• 제목/요약/키워드: Mixed effects model

검색결과 487건 처리시간 0.032초

Analysis of shallow footings rested on tensionless foundations using a mixed finite element model

  • Lezgy-Nazargah, M.;Mamazizi, A.;Khosravi, H.
    • Structural Engineering and Mechanics
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    • 제81권3호
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    • pp.379-394
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    • 2022
  • Shallow footings usually belonged to the category of thick plate structures. For accurate analysis of thick plates, the contribution of out-of-plane components of the stress tensor should be considered in the formulation. Most of the available shallow footing models are based on the classical plate theories, which usually neglect the effects of the out-of-plane stresses. In this study, a mixed-field plate finite element model (FEM) is developed for the analysis of shallow footings rested on soil foundations. In addition to displacement field variables, the out-of-plane components of the stress tensor are also assumed as a priori unknown variables. For modeling the interaction effect of the soil under and outside of the shallow footings, the modified Vlasov theory is used. The tensionless nature of the supporting soil foundation is taken into account by adopting an incremental, iterative procedure. The equality requirement of displacements at the interface between the shallow footing and soil is fulfilled using the penalty approach. For validation of the present mixed FEM, the obtained results are compared with the results of 3D FEM and previous results published in the literature. The comparisons show the present mixed FEM is an efficient and accurate tool for solving the problems of shallow footings rested on subsoil.

집단 약동학 모형에 대한 통계학적 고찰 (A Statistical Approach to the Pharmacokinetic Model)

  • 이은경
    • 응용통계연구
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    • 제23권3호
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    • pp.511-520
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    • 2010
  • 약동학 모형은 약동학 모수들의 복잡한 비선형형태의 함수로 복잡한 미분방정식의 형태로 나타나기도 한다. 집단 약동학은 약동학 모형에서 약동학 모수들의 개인 간 차이를 나타내기 위해 이를 랜덤효과로 가정하므로 비선형 혼합 효과 모형이 된다. 본 논문에서는 임상약리학에서 약동학적 특징을 설명하기 위해 사용하는 집단 약동학 모형에 대한 통계학적 고찰을 해 본다. 또한 실제 임상자료를 이용하여 집단 약동학 모형을 적용하여 분석해 봄으로써 통계적 의미를 살펴본다.

컨조인트 분석에서 효율적인 문항 설계 (Efficient designs in conjoint analysis)

  • 정종희;임용빈
    • 품질경영학회지
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    • 제46권1호
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    • pp.27-38
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    • 2018
  • Purpose: A large number of attributes with mixed levels are often considered in the conjoint analysis. In the cases where attributes have two or three levels, we research on the efficient design of survey questionnaire to estimate all the main effect and two factor interaction effects with a reasonable size of it. Methods: To reduce the number of questions in a questionnaire, the balanced incomplete block mixed level factorial design with minimum aberration was proposed by Lim and Chung (2016). Based on the number of questions and that of the respondents in that design, D-optimality criterion is adopted to find efficient designs where the main effect and two factor interaction effects are estimated. Results: The list of the number of questions and that of the respondents in efficient designs for survey questionnaire are recommended based on the D-efficiency of each design and the proposed selection criteria for the number of both questions and the respondents. By analyzing all the respondents survey data generated by the simulation study, we find the proper model. Conclusion: The proposed methods of designing survey questionnaires seem to perform well in the sense that how often the proper model is found in a simulation study where all the respondents survey data are generated by the simulation model.

