• Korean Institute of Interior Design Journal
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• v.19 no.4
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• pp.90-98
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• 2010

This study intends to understand the change of the library's bookshelves shape, composition and arrangement based on the social-culture in each period. For this purpose, this study analyzes the morphological shift of the library's bookshelves and knowledge information focused on the history of western libraries from the ancient libraries to the modern public libraries before the 20th century. And the results are follows. 1) We can make sure that the changes of the library's bookshelves are based on the environmental factors like social cultural political factors and also understand that the knowledge information are developed based on the function which is decided by the needs of the times and the serious necessities of users. With this reason, the morphology and the function of the library's bookshelves have been changed. 2) The characters and meanings of the library's bookshelves are changed with the times from movable type to fixed type, from closing type to opening type, from privileged use to public use, from religious contents to general scientific contents. 3) The morphology of the library's bookshelves are shifted from cylindrical box to Chest type Press type and Lectern system, Stall system, Wall system and advanced to Mixed(Stall+Wall) system. 4) The construction and arrangement methods of the library's bookshelves are determined by the convenience and efficiency of the installation for the perusal environments as well as the regarding to the social-cultural factors. The arrangement criteria are determined by the security topics in the earlier stage, after that determined by the lightening topics and nowadays the access topics to the information. These analysis results are very useful to research the technology of the library's bookshelves to be changed continuously and also to forecast the morphology of the library's bookshelves can be planned in the spaces of the future libraries.

• Nutrition Research and Practice
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• v.9 no.1
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• pp.57-62
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• 2015

BACKGROUND/OBJECTIVES: The prevalence of atopic dermatitis in infants is increasing worldwide. However, the nutrient intake status of infants with atopic dermatitis has not been studied properly. This study was conducted to compare the nutrient intake status of infants in the weaning period with atopic dermatitis by feeding type. MATERIALS/METHODS: Feeding types, nutrient intake status and growth status of 98 infants with atopic dermatitis from age 6 to 12 months were investigated. Feeding types were surveyed using questionnaires, and daily intakes were recorded by mothers using the 24-hour recall method. Growth and iron status were also measured. RESULTS: The result showed that breastfed infants consumed less energy and 13 nutrients compared to formula-fed or mixed-fed infants (P < 0.001). The breastfed group showed a significantly lower intake rate to the Dietary Reference Intakes for Koreans than the other two groups (P < 0.001). In addition, they consumed less than 75% of the recommended intakes in all nutrients, except for protein and vitamin A, and in particular, iron intake was very low, showing just 18.7% of the recommended intake. There was no significant difference in growth by feeding type, but breastfed infants showed a significantly higher rate of iron deficiency anemia (P < 0.001). CONCLUSIONS: Continuous management programs should be prepared for breastfed infants with atopic dermatitis, who are in a period when rapid growth takes place and proper nutrient intake is essential.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.6
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• pp.187-196
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• 2017

In using lecture evaluation methods to improve the quality of education, most universities need to reflect the changes in the educational environment. The transformation of university education into a mixed learning environment blending face-to-face education and online education necessitates the development of appropriate lecture evaluation items. For this purpose, we analyzed the items and the factor analysis for the students of C university in Daejeon. The primary data were carried out with 47 measurement items in 10 domains, such as planning and preparation of lectures, which were found through previous research analysis. Secondary data were validated by using the items confirmed through analysis of preliminary test data. The study results showed that 20 items including six domains such as planning and preparation of lectures, learning materials, learning tasks, instruction media, online course test and grades were derived. These study results suggest that universities lectures should be evaluated to ensure improvement.

• Women's Health Nursing
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• v.22 no.4
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• pp.221-232
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• 2016

Purpose: The purpose of this study was to examine the applicability of a flipped learning course in Women's Health Nursing for nursing students. Methods: A total of 200 senior nursing students participated in flipped learning class of pregnancy, delivery and postpartum area, which included team-based learning and self-reflection for 8 weeks. One group pre-post test design was adopted and the changes in learning motivation and satisfaction were examined. In addition, reflective journals of the students were analyzed by making a qualitative content analysis. Results: Students showed a significant increase in score of learning motivation in the posttest (t=-4.47, p<.001). They had a mean of 3.90 in learning satisfaction out of possible five points. As a result of content analysis, three themes were selected: 'Improved attitude toward active learning', 'Burden caused by excessive workload', and 'Valuing to the team-based activity' To be specific, six sub-themes were selected, with three positive and three negative categories: 'improved class attention and understanding', 'positive class participation by preparing lessons in advance', 'peer interactions through discussion', 'A lot of time and effort consuming', 'stress caused by the burden of preparing lessons', and 'difficulties in cooperative activities'. Conclusion: This study supports and confirms that the flipped learning can be a creative instructional model of positive teaching-learning strategy in clinical nursing courses to enhance students' learning motivation.

