• Title/Summary/Keyword: Mix-Method

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The effect of aromatherapy on pain in individuals with diabetes: a systematic review and meta-analysis

  • Mi-Kyoung Cho;Mi Young Kim
    • Journal of Korean Biological Nursing Science
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    • v.26 no.2
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    • pp.71-82
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    • 2024
  • Purpose: This study systematically analyzed the impact of aromatherapy on pain in individuals with diabetes. Methods: A search was performed in seven electronic databases based on the PICO-SD (Population, Intervention, Comparison, Outcome, Study Design) framework. The population (P) of interest was individuals with diabetes, and the intervention (I) included aromatherapy targeting pain reduction. The comparison (C) consisted of control groups that received no intervention, another intervention, or usual care. The outcome (O) measured was pain. The quality of the selected literature was assessed using the Joanna Briggs Institute checklist. In MIX 2.0 Pro, the pooled overall effect of pain was calculated using Hedge's g and a random-effects model, and heterogeneity was calculated using the Q statistic and Higgin's I2 values. Meta-regression and exclusion sensitivity analyses were performed. Results: Five articles and seven studies were included, showing a significant pooled overall effect of aromatherapy on diabetes-related pain (Hedge's g = -1.83, 95% CI: -2.76 to -0.91). Meta-regression demonstrated that effectiveness in reducing pain was associated with studies conducted in West Asia, those with IRB approval, and those receiving funding. Additionally, interventions involving subjects under 60, lavender oil (vs. turpentine oil or blended oils), massage therapy (vs. topical application), fewer hours per session, and more repeated measurements (vs. pre/post measurements) were associated with pain reduction. Conclusion: Aromatherapy, especially with lavender oil, effectively manages diabetes-related pain. Short-duration massage application is also effective. A personalized selection of oil type and application method could optimize therapeutic outcomes for individuals with diabetes.

Comparison and Characterization of Silodosin-loaded Solid Dispersions Prepared by Various Solid Dispersion Preparation Methods (다양한 고체분산체 제조방법으로 제조한 실로도신 함유 고체분산체의 비교 및 특성분석)

  • Su Man Lee;Da Young Song;Kyeong Soo Kim
    • Journal of Powder Materials
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    • v.31 no.3
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    • pp.263-271
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    • 2024
  • This study focused on improving the solubility of silodosin, a drug poorly soluble in water, by utilizing solid dispersions. Three types of dispersions were examined and compared against the drug powder: surface-attached (SA), solvent-wetted (SW), and solvent-evaporated (SE). Polyvinyl alcohol (PVA) was identified as the most effective polymer in enhancing solubility. These dispersions were prepared using spray-drying techniques with silodosin and PVA as the polymer, employing solvents such as water, ethanol, and a water-acetone mix. The physicochemical properties and solubility of the dispersions were evaluated. The surface-attached dispersions featured the polymer on a crystalline drug surface, the solvent-wetted dispersions had the amorphous drug on the polymer, and the solvent-evaporated dispersions produced nearly round particles with both components amorphous. Testing revealed that the order of improved solubility was: solvent-evaporated, solvent-wetted, and surface-attached. The results demonstrated that the preparation method of the solid dispersions significantly impacted their physicochemical properties and solubility enhancement.

Rearing Method for Ascotis selenaria (Lepidoptera: Geometridae) using an Artificial Diet (인공사료를 이용한 네눈쑥가지나방(Ascotis selenaria)(나비목: 자나방과) 실내 사육법)

  • Choi, Kyung-San;Park, Young-Mi;Kim, Dong-Soon
    • Korean journal of applied entomology
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    • v.50 no.1
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    • pp.55-63
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    • 2011
  • This study was conducted to develop an artificial diet for the mugwort looper, Ascotis selenaria (Lepidoptera: Geometridae), which is an insect pest to leaves of citrus (Citrus unshiu). Corn and soybean powder were selected as main nutrient sources for larvae of A. selenaria after several diets consisted of wheat germ, corn, kidney bean and/or soybean were tested for larval development and survival. A higher amount of the main nutrients in the diet increased the larval survivorship. Addition of yeast and cholesterol in diet increased the larval survivorship. Finally the composition of diet was decided as followings; corn 100 g, soybean 100 g agar 25 g, Brewers' yeast 30 g, cholesterol 0.5 g, Vanderzant vitamin mixture 2 g, Wesson's salt mixture 2 g, sorbic acid 2 g, ascorbic acid 2 g, and methyl-4-hydroxybenzoate 2.5 g, and distilled water 1 liter. Development periods of larvae and pupae, survival rate and fecundity of A. selenaria reared on the diet were not significantly different with those on the host plant, citrus leaves. Larvae of early instars were reared in a group, while larvae of later instars (5-6th) were reared individually. Adult mating was conducted in a plastic cage and an oilpaper covered with a gauze was provided as an oviposition site.