Likelihood-Based Inference on Genetic Variance Component with a Hierarchical Poisson Generalized Linear Mixed Model

  • Lee, C.
    • Asian-Australasian Journal of Animal Sciences
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    • 제13권8호
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    • pp.1035-1039
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    • 2000
  • This study developed a Poisson generalized linear mixed model and a procedure to estimate genetic parameters for count traits. The method derived from a frequentist perspective was based on hierarchical likelihood, and the maximum adjusted profile hierarchical likelihood was employed to estimate dispersion parameters of genetic random effects. Current approach is a generalization of Henderson's method to non-normal data, and was applied to simulated data. Underestimation was observed in the genetic variance component estimates for the data simulated with large heritability by using the Poisson generalized linear mixed model and the corresponding maximum adjusted profile hierarchical likelihood. However, the current method fitted the data generated with small heritability better than those generated with large heritability.

해양-대기 결합수치모형을 이용한 ENSO 연구 (An Ocean - Atmosphere Coupled Model for the Study of ENSO)

  • 안중배
    • 한국환경과학회지
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    • 제3권2호
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    • pp.129-140
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    • 1994
  • An intermediate atmosphere-ocean coupled model appropnate for the study of El Nino has been developed. The model is not only economic to use but also contains several most important physical processes. The geometrical effects which were not confided in the previous intermediate model study of Ahn (1990), are included in the model for more realistic simulation of the event. The results show that the individual models respond appropriately to the given boundary conditions. At the same time, in the coupled model experiment, ENSO-like oceanic and atmospheric anomalies are also well simulated under an external triggering similar to the initiation forcing of ENSO. It is expected that this type of model can be effectively used for the. study and simulation of El Nido. More improvement of modeling may be Possible after inclusion of subsequent processes such as inclusion of ocean mixed layer dynamics.

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Solid State Drive(SSD)에 대한 가속열화시험 데이터 모델링 및 분석 (Modeling and Analysis of Accelerated Degradation Testing Data for a Solid State Drive (SSD))

  • 문병민;최영진;지유민;이용중;이근우;나한주;양중섭;배석주
    • 한국신뢰성학회지:신뢰성응용연구
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    • 제18권1호
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    • pp.33-39
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    • 2018
  • Purpose: Accelerated degradation tests can be effective in assessing product reliability when degradation leading to failure can be observed. This article proposes an accelerated degradation test model for highly reliable solid state drives (SSDs). Methods: We suggest a nonlinear mixed-effects (NLME) model to degradation data for SSDs. A Monte Carlo simulation is used to estimate lifetime distribution in accelerated degradation testing data. This simulation is performed by generating random samples from the assumed NLME model. Conclusion: We apply the proposed method to degradation data collected from SSDs. The derived power model is shown to be much better at fitting the degradation data than other existing models. Finally, the Monte Carlo simulation based on the NLME model provides reasonable results in lifetime estimation.

선형혼합모형을 활용한 생물학적 동등성 분석 (Bio-Equivalence Analysis using Linear Mixed Model)

  • 안형미;이영조;유경상
    • 응용통계연구
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    • 제28권2호
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    • pp.289-294
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    • 2015
  • 생동성 시험과 같은 임상약리학분야의 연구는 일반적으로 한 개체 내에서 반복하여 측정된 자료구조를 사용하므로 선형혼합모형을 이용하여 분석하는 것이 보편적이다. 이러한 모형에서 랜덤효과는 개체 내 관측 자료 사이의 상관관계를 설명하고, 공분산행렬은 개체-내 변동을 설명한다. 생동성 분석은 두 약물의 약동학적 변수인 Cmax와 AUC의 기하평균비에 대한 90% 신뢰구간이 동등성 한계인 [0.8, 1.25] 범위에 드는지 알아보는 분석으로, 고정효과에는 시기, 순서군, 치료효과를, 랜덤효과에는 개체효과를 가지는 선형혼합모형을 이용하여 분석한다. 이러한 분석이 적용된 실제 예를 살펴보기 위하여 레보플록사신 연구의 자료를 활용하였다.