• Asian-Australasian Journal of Animal Sciences
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• v.33 no.3
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• pp.465-479
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• 2020

Objective: This study performed a meta-analysis of published trials to determine the effects of zinc on the immune response and production performance of broilers. Methods: A database was built from published literature regarding the addition of zinc forms or doses and their relation to the immune response and production performance of broilers. Different doses or forms of zinc were identified in the database. The recorded parameters were related to the immune response and production performance. The database contained a total of 323 data points from 41 studies that met the criteria. Then, the data were processed for a meta-analysis using a mixed model methodology. The doses or different forms of zinc were considered fixed effects, different studies were treated as random effects, and p-values were used as the model statistics. Results: An increase in zinc dose increased (p<0.05) pancreas metallothionein (MT) and zinc concentrations in the plasma, tibia and meat, all in quadratic patterns, but linearly decreased (p<0.05) the heterophil/lymphocyte (H/L) ratio. Regarding the different zinc forms, both inorganic and organic zinc increased (p<0.05) the zinc concentrations in the plasma and tibia, the calcium and phosphorus contents in the tibia, and the antioxidant activity of superoxide dismutase in meat as compared to control. An increase in zinc dose increased average daily gain (ADG) and decreased feed conversion ratio (FCR) following a quadratic pattern (p<0.05). Inorganic and organic zinc decreased (p<0.05) FCR and H/L ratio than that of control, but these two forms were similar for these parameters. Conclusion: Zinc addition has a positive impact on immunity and broiler production. Zinc can suppress stress and inhibit the occurrence of lipid peroxidation in broilers, and it can also improve ADG, FCR, and the quality of broiler carcasses.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7237-7241
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• 2013

Background: Smokeless tobacco use in South Asia is believed to be a significant contributor to morbidity and mortality. In India, only a few studies involving health educational intervention by health care providers have demonstrated reduction in smokeless tobacco usage. In the present study we assessed the cessation efforts towards smokeless tobacco by physicians in two high tobacco prevalence states of India. The study also identified opportunities and barriers for integration of tobacco cessation services in routine practices of physicians. Materials and Methods: This mixed method study involved qualitative (phase I) and quantitative research study (phase II). In phase I, 59 in-depth interviews with physicians were conducted. In phase II, a quantitative study conducted among 238 physicians. An inductive approach was followed to analyze qualitative data using ATLAS. Ti software. The Chi-square test was employed to test the association between different variables of interest using SPSS version 17. Results: The majority of physicians related only respiratory problems and cancer with smokeless tobacco. Other major health effects like cardio-vascular problems, oral diseases, and effects on reproductive and neonatal health were recognized only by a few physicians. The age-group of 10-19 years was identified as most vulnerable to smokeless tobacco use. Less than one-third of physicians reported recording smokeless tobacco history of all patients. Findings indicated that less than half of physicians provided information on harmful health effects of smokeless tobacco with regard to specific diseases. Conclusions: The study revealed a low level of knowledge of physicians about harmful effects of tobacco and their suboptimal engagement in tobacco control practices. The study indicates the need of capacity building initiatives to equip physicians with skills in tobacco cessation.

• Journal of Digital Convergence
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• v.18 no.11
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• pp.247-257
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• 2020

The Purpose of this study is to present effective Anti-Drone systems to protect national important facilities against drones that are illegally used by crime groups and terrorists with malicious intents. In order to accomplish the purpose of the study, technical and policy reports regarding Anti-Drone systems, open documents from manufacturers and various research papers are reviewed, and in-depth interviews with experts were conducted. Studies have shown that it is effective to overlay and mix different detection systems so that they can improve detection rates by supplementing each other's advantages and disadvantages, and that the means of incapacitation need to acquire flexibility by using both soft-kill and hard-kill methods in accordance with operational environment for the effective usage. In other words, the establishment of an illegal drone pre-management system, mixed and overlapping detection assets, determining appropriate countermeasures, and multiple distribution of means of incapacitation. The establishment of a protection system for important national facilities through the operation of overlapping and complex anti-drone systems is the most urgent task.

• Journal of Haehwa Medicine
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• v.22 no.1
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• pp.57-70
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• 2013