Economic Analysis of Long-life Asphalt Pavements using KoPMS (한국형 포장관리시스템을 활용한 장수명 아스팔트 포장의 경제성 분석)

  • Do, Myungsik;Kwon, Sooahn;Baek, Jongeun;Choi, Seunghyun
    • International Journal of Highway Engineering
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    • v.18 no.4
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    • pp.19-28
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    • 2016
  • PURPOSES : Long-life asphalt pavements are used widely in developed countries. In order to be able to devise an effective maintenance strategy for such pavements, in this study, we evaluated the performance of the long-life asphalt pavements constructed along the national highways in South Korea. Further, an economic evaluation of the long-life asphalt pavements was performed based on a life-cycle cost analysis. We aimed to devise a model for evaluating the performance of long-life asphalt pavements using the national highway pavement management system (PMS) database as well as for analyzing the economic feasibility of such pavements, in order to promote their use in South Korea. METHODS : The maintenance history and pavement performance data were obtained from the national highway PMS database. The pavement performances for a total of 292 sections of 10 lanes (5 northbound lanes and 5 eastbound lanes) of national highways were used in this study. Models to predict the performances of hot mix asphalt (HMA) and long-life asphalt pavements under two distinct traffic conditions were developed using a simple regression method. Further, the economic feasibility of long-life asphalt pavements was evaluated using the Korea Pavement Management System (KoPMS). RESULTS : We developed service-life prediction models based on the traffic volume and the equivalent of single-axle load and found that long-life asphalt pavements have service lives 50% longer than those of HMA pavements. Further, the results of the economic analysis showed that long-life asphalt pavements are superior in terms of various economic indexes, including user cost, delay cost, total cost, and user benefits, even though their maintenance cost is higher than that of HMA pavements. A comparison of the economic feasibilities of the various groups showed that group A is superior to HMA pavements in all aspects except in terms of the maintenance criterion (crack 20% or higher) as per the NPV index. However, the long-life asphalt pavements in group B were superior in terms of the maintenance criterion (crack 25% or higher) regardless of the economic feasibility. CONCLUSIONS : The service life of long-life asphalt pavements was found to be approximately 50% longer than that of HMA pavements, regardless of the traffic volume characteristics. The economic feasibility of long-life asphalt pavements was evaluated based on the KoPMS. The results of the economic analysis were the following: long-life asphalt pavements are exceptional in terms of almost all factors, such as user cost, delay cost, total cost, and user benefit; however, the exception is the maintenance cost. Further, the economic feasibility of the long-life asphalt pavements in group B was found to be better than that of the HMA pavements (crack 25% or higher).

Effect of Salts and Isomeric Butanols on the Mixed Micellar Properties of Cetylpyridinium Chloride with Triton X-100 (Cetylpyridinium Chloride와 Triton X-100의 혼합 미셀화에 미치는 염 및 부탄올 이성질체들의 효과)

  • Chung, Jong-Jae;Lee, Sang-Hak;Kim, Yung-Cheol;Lee, Byung-Hwan
    • Applied Chemistry for Engineering
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    • v.9 no.7
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    • pp.968-973
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    • 1998
  • The critical micelle concentrations($CMC^*$) of the mixed surfactant systems of cationic surfactant cetylpyridinium chloride(CPC) and nonionic surfactant Triton X-100(TX-100) in aqueous solutions of salts(KCl and $Na_2CO_3$) and isomeric butanols(tert-butanol, iso-butanol and n-butanol) were determined by UV spectroscopy method. The various thermodynamic values in aqueous solutions of salts and isomeric butanols were compared with the values in pure water, calculated by means of the equation derived from the pseudo-phase separation model. Thermodynamic parameters($X_1$, $\beta$, ${\gamma}i$, $ai^M$, $C_i$ and ${\Delta}H_{mix}$) were found to have great effects of salts and isomeric butanols on the mixed micellization of CPC/TX-100 mixtures, and also in good agreements with the nonideal mixed micelle model. They showed all negative deviations from the ideal mixed micellar behavior.

