specify the limitations on the yield strength of torsional reinforcement of RC members. In 2012, Korean Concrete Institute design code increased the allowable maximum yield strength of torsional reinforcement from 400 MPa to 500 MPa based on the analytical and experimental research results. Although there are many studies regarding the shear behavior of RC members with high strength stirrups, limited studies of the RC members regarding the yield strength of torsional reinforcement are available. In this study, twelve RC beams having different yield strength of torsional reinforcement and compressive strength of concrete were tested. The experimental test results indicated that the torsional failure modes of RC beams were influenced by the yield strength of torsional reinforcement and the compressive strength of concrete. The test beams with normal strength torsional reinforcement showed torsional tension failure, while the test beams with high strength torsional reinforcement greater than 480 MPa showed torsional compression failure. Therefore, additional analytical and experimental works on the RC members subjected to torsion, especially the beams with high strength torsional reinforcement, are needed to find an allowable maximum yield strength of torsional reinforcement.

• Journal of the Korean Society of Food Science and Nutrition
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• v.45 no.5
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• pp.634-641
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• 2016

The objective of this research was to investigate the in vivo effects of treatment with mulberry extract complex (MEC) on cartilage degeneration and pain severity in an experimental model of rat degenerative arthritis. Monosodium iodoacetate ($2mg/50{\mu}L$) was injected into right knee joints of rats, followed by administration of MEC for 8 weeks at 400 mg/kg or 800 mg/kg of body weight. The experimental data show that treatment with MEC inhibited degradation of glycosaminoglycan and collagen in cartilage. On the other hand, concentrations of cartilage oligomeric matrix protein, C-terminal telopeptide-2, matrix metalloproteinase (MMP)-2, MMP-9, and MMP-13 in serum decreased in comparison with the control. The MEC at all dose levels could inhibit formation of xylene-induced ear edema. In this study, MEC demonstrated significant anti-arthritis activity, which is required for improvement of degenerative arthritis. Based on these results, MEC may be employed for the development of new health foods to ease symptoms of degenerative arthritis.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.12 no.3
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• pp.139-148
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• 2000

In this paper, the interaction of oblique incident waves with a bottom-mounted and fluid-filled flexible membrane structure is investigated in the frame of linear hydro-elastic theory. The static shape of a membrane structure containing the fluid of a specific density is initially unknown and must be calculated before the hydrodynamic analysis. To solve hydrodynamic problem, the fluid domain is divided into the inner and outer region. The inner solution based on discrete membrane dynamic model and simple-source distribution over the entire fluid boundaries is matched to the outer solution ba~ed on an eigenfunction expansion method. The numerical results were compared to a series of Ohyama's experimental results. The measured reflection and tran¬smission coefficients reasonably follow the trend of predicted values. Using the computer program developed, the performance of a bottom-mounted and fluid-filled flexible membrane strocture is tested with various system parameters (membrane shape, internal pressure, density ratio) and wave characteristics (wave frequencies, incident wave angle). It is found that a bottom-mounted and fluid-filled flexible membrane structure can be an effel;tive wave barrier if properly designed.

• Journal of the Korean Society of Clothing and Textiles
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• v.32 no.12
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• pp.1825-1836
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• 2008

Many applications in computer graphics require complex and highly detailed models. However it is often desirable to use approximations in place of excessively detailed models in order to control the processing time. Thus, we aim to develop a notion of optimal matrix to simplify surface which can rapidly obtain the high quality 2D patterns flattening 3D surface as follows. Firstly, two 3D bodies are modeled based on existing Size Korea data. Secondly, each model is divided by shell and block for its pattern draft. Thirdly, each block is flattened by grid and bridge method. Finally, we selected the optimal matrix and demonstrated the efficiency and quality of the proposed method. This proposed approach accommodates surfaces with darts, which are commonly used in the clothing industry to reduce the deformation of surface forming and flattening. The resulting optimal matrix could be an initiation of standardization for pattern flattening. It is expected that this method could facilitate much better approximation in both efficiency and precision.