Objective: Today, the public concern for 'Companion Animal" as a family member is ever increasing. Accordingly, the cases of traditional veterinary medicine treatment targeting a companion animal has been increasing, but the traditional records in literature about this have hardly ever been introduced to academic circles. Hereupon, this writing is intending to collect the prescriptions, which were once used for treating canine diseases, in order to report them to academic circles first. Method: This writing recorded the information about canine diseases and their treatment from the books related to the orthodox oriental medicine in East Asia, and analyzed their meanings. Result: Intial records about canine diseases are found in East Asian traditional medicine books including "Bonchoseubyu"(741), "Ilwhajajegaboncho"(unidentifiable period), "Jeungryuboncho"(1082), etc. The disease perceived by humans at that time was "gwa"(a boil) which is a kind of skin ailments. In addition, these medicine books show that people at that time concentrated on the value of use of a dog as meat rather than a pain of a dog's diseases. "Hwalsujaju"(1873)which was established during the Qing Dynasty leaves the most abundant data on canine diseases. This book perceived a dog as a precious existence watching over human housing and property, according to which, canine diseases and treatment methods are subdivided. The prescriptions for a dog's disease in our country are identifiable only in "Jeungbodanbangshinpyeon"(1913)과 "Bijeongmanbyeongtongchibeop"(1933). These books include the prescriptions not only for a dog's disease but also for a disease of a cow, horse, sheep, chicken, and pig, etc. which are familiar to us. Conclusion: The prescriptions used for a dog in East Asia were different from those for people. It was found that they used a medicine noticeably for external application for easy treatment, and in case of the use of an internal medicine, they adopted a method of getting dogs to take a medicine mixed with rice or porridge for dogs. Such a clue will be applied to the traditional- medicine-based treatment of a companion animal for the time to come.

• Physical Therapy Korea
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• v.25 no.1
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• pp.62-70
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• 2018

Background: Sitting posture influences movements of scapulothoracic and glenohumeral joints and changes the shoulder muscle activities. The development and maintenance of correct sitting posture is important for the fundamental treatment of shoulder pain during rehabilitation. Objects: The purpose of this study was to investigate the effects of the sitting postures and the shoulder movements on shoulder muscle activities for both male and female. Methods: Twenty-eight subjects without shoulder-related diseases participated in this experiment. The subjects had randomly adopted three different sitting postures (upright posture, preferred posture, maximum slouched posture) and shoulder flexion angles in scapular plane ($30^{\circ}$, $90^{\circ}$, $120^{\circ}$). Surface electrodes were collected from upper trapezius (UT), anterior deltoid (AD), and posterior deltoid (PD) and the active shoulder range of motion was measured in each sitting posture and shoulder flexion angle. Results: The active range of motions of the shoulder external rotation and the flexion in the scapular plane decreased from the upright posture to the maximum slouched posture (p<.05, mixed-effect linear regression with random intercept, Tukey post-hoc analysis). All muscles showed the highest EMG activities at $120^{\circ}$ shoulder flexion with the maximum slouched posture and did not show the gender differences. Conclusion: Increased shoulder muscle activities may become the potential risk factor for the shoulder impairment and pain if people continuously maintain the maximum slouched posture. Therefore, an upright position is necessary during shoulder exercises, as well as in activities of daily living, including motions involving lifting the arms.

• Korean Journal of Clinical Pharmacy
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• v.26 no.4
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• pp.312-317
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• 2016

Objective: Midazolam is mainly metabolized by cytochrome P450 (CYP) 3A. Inhibition or induction of CYP3A can affect the pharmacological activity of midazolam. The aims of this study were to develop a population pharmacokinetic (PK) model and evaluate the effect of CYP3A-mediated interactions among ketoconazole, rifampicin, and midazolam. Methods: Three-treatment, three-period, crossover study was conducted in 24 healthy male subjects. Each subject received 1 mg midazolam (control), 1 mg midazolam after pretreatment with 400 mg ketoconazole once daily for 4 days (CYP3A inhibition phase), and 2.5 mg midazolam after pretreatment with 600 mg rifampicin once daily for 10 days (CYP3A induction phase). The population PK analysis was performed using a nonlinear mixed effect model ($NONMEM^{(R)}$ 7.2) based on plasma midazolam concentrations. The PK model was developed, and the first-order conditional estimation with interaction was applied for the model run. A three-compartment model with first-order elimination described the PK. The influence of ketoconazole and rifampicin, CYP3A5 genotype, and demographic characteristics on PK parameters was examined. Goodness-of-fit (GOF) diagnostics and visual predictive checks, as well as bootstrap were used to evaluate the adequacy of the model fit and predictions. Results: Twenty-four subjects contributed to 900 midazolam concentrations. The final parameter estimates (% relative standard error, RSE) were as follows; clearance (CL), 31.8 L/h (6.0%); inter-compartmental clearance (Q) 2, 36.4 L/h (9.7%); Q3, 7.37 L/h (12.0%), volume of distribution (V) 1, 70.7 L (3.6%), V2, 32.9 L (8.8%); and V3, 44.4 L (6.7%). The midazolam CL decreased and increased to 32.5 and 199.9% in the inhibition and induction phases, respectively, compared to that in control phase. Conclusion: A PK model for midazolam co-treatment with ketoconazole and rifampicin was developed using data of healthy volunteers, and the subject's CYP3A status influenced the midazolam PK parameters. Therefore, a population PK model with enzyme-mediated drug interactions may be useful for quantitatively predicting PK alterations.