모델을 이용한 음식물퇴비 혼합토양에서의 Pb 흡착 및 이동성 평가 (The assessment of the adsorption and movement of Pb in mixed soil with food compost using model)

  • 주유연;강선홍
    • 상하수도학회지
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    • 제22권2호
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    • pp.251-257
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    • 2008
  • Food compost, having a higher organic contents than soil, could be an alternative material to prevent the proliferation of heavy metals contamination in soil. In this study we used a convection-dispersion local equilibrium sorption model(CDE) and a two-site non-equilibrium sorption model to find the effects on the adsorption and transportation of Pb by mixing food compost with soil and we also tried to find the effect of velocity and concentration of the injected solution on the characteristics of Pb. We measured Pb concentrations in injection-liquid and in effluent, and then applied them to CXTFIT program. As a result of column experiments, some parameters(D, R, ${\beta}$, ${\omega}$) used in two-site non-equilibrium adsorption model were obtained. Characteristics of Pb adsorption and transport were analyzed using the parameters(D, R, ${\beta}$, ${\omega}$) obtained from the CXTFIT program, We could know that mixed soil with food compost showed a higher adsorption capacity from the retardation factor(R) calculated from the breakthrough curve(BTCs) of Pb. Rs of soil and mixed soil are 20.45, 37.45 respectively, indicating that the adsorption and the transportation characteristics could be accessed quantitatively by using of two-site non-equilibrium adsorption model.

불균형 자료에서 AIC를 이용한 선형혼합모형 선택법의 효율에 대한 모의실험 연구 (Simulation Study on Model Selection Based on AIC under Unbalanced Design in Linear Mixed Effect Models)

  • 이용희
    • 응용통계연구
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    • 제23권6호
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    • pp.1169-1178
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    • 2010
  • 본 논문은 불균형 자료에서 선형혼합모형에 적용되는 Akaike Information Criterion(AIC)의 효율에 대한 연구이다. Vaida와 Balanchard (2005)에 의해 제안된 cAIC(conditional AIC)는 mAIC(marginal AIC)가 임의효과의 예측에 대한 불확실성을 모형선택에서 반영하지 못하는 단점을 극복할 수 있는 방법이다. cAIC에 대한 이론적인 성질과 확장은 Liang 등 (2008)과 Greven과 Kneib (2010)에 의하여 연구되었다. cAIC의 형태는 자료의 구조에 영향을 받지는 않지만 선형혼합모형에서 모수의 추정 효율은 자료의 불균형의 정도에 따라 많은 영향을 받는 것이 알려져 있다. 기존의 연구에서 실시한 모든 모의실험이 자료가 균형인 경우에만 실행되어 자료의 불균형이 AIC에 근거한 혼합모형 선택 방법의 효율에 어떤 영향을 미치는지 알려져 있지 않다. 본 논문은 자료의 불균형이 모형선택 방법의 효율에 미치는 영향을 모의실험을 통하여 알아보았다. 자료의 불균형이 심해짐에 따라 AIC에 근거한 모형선택방법은 복잡한 모형을 선택하는 경향이 낮아짐을 보였다.

Kinetic Study of pH Effects on Biological Hydrogen Production by a Mixed Culture

  • Jun, Yoon-Sun;Yu, Seung-Ho;Ryu, Keun-Garp;Lee, Tae-Jin
    • Journal of Microbiology and Biotechnology
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    • 제18권6호
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    • pp.1130-1135
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    • 2008
  • The effect of pH on anaerobic hydrogen production was investigated under various pH conditions ranging from pH 3 to 10. When the modified Gompertz equation was applied to the statistical analysis of the experimental data, the hydrogen production potential and specific hydrogen production rate at pH 5 were 1,182 ml and 112.5 ml/g biomass-h, respectively. In this experiment, the maximum theoretical hydrogen conversion ratio was 22.56%. The Haldane equation model was used to find the optimum pH for hydrogen production and the maximum specific hydrogen production rate. The optimum pH predicted by this model is 5.5 and the maximum specific hydrogen production rate is 119.6 ml/g VSS-h. These data fit well with the experimented data($r^2=0.98$).