• 대한안전경영과학회지
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• 제11권4호
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• pp.193-199
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• 2009

Recently, an industrial production-distribution planning problem has been widely investigated in Supply Chain Management(SCM). One of the key issues in the current SCM research area is reverse logistics network. This study have developed a simulation model for the reverse logistics network. The simulation model analysis reverse logistics network issues such as inventory policy, manufacturing policy, transportation mode, warehouse assignment, supplier assignment. Computational experiments using commercial simulation tool ARENA show that the real problems. The model can be used to decide an appropriate production-distribution planning problem in the research area.

• Asian-Australasian Journal of Animal Sciences
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• 제8권6호
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• pp.533-555
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• 1995

Direct-fed microbials (DFM) have been used to enhance milk production in lactating cattle and to increase feed efficiency and body weight gain in growing ruminants. Primary microorganisms that have been used as DFM for ruminants are fungal cultures including Aspergillus oryzae and Saccharomyces cerevisiae and lactic acid bacteria such as Lactobacillus or Streptococcus. Attempts have been made to determine the basic mechanisms describing beneficial effects of DFM supplements. Various modes of action for DFM have been suggested including : stimulation of ruminal microbial growth, stabilization of ruminal pH, changes in ruminal microbial fermentation pattern, increases in digestibility of nutrients ingested, greater nutrient flow to the small intestine, greater nutrient retention and alleviation of stress, however, these responses have not been observed consistently. Variations in microbial supplements, dosage level, production level and age of the animal, diet and environmental condition or various combinations of the above may partially explain the inconsistencies in response. This review summarizes production responses that have been observed under various conditions with supplemental DFM and also corresponding modification of ruminal fermentation and other changes in the gastrointestinal tract of ruminant animals.

• International Journal of Fluid Machinery and Systems
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• 제10권3호
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• pp.264-273
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• 2017

In order to be able to predict the maximum Annual Energy Production (AEP) for tidal power plants, an AEP optimization tool based on Evolutionary Algorithms was developed by ANDRITZ HYDRO. This tool can simulate all operating modes of the units (bi-directional turbine, pump and sluicing mode) and provide the optimal plant operation that maximizes the AEP to the control system. For the Swansea Bay Tidal Power Plant, the AEP optimization evaluated all different hydraulic and operating concepts and defined the optimal concept that led to a significant AEP increase. A comparison between the optimal plant operation provided by the AEP optimization and the full load operating strategy is presented in the paper, highlighting the advantage of the method in providing the maximum AEP.

• 대한산업공학회지
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• 제24권1호
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• pp.157-165
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• 1998

This paper considers the single-product production and transportation problem with discrete time, dynamic demand and finite time horizon, an extension of classical dynamic lot-sizing model. In the model, multiple freight container types are allowed as the transportation mode and each order (product) placed in a period is shipped immediately by containers in the period. Moreover, each container has type-dependent carrying capacity restriction and at most one container type is allowed in each shipping period. The unit freight cost for each container type depends on the size of its carrying capacity. The total freight cost is proportional to the number of each container type employed. Such a freight cost is considered as another set-up cost. Also, it is assumed in the model that production and inventory cost functions are dynamically concave and backlogging is not allowed. The objective of this study is to determine the optimal production policy and the optimal transportation policy simultaneously that minimizes the total system cost (including production cost, inventory holding cost, and freight cost) to satisfy dynamic demands over a finite time horizon. In the analysis, the optimal solution properties are characterized, based on which a dynamic programming algorithm is derived. The solution algorithm is then illustrated with a numerical example.