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A Study on Hybrid Expressed in Modern Fashion - Focusing on the End of 1990s - (현대패션에 표현된 하이브리드 경향 연구 - 1990년대 후반을 중심으로 -)

  • 임영자;한윤숙
    • Journal of the Korean Society of Costume
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    • v.51 no.5
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    • pp.113-134
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    • 2001
  • This study was carried out with an objective to prepare the framework of conformity for the 21st century modern fashion, which is interactive with mankind, based on a position that the 21st century contemporary fashion with its amalgamating trend of diversified artistic forms may not be elucidated on a standpoint centering on one certain modality. The hybrid fashion trend of historical modality which provides freedom and satisfaction in creation of an individuals expressive power in expressing true desire of mans inside through man-centered thought of the times has made multifarious motives of the past and present fragmentary. It thus extracts inner divisions and the concept of consolidation through three-dimensional form. Modern fashion is newly interpreted by the material and details of high technologies. and is harmonized by mix and match with various expressions. By having it, it is being expressed together with many types of dresses and ornaments. Modern fashion is being expressed together with many types of dresses and ornaments by new interpretations with the material and details of high technologies and by being harmonized with mix and match with various expressions. The hybrid fashion design trend of regional elements formed by stimuli and contacts of diverse local culture by globalization of network that was achieved by scientific technologies of the contemporary information society has disintegrated varied boundaries in the conventional culture by the latest communication technology-new media on the basis of newly created culture. The fact that regional elements could be expressed as if they were interrelated without each being deprived of originality may be explained with an interpretation on pluralism. The hybrid fashion design trend of cultural aspect, which manifests in the background of scientific technological culture as it transcends the societal-cultural boundaries based on the de-centralization theory of Frederic Jameson, has supplemented the imperfect meanings through conversional correlation with other forms and internal program changes. The middle stratal and polyhedral characteristics are seen as each cultural element is dismantled and reassembled by application of 'multiple-time point expression'. Design forming method is not to bring destruction from outside, but to embrace instability and chaos through radical dismantling of the inside. and to pursue diversity and openness. Thus. it is implemented by an approach that takes the role of design process. In communication of discontinuity, continuity was dismantled through forms of mixing, overlap, perversion, insertion and coincidence.

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Micropropagation of Juvenile and mature Trees of Sawtooth Oak (Quercus acutissima C.) (상수리나무 유목(幼木)과 성숙목(成熟木)의 기내번식(器內繁殖))

  • Moon, Heung Kyu;Youn, Yang;Yi, Jae Seon
    • Journal of Korean Society of Forest Science
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    • v.86 no.3
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    • pp.391-398
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    • 1997
  • Present study describes a method on the application of efficient tissue culture systems for the micro-propagation of juvenile and mature sawtooth oak(Quercus acutissima). Nodal segments with axillary buds were used as initial explant sources. WPM(Woody Plant Medium) was the best in growth and proliferation of shoot among the media tested. Although the single effect of zeatin revealed on two dorminant shoot elongation with normal growth until the elevation of levels up to 3.0mg/l, BAP($N^6$-benzyl amino purine) usually showed better response than zeatin on shoot multiplication and/or elongation. In addition, the incorporation of BAP and zeatin onto the culture media represents more effectiveness in shoot proliferation and its growth. Optimum concentrations of BAP and zeatin were 0.5 and 0.05~1.0mg/l, respectively. Ninety percent of the proliferated shoots was rooted on half-strength GD (Gresshoff and Doy, 1972) medium containing 0.5mg/l IBA(indole butyric acid) in 4 weeks after culture. More than 70% of the rooted plantlets survived after 5 months of transplanting into artificial soil mix containing equal amount of peatmoss and perlite. Among 27 plus tree clones which were grafted twice onto the juvenile rootstocks, only 4 clones revealed the possibility for shoot multiplication through tissue culture system. The capacity for the micropropagation using mature explant sources was highly depended on clonal differences compared with those of octet age. More than 90% of rooting ratio was obtained from the best responding clone. Among the 7 rooting media tested, GD medium was the best far rooting. The most effective rooting was obtained on half-strength GD medium containing 0.2 to 2.0mg/l IBA. More than 60% of rooted plantlets survived after 5 months of transplanting into the artificial soil mix.