• KSBB Journal
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• 제4권3호
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• pp.241-245
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• 1989

Streptomyces erythreus의 포자를 다공성의 celite를 담체로 이용하여 미세구멍조직내에 흡착 후 배양하여 얻은 균사 증식 담체를 erythromycin의 발효에 응용하였다. 이때 균사체는 담체의 내부에서부터 포자가 발아하여 담체 표면으로 성장되어 나왔기 때문에 부착성이 강하고 매우 안정한 biofilm growth를 보여 주었다. 발효시 배지중의 com steep liquor의 양을 0.8g/L 첨가하여 인산원의 농도를 40mg $KH_2PO_4/L 정도로 하였을 때 항생제 비생산 속도는 최대값 2,898$\mu$g/g.cell.hr로서 인산원이 제한되지 않은 배지에서 얻은 비생산속도 557$\mu$g/g.cell.hr보다 약 4배의 증가효과를 보였다. 유동층 반응기를 이용한 연속 발효 공정에서도 인산원의 제한에 의하며 세포의 항생제 합성 활성은 약 600시간 이상 유지 되었다.

• Environmental Engineering Research
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• 제24권3호
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• pp.521-528
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• 2019

Electrochemical method was used for the fracturing flow-back fluid treatment in Guangyuan oilfield. After performing electrolysis, we found that the amount of $H_2$ gas produced by electrode was closely related to the combination mode of electrodes and electrode materials. Using an aluminium electrode resulted in a large $H_2$ production of each electrode combination, whereas inert anode and cathode materials resulted in low $H_2$ production. Then, the relationship between the gas production of $H_2$ and the treatment efficiency of fracturing flow-back fluid in Guangyuan oilfield was studied. Results showed that the turbidity removal and decolourisation rates of fracturing flow-back fluid were high when $H_2$ production was high. If the $H_2$ production of inert electrode was large, the energy consumption of this inert electrode was also high. However, energy consumption when an aluminium anode material was used was lower than that when the inert electrode was used, whereas the corresponding electrode combination production of $H_2$ was larger than that of the inert electrode combination. When the inert electrode was used as anode, the gas production type was mainly $O_2$, and $Cl_2$ was also produced and dissolved in water to form $ClO^-$. $H_2$ production at the cathode was reduced because $ClO^-$ obtained electrons.

• 품질경영학회지
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• 제50권1호
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• pp.125-138
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• 2022

Purpose: Failure Mode and Effect Analysis (FMEA) is a widely utilized technique to measure product reliability by identifying potential failure modes. Even though FMEA techniques have been studied, the form of Risk Priority Number (RPN) used to evaluate risk priority in FMEA is still questionable because of its shortcomings. In this study, we suggest common RPN(cRPN) to resolve shortcomings of the traditional RPN and show the extensibility of cRPN. Methods: We suggest cRPN which is based on Cobb-Douglas production function, and represent the various application on weighting risk factors, weighted RPN in a mathematical way, and show the possibility of statistical approach. We also conduct numerical study to examine the difference of the traditional RPN and cRPN as well as the potential application from the analysis on marginal effects of each risk factor. Results: cRPN successfully integrates previously suggested approaches especially on the relative importance of risk factors and weighting RPN. Moreover, we analyze the effect of corrective actions in terms of econometric analysis using cRPN. Since cRPN is rely on the reliable mathematical model, there would be numerous applications using cRPN such as smart factory based on A.I. techniques. Conclusion: We propose a reliable mathematical model of RPN based on Cobb-Douglas production function. Our suggested model, cRPN, resolves various shortcomings such as consideration of the relative importance, the effect of combinations among risk factors. In addition, by adopting a reliable mathematical model, quantitative approaches are expected to be applied using cRPN. We find that cRPN can be utilized to the field of industry because it is able to be applied without modifying the entire systems or the conventional actions.

• Journal of Microbiology and Biotechnology
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• 제32권3호
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• pp.378-386
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• 2022

Scenedesmus obliquus ABC-009 is a microalgal strain that accumulates large amounts of lutein, particularly when subjected to growth-limiting conditions. Here, the performance of this strain was evaluated for the simultaneous production of lutein and biofuels under three different modes of cultivation - photoautotrophic mode using BG-11 medium with air or 2% CO₂ and heterotrophic mode using YM medium. While it was found that the highest fatty acid methyl ester (FAME) level and lutein content per biomass (%) were achieved in BG-11 medium with CO₂ and air, respectively, heterotrophic cultivation resulted in much higher biomass productivity. While the cell concentrations of the cultures grown under BG-11 and CO₂ were largely similar to those grown in YM medium, the disparity in the biomass yield was largely attributed to the larger cell volume in heterotrophically cultivated cells. Post-cultivation light treatment was found to further enhance the biomass productivity in all three cases and lutein content in heterotrophic conditions. Consequently, the maximum biomass (757.14 ± 20.20 mg/l/d), FAME (92.78 ± 0.08 mg/l/d), and lutein (1.006 ± 0.23 mg/l/d) productivities were obtained under heterotrophic cultivation. Next, large-scale lutein production using microalgae was demonstrated using a 1-ton open raceway pond cultivation system and a low-cost fertilizer (Eco-Sol). The overall biomass yields were similar in both media, while slightly higher lutein content was obtained using the fertilizer owing to the higher nitrogen content.

• Journal of Microbiology and Biotechnology
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• 제12권2호
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• pp.273-278
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• 2002

Two-step fed-batch fermentations were carried out to overproduce Bacillus licheniformis maltogenic amylase (BLMA) in recombinant Escherichia coli. The first step was to increase the cell mass by controlling the feeding of a glucose solution, while the second step was designed to improve the amylase expression efficiency by supplementing organic nitrogen sources. The linear gradient feeding method was successfully adopted to maintain the glucose concentration below 0.2 g/l during the fed-batch mode, as effectively minimizing acetic acid formation. When the dissolved oxygen (DO) level became limiting, an accumulation of acetic acid and drastic decrease in specific BLMA productivity were observed. Glucose and organic nitrogen sources consisting of yeast extract and casein hydrolysate were simultaneously supplied in the pH-stat mode to further increase the specific BLMA expression efficiency. An organic nitrogen source consisting of 200 g/1 yeast extract and 100 g/1 casein hydrolysate was found to be the best among the various combinations tested. The feeding of an organic nitrogen source in the second-step fed-batch period was highly beneficial in enhancing the BLMA production. The optimized two-step fed-batch culture resulted in 78 g/l maximum dry cell mass and 443 U/ml maximum BLMA activity, corresponding to 1.5-fold increase in the dry cell mass and 3.7-fold enhancement in BLMA production, compared with the simple fed-batch fermentation.

• 한국축산시설환경학회지
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• 제14권2호
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• pp.75-80
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• 2008

High concentration of $NH_3$, $CO_2$, and lots of dust are found in modern densely raising stall system, as results, they provide a negative influence on animal and lamer health, and production ability. Therefore, it is necessary to keep clean the inside of stall air to increase the productivity. A wet type air cleaner has been developed to clean the stall air. The work principle is that the inside air are sucked through the fan, and the rotating discs make a water into a fineness spray and blows into the stall. The spray can take the dust, $NH_3$, and odor from the stall inside air and give back to the circulating water, which can be refreshed in 2 hours interval. In the Present study, we measured the $NH_3$, dust, odor, temperature and humidity in a swine stall that were installed two wet air cleaners with 700 fattening swine with on-mode and off-mode of wet air cleaners. In fall, the concentrations of $NH_3$ in off-mode stall were maximum 24 ppm and minimum 16 prm, and the average was 18.2 ppm. However in on-mode stall the $NH_3$ concentrations were maximum 7ppm and minimum 1ppm, and the average was 2.7ppm. The concentration of $NH_3$ in on-mode was 74% lower than off-mode stall. Odor was measured by olfactometer. In the off-mode stall, the odor unit was 3,800 OU/$m^3$, but in the on-mode stall the odor unit was 2,100 OU/$m^3$ Odor removal efficiency was about 45% in on-mode stall. The dust measure was divided into 3 categories, $PM_{10}$, $PM_{2.5}$ and $PM_{1.0}$. Whereas the $PM_{10}$ showed no significant differences between the tests, $PM_{2.5}$ and $PM_{1.0}$ in the fine particle range reduced remarkably in the on-mode.