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Study on the Micellization of CPC/Brij 35 Mixed Surfactant Systems in Water (순수 물에서 CPC/Brij 35 혼합계면활성제의 미셀화에 대한 연구)

  • Gil, Han-Nae;Lee, Byung-Hwan
    • Journal of the Korean Chemical Society
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    • v.53 no.2
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    • pp.118-124
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    • 2009
  • The values of critical micelle concentration (CMC) and counter ion binding constants (B) in a micellar state of CPC (1-hexadecylpyridinium chloride) with Brij 35 (polyoxyethylene(23) lauryl ether) in water were determined as a function of ${\alpha}_1$ (the overall mole fraction of CPC) by the use of electric conductivity method. Various thermodynamic parameters ($X_i,\;{\gamma}_i,\;C_i,\;a_{i}^{M},\;\beta,\;and\;{\Delta}H_{mix}$) were calculated and analyzed by means of the equations derived from the non-ideal mixed micellar model. And thermodynamic parameters (${\Delta}{G^o}_m,\;{\Delta}{H^o}_m,\;and\;{\Delta}{S^o}_m$) for the micellization of CPC/Brij 35 mixtures were also calculated from the temperature dependence of the CMC values. The values of ${\Delta}{G^o}_m$ are all negative, but the values of ${\Delta}{S^o}_m$ and ${\Delta}{H^o}_m$ are positive or negative, depending on the measured temperature and ${\alpha}_1$.

Quality Control Method for the Concrete from Multiple Suppliers (콘크리트 혼합타설시 품질확보 방안)

  • Kim, Kyung-Hoon;Lee, Sang-Hak
    • Journal of the Korea Institute of Building Construction
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    • v.18 no.3
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    • pp.227-234
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    • 2018
  • Concrete mix design controls the various concrete properties such as workability and strength. Fresh concrete requires workability and the hardened concrete requires compressive strength. If using the concrete from different supplier concurrently, the concrete placed can show different properties unlike originally designed. However most of construction sites place the concrete from several companies. One of the predictable problems is whether the ultimate performance of concrete achieves the originally designed performance after placing the concrete from several companies. Therefore this research aims to keep the concrete quality in the above cases. This research has been done through literature review, questionnaire and the verification at the sample construction site. A literature review describes the general characteristics and quality control of concrete and a questionnaire describes the awareness and implementation of Korean Construction Specification(KCS). The production capacity and the delivery capacity of concrete suppliers is smaller than the daily quantity required on the sample site, therefore the placing of the concrete with different mixing ratio is inevitable and it can not keep the KCS. As a conclusion, this research proposed 5 alternatives and one of them has been adopted, i.e. to unify the concrete mix design of multiple concrete suppliers.

A Comparative Study on Power Tool Manufacturers' Products Spec. and Design Development Features - By the Case Study on BOSCH, BLACK&DECKER and KEYANG Electrics- (전동공구 회사의 제품사양별 디자인개발특성 비교연구 -보슈(BOSCH), 블랙앤데커(BLACK&DECKER), 계양전기 사례를 중심으로 -)

  • 채승진
    • Archives of design research
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    • v.17 no.1
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    • pp.383-392
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    • 2004
  • The power tools is the product using working power generated by electric motor. Many companies are manufacturing numerous devices. Main features of tools are included various assembled products, small, light and solid and durable enough to match several standards. Fundamental requirements for the product is excellent performance and convenience for use. The quality of them depends on the equipped motor'(s) capability, accuracy of gear and endurance against worn-out. By adapting the state-of-the-art parts, they could be used in the place from home to heavy industry broadly. They can be classified electronic drills, grinders, saws and sanders families for the household appliances. For industrial tools, bore drill, grinder, polisher, and driver drill are classified as special and high priced group. This study presents the strategy of power tool development of BOSCH, BLACK&DECKER and KEYANG. Their products were analyzed in terms of product line and product mix concept. Then they are examined by design elements, such as color, shape and material for housing. As an analysis method, the image scale parameter and criteria were applied to each company's product.

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